JP2002515816A - ｉｎ ｖｉｖｏ組織に核酸ベクターを最適に電気導入する装置 - Google Patents

ｉｎ ｖｉｖｏ組織に核酸ベクターを最適に電気導入する装置

Info

Publication number
JP2002515816A
JP2002515816A JP50807599A JP50807599A JP2002515816A JP 2002515816 A JP2002515816 A JP 2002515816A JP 50807599 A JP50807599 A JP 50807599A JP 50807599 A JP50807599 A JP 50807599A JP 2002515816 A JP2002515816 A JP 2002515816A
Authority
JP
Japan
Prior art keywords
electrode
pulse
electric field
tissue
electrodes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP50807599A
Other languages
English (en)
Japanese (ja)
Inventor
ビユロー，ミシエル
ミル，リユイス
シエルマン，ダニエル
シユバルツ，ベルトラン
Original Assignee
アバンテイス・フアルマ・エス・アー
アンステイテユ・ギユスタブ・ルシー
サントル・ナシオナル・ドウ・ラ・ルシエルシユ・シアンテイフイク
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9708233A external-priority patent/FR2765242B1/fr
Priority claimed from FR9708232A external-priority patent/FR2765241B1/fr
Application filed by アバンテイス・フアルマ・エス・アー, アンステイテユ・ギユスタブ・ルシー, サントル・ナシオナル・ドウ・ラ・ルシエルシユ・シアンテイフイク filed Critical アバンテイス・フアルマ・エス・アー
Publication of JP2002515816A publication Critical patent/JP2002515816A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP50807599A 1997-06-30 1998-06-30 ｉｎ ｖｉｖｏ組織に核酸ベクターを最適に電気導入する装置 Pending JP2002515816A (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
FR9708233A FR2765242B1 (fr) 1997-06-30 1997-06-30 Amelioration du transfert d'acide nucleique dans le muscle strie et combinaison permettant la mise en oeuvre du procede
FR9708232A FR2765241B1 (fr) 1997-06-30 1997-06-30 Amelioration du transfert d'acide nucleique dans les cellules d'organismes eucaryotes pluricellulaires et combinaison permettant la mise en oeuvre du procede
US6748797P 1997-12-01 1997-12-01
US6748897P 1997-12-01 1997-12-01
US60/067,488 1997-12-01
US60/067,487 1997-12-01
US8385898P 1998-05-01 1998-05-01
US97/08232 1998-05-01
US97/08233 1998-05-01
US60/083,858 1998-05-01
PCT/EP1998/003976 WO1999001175A1 (en) 1997-06-30 1998-06-30 Device for optimized electrotransfer of nucleic acid vectors to tissues in vivo

Publications (1)

Publication Number Publication Date
JP2002515816A true JP2002515816A (ja) 2002-05-28

Family

ID=27515625

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50807599A Pending JP2002515816A (ja) 1997-06-30 1998-06-30 ｉｎ ｖｉｖｏ組織に核酸ベクターを最適に電気導入する装置

Country Status (11)

Country Link
EP (1) EP0993318A1 (no)
JP (1) JP2002515816A (no)
KR (1) KR20010014298A (no)
CN (1) CN1261812A (no)
AU (1) AU8730798A (no)
BR (1) BR9810500A (no)
CA (1) CA2295029A1 (no)
IL (1) IL133709A0 (no)
NO (1) NO996540L (no)
PL (1) PL337617A1 (no)
WO (1) WO1999001175A1 (no)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007069679A1 (ja) * 2005-12-14 2007-06-21 Hisamitsu Pharmaceutical Co., Inc. イオントフォレーシス用デバイス
JP2009507786A (ja) * 2005-09-02 2009-02-26 ビオリアンス ファルマ 組織細胞内への核酸の電気的導入
JP2011528550A (ja) * 2008-07-18 2011-11-24 マックスサイト インコーポレーティッド 電気穿孔を最適化するための方法

