EP0605653A4 - A new form of liposaccharide binding protein (lbp). - Google Patents

A new form of liposaccharide binding protein (lbp).

Info

Publication number
EP0605653A4
EP0605653A4 EP92922186A EP92922186A EP0605653A4 EP 0605653 A4 EP0605653 A4 EP 0605653A4 EP 92922186 A EP92922186 A EP 92922186A EP 92922186 A EP92922186 A EP 92922186A EP 0605653 A4 EP0605653 A4 EP 0605653A4
Authority
EP
European Patent Office
Prior art keywords
lbp
binding protein
new form
liposaccharide
liposaccharide binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP92922186A
Other languages
German (de)
French (fr)
Other versions
EP0605653A1 (en
Inventor
Jeffrey J Seilhamer
Angelo M Delegeane
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Incyte Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharmaceuticals Inc filed Critical Incyte Pharmaceuticals Inc
Publication of EP0605653A1 publication Critical patent/EP0605653A1/en
Publication of EP0605653A4 publication Critical patent/EP0605653A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP92922186A 1991-09-26 1992-09-28 A new form of liposaccharide binding protein (lbp). Withdrawn EP0605653A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US76566091A 1991-09-26 1991-09-26
US765660 1991-09-26
PCT/US1992/008298 WO1993006228A1 (en) 1991-09-26 1992-09-28 A new form of liposaccharide binding protein (lbp)

Publications (2)

Publication Number Publication Date
EP0605653A1 EP0605653A1 (en) 1994-07-13
EP0605653A4 true EP0605653A4 (en) 1995-03-15

Family

ID=25074151

Family Applications (1)

Application Number Title Priority Date Filing Date
EP92922186A Withdrawn EP0605653A4 (en) 1991-09-26 1992-09-28 A new form of liposaccharide binding protein (lbp).

Country Status (4)

Country Link
EP (1) EP0605653A4 (en)
JP (1) JPH07502642A (en)
AU (1) AU2872792A (en)
WO (1) WO1993006228A1 (en)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6265187B1 (en) 1989-02-14 2001-07-24 Incyte Pharmaceuticals, Inc. Recombinant endotoxin-neutralizing proteins
DE69428521T2 (en) * 1993-02-02 2002-05-23 Xoma Technology Ltd MEDICINAL COMPOSITIONS CONTAINING A BACTERICIDAL PERMEABILITY-INCREASING PROTEIN AND A SURFACTANT
US5420019A (en) 1993-02-02 1995-05-30 Xoma Corporation Stable bactericidal/permeability-increasing protein muteins
US6214789B1 (en) 1993-03-12 2001-04-10 Xoma Corporation Treatment of mycobacterial diseases by administration of bactericidal/permeability-increasing protein products
US5652332A (en) * 1993-03-12 1997-07-29 Xoma Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof
AU6942994A (en) * 1993-04-30 1994-11-21 Incyte Pharmaceuticals, Inc. Recombinant bpi-based and lbp-based proteins, nucleic acid molecules encoding same, methods of producing same, and uses thereof
AU7175694A (en) 1993-06-17 1995-01-17 Xoma Corporation Lipopolysaccharide binding protein derivatives
US5770561A (en) * 1993-07-14 1998-06-23 Xoma Corporation Method for potentiating BPI protein product bactericidal activity by administration of LBP protein products
AU7330994A (en) * 1993-07-14 1995-02-13 Xoma Corporation Method for potentiating bpi protein product bactericidal activity by administration of lbp protein products
PT759774E (en) * 1993-09-22 2002-11-29 Xoma Technology Ltd METHOD FOR THE TREATMENT OF GRAM-NEGATIVE BACTERIAL INFECTIONS BY ADMINISTRATION OF A PERMEABILITY INDUCTIVE BACTERICIDE PROTEIN (BIP) PRODUCT AND ANTIBIOTIC
CN1133634A (en) * 1993-09-22 1996-10-16 爱克斯欧玛公司 Method for quantifying BPI in body fluids
US6759203B1 (en) 1993-09-22 2004-07-06 Xoma Corporation Method for quantifying BPI in body fluids
ES2179095T3 (en) * 1994-01-14 2003-01-16 Xoma Technology Ltd POSITIVE GRAM POSITIVE METHODS AND MATERIALS.
CN1112933C (en) * 1994-01-14 2003-07-02 爱克索马技术有限公司 Anti-fungal methods and materials
US5891618A (en) 1994-01-24 1999-04-06 Xoma Corporation Method for quantifying LBP in body fluids
US5484705A (en) * 1994-01-24 1996-01-16 Xoma Corporation Method for quantifying lipopolysaccharide binding protein
US5578568A (en) 1994-04-22 1996-11-26 Xoma Corporation Method of treating conditions associated with intestinal ischemia/reperfusion
US5932544A (en) * 1994-05-31 1999-08-03 Xoma Corporation Bactericidal/permeability-increasing protein (BPI) compositions
US5932536A (en) * 1994-06-14 1999-08-03 The Rockefeller University Compositions for neutralization of lipopolysaccharides
US5646114A (en) * 1994-07-11 1997-07-08 Xoma Corporation Anti-protozoan methods
US6271203B1 (en) 1994-07-07 2001-08-07 Xoma Corporation Anti-protozoan methods and materials
US5494896A (en) * 1995-03-31 1996-02-27 Xoma Corporation Method of treating conditions associated with burn injuries
EP0839156A1 (en) * 1995-07-20 1998-05-06 Xoma Corporation Anti-fungal peptides
ATE198050T1 (en) 1996-05-10 2000-12-15 Xoma Technology Ltd THERAPEUTIC USES OF BPI PROTEIN PRODUCTS FOR THE TREATMENT OF HUMAN MENINGOCOCCEMIA
JP2000511190A (en) * 1996-05-23 2000-08-29 ゾーマ コーポレイション Therapeutic use of BPI protein products in humans suffering from bleeding due to trauma
US5888973A (en) 1996-08-09 1999-03-30 Xoma Corporation Anti-chlamydial uses of BPI protein products
US6482796B2 (en) 1996-11-01 2002-11-19 Xoma Corporation Therapeutic uses of N-terminal BPI protein products in ANCA-positive patients
US6093573A (en) * 1997-06-20 2000-07-25 Xoma Three-dimensional structure of bactericidal/permeability-increasing protein (BPI)
US5990082A (en) * 1997-10-22 1999-11-23 Xoma Corporation Uses of lipopolysaccharide binding protein
US6013631A (en) 1998-06-19 2000-01-11 Xoma Corporation Bactericidal/permeability-increasing protein (BPI) deletion analogs
US7951781B2 (en) 2006-11-02 2011-05-31 University Of Iowa Research Foundation Methods and compositions related to PLUNC surfactant polypeptides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4943527A (en) * 1985-10-04 1990-07-24 California Biotechnology Inc. Mature apoai protein production under serum free culturing conditions
US5089274A (en) * 1989-02-14 1992-02-18 Incyte Pharmaceuticals, Inc. Use of bactericidal/permeability increasing protein or biologically active analogs thereof to treat endotoxin-related disorders

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
P. TOBIAS ET AL: "Isolation of a lipopolysaccharide-binding acute phase reactant from rabbit serum", J. EXP. MED., vol. 164, September 1986 (1986-09-01), pages 777 - 793 *
See also references of WO9306228A1 *

Also Published As

Publication number Publication date
JPH07502642A (en) 1995-03-23
WO1993006228A1 (en) 1993-04-01
EP0605653A1 (en) 1994-07-13
AU2872792A (en) 1993-04-27

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Legal Events

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