JP2002522043A5 - - Google Patents
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- Publication number
- JP2002522043A5 JP2002522043A5 JP2000563821A JP2000563821A JP2002522043A5 JP 2002522043 A5 JP2002522043 A5 JP 2002522043A5 JP 2000563821 A JP2000563821 A JP 2000563821A JP 2000563821 A JP2000563821 A JP 2000563821A JP 2002522043 A5 JP2002522043 A5 JP 2002522043A5
- Authority
- JP
- Japan
- Prior art keywords
- organism
- group
- glycerol
- enzyme
- diol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000004190 Enzymes Human genes 0.000 description 9
- 108090000790 Enzymes Proteins 0.000 description 9
- 238000000034 method Methods 0.000 description 9
- REKYPYSUBKSCAT-UHFFFAOYSA-N 3-hydroxypentanoic acid Chemical compound CCC(O)CC(O)=O REKYPYSUBKSCAT-UHFFFAOYSA-N 0.000 description 8
- 239000000178 monomer Substances 0.000 description 7
- 108010065027 Propanediol Dehydratase Proteins 0.000 description 5
- ALRHLSYJTWAHJZ-UHFFFAOYSA-M 3-hydroxypropionate Chemical compound OCCC([O-])=O ALRHLSYJTWAHJZ-UHFFFAOYSA-M 0.000 description 4
- 150000002009 diols Chemical class 0.000 description 4
- 239000005014 poly(hydroxyalkanoate) Substances 0.000 description 4
- 229920000903 polyhydroxyalkanoate Polymers 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 108010011958 1,3-propanediol dehydrogenase Proteins 0.000 description 2
- 102100026105 3-ketoacyl-CoA thiolase, mitochondrial Human genes 0.000 description 2
- 108010003902 Acetyl-CoA C-acyltransferase Proteins 0.000 description 2
- 102000005369 Aldehyde Dehydrogenase Human genes 0.000 description 2
- 108020002663 Aldehyde Dehydrogenase Proteins 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- 108010025885 Glycerol dehydratase Proteins 0.000 description 2
- 108010041921 Glycerolphosphate Dehydrogenase Proteins 0.000 description 2
- 102000000587 Glycerolphosphate Dehydrogenase Human genes 0.000 description 2
- 102000003960 Ligases Human genes 0.000 description 2
- 108090000364 Ligases Proteins 0.000 description 2
- 108091000039 acetoacetyl-CoA reductase Proteins 0.000 description 2
- 125000002252 acyl group Chemical group 0.000 description 2
- 108010069175 acyl-CoA transferase Proteins 0.000 description 2
- 210000000349 chromosome Anatomy 0.000 description 2
- 108010032776 glycerol-1-phosphatase Proteins 0.000 description 2
- 239000013612 plasmid Substances 0.000 description 2
- 108010010718 poly(3-hydroxyalkanoic acid) synthase Proteins 0.000 description 2
- DNIAPMSPPWPWGF-VKHMYHEASA-N (+)-propylene glycol Chemical compound C[C@H](O)CO DNIAPMSPPWPWGF-VKHMYHEASA-N 0.000 description 1
- DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical compound C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 description 1
- YPFDHNVEDLHUCE-UHFFFAOYSA-N 1,3-propanediol Substances OCCCO YPFDHNVEDLHUCE-UHFFFAOYSA-N 0.000 description 1
- 108090001042 Hydro-Lyases Proteins 0.000 description 1
- 102000004867 Hydro-Lyases Human genes 0.000 description 1
- 239000005515 coenzyme Substances 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- DNIAPMSPPWPWGF-UHFFFAOYSA-N monopropylene glycol Natural products CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 1
- 229920000166 polytrimethylene carbonate Polymers 0.000 description 1
- 235000013772 propylene glycol Nutrition 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9532998P | 1998-08-04 | 1998-08-04 | |
