HU229228B1 - Macrolides with anti-inflammatory activity - Google Patents

Macrolides with anti-inflammatory activity Download PDF

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Publication number
HU229228B1
HU229228B1 HU0105105A HUP0105105A HU229228B1 HU 229228 B1 HU229228 B1 HU 229228B1 HU 0105105 A HU0105105 A HU 0105105A HU P0105105 A HUP0105105 A HU P0105105A HU 229228 B1 HU229228 B1 HU 229228B1
Authority
HU
Hungary
Prior art keywords
group
hydrogen
formula
groups
carbon atoms
Prior art date
Application number
HU0105105A
Other languages
English (en)
Hungarian (hu)
Inventor
Franco Pellacini
Daniela Botta
Stefano Romagnano
Ermanno Moriggi
Lorenzo Pradella
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of HUP0105105A2 publication Critical patent/HUP0105105A2/hu
Publication of HUP0105105A3 publication Critical patent/HUP0105105A3/hu
Publication of HU229228B1 publication Critical patent/HU229228B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
HU0105105A 1999-01-15 2000-01-12 Macrolides with anti-inflammatory activity HU229228B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI000061A IT1306205B1 (it) 1999-01-15 1999-01-15 Macrolidi ad attivita' antiinfiammatoria.
PCT/EP2000/000163 WO2000042055A2 (en) 1999-01-15 2000-01-12 Macrolides with anti-inflammatory activity

Publications (3)

Publication Number Publication Date
HUP0105105A2 HUP0105105A2 (hu) 2002-04-29
HUP0105105A3 HUP0105105A3 (en) 2003-05-28
HU229228B1 true HU229228B1 (en) 2013-09-30

Family

ID=11381492

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0105105A HU229228B1 (en) 1999-01-15 2000-01-12 Macrolides with anti-inflammatory activity

Country Status (19)

