JP2002534531A5 - - Google Patents
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- Publication number
- JP2002534531A5 JP2002534531A5 JP2000593622A JP2000593622A JP2002534531A5 JP 2002534531 A5 JP2002534531 A5 JP 2002534531A5 JP 2000593622 A JP2000593622 A JP 2000593622A JP 2000593622 A JP2000593622 A JP 2000593622A JP 2002534531 A5 JP2002534531 A5 JP 2002534531A5
- Authority
- JP
- Japan
- Prior art keywords
- desdimethylamino
- macrolides
- dehydroerythromycin
- hoffman
- robinson
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003120 macrolide antibiotic agent Substances 0.000 description 3
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 description 2
- 229940041033 macrolides Drugs 0.000 description 2
- 102000003886 Glycoproteins Human genes 0.000 description 1
- 108090000288 Glycoproteins Proteins 0.000 description 1
- 102000000589 Interleukin-1 Human genes 0.000 description 1
- 108010002352 Interleukin-1 Proteins 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 230000027455 binding Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 description 1
- 229960003276 erythromycin Drugs 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 150000002923 oximes Chemical class 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1999MI000061A IT1306205B1 (it) | 1999-01-15 | 1999-01-15 | Macrolidi ad attivita' antiinfiammatoria. |
| IT99A000061 | 1999-07-30 | ||
| PCT/EP2000/000163 WO2000042055A2 (en) | 1999-01-15 | 2000-01-12 | Macrolides with anti-inflammatory activity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002534531A JP2002534531A (ja) | 2002-10-15 |
| JP2002534531A5 true JP2002534531A5 (enExample) | 2006-12-28 |
| JP4568433B2 JP4568433B2 (ja) | 2010-10-27 |
Family
ID=11381492
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000593622A Expired - Fee Related JP4568433B2 (ja) | 1999-01-15 | 2000-01-12 | 抗炎症活性を有するマクロライド |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6455576B1 (enExample) |
| EP (1) | EP1144427B1 (enExample) |
| JP (1) | JP4568433B2 (enExample) |
| CN (1) | CN1151165C (enExample) |
| AT (1) | ATE308552T1 (enExample) |
| AU (1) | AU769006B2 (enExample) |
| BR (1) | BR0007514A (enExample) |
| CA (1) | CA2368400C (enExample) |
| DE (1) | DE60023647T2 (enExample) |
| ES (1) | ES2251966T3 (enExample) |
| HU (1) | HU229228B1 (enExample) |
| IL (2) | IL144044A0 (enExample) |
| IT (1) | IT1306205B1 (enExample) |
| MX (1) | MXPA01007164A (enExample) |
| NO (1) | NO318982B1 (enExample) |
| RU (1) | RU2243230C2 (enExample) |
| SK (1) | SK286772B6 (enExample) |
| WO (1) | WO2000042055A2 (enExample) |
| ZA (1) | ZA200105748B (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20010018A2 (en) | 2001-01-09 | 2002-12-31 | Pliva D D | Novel anti-inflammatory compounds |
| NZ537717A (en) | 2002-07-08 | 2006-04-28 | Pliva Istrazivacki Inst D | New compounds, compositions and methods for treatment of inflammatory diseases and conditions |
| PL374646A1 (en) * | 2002-07-08 | 2005-10-31 | Pliva-Istrazivacki Institutt D.O.O. | Novel nonsteroidal anti-inflammatory substances, compositions and methods for their use |
| DE60327341D1 (de) * | 2002-07-08 | 2009-06-04 | Glaxosmithkline Zagreb | Hybridmoleküle von makroliden mit steroidalen/nicht-steroidalen antientzündlich aktiven molekülen |
| ITMI20021726A1 (it) * | 2002-08-01 | 2004-02-02 | Zambon Spa | Macrolidi ad attivita' antiinfiammatoria. |
| AR043050A1 (es) | 2002-09-26 | 2005-07-13 | Rib X Pharmaceuticals Inc | Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos |
| ITMI20022292A1 (it) * | 2002-10-29 | 2004-04-30 | Zambon Spa | 9a-azalidi ad attivita' antiinfiammatoria. |
| CA2521462A1 (en) | 2003-04-17 | 2004-10-28 | Sandoz Ag | Derivatives of azithromycin |
| HRP20030324A2 (en) | 2003-04-24 | 2005-02-28 | Pliva-Istra�iva�ki institut d.o.o. | Compounds of antiinflammatory effect |
