JP2002518011A - 殺菌性／透過性増加タンパク質（ｂｐｉ）欠失アナログ - Google Patents
殺菌性／透過性増加タンパク質（ｂｐｉ）欠失アナログInfo
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- JP2002518011A JP2002518011A JP2000554853A JP2000554853A JP2002518011A JP 2002518011 A JP2002518011 A JP 2002518011A JP 2000554853 A JP2000554853 A JP 2000554853A JP 2000554853 A JP2000554853 A JP 2000554853A JP 2002518011 A JP2002518011 A JP 2002518011A
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4742—Bactericidal/Permeability-increasing protein [BPI]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/099,725 | 1998-06-19 | ||
| US09/099,725 US6013631A (en) | 1998-06-19 | 1998-06-19 | Bactericidal/permeability-increasing protein (BPI) deletion analogs |
| PCT/US1999/013860 WO1999066044A1 (en) | 1998-06-19 | 1999-06-18 | Bactericidal/permeability-increasing protein (bpi) deletion analogs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002518011A true JP2002518011A (ja) | 2002-06-25 |
| JP2002518011A5 JP2002518011A5 (https=) | 2006-06-29 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000554853A Pending JP2002518011A (ja) | 1998-06-19 | 1999-06-18 | 殺菌性／透過性増加タンパク質（ｂｐｉ）欠失アナログ |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US6013631A (https=) |
| EP (1) | EP1086230A1 (https=) |
| JP (1) | JP2002518011A (https=) |
| CN (1) | CN1273598C (https=) |
| AU (1) | AU755624B2 (https=) |
| CA (1) | CA2331880A1 (https=) |
| MX (1) | MXPA00011398A (https=) |
| NZ (1) | NZ508816A (https=) |
| WO (1) | WO1999066044A1 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JPWO2004075913A1 (ja) * | 2003-02-28 | 2006-06-01 | 中外製薬株式会社 | タンパク質含有安定化製剤 |
| CN115777018A (zh) * | 2020-07-10 | 2023-03-10 | 株式会社绿十字 | 用于产生水痘-带状疱疹病毒表面蛋白抗原的方法 |
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| US5198541A (en) * | 1987-08-11 | 1993-03-30 | New York University | Dna encoding bactericidal/permeability-increasing proteins |
| US6013631A (en) * | 1998-06-19 | 2000-01-11 | Xoma Corporation | Bactericidal/permeability-increasing protein (BPI) deletion analogs |
| JP2003500363A (ja) * | 1999-05-24 | 2003-01-07 | ゾーマ（ユーエス） エルエルシー | 滲出を伴う中耳炎を有するヒトにおけるｂｐｉタンパク質産物の治療的使用 |
| JP2004517865A (ja) * | 2000-12-01 | 2004-06-17 | ゾーマ テクノロジー リミテッド | Ｂｐｉタンパク質産物またはｂｐｉインヒビターを使用する、周皮細胞増殖の調節 |
| EP1492874B1 (en) | 2002-03-29 | 2011-01-19 | XOMA Technology Ltd. | Multigenic vector plasmids and methods for increasing expression of recombinant polypeptides |
| JP2008541746A (ja) * | 2005-06-03 | 2008-11-27 | ビオヴィトルム・アクチボラゲット（プブリクト） | 新規プロセス |
| EP1741440A1 (en) | 2005-07-08 | 2007-01-10 | Mellitus S.L. | Use of BPI protein for the treatment of disorders of the metabolism and cardiovascular disorders |
| US8338376B2 (en) * | 2006-10-20 | 2012-12-25 | Biogen Idec Ma Inc. | Compositions comprising variant LT-B-R-IG fusion proteins |
| JP5431171B2 (ja) * | 2007-03-15 | 2014-03-05 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 自己免疫障害の処置 |
| CN108042807B (zh) | 2011-04-05 | 2020-10-16 | 达纳-法伯癌症研究所有限公司 | 作为辐射缓和剂和辐射防护剂的bpi和其同源物的用途 |
| GB201319621D0 (en) | 2013-11-06 | 2013-12-18 | Norwegian University Of Science And Technology | Antimicrobial agents and their use in therapy |
