JP2002524524A5 - - Google Patents
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- Publication number
- JP2002524524A5 JP2002524524A5 JP2000569824A JP2000569824A JP2002524524A5 JP 2002524524 A5 JP2002524524 A5 JP 2002524524A5 JP 2000569824 A JP2000569824 A JP 2000569824A JP 2000569824 A JP2000569824 A JP 2000569824A JP 2002524524 A5 JP2002524524 A5 JP 2002524524A5
- Authority
- JP
- Japan
- Prior art keywords
- dendrimer
- terminated
- acid
- pharmaceutical composition
- terminal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000000412 dendrimer Substances 0.000 description 54
- 229920000736 dendritic polymer Polymers 0.000 description 54
- 239000008194 pharmaceutical composition Substances 0.000 description 15
- 239000002253 acid Substances 0.000 description 8
- KXDAEFPNCMNJSK-UHFFFAOYSA-N Benzamide Chemical compound NC(=O)C1=CC=CC=C1 KXDAEFPNCMNJSK-UHFFFAOYSA-N 0.000 description 6
- 125000000217 alkyl group Chemical group 0.000 description 6
- 150000001875 compounds Chemical class 0.000 description 6
- -1 alkyl sulfonic acid Chemical compound 0.000 description 5
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 4
- 150000001450 anions Chemical class 0.000 description 4
- 125000003118 aryl group Chemical group 0.000 description 4
- 150000001768 cations Chemical class 0.000 description 4
- 229910052739 hydrogen Inorganic materials 0.000 description 4
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 3
- UMGDCJDMYOKAJW-UHFFFAOYSA-N aminothiocarboxamide Chemical group NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 description 3
- 230000001580 bacterial effect Effects 0.000 description 3
- 230000002538 fungal effect Effects 0.000 description 3
- 125000000896 monocarboxylic acid group Chemical group 0.000 description 3
- UHBGYFCCKRAEHA-UHFFFAOYSA-N P-toluamide Chemical compound CC1=CC=C(C(N)=O)C=C1 UHBGYFCCKRAEHA-UHFFFAOYSA-N 0.000 description 2
- ABLZXFCXXLZCGV-UHFFFAOYSA-N Phosphorous acid Chemical compound OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical group NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- OOEZTTCJYIGGPQ-UHFFFAOYSA-N [4-(carbamothioylamino)phenyl] dihydrogen phosphate Chemical compound NC(=S)NC1=CC=C(OP(O)(O)=O)C=C1 OOEZTTCJYIGGPQ-UHFFFAOYSA-N 0.000 description 2
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 2
- 125000003710 aryl alkyl group Chemical group 0.000 description 2
- SQVRNKJHWKZAKO-UHFFFAOYSA-N beta-N-Acetyl-D-neuraminic acid Natural products CC(=O)NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO SQVRNKJHWKZAKO-UHFFFAOYSA-N 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- BQINXKOTJQCISL-GRCPKETISA-N keto-neuraminic acid Chemical compound OC(=O)C(=O)C[C@H](O)[C@@H](N)[C@@H](O)[C@H](O)[C@H](O)CO BQINXKOTJQCISL-GRCPKETISA-N 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000003071 parasitic effect Effects 0.000 description 2
- 229920000962 poly(amidoamine) Polymers 0.000 description 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 2
- 230000000069 prophylactic effect Effects 0.000 description 2
- SQVRNKJHWKZAKO-OQPLDHBCSA-N sialic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)OC1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-OQPLDHBCSA-N 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- MDAXKAUIABOHTD-UHFFFAOYSA-N 1,4,8,11-tetraazacyclotetradecane Chemical compound C1CNCCNCCCNCCNC1 MDAXKAUIABOHTD-UHFFFAOYSA-N 0.000 description 1
