IT1241984B - Impiego di uridina nel trattamento farmacologico delle complicazioni periferiche del diabete - Google Patents

Impiego di uridina nel trattamento farmacologico delle complicazioni periferiche del diabete

Info

Publication number
IT1241984B
IT1241984B IT48057A IT4805790A IT1241984B IT 1241984 B IT1241984 B IT 1241984B IT 48057 A IT48057 A IT 48057A IT 4805790 A IT4805790 A IT 4805790A IT 1241984 B IT1241984 B IT 1241984B
Authority
IT
Italy
Prior art keywords
uridine
diabetes
pharmacological treatment
complications
peripheral
Prior art date
Application number
IT48057A
Other languages
English (en)
Other versions
IT9048057A0 (it
IT9048057A1 (it
Inventor
Vincenzo Politi
Luca Giovanna De
Stazio Giovanni Di
Mario Materazzi
Original Assignee
Polifarma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Polifarma Spa filed Critical Polifarma Spa
Priority to IT48057A priority Critical patent/IT1241984B/it
Publication of IT9048057A0 publication Critical patent/IT9048057A0/it
Priority to EP91830170A priority patent/EP0462075B1/en
Priority to DE69123178T priority patent/DE69123178T2/de
Priority to US07/704,230 priority patent/US5190948A/en
Priority to JP3139928A priority patent/JP2830955B2/ja
Publication of IT9048057A1 publication Critical patent/IT9048057A1/it
Application granted granted Critical
Publication of IT1241984B publication Critical patent/IT1241984B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT48057A 1990-06-13 1990-06-13 Impiego di uridina nel trattamento farmacologico delle complicazioni periferiche del diabete IT1241984B (it)

Priority Applications (5)

Application Number Priority Date Filing Date Title
IT48057A IT1241984B (it) 1990-06-13 1990-06-13 Impiego di uridina nel trattamento farmacologico delle complicazioni periferiche del diabete
EP91830170A EP0462075B1 (en) 1990-06-13 1991-04-26 Use of uridine in the pharmacological treatment of the peripheral complications of diabetes
DE69123178T DE69123178T2 (de) 1990-06-13 1991-04-26 Verwendung von Uridin zur pharmakologischen Behandlung der peripheren Komplikationen bei Diabetes
US07/704,230 US5190948A (en) 1990-06-13 1991-05-22 Use of uridine in the pharmacological treatment of the peripheral complications of diabetes
JP3139928A JP2830955B2 (ja) 1990-06-13 1991-06-12 糖尿病の末梢合併症を薬理的に治療する際に使用するためのウリジン

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT48057A IT1241984B (it) 1990-06-13 1990-06-13 Impiego di uridina nel trattamento farmacologico delle complicazioni periferiche del diabete

Publications (3)

Publication Number Publication Date
IT9048057A0 IT9048057A0 (it) 1990-06-13
IT9048057A1 IT9048057A1 (it) 1991-12-13
IT1241984B true IT1241984B (it) 1994-02-02

Family

ID=11264248

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48057A IT1241984B (it) 1990-06-13 1990-06-13 Impiego di uridina nel trattamento farmacologico delle complicazioni periferiche del diabete

Country Status (5)

Country Link
US (1) US5190948A (it)
EP (1) EP0462075B1 (it)
JP (1) JP2830955B2 (it)
DE (1) DE69123178T2 (it)
IT (1) IT1241984B (it)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3459013B2 (ja) * 1993-05-19 2003-10-20 株式會社緑十字 ウリジンを有效成分とする關節炎治療剤
US5852000A (en) * 1993-08-25 1998-12-22 Otsuka Pharmaceutical Factory, Inc. Cardiac rehabilitation agent
IT1290781B1 (it) * 1996-05-28 1998-12-10 Polifarma Spa Agente attivo terapeutico per il trattamento di malattie degenerative neuronali.
US5962459A (en) * 1996-05-28 1999-10-05 Polifarma S.P.A. Therapeutic active agent for treatment of neuron degenerative diseases
US8314064B2 (en) 1998-07-31 2012-11-20 Massachusetts Institute Of Technology Uridine administration stimulates membrane production
US8518882B2 (en) 1998-07-31 2013-08-27 Massachusetts Institute Of Technology Methods and compositions for ameliorating or inhibiting decline in memory or intelligence or improving same
US8143234B2 (en) 1998-07-31 2012-03-27 Massachusetts Institute Of Technology Uridine administration improves phosphatide synthesis, synaptic transmission and cognitive function
US6472378B2 (en) * 1998-08-31 2002-10-29 Pro-Neuron, Inc. Compositions and methods for treatment of mitochondrial diseases
US7915233B1 (en) 1998-08-31 2011-03-29 Wellstat Therapeutics Corporation Compositions and methods for treatment of mitochondrial diseases
US7807654B2 (en) 1998-08-31 2010-10-05 Wellstat Therapeutics Corporation Compositions and methods for treatment of mitochondrial diseases
RU2394580C2 (ru) 1999-02-23 2010-07-20 Дзе Риджентс Оф Дзе Юниверсити Оф Калифорния Способы лечения митохондриальных нарушений
SE521031C2 (sv) * 1999-05-05 2003-09-23 Srinivas Uppugunduri Nya specifika inhibitorer av akut och kronisk inflammation
PL209031B1 (pl) * 2001-04-30 2011-07-29 Trommsdorff Arzneimittel Estry urydyny, ich zastosowanie i sposób wytwarzania, oraz kompozycje farmaceutyczne je zawierające
CA2566612C (en) * 2004-05-13 2015-06-30 Massachusetts Institute Of Technology Uridine effects on dopamine release
US8551452B2 (en) 2007-11-02 2013-10-08 Massachusetts Institute Of Technology Uridine dietary supplementation compliance methods and use thereof
DE102012111674A1 (de) * 2012-11-30 2014-06-05 Universität Rostock Nukleosidderivate zur Behandlung von Diabetes mellitus
WO2018218287A1 (en) * 2017-05-29 2018-12-06 Woodlinda Pty Ltd Treatment and/or prevention of neuropathic symptoms associated with diabetes mellitus type ii
CN121154665B (zh) * 2025-11-21 2026-02-27 天津医科大学第二医院 尿苷在防治糖尿病肾病药物开发过程中及药物中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0339075B1 (en) * 1987-10-28 1993-08-18 Pro-Neuron, Inc. Acylated uridine and cytidine and uses thereof

Also Published As

Publication number Publication date
DE69123178D1 (de) 1997-01-02
US5190948A (en) 1993-03-02
EP0462075A2 (en) 1991-12-18
EP0462075B1 (en) 1996-11-20
DE69123178T2 (de) 1997-05-28
IT9048057A0 (it) 1990-06-13
JP2830955B2 (ja) 1998-12-02
IT9048057A1 (it) 1991-12-13
JPH04243830A (ja) 1992-08-31
EP0462075A3 (en) 1992-01-15

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960621