| GB201319620D0 (en) | 2013-11-06 | 2013-12-18 | Norwegian University Of Science And Technology | Immunosuppressive agents and their use in therapy |
| CN115947868A (zh) * | 2022-09-28 | 2023-04-11 | 安君(北京)基因科技有限责任公司 | Cxcl-bpi融合蛋白及其用途 |
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| US5576292A (en) * | 1987-08-11 | 1996-11-19 | New York University | Biologically active bactericidal/permeability-increasing protein fragments |
| US5198541A (en) * | 1987-08-11 | 1993-03-30 | New York University | Dna encoding bactericidal/permeability-increasing proteins |
| US5089274A (en) * | 1989-02-14 | 1992-02-18 | Incyte Pharmaceuticals, Inc. | Use of bactericidal/permeability increasing protein or biologically active analogs thereof to treat endotoxin-related disorders |
| US5308834A (en) * | 1989-02-14 | 1994-05-03 | Incyte Pharmaceuticals, Inc. | Treatment of endotoxin-associated shock and prevention thereof using a BPI protein |
| US5334584A (en) * | 1989-02-14 | 1994-08-02 | Incyte Pharamaceuticals, Inc. | Recombinant, non-glycosylated bpi protein and uses thereof |
| US5234912A (en) * | 1989-02-14 | 1993-08-10 | Incyte Pharmaceuticals, Inc. | Pharmaceutical compositions comprising recombinant BPI proteins and a lipid carrier and uses thereof |
| US5770694A (en) * | 1990-08-13 | 1998-06-23 | Incyte Pharmaceuticals, Inc. | Genetically engineered BPI variant proteins |
| US5171739A (en) * | 1989-02-14 | 1992-12-15 | Incyte Pharmaceuticals, Inc. | Treatment of endotoxin-associated shock and preventation thereof using a BPI protein |
| EP0563222B1 (en) * | 1990-12-03 | 1998-02-25 | New York University | Biologically active bactericidal/permeability-increasing protein fragments |
| EP0605653A4 (en) * | 1991-09-26 | 1995-03-15 | Incyte Pharma Inc | NEW LIPOSACCHARID BINDING PROTEIN (LBP). |
| US5643570A (en) * | 1992-05-19 | 1997-07-01 | Xoma Corporation | BPI-immunoglobulin fusion proteins |
| ES2132239T3 (es) * | 1992-05-19 | 1999-08-16 | Xoma Corp | Metodos mejorados para la preparacion de proteinas de union a endotoxinas. |
| US5420019A (en) * | 1993-02-02 | 1995-05-30 | Xoma Corporation | Stable bactericidal/permeability-increasing protein muteins |
| PT682524E (pt) * | 1993-02-02 | 2002-03-28 | Xoma Technology Ltd | Composicoes farmaceuticas que contem a proteina bactericida indutora da permeabilidade e um agente tensioactivo |
| ES2116583T3 (es) | 1993-02-18 | 1998-07-16 | Merck Sharp & Dohme | Compuestos azaciclicos, composiciones que los contienen y su uso como antagonistas de taquicininas. |
| US5652332A (en) * | 1993-03-12 | 1997-07-29 | Xoma | Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof |
| US5348942A (en) * | 1993-03-12 | 1994-09-20 | Xoma Corporation | Therapeutic uses of bactericidal/permeability increasing protein products |
| DE69412243T2 (de) * | 1993-03-12 | 1999-03-25 | Xoma Corp., Berkeley, Calif. | Biologisch aktive peptide aus funktionellen domaenen des bakteriziden/ die permeabilitaet erhoehenden proteins und ihre verwendung |
| EP0690720B1 (en) * | 1993-03-12 | 2001-06-27 | XOMA Technology Ltd. | Therapeutic uses of bactericidal/permeability increasing protein products |