| ITMI20040124A1 (it) * | 2004-01-29 | 2004-04-29 | Zambon Spa | Macrolidi ad attivita' antiinfiammatoria |
| WO2006130128A2 (en) * | 2004-02-18 | 2006-12-07 | Chiron Corporation | Methods of identifying anti-inflammatory macrolides |
| JP5383037B2 (ja) | 2004-02-27 | 2014-01-08 | リブ−エックス ファーマシューティカルズ，インコーポレイテッド | 大環状化合物およびそれらを製造し使用する方法 |
| WO2006035301A2 (en) * | 2004-09-27 | 2006-04-06 | Ranbaxy Laboratories Limited | Erythromycin a derivatives as antibacterial agents |
| WO2006046123A2 (en) | 2004-10-27 | 2006-05-04 | Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. | Conjugates with anti-inflammatory activity |
| US20080249034A1 (en) * | 2005-03-21 | 2008-10-09 | Zambon S.P.A. | Use of Macrolides for Treating Intestinal Inflammation |
| US7582611B2 (en) * | 2005-05-24 | 2009-09-01 | Pfizer Inc. | Motilide compounds |
| WO2011090940A1 (en) | 2010-01-19 | 2011-07-28 | Cerulean Pharma Inc. | Cyclodextrin-based polymers for therapeutic delivery |
| RU2455309C2 (ru) * | 2010-07-20 | 2012-07-10 | Открытое Акционерное Общество "Татхимфармпрепараты" | Способ получения аморфной формы рокситромицина |
| GB201608236D0 (en) | 2016-05-11 | 2016-06-22 | Fidelta D O O | Seco macrolide compounds |
| US11771677B2 (en) | 2020-03-12 | 2023-10-03 | Zoetis Services Llc | Immunomodulating urea azalides |
| US20230131943A1 (en) | 2020-03-24 | 2023-04-27 | Burnet Micheal W | Anti-infective and anti-viral compounds and compositions |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3928387A (en) * | 1974-02-04 | 1975-12-23 | Hoffmann La Roche | Antibiotic 1745A/X and methods for the production thereof |
| IT1189285B (it) * | 1982-05-28 | 1988-02-04 | Nuovo Consor Sanitar Nazionale | Sali dell'antibiotico eritromicina e del suo estere propionico con acidi ad attivita' terapeutica coadiuvante |
| EP0254534A3 (en) * | 1986-07-24 | 1991-04-17 | William S. Robinson | Erythromycin derivatives and compositions and use for inhibiting virus replication and disease |
| FR2697524B1 (fr) * | 1992-11-05 | 1994-12-23 | Roussel Uclaf | Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments. |
| IT1276901B1 (it) * | 1994-12-13 | 1997-11-03 | Zambon Spa | Derivati dell'eritromicina a 9-0-ossina dotati di attivita' antibiotica |
| KR19980701895A (ko) * | 1995-03-08 | 1998-06-25 | 이라우치지마 가즈다카 | 면역관련병 처치제 및 그의 탐색 방법 |
-
1999
- 1999-01-15 IT IT1999MI000061A patent/IT1306205B1/it active
-
2000
- 2000-01-12 AT AT00904899T patent/ATE308552T1/de not_active IP Right Cessation
- 2000-01-12 ES ES00904899T patent/ES2251966T3/es not_active Expired - Lifetime
- 2000-01-12 SK SK981-2001A patent/SK286772B6/sk not_active IP Right Cessation
- 2000-01-12 BR BR0007514-0A patent/BR0007514A/pt not_active IP Right Cessation
- 2000-01-12 WO PCT/EP2000/000163 patent/WO2000042055A2/en not_active Ceased
- 2000-01-12 MX MXPA01007164A patent/MXPA01007164A/es unknown
- 2000-01-12 CN CNB008027676A patent/CN1151165C/zh not_active Expired - Fee Related
- 2000-01-12 AU AU26636/00A patent/AU769006B2/en not_active Ceased
- 2000-01-12 CA CA002368400A patent/CA2368400C/en not_active Expired - Fee Related
- 2000-01-12 IL IL14404400A patent/IL144044A0/xx active IP Right Grant
- 2000-01-12 HU HU0105105A patent/HU229228B1/hu not_active IP Right Cessation
- 2000-01-12 DE DE60023647T patent/DE60023647T2/de not_active Expired - Lifetime
- 2000-01-12 RU RU2001118831/04A patent/RU2243230C2/ru not_active IP Right Cessation
- 2000-01-12 EP EP00904899A patent/EP1144427B1/en not_active Expired - Lifetime
- 2000-01-12 JP JP2000593622A patent/JP4568433B2/ja not_active Expired - Fee Related
-
2001
- 2001-01-12 US US09/889,284 patent/US6455576B1/en not_active Expired - Lifetime
- 2001-06-28 IL IL144044A patent/IL144044A/en not_active IP Right Cessation
- 2001-07-12 ZA ZA200105748A patent/ZA200105748B/en unknown
- 2001-07-16 NO NO20013517A patent/NO318982B1/no not_active IP Right Cessation
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