ATE308552T1 - Makrolide mit entzündungshemmender wirkung - Google Patents

Makrolide mit entzündungshemmender wirkung

Info

Publication number
ATE308552T1
ATE308552T1 AT00904899T AT00904899T ATE308552T1 AT E308552 T1 ATE308552 T1 AT E308552T1 AT 00904899 T AT00904899 T AT 00904899T AT 00904899 T AT00904899 T AT 00904899T AT E308552 T1 ATE308552 T1 AT E308552T1
Authority
AT
Austria
Prior art keywords
macrolids
inflammatory effect
oxyimino
macrolides
endowed
Prior art date
Application number
AT00904899T
Other languages
English (en)
Inventor
Franco Pellacini
Daniela Botta
Stefano Romagnano
Ermanno Moriggi
Lorenzo Pradella
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Application granted granted Critical
Publication of ATE308552T1 publication Critical patent/ATE308552T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
AT00904899T 1999-01-15 2000-01-12 Makrolide mit entzündungshemmender wirkung ATE308552T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI000061A IT1306205B1 (it) 1999-01-15 1999-01-15 Macrolidi ad attivita' antiinfiammatoria.
PCT/EP2000/000163 WO2000042055A2 (en) 1999-01-15 2000-01-12 Macrolides with anti-inflammatory activity

Publications (1)

Publication Number Publication Date
ATE308552T1 true ATE308552T1 (de) 2005-11-15

Family

ID=11381492

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00904899T ATE308552T1 (de) 1999-01-15 2000-01-12 Makrolide mit entzündungshemmender wirkung

Country Status (19)