| DE69410254T2 (de) * | 1993-03-12 | 1998-12-17 | Xoma Corp., Berkeley, Calif. | Behandlung von mycobakteriellen erkrankungen durch verabreichung von bakrerientötende, durchlässigkeitserhöhende proteinfragmente |
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| AU6522794A (en) * | 1993-03-22 | 1994-10-11 | Incyte Pharmaceuticals, Inc. | Use of bactericidal/permeability increasing protein and lipopolysaccharide binding protein levels and ratios thereof in diagnosis |
| JPH08511682A (ja) * | 1993-04-30 | 1996-12-10 | インサイト ファーマシューティカルズ，インク． | 組み換えｂｐｉ蛋白およびｌｂｐ蛋白、それをコードする核酸分子、その生産方法並びにそれらの使用 |
| US5731415A (en) * | 1993-06-17 | 1998-03-24 | Xoma Corporation | Lipopolysaccharide binding protein derivatives |
| EP0726944B1 (en) * | 1993-07-02 | 2002-12-18 | Incyte Pharmaceuticals, Inc. | Glycosylated and non-glycosylated bactericidal/permeability increasing proteins, and methods for producing same |
| AU7330994A (en) * | 1993-07-14 | 1995-02-13 | Xoma Corporation | Method for potentiating bpi protein product bactericidal activity by administration of lbp protein products |
| US5770561A (en) * | 1993-07-14 | 1998-06-23 | Xoma Corporation | Method for potentiating BPI protein product bactericidal activity by administration of LBP protein products |
| JPH09502987A (ja) * | 1993-09-22 | 1997-03-25 | ゾーマ コーポレイション | 殺菌性／浸透性が向上した（ｂｐｉ）タンパク質生成物および抗生物質の投与によるグラム陰性細菌感染の治療方法 |
| CN1133634A (zh) * | 1993-09-22 | 1996-10-16 | 爱克斯欧玛公司 | 定量体液中的bpi的方法 |
| US5466580A (en) * | 1993-09-22 | 1995-11-14 | Xoma Corporation | Method for quantifying BPI in body fluids |
| DE69433848T2 (de) * | 1993-10-05 | 2005-05-25 | Xoma Technology Ltd., Berkeley | Bpi-protein-produkte für definierte funktionen des reticuloendothelialen systems |
| EP0754050B1 (en) * | 1994-01-14 | 2002-06-26 | XOMA Technology Ltd. | Anti gram positive bacterial methods and materials |
| DE69526216T2 (de) * | 1994-01-14 | 2002-11-14 | Xoma Technology Ltd., Berkeley | Antifungaleverfahren und mitteln |
| US5484705A (en) * | 1994-01-24 | 1996-01-16 | Xoma Corporation | Method for quantifying lipopolysaccharide binding protein |
| US5643875A (en) * | 1994-01-24 | 1997-07-01 | Friedmann; Nadav | Human therapeutic uses of bactericidal/permeability increasing (BPI) protein products |
| US5447913A (en) * | 1994-03-11 | 1995-09-05 | Xoma Corporation | Therapeutic uses of bactericidal/permeability-increasing protein dimer products |
| US5786324A (en) * | 1994-03-24 | 1998-07-28 | Regents Of The University Of Minnesota | Synthetic peptides with bactericidal activity and endotoxin neutralizing activity for gram negative bacteria and methods for their use |
| US5578568A (en) * | 1994-04-22 | 1996-11-26 | Xoma Corporation | Method of treating conditions associated with intestinal ischemia/reperfusion |
| US5532216A (en) * | 1994-06-24 | 1996-07-02 | Incyte Pharmaceuticals, Inc. | Neutralization of non-lipopolysaccharide compounds by bactericidal/permeability-increasing protein |
| US5646114A (en) * | 1994-07-11 | 1997-07-08 | Xoma Corporation | Anti-protozoan methods |
| AU709738B2 (en) * | 1994-09-15 | 1999-09-02 | Xoma Corporation | Anti-fungal peptides |
| US5912228A (en) * | 1995-01-13 | 1999-06-15 | Xoma Corporation | Therapeutic compositions comprising bactericidal/permeability-increasing (BPI) protein products |