- DVZWMDIRFMBWSC-UHFFFAOYSA-N 2-[(4-amino-4-oxobutanoyl)amino]ethanesulfonic acid Chemical compound NC(=O)CCC(=O)NCCS(O)(=O)=O DVZWMDIRFMBWSC-UHFFFAOYSA-N 0.000 description 1
- KHMVPPUPOGJSFK-UHFFFAOYSA-N 4-(carbamothioylamino)benzenesulfonic acid Chemical compound NC(=S)NC1=CC=C(S(O)(=O)=O)C=C1 KHMVPPUPOGJSFK-UHFFFAOYSA-N 0.000 description 1
- DZQZJJXVAMIPNR-UHFFFAOYSA-N 4-(carbamothioylamino)naphthalene-1-sulfonic acid Chemical compound C1=CC=C2C(NC(=S)N)=CC=C(S(O)(=O)=O)C2=C1 DZQZJJXVAMIPNR-UHFFFAOYSA-N 0.000 description 1
- MFBPZROATHHERV-UHFFFAOYSA-N 4-(carbamothioylamino)naphthalene-2,7-disulfonic acid Chemical compound OS(=O)(=O)C1=CC=C2C(NC(=S)N)=CC(S(O)(=O)=O)=CC2=C1 MFBPZROATHHERV-UHFFFAOYSA-N 0.000 description 1
- XJJDJRSMXUUIKJ-UHFFFAOYSA-N 4-(carbamoylamino)benzenesulfonic acid Chemical compound NC(=O)NC1=CC=C(S(O)(=O)=O)C=C1 XJJDJRSMXUUIKJ-UHFFFAOYSA-N 0.000 description 1
- NILHACLJODBATD-UHFFFAOYSA-N 4-(propanoylamino)benzenesulfonic acid Chemical compound CCC(=O)NC1=CC=C(S(O)(=O)=O)C=C1 NILHACLJODBATD-UHFFFAOYSA-N 0.000 description 1
- BCFOOQRXUXKJCL-UHFFFAOYSA-N 4-amino-4-oxo-2-sulfobutanoic acid Chemical compound NC(=O)CC(C(O)=O)S(O)(=O)=O BCFOOQRXUXKJCL-UHFFFAOYSA-N 0.000 description 1
- ALYNCZNDIQEVRV-UHFFFAOYSA-N 4-aminobenzoic acid Chemical compound NC1=CC=C(C(O)=O)C=C1 ALYNCZNDIQEVRV-UHFFFAOYSA-N 0.000 description 1
- FNMPWSYBWQWZSF-UHFFFAOYSA-N 4-carbamoylbenzenesulfonic acid Chemical compound NC(=O)C1=CC=C(S(O)(=O)=O)C=C1 FNMPWSYBWQWZSF-UHFFFAOYSA-N 0.000 description 1
- VHHHYFRIANJFAT-UHFFFAOYSA-N 5-(carbamothioylamino)benzene-1,3-dicarboxylic acid Chemical compound NC(=S)NC1=CC(C(O)=O)=CC(C(O)=O)=C1 VHHHYFRIANJFAT-UHFFFAOYSA-N 0.000 description 1
- KIQNQOQMGFSEMM-UHFFFAOYSA-N 5-(carbamothioylamino)benzene-1,3-disulfonic acid Chemical compound NC(=S)NC1=CC(S(O)(=O)=O)=CC(S(O)(=O)=O)=C1 KIQNQOQMGFSEMM-UHFFFAOYSA-N 0.000 description 1
- KBZFDRWPMZESDI-UHFFFAOYSA-N 5-aminobenzene-1,3-dicarboxylic acid Chemical compound NC1=CC(C(O)=O)=CC(C(O)=O)=C1 KBZFDRWPMZESDI-UHFFFAOYSA-N 0.000 description 1
- NDWQMRYDEZSGEF-UHFFFAOYSA-N 8-(carbamothioylamino)naphthalene-1,3,6-trisulfonic acid Chemical compound OS(=O)(=O)C1=CC(S(O)(=O)=O)=C2C(NC(=S)N)=CC(S(O)(=O)=O)=CC2=C1 NDWQMRYDEZSGEF-UHFFFAOYSA-N 0.000 description 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical group N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 description 1
- ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 108010039918 Polylysine Proteins 0.000 description 1
- MSMXAJVUGSDTNQ-UHFFFAOYSA-N [4-(carbamothioylamino)-7-phosphononaphthalen-1-yl]phosphonic acid Chemical compound OP(=O)(O)C1=CC=C2C(NC(=S)N)=CC=C(P(O)(O)=O)C2=C1 MSMXAJVUGSDTNQ-UHFFFAOYSA-N 0.000 description 1
- JDFHYYZTUNBHCA-UHFFFAOYSA-N [4-(carbamothioylamino)phenyl]methylphosphonic acid Chemical compound NC(=S)NC1=CC=C(CP(O)(O)=O)C=C1 JDFHYYZTUNBHCA-UHFFFAOYSA-N 0.000 description 1
- GDBQRUMLUQFAPB-UHFFFAOYSA-N [4-(carbamothioylamino)phenyl]phosphonic acid Chemical compound NC(=S)NC1=CC=C(P(O)(O)=O)C=C1 GDBQRUMLUQFAPB-UHFFFAOYSA-N 0.000 description 1