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FR2753379B1 (fr) 1996-09-13 1998-10-30 Rhone Poulenc Rorer Sa Methode de traitement de la sclerose laterale amyotrophique
US6261281B1 (en) * 1997-04-03 2001-07-17 Electrofect As Method for genetic immunization and introduction of molecules into skeletal muscle and immune cells
CA2361601A1 (en) * 1999-02-08 2000-08-10 Cheryl Goldbeck Electrically-mediated enhancement of dna vaccine immunity and efficacy in vivo
WO2001068131A1 (en) 2000-03-13 2001-09-20 Cornell Research Foundation, Inc. Blocking leukocyte emigration and inflammation by interfering with cd99/hec2
JP2003531149A (ja) 2000-04-13 2003-10-21 ザ・ロツクフエラー・ユニバーシテイ 抗体由来の免疫応答の増強
JP2004532654A (ja) 2000-05-22 2004-10-28 マーク・アンド・カンパニー・インコーポレイテッド 薬剤投与システム性能評価システム及び方法
CN100422210C (zh) 2000-12-28 2008-10-01 Wyeth公司 来自肺炎链球菌的重组防护蛋白质
JP2005508134A (ja) 2001-03-02 2005-03-31 ザ ロックフェラー ユニヴァーシティ 天然アレルゲンの免疫原性を保持する、アレルゲン性が低下した組み換えハイブリッドアレルゲン構築体
US20020198567A1 (en) * 2001-06-07 2002-12-26 Yona Keisari Electro-endocytotic therapy as a treatment modality of cancer
MX339524B (es) 2001-10-11 2016-05-30 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
US20050154434A1 (en) 2002-03-07 2005-07-14 Adam Simon Clinical syringe with electrical stimulation aspects
US7217796B2 (en) 2002-05-24 2007-05-15 Schering Corporation Neutralizing human anti-IGFR antibody
US7785608B2 (en) 2002-08-30 2010-08-31 Wyeth Holdings Corporation Immunogenic compositions for the prevention and treatment of meningococcal disease
CA2624624C (en) * 2005-10-03 2016-07-19 Novocure Limited Optimizing characteristics of an electric field to increase the field's effect on proliferating cells
WO2008060814A2 (en) 2006-10-19 2008-05-22 Merck & Co., Inc. ANTI-IL-13Rα1 ANTIBODIES AND THEIR USES THEREOF
DK2068921T3 (da) 2006-10-19 2014-09-15 Csl Ltd Antistof-antagonister med høj affinitet af interleukin-13-receptor alpha 1
AR064642A1 (es) 2006-12-22 2009-04-15 Wyeth Corp Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
US8246176B2 (en) 2007-03-06 2012-08-21 Sanyo Electric Co., Ltd. Projection display device having an operation section for displacing a lens
US8093043B2 (en) 2008-06-04 2012-01-10 New York University β-TrCP1, β-TrCP2 and RSK1 or RSK2 inhibitors and methods for sensitizing target cells to apoptosis
MX2011004755A (es) 2008-11-05 2011-10-10 Wyeth Llc Composicion inmunogenica multicomponente para la prevencion de enfermedad estreptococica beta-hemolitica (bhs).
KR101594228B1 (ko) 2010-08-23 2016-02-15 와이어쓰 엘엘씨 네이세리아 메닌기티디스 ｒＬＰ２０８６ 항원의 안정한 제제
AU2011300409B2 (en) 2010-09-10 2015-03-26 Wyeth Llc Non-lipidated variants of Neisseria meningitidis ORF2086 antigens
KR101763625B1 (ko) 2012-03-09 2017-08-01 화이자 인코포레이티드 수막염균 조성물 및 이의 사용 방법
SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
WO2014107739A1 (en) 2013-01-07 2014-07-10 Eleven Biotherapeutics, Inc. Antibodies against pcsk9
US9802987B2 (en) 2013-03-08 2017-10-31 Pfizer Inc. Immunogenic fusion polypeptides
US9822150B2 (en) 2013-09-08 2017-11-21 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
KR20170103009A (ko) 2015-02-19 2017-09-12 화이자 인코포레이티드 나이세리아 메닌지티디스 조성물 및 그의 방법
PE20191107A1 (es) 2017-01-31 2019-08-26 Pfizer Composiciones de neisseria meningitidis y metodos respectivos

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9317380D0 (en) * 1993-08-20 1993-10-06 Therexsys Ltd Transfection process
US5641680A (en) * 1994-11-14 1997-06-24 Zhao; Xi Gene transfer apparatus and method for using the same
WO1997007826A1 (en) * 1995-08-29 1997-03-06 Cbr Laboratories, Inc. In vivo electroporation of cells

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009507786A (ja) * 2005-09-02 2009-02-26 ビオリアンス ファルマ 組織細胞内への核酸の電気的導入
WO2007069679A1 (ja) * 2005-12-14 2007-06-21 Hisamitsu Pharmaceutical Co., Inc. イオントフォレーシス用デバイス
JP2011528550A (ja) * 2008-07-18 2011-11-24 マックスサイト インコーポレーティッド 電気穿孔を最適化するための方法

Also Published As

Publication number Publication date
IL133709A0 (en) 2001-04-30
EP0993318A1 (en) 2000-04-19
PL337617A1 (en) 2000-08-28
NO996540D0 (no) 1999-12-29
CN1261812A (zh) 2000-08-02
BR9810500A (pt) 2000-09-05
AU8730798A (en) 1999-01-25
NO996540L (no) 2000-02-03
CA2295029A1 (en) 1999-01-14
WO1999001175A1 (en) 1999-01-14
KR20010014298A (ko) 2001-02-26

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