JP2002521484A5 - - Google Patents
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- Publication number
- JP2002521484A5 JP2002521484A5 JP2000562374A JP2000562374A JP2002521484A5 JP 2002521484 A5 JP2002521484 A5 JP 2002521484A5 JP 2000562374 A JP2000562374 A JP 2000562374A JP 2000562374 A JP2000562374 A JP 2000562374A JP 2002521484 A5 JP2002521484 A5 JP 2002521484A5
- Authority
- JP
- Japan
- Prior art keywords
- mmol
- solution
- cdcl
- added
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98114067.6 | 1998-07-28 | ||
| EP98114067A EP0976752A1 (en) | 1998-07-28 | 1998-07-28 | C-2 S/O- and S/N-Formaldehyde acetal derivatives of carbapenem antibiotics |
| PCT/EP1999/005295 WO2000006574A1 (en) | 1998-07-28 | 1999-07-23 | NOVEL C-2 S/O- AND S/N FORMALDEHYDE ACETAL DERIVATIVES OF CARBAPENEM-3-CARBOXYLIC ACIDS AND THEIR USE AS ANTIBIOTICS AND β-LACTAMASE INHIBITORS |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002521484A JP2002521484A (ja) | 2002-07-16 |
| JP2002521484A5 true JP2002521484A5 (enExample) | 2006-09-14 |
| JP4598273B2 JP4598273B2 (ja) | 2010-12-15 |
Family
ID=8232355
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000562374A Expired - Fee Related JP4598273B2 (ja) | 1998-07-28 | 1999-07-23 | カルバペネム−３−カルボン酸の新規Ｃ−２Ｓ／Ｏ−及びＳ／Ｎホルムアルデヒドアセタール誘導体並びにそれらの抗生物質及びβ−ラクタマーゼインヒビターとしての使用 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6482818B2 (enExample) |
| EP (2) | EP0976752A1 (enExample) |
| JP (1) | JP4598273B2 (enExample) |
| KR (1) | KR20010086351A (enExample) |
| CN (1) | CN1154649C (enExample) |
| AT (1) | ATE243696T1 (enExample) |
| AU (1) | AU760249B2 (enExample) |
| CA (1) | CA2338776C (enExample) |
| DE (1) | DE69909098T2 (enExample) |
| ES (1) | ES2203164T3 (enExample) |
| HU (1) | HUP0102729A3 (enExample) |
| IL (1) | IL141114A (enExample) |
| MX (1) | MXPA01000905A (enExample) |
| NZ (1) | NZ509578A (enExample) |
| PT (1) | PT1100800E (enExample) |
| WO (1) | WO2000006574A1 (enExample) |
| ZA (1) | ZA200100737B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2007002284A (es) * | 2004-08-23 | 2009-02-12 | Sicor Inc | Síntesis de idarubicina aglicona. |
| ES2428167T3 (es) | 2007-05-21 | 2013-11-06 | Hans Rudolf Pfaendler | Composición farmacéutica bactericida activa anti-MRSA conteniendo carbapenemos |
| CN101412718B (zh) * | 2007-10-19 | 2011-04-27 | 山东轩竹医药科技有限公司 | 含有硫基杂环胺甲酰基的碳青霉烯衍生物 |
| CN103059028B (zh) * | 2013-01-30 | 2014-05-07 | 山东罗欣药业股份有限公司 | 一种替比培南匹伏酯的制备方法 |
| CN114957258A (zh) * | 2021-02-25 | 2022-08-30 | 华东理工大学 | 基于碳青霉烯结构的广谱丝氨酸β-内酰胺酶抑制剂的合成及其在耐药细菌抑制中的应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3274861D1 (en) * | 1981-11-10 | 1987-02-05 | Shionogi & Co | Pluracidomycin b,c, and d and analogs thereof, their production and a microorganism for use therein |
| JPS58116485A (ja) * | 1981-12-29 | 1983-07-11 | Shionogi & Co Ltd | 新規抗生物質カルバペネム誘導体およびその製造法 |
| JPS58124785A (ja) * | 1982-01-20 | 1983-07-25 | Shionogi & Co Ltd | プルラシドマイシンｂおよびｃのデオキシ体ならびにその製造法 |
| JPS6054387A (ja) * | 1983-08-03 | 1985-03-28 | メルク エンド カムパニ− インコ−ポレ−テツド | チエナマイシンの誘導体製造法 |
| CA1285940C (en) * | 1984-07-02 | 1991-07-09 | Merck & Co., Inc. | Carbapenems having a 2-quaternary heteroarylalkylthio substituent |
| IE851586L (en) * | 1984-07-02 | 1986-01-02 | Interchem Internat S A | I methylcarbapenems having a 2-quaternary¹heteroarylalkylthio substituent |
| JPS63255283A (ja) * | 1987-04-11 | 1988-10-21 | Nippon Redarii Kk | （１ｒ，５ｓ，６ｓ）−２−〔（３−置換イミダゾリニウム−１−イル）アルキル〕チオ−６−〔（ｒ）−１−ヒドロキシエチル〕−１−メチル−カルバペネム−３−カルボキシレ−ト |
| US5116833A (en) * | 1990-10-19 | 1992-05-26 | Bristol-Myers Squibb Company | Antibiotic c-3 dithioacetal-substituted carbapenem compounds, compositions, and methods of use thereof |
-
1998
- 1998-07-28 EP EP98114067A patent/EP0976752A1/en not_active Withdrawn
-
1999
- 1999-07-23 CN CNB998091634A patent/CN1154649C/zh not_active Expired - Fee Related
- 1999-07-23 AU AU51639/99A patent/AU760249B2/en not_active Ceased
- 1999-07-23 JP JP2000562374A patent/JP4598273B2/ja not_active Expired - Fee Related
- 1999-07-23 PT PT99936602T patent/PT1100800E/pt unknown
- 1999-07-23 CA CA002338776A patent/CA2338776C/en not_active Expired - Fee Related
- 1999-07-23 DE DE69909098T patent/DE69909098T2/de not_active Expired - Lifetime
- 1999-07-23 AT AT99936602T patent/ATE243696T1/de not_active IP Right Cessation
- 1999-07-23 KR KR1020017001122A patent/KR20010086351A/ko not_active Ceased
- 1999-07-23 ES ES99936602T patent/ES2203164T3/es not_active Expired - Lifetime
- 1999-07-23 MX MXPA01000905A patent/MXPA01000905A/es not_active IP Right Cessation
- 1999-07-23 IL IL14111499A patent/IL141114A/en not_active IP Right Cessation
- 1999-07-23 NZ NZ509578A patent/NZ509578A/xx not_active IP Right Cessation
- 1999-07-23 HU HU0102729A patent/HUP0102729A3/hu unknown
- 1999-07-23 WO PCT/EP1999/005295 patent/WO2000006574A1/en not_active Ceased
- 1999-07-23 EP EP99936602A patent/EP1100800B1/en not_active Expired - Lifetime
-
2001
- 2001-01-25 ZA ZA200100737A patent/ZA200100737B/en unknown
- 2001-01-25 US US09/770,536 patent/US6482818B2/en not_active Expired - Fee Related
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