- JRROFPKPQONCSD-UHFFFAOYSA-N [4-[carbamothioyl(ethyl)amino]phenyl]methylphosphonic acid Chemical compound CCN(C(N)=S)C1=CC=C(CP(O)(O)=O)C=C1 JRROFPKPQONCSD-UHFFFAOYSA-N 0.000 description 1
- 125000000738 acetamido group Chemical group [H]C([H])([H])C(=O)N([H])[*] 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 150000001408 amides Chemical group 0.000 description 1
- 125000000909 amidinium group Chemical group 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 229910052796 boron Inorganic materials 0.000 description 1
- ZADPBFCGQRWHPN-UHFFFAOYSA-N boronic acid Chemical compound OBO ZADPBFCGQRWHPN-UHFFFAOYSA-N 0.000 description 1
- DNSISZSEWVHGLH-UHFFFAOYSA-N butanamide Chemical compound CCCC(N)=O DNSISZSEWVHGLH-UHFFFAOYSA-N 0.000 description 1
- UKYZWASSXSSTCI-UHFFFAOYSA-N c1cc[nH+]cc1.CCCCCCCCCCCCC([NH-])=O Chemical compound c1cc[nH+]cc1.CCCCCCCCCCCCC([NH-])=O UKYZWASSXSSTCI-UHFFFAOYSA-N 0.000 description 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 description 1
- 125000002091 cationic group Chemical group 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- MGHPNCMVUAKAIE-UHFFFAOYSA-N diphenylmethanamine Chemical group C=1C=CC=CC=1C(N)C1=CC=CC=C1 MGHPNCMVUAKAIE-UHFFFAOYSA-N 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 125000003916 ethylene diamine group Chemical group 0.000 description 1
- GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical compound O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 description 1
- ZRALSGWEFCBTJO-UHFFFAOYSA-O guanidinium Chemical compound NC(N)=[NH2+] ZRALSGWEFCBTJO-UHFFFAOYSA-O 0.000 description 1
- 125000002795 guanidino group Chemical group C(N)(=N)N* 0.000 description 1
- 125000000623 heterocyclic group Chemical group 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 229920000831 ionic polymer Polymers 0.000 description 1
- 125000005647 linker group Chemical group 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- CERZMXAJYMMUDR-UHFFFAOYSA-N neuraminic acid Natural products NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO CERZMXAJYMMUDR-UHFFFAOYSA-N 0.000 description 1
- LTHCSWBWNVGEFE-UHFFFAOYSA-N octanamide Chemical compound CCCCCCCC(N)=O LTHCSWBWNVGEFE-UHFFFAOYSA-N 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 229920000333 poly(propyleneimine) Polymers 0.000 description 1
- 229920000656 polylysine Polymers 0.000 description 1
- JUJWROOIHBZHMG-UHFFFAOYSA-O pyridinium Chemical compound C1=CC=[NH+]C=C1 JUJWROOIHBZHMG-UHFFFAOYSA-O 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 125000003396 thiol group Chemical group [H]S* 0.000 description 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU5842 | 1998-09-14 | ||
| AUPP5842A AUPP584298A0 (en) | 1998-09-14 | 1998-09-14 | Antimicrobial and antiparasitic agents |
| AUPP5842 | 1998-09-14 | ||
| PCT/AU1999/000763 WO2000015240A1 (en) | 1998-09-14 | 1999-09-13 | Anionic or cationic dendrimer antimicrobial or antiparasitic compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002524524A JP2002524524A (ja) | 2002-08-06 |
| JP2002524524A5 true JP2002524524A5 (enExample) | 2006-11-09 |
| JP4979848B2 JP4979848B2 (ja) | 2012-07-18 |
Family
ID=3810064