| US60/095,329 | 1998-08-04 | ||
| PCT/US1999/017701 WO2000008198A1 (en) | 1998-08-04 | 1999-08-04 | Polyhydroxyalkanoate production from polyols |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002522043A JP2002522043A (ja) | 2002-07-23 |
| JP2002522043A5 true JP2002522043A5 (enExample) | 2006-09-14 |
| JP5042407B2 JP5042407B2 (ja) | 2012-10-03 |
Family
ID=22251426
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000563821A Expired - Fee Related JP5042407B2 (ja) | 1998-08-04 | 1999-08-04 | ポリオールからのポリヒドロキシアルカノエートの産生 |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US6329183B1 (enExample) |
| EP (2) | EP1975236B1 (enExample) |
| JP (1) | JP5042407B2 (enExample) |
| AT (1) | ATE385521T1 (enExample) |
| AU (1) | AU752513B2 (enExample) |
| CA (1) | CA2339351C (enExample) |
| DE (1) | DE69938105T2 (enExample) |
| ES (1) | ES2302386T3 (enExample) |
| MX (1) | MXPA01001111A (enExample) |
| WO (1) | WO2000008198A1 (enExample) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69938105T2 (de) | 1998-08-04 | 2009-01-29 | Metabolix, Inc., Cambridge | Herstellung von polyhydroxyalkanoaten aus polyolen |
| EP1700908B1 (en) * | 1998-08-18 | 2016-01-06 | Metabolix, Inc. | Transgenic microbial polyhydroxyalkanoate producers |
| DE69930276T2 (de) * | 1998-08-18 | 2006-10-05 | Metabolix, Inc., Cambridge | Transgene polyhydroxyalkanoat produzierende mikroben |
| WO2001016346A1 (en) * | 1999-08-30 | 2001-03-08 | Wisconsin Alumni Research Foundation | Production of 3-hydroxypropionic acid in recombinant organisms |
| US6852517B1 (en) * | 1999-08-30 | 2005-02-08 | Wisconsin Alumni Research Foundation | Production of 3-hydroxypropionic acid in recombinant organisms |
| US20020164729A1 (en) * | 2000-07-21 | 2002-11-07 | Skraly Frank A. | Production of polyhydroxyalkanoates from polyols |
| CA2428713C (en) * | 2000-11-17 | 2012-04-17 | Metabolix, Inc. | Production of medium chain length polyhydroxyalkanoates from fatty acid biosynthetic pathways |
| JP4490628B2 (ja) | 2000-11-20 | 2010-06-30 | カーギル インコーポレイテッド | ３−ヒドロキシプロピオン酸および他の有機化合物 |
| AU2002255657A1 (en) * | 2001-03-02 | 2002-09-19 | Ross Carlson | Production of polyhydroxyalkanoates |
| JP2003015168A (ja) * | 2001-04-27 | 2003-01-15 | Canon Inc | 電気泳動粒子、電気泳動粒子の製造方法、および電気泳動表示素子 |
| US7230144B2 (en) | 2001-12-18 | 2007-06-12 | Metabolix Inc. | Methods of making intermediates from polyhydroxyalkanoates |
| WO2004038030A2 (en) * | 2002-05-10 | 2004-05-06 | Metabolix, Inc. | Bioabsorbable polymer containing 2-hdroxyacid monomers |
| EP2365088B1 (en) | 2002-09-12 | 2015-05-27 | Metabolix, Inc. | Polyhydroxyalkanoate production by coenzyme a-dependent aldehyde dehydrogenase pathways |
| US7056439B2 (en) * | 2003-05-06 | 2006-06-06 | Tate & Lyle Ingredidents Americas, Inc. | Process for producing 1, 3-propanediol |
| EP1731604A4 (en) * | 2004-03-26 | 2007-04-04 | Nippon Catalytic Chem Ind | PROCESS FOR THE PREPARATION OF 1,3-PROPANEL AND / OR 3-HYDROXYPROPIONIC ACID |
| JP5279060B2 (ja) * | 2004-08-31 | 2013-09-04 | 独立行政法人理化学研究所 | 熱安定性バイオポリエステル |
| US7118897B2 (en) * | 2004-09-15 | 2006-10-10 | The Procter & Gamble Company | Process for the extraction of polyhydroxyalkanoates from biomass |
| WO2006065967A2 (en) * | 2004-12-15 | 2006-06-22 | General Atomics | Allosteric enzyme coupled immunoassay (aecia) |