Country Link
US (1) US6455576B1 (enExample)
EP (1) EP1144427B1 (enExample)
JP (1) JP4568433B2 (enExample)
CN (1) CN1151165C (enExample)
AT (1) ATE308552T1 (enExample)
AU (1) AU769006B2 (enExample)
BR (1) BR0007514A (enExample)
CA (1) CA2368400C (enExample)
DE (1) DE60023647T2 (enExample)
ES (1) ES2251966T3 (enExample)
HU (1) HU229228B1 (enExample)
IL (2) IL144044A0 (enExample)
IT (1) IT1306205B1 (enExample)
MX (1) MXPA01007164A (enExample)
NO (1) NO318982B1 (enExample)
RU (1) RU2243230C2 (enExample)
SK (1) SK286772B6 (enExample)
WO (1) WO2000042055A2 (enExample)
ZA (1) ZA200105748B (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20010018A2 (en) 2001-01-09 2002-12-31 Pliva D D Novel anti-inflammatory compounds
NZ537717A (en) 2002-07-08 2006-04-28 Pliva Istrazivacki Inst D New compounds, compositions and methods for treatment of inflammatory diseases and conditions
PL374646A1 (en) * 2002-07-08 2005-10-31 Pliva-Istrazivacki Institutt D.O.O. Novel nonsteroidal anti-inflammatory substances, compositions and methods for their use
DE60327341D1 (de) * 2002-07-08 2009-06-04 Glaxosmithkline Zagreb Hybridmoleküle von makroliden mit steroidalen/nicht-steroidalen antientzündlich aktiven molekülen
ITMI20021726A1 (it) * 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
AR043050A1 (es) 2002-09-26 2005-07-13 Rib X Pharmaceuticals Inc Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos
ITMI20022292A1 (it) * 2002-10-29 2004-04-30 Zambon Spa 9a-azalidi ad attivita' antiinfiammatoria.
CA2521462A1 (en) 2003-04-17 2004-10-28 Sandoz Ag Derivatives of azithromycin
HRP20030324A2 (en) 2003-04-24 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. Compounds of antiinflammatory effect
ITMI20040124A1 (it) * 2004-01-29 2004-04-29 Zambon Spa Macrolidi ad attivita' antiinfiammatoria
WO2006130128A2 (en) * 2004-02-18 2006-12-07 Chiron Corporation Methods of identifying anti-inflammatory macrolides
JP5383037B2 (ja) 2004-02-27 2014-01-08 リブ−エックス ファーマシューティカルズ，インコーポレイテッド 大環状化合物およびそれらを製造し使用する方法
WO2006035301A2 (en) * 2004-09-27 2006-04-06 Ranbaxy Laboratories Limited Erythromycin a derivatives as antibacterial agents
WO2006046123A2 (en) 2004-10-27 2006-05-04 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Conjugates with anti-inflammatory activity
US20080249034A1 (en) * 2005-03-21 2008-10-09 Zambon S.P.A. Use of Macrolides for Treating Intestinal Inflammation
US7582611B2 (en) * 2005-05-24 2009-09-01 Pfizer Inc. Motilide compounds
WO2011090940A1 (en) 2010-01-19 2011-07-28 Cerulean Pharma Inc. Cyclodextrin-based polymers for therapeutic delivery
RU2455309C2 (ru) * 2010-07-20 2012-07-10 Открытое Акционерное Общество "Татхимфармпрепараты" Способ получения аморфной формы рокситромицина
GB201608236D0 (en) 2016-05-11 2016-06-22 Fidelta D O O Seco macrolide compounds
US11771677B2 (en) 2020-03-12 2023-10-03 Zoetis Services Llc Immunomodulating urea azalides
US20230131943A1 (en) 2020-03-24 2023-04-27 Burnet Micheal W Anti-infective and anti-viral compounds and compositions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3928387A (en) * 1974-02-04 1975-12-23 Hoffmann La Roche Antibiotic 1745A/X and methods for the production thereof
IT1189285B (it) * 1982-05-28 1988-02-04 Nuovo Consor Sanitar Nazionale Sali dell'antibiotico eritromicina e del suo estere propionico con acidi ad attivita' terapeutica coadiuvante
EP0254534A3 (en) * 1986-07-24 1991-04-17 William S. Robinson Erythromycin derivatives and compositions and use for inhibiting virus replication and disease
FR2697524B1 (fr) * 1992-11-05 1994-12-23 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
IT1276901B1 (it) * 1994-12-13 1997-11-03 Zambon Spa Derivati dell'eritromicina a 9-0-ossina dotati di attivita' antibiotica
KR19980701895A (ko) * 1995-03-08 1998-06-25 이라우치지마 가즈다카 면역관련병 처치제 및 그의 탐색 방법

Also Published As

Publication number Publication date
ATE308552T1 (de) 2005-11-15
WO2000042055A3 (en) 2001-09-07
HUP0105105A2 (hu) 2002-04-29
JP2002534531A (ja) 2002-10-15
ES2251966T3 (es) 2006-05-16
SK286772B6 (sk) 2009-05-07
MXPA01007164A (es) 2002-03-27
BR0007514A (pt) 2001-11-20
EP1144427B1 (en) 2005-11-02
EP1144427A2 (en) 2001-10-17
CA2368400A1 (en) 2000-07-20
JP4568433B2 (ja) 2010-10-27
ZA200105748B (en) 2002-10-14
DE60023647D1 (de) 2005-12-08
IT1306205B1 (it) 2001-05-30
AU769006B2 (en) 2004-01-15
CN1336932A (zh) 2002-02-20
US6455576B1 (en) 2002-09-24
DE60023647T2 (de) 2006-08-10
EP1144427A3 (en) 2002-08-28
RU2243230C2 (ru) 2004-12-27
IL144044A0 (en) 2002-04-21
ITMI990061A1 (it) 2000-07-15
SK9812001A3 (en) 2002-01-07
NO318982B1 (no) 2005-05-30
IL144044A (en) 2006-12-31
WO2000042055A2 (en) 2000-07-20
NO20013517L (no) 2001-07-16
CN1151165C (zh) 2004-05-26
CA2368400C (en) 2007-06-05
AU2663600A (en) 2000-08-01
NO20013517D0 (no) 2001-07-16
HUP0105105A3 (en) 2003-05-28

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Legal Events

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MM4A Lapse of definitive patent protection due to non-payment of fees