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000569824A Expired - Lifetime JP4979848B2 (ja) | 1998-09-14 | 1999-09-13 | 陰イオン性または陽イオン性デンドリマー抗微生物または抗寄生虫組成物 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6464971B1 (enExample) |
| EP (1) | EP1113806B1 (enExample) |
| JP (1) | JP4979848B2 (enExample) |
| KR (1) | KR100720905B1 (enExample) |
| CN (2) | CN1323214A (enExample) |
| AT (1) | ATE372123T1 (enExample) |
| AU (1) | AUPP584298A0 (enExample) |
| BR (1) | BR9913712A (enExample) |
| CA (1) | CA2343113C (enExample) |
| DE (1) | DE69937059T2 (enExample) |
| NZ (1) | NZ510289A (enExample) |
| WO (1) | WO2000015240A1 (enExample) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7572459B2 (en) * | 1998-09-14 | 2009-08-11 | Starpharma Pty Ltd. | Anionic or cationic dendrimer antimicrobial or antiparasitic compositions |
| KR100413532B1 (ko) * | 2001-02-14 | 2003-12-31 | 학교법인 포항공과대학교 | 폴리아민이 말단에 치환된 덴드리머 및 그 제조방법 |
| AUPR412801A0 (en) | 2001-03-30 | 2001-05-03 | Starpharma Limited | Agent for the prevention and treatment of sexually transmitted disease s - I |
| AUPR412901A0 (en) * | 2001-03-30 | 2001-05-03 | Starpharma Limited | Agents for the prevention and treatment of sexually transmitted disease s - II |
| EP1461084A2 (en) * | 2001-12-11 | 2004-09-29 | The Board Of Trustees Of The Leland Stanford Junior University | Guanidinium transport reagents and conjugates |
| WO2004019993A1 (en) * | 2002-08-30 | 2004-03-11 | Ramot At Tel Aviv University Ltd. | Self-immolative dendrimers releasing many active moieties upon a single activating event |
| US20040234496A1 (en) * | 2003-02-06 | 2004-11-25 | Stockel Richard F. | Biocidal compositions |
| US7074459B2 (en) * | 2003-05-23 | 2006-07-11 | Stockel Richard F | Method for preserving wood |
| FR2862650B1 (fr) * | 2003-11-24 | 2007-04-20 | Rhodia Cons Spec Ltd | Nouveaux dendrimeres a terminaisons monophosphoniques, leur procede de preparation et leur utilisation |
| FR2862651B1 (fr) * | 2003-11-24 | 2006-03-31 | Rhodia Cons Spec Ltd | Nouveaux dendrimeres a terminaisons bisphosphoniques et derives, leur procede de preparation et leur utilisation |
| CN1296711C (zh) * | 2004-05-14 | 2007-01-24 | 沈阳迈迪生物医学技术有限公司 | 乳腺癌的Her－2免疫组织化学诊断试剂盒 |
| JP4553354B2 (ja) * | 2004-10-04 | 2010-09-29 | 正隆 井原 | 抗トリパノソーマ剤 |
| US8790672B2 (en) * | 2005-02-22 | 2014-07-29 | Nina M. Lamba-Kohli | Generation of antimicrobial surfaces using dendrimer biocides |
| US20060269480A1 (en) * | 2005-05-31 | 2006-11-30 | Ramot At Tel Aviv University Ltd. | Multi-triggered self-immolative dendritic compounds |
| CA2612211A1 (en) * | 2005-07-08 | 2007-01-18 | Janssen Pharmaceutica N.V. | Modified poly(propylene-imine) dendrimers and their use as transfection agents for anionic bioactive factors |
| KR101451991B1 (ko) | 2005-10-18 | 2014-10-22 | 스타파마 피티와이 리미티드 | 살미생물성 덴드리머 조성물 전달 시스템 |
| WO2007045010A1 (en) * | 2005-10-21 | 2007-04-26 | Starpharma Pty Limited | Inhibitory compounds |
| CA2647325C (en) * | 2005-12-12 | 2015-03-24 | Allaccem, Inc. | Methods and systems for preparing antimicrobial bridged polycyclic compounds |
| JP5989294B2 (ja) | 2006-01-20 | 2016-09-07 | スターファーマ・プロプライエタリー・リミテッドＳｔａｒｐｈａｒｍａ Ｐｔｙ Ｌｔｄ | 修飾高分子 |
| ES2558875T3 (es) | 2006-03-22 | 2016-02-09 | Starpharma Pty Limited | Composición anticonceptiva |