| EP1863916B1 (en) | 2005-03-16 | 2011-08-24 | Metabolix, Inc. | Chemically inducible expression of biosynthetic pathways |
| KR100979694B1 (ko) * | 2005-05-24 | 2010-09-02 | 한국과학기술원 | 폴리락테이트 또는 그 공중합체 생성능을 가지는 세포 또는식물 및 이를 이용한 폴리락테이트 또는 그 공중합체의제조방법 |
| US8207398B2 (en) * | 2005-07-18 | 2012-06-26 | University Of Kentucky Research Foundation | Plants having an enhanced resistance to necrotrophic pathogens and method of making same |
| CN101300354A (zh) * | 2005-09-08 | 2008-11-05 | 梅雷迪安公司 | 具有改良的聚羟基链烷酸产生能力的去调节的细菌 |
| EP2001992B1 (en) | 2006-03-13 | 2016-07-20 | Cargill Inc. | Yeast cells having disrupted pathway from dihydroxyacetone phosphate to glycerol |
| US20080163390A1 (en) * | 2007-01-03 | 2008-07-03 | University Of Kentucky Research Foundation | Methods and compositions for providing sa-independent pathogen resistance in plants |
| AU2008206403A1 (en) * | 2007-01-12 | 2008-07-24 | The Regents Of The University Of Colorado, A Body Corporate | Compositions and methods for enhancing tolerance for the production of organic chemicals produced by microorganisms |
| US8673601B2 (en) | 2007-01-22 | 2014-03-18 | Genomatica, Inc. | Methods and organisms for growth-coupled production of 3-hydroxypropionic acid |
| CA2678946C (en) | 2007-03-16 | 2019-02-12 | Genomatica, Inc. | Compositions and methods for the biosynthesis of 1,4-butanediol and its precursors |
| US7947483B2 (en) | 2007-08-10 | 2011-05-24 | Genomatica, Inc. | Methods and organisms for the growth-coupled production of 1,4-butanediol |
| US8048624B1 (en) | 2007-12-04 | 2011-11-01 | Opx Biotechnologies, Inc. | Compositions and methods for 3-hydroxypropionate bio-production from biomass |
| CN101445813B (zh) * | 2007-12-21 | 2013-03-27 | 清华大学 | 一种生产3-羟基丙酸的方法 |
| US8048654B2 (en) | 2010-06-09 | 2011-11-01 | Joule Unlimited Technologies, Inc. | Methods and compositions for the recombinant biosynthesis of fatty acids and esters |
| CN102015995B (zh) | 2008-03-03 | 2014-10-22 | 焦耳无限科技公司 | 产生碳基目的产物的二氧化碳固定工程微生物 |
| KR101069016B1 (ko) | 2008-06-09 | 2011-09-29 | 주식회사 씨티씨바이오 | 글리세롤디하이드라타제 및 3-하이드록시프로피온알데히드디하이드로게나제를 코딩하는 유전자로 형질전환된 재조합미생물 및 상기 재조합 미생물을 이용한3-하이드록시프로피온산의 제조방법 |
| CA2735883C (en) | 2008-09-10 | 2020-05-05 | Genomatica, Inc. | Microorganisms for the production of 1,4-butanediol |
| EP2998402A1 (en) | 2008-10-17 | 2016-03-23 | Joule Unlimited Technologies, Inc. | Ethanol production by microorganisms |
| KR101293904B1 (ko) * | 2009-03-03 | 2013-08-16 | 주식회사 엘지화학 | 자일로스로부터 폴리락틱산 또는 폴리락틱산 공중합체를 제조할 수 있는 재조합 미생물 및 이러한 미생물을 이용하여 자일로스로부터 폴리락틱산 또는 락틱산 공중합체를 제조하는 방법 |
| SI3392340T1 (sl) | 2009-06-04 | 2022-05-31 | Genomatica, Inc. | Mikroorganizmi za proizvodnjo 1,4-BUTANDIOLA in pripadajoči postopki |
| LT2438036T (lt) | 2009-06-04 | 2017-06-26 | Genomatica, Inc. | Fermentacijos sultinio komponentų išskyrimo būdas |
| WO2011011464A2 (en) * | 2009-07-20 | 2011-01-27 | Joule Unlimited, Inc. | Constructs and methods for efficient transformation of micro-organisms for production of carbon-based products of interest |
| WO2011038364A1 (en) | 2009-09-27 | 2011-03-31 | Opx Biotechnologies, Inc. | Method for producing 3-hydroxypropionic acid and other products |
| US8809027B1 (en) | 2009-09-27 | 2014-08-19 | Opx Biotechnologies, Inc. | Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase |
