DK3182980T3 - Behandling af glykosyleringsmangelsygdomme - Google Patents

Behandling af glykosyleringsmangelsygdomme Download PDF

Info

Publication number
DK3182980T3
DK3182980T3 DK15833822.8T DK15833822T DK3182980T3 DK 3182980 T3 DK3182980 T3 DK 3182980T3 DK 15833822 T DK15833822 T DK 15833822T DK 3182980 T3 DK3182980 T3 DK 3182980T3
Authority
DK
Denmark
Prior art keywords
glycosyling
treatment
deficiency diseases
deficiency
diseases
Prior art date
Application number
DK15833822.8T
Other languages
English (en)
Inventor
Borstel Reid W Von
Original Assignee
Wellstat Therapeutics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellstat Therapeutics Corp filed Critical Wellstat Therapeutics Corp
Application granted granted Critical
Publication of DK3182980T3 publication Critical patent/DK3182980T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7012—Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK15833822.8T 2014-08-19 2015-08-19 Behandling af glykosyleringsmangelsygdomme DK3182980T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462039052P 2014-08-19 2014-08-19
PCT/US2015/045896 WO2016028894A1 (en) 2014-08-19 2015-08-19 Treatment of glycosylation deficiency diseases

Publications (1)

Publication Number Publication Date
DK3182980T3 true DK3182980T3 (da) 2021-01-11

Family

ID=55351228

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15833822.8T DK3182980T3 (da) 2014-08-19 2015-08-19 Behandling af glykosyleringsmangelsygdomme

Country Status (6)

Country Link
US (2) US20170209476A1 (da)
EP (1) EP3182980B1 (da)
DK (1) DK3182980T3 (da)
ES (1) ES2841745T3 (da)
PL (1) PL3182980T3 (da)
WO (1) WO2016028894A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210187001A1 (en) * 2018-02-01 2021-06-24 Wellstat Therapeutics Corporation Compositions and Devices for Systemic Delivery of Uridine
AU2019285303A1 (en) * 2018-06-14 2020-12-17 Katholieke Universiteit Leuven, K.U. Leuven R&D Methods and materials for treating glycosylation disorders
MX2023002868A (es) * 2020-09-14 2023-03-24 Wellstat Therapeutics Corp 2',3'-diacetiluridina sustituida por acetoacetilo en la posicion 5'.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL144964A0 (en) * 1999-02-23 2002-06-30 Pro Neuron Inc Methods of treatment of mitochondrial disorders
WO2007064691A1 (en) * 2005-12-02 2007-06-07 Nabil Habib Lab Treatment of cancer and other diseases
US20120078529A1 (en) * 2009-05-13 2012-03-29 Wellstat Therapeutics Corporation Determining the severity of 5-fluorouracil overdose
US20110257233A1 (en) * 2010-03-19 2011-10-20 Sanford-Burnham Medical Research Institute Benzoisothiazolones as inhibitors of phosphomannose isomerase
US20150045416A1 (en) * 2012-01-05 2015-02-12 Hadasit Medical Research Services & Development Ltd. Methods and Compositions for Gene Delivery

Also Published As

Publication number Publication date
US20220273688A1 (en) 2022-09-01
EP3182980A1 (en) 2017-06-28
EP3182980B1 (en) 2020-10-14
EP3182980A4 (en) 2018-06-06
PL3182980T3 (pl) 2021-04-19
ES2841745T3 (es) 2021-07-09
WO2016028894A1 (en) 2016-02-25
US20170209476A1 (en) 2017-07-27

Similar Documents

Publication Publication Date Title
DK3134530T3 (da) Behandling af hyperbilirubinæmi
DK3212233T3 (da) Kombinationsterapi til behandling af sygdom
DK3137169T3 (da) Hæmmere af lysin-specifik demethylase-1
DK3240612T3 (da) Fremgangsmåder til behandling af nethindesygdomme
DK3450553T3 (da) Mrna-terapi til behandling af øjensygdomme
DK3171928T3 (da) Stimulationsmønstre til behandling af tørt øje
DK3125875T3 (da) Inhalerbar rapamycinformulering til behandling af aldersrelaterede tilstande
DK3169328T3 (da) Quinolinderivater til behandling af inflammationssygdomme
DK3390390T3 (da) Bipyrazolylderivater egnede til behandling af autoimmunsygdomme
DK3231444T3 (da) Ny behandling
DK3307267T3 (da) Behandling af multipel sklerose
DK3132009T3 (da) Fremgangsmåde
DK3283210T3 (da) Fremgangsmåde
DK3237621T3 (da) Varianter af human alpha-galactosidase
DK3166628T3 (da) Terapeutisk anvendelse af knoglemorfogenetiske proteiner
DK3164394T3 (da) Gls1-inhibitorer til behandling af sygdomme
DK3164123T3 (da) Hidtil ukendte anvendelser af benzylidenguanidinderivater til behandling af proteopatier
DK3097085T3 (da) Benzoxazinonderivater til behandling af hudsygdomme
DK3368044T3 (da) Behandling af hepatisk steatose-relateret oligo-ovulation
DK3297619T3 (da) Terapeutiske anvendelser af L-4-chlorkynurenin
DK3151814T3 (da) Behandling af en hudlæsion
DK2897382T3 (da) Forbedring af binaural kilde
DK3374495T3 (da) Forbedrede fremgangsmåder til vævsfremstilling
DK3848028T3 (da) Fremgangsmåder til behandling af øjenlidelser
DK3096775T3 (da) SOCS-mimetika til behandling af sygdomme