| AU2008218275B2 (en) | 2007-02-21 | 2013-06-20 | Allaccem, Incorporated | Bridged polycyclic compound based compositions for the inhibition and amelioration of disease |
| US20080282480A1 (en) * | 2007-05-15 | 2008-11-20 | The Hong Kong Polytechnic University | Multifunction Finishing Liquids Containing Dendrimers and the Application of the Liquids in Textile Finishing |
| US20090001802A1 (en) * | 2007-05-21 | 2009-01-01 | Diallo Mamadou S | Extraction of Actinides From Mixtures and Ores Using Dendritic Macromolecules |
| US8188068B2 (en) * | 2007-08-10 | 2012-05-29 | Allaccem, Inc. | Bridged polycyclic compound based compositions for coating oral surfaces in pets |
| US8153618B2 (en) * | 2007-08-10 | 2012-04-10 | Allaccem, Inc. | Bridged polycyclic compound based compositions for topical applications for pets |
| US8153617B2 (en) * | 2007-08-10 | 2012-04-10 | Allaccem, Inc. | Bridged polycyclic compound based compositions for coating oral surfaces in humans |
| US20090074833A1 (en) * | 2007-08-17 | 2009-03-19 | Whiteford Jeffery A | Bridged polycyclic compound based compositions for controlling bone resorption |
| US20100004218A1 (en) * | 2008-06-20 | 2010-01-07 | Whiteford Jeffery A | Bridged polycyclic compound based compositions for renal therapy |
| US20100016270A1 (en) * | 2008-06-20 | 2010-01-21 | Whiteford Jeffery A | Bridged polycyclic compound based compositions for controlling cholesterol levels |
| US20100008864A1 (en) * | 2008-07-10 | 2010-01-14 | Andreas Meijer | Aromatic multimers |
| WO2010040117A2 (en) * | 2008-10-03 | 2010-04-08 | California Institute Of Technology | Extraction of anions from solutions and mixtures using hyperbranched macromolecules |
| US9815712B2 (en) | 2008-10-03 | 2017-11-14 | California Institute Of Technology | High capacity perchlorate-selective resins from hyperbranched macromolecules |
| WO2011001657A1 (ja) | 2009-07-01 | 2011-01-06 | 独立行政法人科学技術振興機構 | ポリイオンデンドリマー、及びそれよりなるハイドロゲル |
| JP5212656B2 (ja) * | 2009-09-02 | 2013-06-19 | 日産化学工業株式会社 | イソチオシアナト化合物の製造方法 |
| WO2011084719A2 (en) | 2009-12-17 | 2011-07-14 | California Institute Of Technology | Soluble anion exchangers from hyperbranched macromolecules |
| US9814239B2 (en) * | 2010-06-30 | 2017-11-14 | Huiwen Liu | Antimicrobial complexes |
| RU2478106C2 (ru) * | 2010-11-25 | 2013-03-27 | Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Казанский (Приволжский) Федеральный Университет" (ФГАОУ ВПО КФУ) | СОЕДИНЕНИЯ НА ОСНОВЕ КОМПЛЕКСОВ ГИПЕРРАЗВЕТВЛЕННЫХ ПОЛИМЕРОВ Boltorn H, ОБЛАДАЮЩИЕ АНТИКАНДИДОЗНОЙ АКТИВНОСТЬЮ, И СПОСОБ ИХ ПОЛУЧЕНИЯ |
| US9102602B2 (en) | 2010-11-29 | 2015-08-11 | Nissan Chemical Industries, Ltd. | Method for producing isothiocyanate compound |
| JP6057987B2 (ja) * | 2011-05-16 | 2017-01-11 | スターファーマ・ピーティーワイ・リミテッド | 細菌性膣炎の治療または予防の方法 |
| WO2013074526A2 (en) | 2011-11-15 | 2013-05-23 | Byocoat Enterprises, Inc. | Antimicrobial compositions and methods of use thereof |
| EP2895161B1 (en) | 2012-09-13 | 2017-05-03 | Starpharma Pty Limited | Method of treatment or prophylaxis of infections of the eye |
| US9662372B2 (en) * | 2013-02-20 | 2017-05-30 | Biolog, Inc. | Compositions and methods to inactivate and/or reduce production of microbial toxins |
| RU2644554C2 (ru) * | 2013-03-15 | 2018-02-13 | Джензим Корпорейшн | Амин-функциональные полиамиды |