| AU2010306785B2 (en) | 2009-10-13 | 2016-01-14 | Genomatica, Inc. | Microorganisms for the production of 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-CoA, putrescine and related compounds, and methods related thereto |
| EP2495328B1 (en) * | 2009-10-29 | 2016-03-30 | Korea Research Institute of Bioscience and Biotechnology | Novel method for producing 3-hydroxypropionic acid from glycerol |
| US8530210B2 (en) | 2009-11-25 | 2013-09-10 | Genomatica, Inc. | Microorganisms and methods for the coproduction 1,4-butanediol and gamma-butyrolactone |
| RU2012132908A (ru) | 2010-02-11 | 2014-03-20 | Метаболикс, Инк. | Способ получения производных химических соединений |
| US8637286B2 (en) | 2010-02-23 | 2014-01-28 | Genomatica, Inc. | Methods for increasing product yields |
| US8048661B2 (en) | 2010-02-23 | 2011-11-01 | Genomatica, Inc. | Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes |
| KR101312835B1 (ko) * | 2010-08-27 | 2013-09-27 | 주식회사 씨티씨바이오 | 알데히드 디하이드로지네이즈를 코딩하는 ｐｕｕＣ 유전자가 형질도입된 재조합 미생물 및 이를 이용한 3-하이드록시프로피온산 단독 혹은 １，３―프로판디올 및 ３―하이드록시프로피온산의 동시 제조방법 |
| MX2013005654A (es) | 2010-11-22 | 2013-07-17 | Novozymes Inc | Composiciones y metodos para la produccion de acido 3-hidroxipropionico. |
| WO2012075051A1 (en) | 2010-11-29 | 2012-06-07 | Micromidas, Inc. | Pha-producing bacteria |
| JP2012162471A (ja) * | 2011-02-04 | 2012-08-30 | Nippon Shokubai Co Ltd | アクリル酸およびその重合体の製造方法 |
| JP5878368B2 (ja) * | 2011-12-29 | 2016-03-08 | 株式会社日本触媒 | アクリル酸およびその重合体の製造方法 |
| TWI464261B (zh) * | 2012-03-12 | 2014-12-11 | Univ Yuan Ze | 以基因重組微生物進行碳源轉化生產生物降解高分子與生質燃料的方法 |
| US9169501B2 (en) | 2012-05-11 | 2015-10-27 | Yuan Ze University | Method for producing biodegradable polymer and biomass fuel converted from carbon source by recombinant microorganisms |
| US9359283B2 (en) | 2012-05-31 | 2016-06-07 | Micromidas, Inc. | Polyhydroxyalkanoate derivatives, preparation and uses thereof |
| EP3831951A3 (en) | 2012-06-04 | 2021-09-15 | Genomatica, Inc. | Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds |
| BR112014030203B1 (pt) | 2012-06-08 | 2021-10-13 | Cj Cheiljedang Corporation | Processo para produção de produtos de ácido acrílico de base biológica |
| BR112015002940A2 (pt) | 2012-08-10 | 2018-04-24 | Opx Biotechnologies Inc | microorganismos e métodos para a produção de ácidos graxos e produtos derivados de ácidos graxos. |
| WO2014127053A2 (en) | 2013-02-13 | 2014-08-21 | Metabolix, Inc. | Process for ultra pure chemical production from biobased raw starting materials |
| US9447438B2 (en) | 2013-03-15 | 2016-09-20 | Cargill, Incorporated | Acetyl-coA carboxylases |
| EP2976141A4 (en) | 2013-03-15 | 2016-10-05 | Cargill Inc | FLASHING FOR PRODUCTION CLEANING AND RECOVERY |
| WO2015010103A2 (en) | 2013-07-19 | 2015-01-22 | Opx Biotechnologies, Inc. | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
| US11408013B2 (en) | 2013-07-19 | 2022-08-09 | Cargill, Incorporated | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
| US9599606B2 (en) * | 2014-06-10 | 2017-03-21 | The Board Of Regents Of The University Of Texas System | ADP-ribose detection reagents |
| EP2993228B1 (en) | 2014-09-02 | 2019-10-09 | Cargill, Incorporated | Production of fatty acid esters |
| CN110494566A (zh) | 2017-02-02 | 2019-11-22 | 嘉吉公司 | 产生c6-c10脂肪酸衍生物的经遗传修饰的细胞 |