Country Link
US (1) US6455576B1 (de)
EP (1) EP1144427B1 (de)
JP (1) JP4568433B2 (de)
CN (1) CN1151165C (de)
AT (1) ATE308552T1 (de)
AU (1) AU769006B2 (de)
BR (1) BR0007514A (de)
CA (1) CA2368400C (de)
DE (1) DE60023647T2 (de)
ES (1) ES2251966T3 (de)
HU (1) HU229228B1 (de)
IL (2) IL144044A0 (de)
IT (1) IT1306205B1 (de)
MX (1) MXPA01007164A (de)
NO (1) NO318982B1 (de)
RU (1) RU2243230C2 (de)
SK (1) SK286772B6 (de)
WO (1) WO2000042055A2 (de)
ZA (1) ZA200105748B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20010018A2 (en) 2001-01-09 2002-12-31 Pliva D D Novel anti-inflammatory compounds
ATE429441T1 (de) 2002-07-08 2009-05-15 Glaxosmithkline Zagreb Hybridmoleküle von makroliden mit steroidalen/nicht-steroidalen antientzündlich aktiven molekülen
RS20050007A (sr) * 2002-07-08 2007-09-21 Glaxo Smith Kline Istraživački Centar Zagreb D.O.O., NOVE NESTEROIDNE-ANTI- INFLAMATORNE SUPSTANCE, KOMPOZICIJE I POSTUPCI ZA NjIHOVU UPOTREBU
WO2004005310A2 (en) 2002-07-08 2004-01-15 Pliva-Istrazivacki Institut D.O.O. New compounds, compositions and methods for treatment of inflammatory diseases and conditions
ITMI20021726A1 (it) 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
TW200420573A (en) 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
ITMI20022292A1 (it) 2002-10-29 2004-04-30 Zambon Spa 9a-azalidi ad attivita' antiinfiammatoria.
EP1622922A2 (de) 2003-04-17 2006-02-08 Sandoz AG Azithromycin-derivate
HRP20030324A2 (en) 2003-04-24 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. Compounds of antiinflammatory effect
ITMI20040124A1 (it) * 2004-01-29 2004-04-29 Zambon Spa Macrolidi ad attivita' antiinfiammatoria
WO2006130128A2 (en) * 2004-02-18 2006-12-07 Chiron Corporation Methods of identifying anti-inflammatory macrolides
US8202843B2 (en) 2004-02-27 2012-06-19 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same
EP1812455A2 (de) * 2004-09-27 2007-08-01 Ranbaxy Laboratories Limited Erythromycin-a-derivate als antibakterielle mittel
ES2337915T3 (es) 2004-10-27 2010-04-30 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Conjugados con adtividad antiinflamatoria.
US20080249034A1 (en) * 2005-03-21 2008-10-09 Zambon S.P.A. Use of Macrolides for Treating Intestinal Inflammation
US7582611B2 (en) * 2005-05-24 2009-09-01 Pfizer Inc. Motilide compounds
WO2011090940A1 (en) 2010-01-19 2011-07-28 Cerulean Pharma Inc. Cyclodextrin-based polymers for therapeutic delivery
RU2455309C2 (ru) * 2010-07-20 2012-07-10 Открытое Акционерное Общество "Татхимфармпрепараты" Способ получения аморфной формы рокситромицина
GB201608236D0 (en) 2016-05-11 2016-06-22 Fidelta D O O Seco macrolide compounds
US11771677B2 (en) 2020-03-12 2023-10-03 Zoetis Services Llc Immunomodulating urea azalides
WO2021195126A1 (en) 2020-03-24 2021-09-30 Burnet Michael W Anti-infective and anti-viral compounds and compositions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3928387A (en) * 1974-02-04 1975-12-23 Hoffmann La Roche Antibiotic 1745A/X and methods for the production thereof
IT1189285B (it) * 1982-05-28 1988-02-04 Nuovo Consor Sanitar Nazionale Sali dell'antibiotico eritromicina e del suo estere propionico con acidi ad attivita' terapeutica coadiuvante
EP0254534A3 (de) * 1986-07-24 1991-04-17 William S. Robinson Erythromycin-Derivate und Zusammensetzungen und ihre Verwendung, um Virusreplikation und Krankheiten zu Inhibieren
FR2697524B1 (fr) * 1992-11-05 1994-12-23 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
IT1276901B1 (it) * 1994-12-13 1997-11-03 Zambon Spa Derivati dell'eritromicina a 9-0-ossina dotati di attivita' antibiotica
WO1996027391A1 (en) * 1995-03-08 1996-09-12 Environmental Research Institute, Inc. Drug for treating immunity-related diseases and method of searching for the same

Also Published As

Publication number Publication date
CN1151165C (zh) 2004-05-26
WO2000042055A3 (en) 2001-09-07
BR0007514A (pt) 2001-11-20
DE60023647D1 (de) 2005-12-08
JP2002534531A (ja) 2002-10-15
CA2368400A1 (en) 2000-07-20
EP1144427A2 (de) 2001-10-17
CN1336932A (zh) 2002-02-20
AU2663600A (en) 2000-08-01
IL144044A (en) 2006-12-31
IL144044A0 (en) 2002-04-21
US6455576B1 (en) 2002-09-24
AU769006B2 (en) 2004-01-15
NO20013517D0 (no) 2001-07-16
RU2243230C2 (ru) 2004-12-27
CA2368400C (en) 2007-06-05
DE60023647T2 (de) 2006-08-10
ES2251966T3 (es) 2006-05-16
HU229228B1 (en) 2013-09-30
HUP0105105A2 (hu) 2002-04-29
HUP0105105A3 (en) 2003-05-28
NO318982B1 (no) 2005-05-30
MXPA01007164A (es) 2002-03-27
JP4568433B2 (ja) 2010-10-27
SK9812001A3 (en) 2002-01-07
EP1144427B1 (de) 2005-11-02
ITMI990061A1 (it) 2000-07-15
ZA200105748B (en) 2002-10-14
NO20013517L (no) 2001-07-16
WO2000042055A2 (en) 2000-07-20
SK286772B6 (sk) 2009-05-07
IT1306205B1 (it) 2001-05-30
EP1144427A3 (de) 2002-08-28

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