| US5494896A (en) * | 1995-03-31 | 1996-02-27 | Xoma Corporation | Method of treating conditions associated with burn injuries |
| WO1997004008A1 (en) * | 1995-07-20 | 1997-02-06 | Xoma Corporation | Anti-fungal peptides |
| US5686414A (en) * | 1995-11-14 | 1997-11-11 | Xoma Corporation | Methods of treating conditions associated with corneal transplantation |
| WO1997017990A1 (en) * | 1995-11-14 | 1997-05-22 | Xoma Corporation | Bactericidal permeability increasing protein (bpi) for treating conditions associated with corneal injury |
| US5741779A (en) * | 1996-05-10 | 1998-04-21 | Xoma Corporation | Antithrombotic materials and methods |
| CN1236320A (zh) * | 1996-05-10 | 1999-11-24 | 爱克斯欧玛公司 | 杀菌的/增强通透性的蛋白质产物用于人脑膜炎球菌血症的治疗用途 |
| ATE234111T1 (de) * | 1996-05-23 | 2003-03-15 | Xoma Technology Ltd | Therapeutische verwendungen von bpi-protein produkten bei menschen mit durch trauma verursachter blutung |
| US5888973A (en) * | 1996-08-09 | 1999-03-30 | Xoma Corporation | Anti-chlamydial uses of BPI protein products |
| WO1998019694A1 (en) * | 1996-11-01 | 1998-05-14 | Xoma Corporation | Therapeutic uses of bpi protein products in cystic fibrosis patients |
| US6013631A (en) * | 1998-06-19 | 2000-01-11 | Xoma Corporation | Bactericidal/permeability-increasing protein (BPI) deletion analogs |
-
1998
- 1998-06-19 US US09/099,725 patent/US6013631A/en not_active Expired - Lifetime
-
1999
- 1999-06-18 CA CA002331880A patent/CA2331880A1/en not_active Abandoned
- 1999-06-18 MX MXPA00011398A patent/MXPA00011398A/es unknown
- 1999-06-18 WO PCT/US1999/013860 patent/WO1999066044A1/en not_active Ceased
- 1999-06-18 NZ NZ508816A patent/NZ508816A/xx unknown
- 1999-06-18 CN CNB998097268A patent/CN1273598C/zh not_active Expired - Fee Related
- 1999-06-18 AU AU46976/99A patent/AU755624B2/en not_active Ceased
- 1999-06-18 US US09/336,402 patent/US6087126A/en not_active Expired - Fee Related
- 1999-06-18 JP JP2000554853A patent/JP2002518011A/ja active Pending
- 1999-06-18 EP EP99930432A patent/EP1086230A1/en not_active Withdrawn
-
2000
- 2000-05-25 US US09/579,403 patent/US6599880B1/en not_active Expired - Fee Related
-
2003
- 2003-07-29 US US10/629,516 patent/US20050130889A1/en not_active Abandoned
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2004075913A1 (ja) * | 2003-02-28 | 2006-06-01 | 中外製薬株式会社 | タンパク質含有安定化製剤 |
| CN115777018A (zh) * | 2020-07-10 | 2023-03-10 | 株式会社绿十字 | 用于产生水痘-带状疱疹病毒表面蛋白抗原的方法 |
| JP2023533160A (ja) * | 2020-07-10 | 2023-08-02 | グリーン・クロス・コーポレイション | 水痘帯状疱疹ウイルス表面タンパク質抗原を生産するための方法 |
| JP7487858B2 (ja) | 2020-07-10 | 2024-05-21 | グリーン・クロス・コーポレイション | 水痘帯状疱疹ウイルス表面タンパク質抗原を生産するための方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999066044A1 (en) | 1999-12-23 |
| CN1273598C (zh) | 2006-09-06 |
| US20050130889A1 (en) | 2005-06-16 |
| NZ508816A (en) | 2003-03-28 |
| MXPA00011398A (es) | 2003-04-22 |
| US6013631A (en) | 2000-01-11 |
| US6087126A (en) | 2000-07-11 |
| US6599880B1 (en) | 2003-07-29 |
| CN1312858A (zh) | 2001-09-12 |
| EP1086230A1 (en) | 2001-03-28 |
| AU4697699A (en) | 2000-01-05 |
| AU755624B2 (en) | 2002-12-19 |
| CA2331880A1 (en) | 1999-12-23 |
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