| CN109913510B (zh) * | 2019-03-29 | 2021-04-13 | 长春理工大学 | 一种聚羟基脂肪酸酯的体外合成方法 |
| KR102747615B1 (ko) * | 2019-09-27 | 2024-12-26 | 주식회사 엘지화학 | 폴리(3-하이드록시프로피오네이트)의 대량 생산공정 |
| KR102782737B1 (ko) | 2022-11-29 | 2025-03-19 | 씨제이제일제당 주식회사 | 신규한 프로피온알데하이드 디하이드로게나제 활성을 갖는 변이체 폴리펩티드 및 이의 용도 |
Family Cites Families (31)
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| US4159514A (en) * | 1977-11-16 | 1979-06-26 | Bell Telephone Laboratories, Incorporated | Signal loss detector for three phase circuit |
| IT1193453B (it) * | 1979-09-03 | 1988-06-22 | Puntimatic Snc D Musiani Franc | Dispositivo rivelatore di sovracorrente e di mancanza di fase |
| US4477654A (en) | 1981-07-07 | 1984-10-16 | Imperial Chemical Industries Plc | 3-Hydroxybutyrate polymers |
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| US5250430A (en) | 1987-06-29 | 1993-10-05 | Massachusetts Institute Of Technology | Polyhydroxyalkanoate polymerase |
| US5245023A (en) | 1987-06-29 | 1993-09-14 | Massachusetts Institute Of Technology | Method for producing novel polyester biopolymers |
| FR2627508B1 (fr) * | 1988-02-22 | 1990-10-05 | Eurolysine | Procede pour l'integration d'un gene choisi sur le chromosome d'une bacterie et bacterie obtenue par ledit procede |
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| DE69938105T2 (de) * | 1998-08-04 | 2009-01-29 | Metabolix, Inc., Cambridge | Herstellung von polyhydroxyalkanoaten aus polyolen |
| DK1163019T3 (da) | 1999-03-25 | 2008-03-03 | Metabolix Inc | Medicinske indretninger og anvendelser af polyhydroxyalkanoatpolymere |
| US6769081B1 (en) * | 2000-08-30 | 2004-07-27 | Sun Microsystems, Inc. | Reconfigurable built-in self-test engine for testing a reconfigurable memory |
| CA2428713C (en) | 2000-11-17 | 2012-04-17 | Metabolix, Inc. | Production of medium chain length polyhydroxyalkanoates from fatty acid biosynthetic pathways |
| WO2004038030A2 (en) | 2002-05-10 | 2004-05-06 | Metabolix, Inc. | Bioabsorbable polymer containing 2-hdroxyacid monomers |
-
1999
- 1999-08-04 DE DE69938105T patent/DE69938105T2/de not_active Expired - Lifetime
- 1999-08-04 ES ES99939003T patent/ES2302386T3/es not_active Expired - Lifetime
- 1999-08-04 WO PCT/US1999/017701 patent/WO2000008198A1/en not_active Ceased
- 1999-08-04 MX MXPA01001111A patent/MXPA01001111A/es not_active IP Right Cessation
- 1999-08-04 JP JP2000563821A patent/JP5042407B2/ja not_active Expired - Fee Related
- 1999-08-04 US US09/366,920 patent/US6329183B1/en not_active Expired - Lifetime
- 1999-08-04 EP EP20070025203 patent/EP1975236B1/en not_active Expired - Lifetime
- 1999-08-04 AT AT99939003T patent/ATE385521T1/de not_active IP Right Cessation
- 1999-08-04 CA CA002339351A patent/CA2339351C/en not_active Expired - Lifetime
- 1999-08-04 AU AU53372/99A patent/AU752513B2/en not_active Expired
- 1999-08-04 EP EP99939003A patent/EP1105514B1/en not_active Expired - Lifetime
-
2001
- 2001-08-30 US US09/944,243 patent/US6576450B2/en not_active Expired - Fee Related
-
2003
- 2003-05-21 US US10/444,031 patent/US20040023347A1/en not_active Abandoned
-
2005
- 2005-03-04 US US11/072,735 patent/US8114643B2/en not_active Expired - Fee Related
-
2012
- 2012-01-27 US US13/359,978 patent/US8609378B2/en not_active Expired - Fee Related
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