| GB201405660D0 (en) * | 2014-03-28 | 2014-05-14 | Gama Healthcare Ltd | A liquid disinfecting composition |
| CN103999853B (zh) * | 2014-06-11 | 2015-07-22 | 中国农业大学 | 荧光树枝状纳米大分子在制备药物载体中的应用 |
| US9854806B2 (en) | 2015-05-19 | 2018-01-02 | International Business Machines Corporation | Antimicrobial guanidinium and thiouronium functionalized polymers |
| JP7089479B2 (ja) * | 2016-04-14 | 2022-06-22 | ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド | 抗菌性ポリアミド又はオクテニジン保存剤を含むマルチドーズ組成物 |
| US11154589B2 (en) | 2016-11-02 | 2021-10-26 | The University Of Melbourne | Antimicrobial composition combinations comprising star shaped peptide polymers |
| WO2018081845A1 (en) | 2016-11-02 | 2018-05-11 | The University Of Melbourne | Antibacterial compositions and methods |
| US10953039B2 (en) | 2018-09-27 | 2021-03-23 | International Business Machines Corporation | Utilizing polymers and antibiotics to enhance antimicrobial activity and inhibit antibiotic resistance |
| CN110041523B (zh) * | 2019-04-15 | 2021-04-30 | 同济大学 | 低代树枝状聚赖氨酸类抗菌肽及其制备方法 |
| CN114053392B (zh) * | 2020-07-30 | 2024-06-21 | 广州朗圣药业有限公司 | 新型化合物在制备预防和/或治疗hpv感染的药物中的应用 |
Family Cites Families (7)
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|---|---|---|---|---|
| AUPM623994A0 (en) * | 1994-06-15 | 1994-07-07 | Biomolecular Research Institute Limited | Antiviral dendrimers |
| US5736533A (en) * | 1995-06-07 | 1998-04-07 | Neose Technologies, Inc. | Bacterial inhibition with an oligosaccharide compound |
| US5658574A (en) | 1995-10-13 | 1997-08-19 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Cleansing compositions with dendrimers as mildness agents |
| DE19624705A1 (de) | 1996-06-20 | 1998-01-08 | Deutsches Krebsforsch | Dendrimere auf Saccharid-Basis |
| AUPO104496A0 (en) * | 1996-07-17 | 1996-08-08 | Biomolecular Research Institute Limited | Angiogenic inhibitory compounds |
| AU5610198A (en) * | 1996-12-19 | 1998-07-15 | Penn State Research Foundation, The | Compounds and methods for treating and preventing bacterial and viral disease |
| AUPP584398A0 (en) * | 1998-09-14 | 1998-10-08 | Starpharma Limited | Inhibition of toxic materials or substances |
-
1998
- 1998-09-14 AU AUPP5842A patent/AUPP584298A0/en not_active Abandoned
-
1999
- 1999-09-13 DE DE69937059T patent/DE69937059T2/de not_active Expired - Lifetime
- 1999-09-13 WO PCT/AU1999/000763 patent/WO2000015240A1/en not_active Ceased
- 1999-09-13 CN CN99812270A patent/CN1323214A/zh active Pending
- 1999-09-13 KR KR1020017003211A patent/KR100720905B1/ko not_active Expired - Lifetime
- 1999-09-13 EP EP99945773A patent/EP1113806B1/en not_active Expired - Lifetime
- 1999-09-13 NZ NZ510289A patent/NZ510289A/xx not_active IP Right Cessation
- 1999-09-13 CA CA002343113A patent/CA2343113C/en not_active Expired - Lifetime
- 1999-09-13 CN CNA2008100874448A patent/CN101352451A/zh active Pending
- 1999-09-13 AT AT99945773T patent/ATE372123T1/de not_active IP Right Cessation
- 1999-09-13 BR BR9913712-7A patent/BR9913712A/pt not_active Application Discontinuation
- 1999-09-13 JP JP2000569824A patent/JP4979848B2/ja not_active Expired - Lifetime
- 1999-09-13 US US09/786,913 patent/US6464971B1/en not_active Expired - Lifetime
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