FR2765242B1 - Amelioration du transfert d'acide nucleique dans le muscle strie et combinaison permettant la mise en oeuvre du procede - Google Patents

Amelioration du transfert d'acide nucleique dans le muscle strie et combinaison permettant la mise en oeuvre du procede

Info

Publication number
FR2765242B1
FR2765242B1 FR9708233A FR9708233A FR2765242B1 FR 2765242 B1 FR2765242 B1 FR 2765242B1 FR 9708233 A FR9708233 A FR 9708233A FR 9708233 A FR9708233 A FR 9708233A FR 2765242 B1 FR2765242 B1 FR 2765242B1
Authority
FR
France
Prior art keywords
strike
muscle
implementation
improvement
transfer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9708233A
Other languages
English (en)
Other versions
FR2765242A1 (fr
Inventor
Michel Bureau
Lluis M Mir
Daniel Scherman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Gustave Roussy (IGR)
Original Assignee
Institut Gustave Roussy (IGR)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9708233A priority Critical patent/FR2765242B1/fr
Application filed by Institut Gustave Roussy (IGR) filed Critical Institut Gustave Roussy (IGR)
Priority to PL98337617A priority patent/PL337617A1/xx
Priority to PCT/FR1998/001400 priority patent/WO1999001158A1/fr
Priority to BR9810500-0A priority patent/BR9810500A/pt
Priority to PL98337583A priority patent/PL337583A1/xx
Priority to CZ0475599A priority patent/CZ299473B6/cs
Priority to KR1019997012430A priority patent/KR20010014298A/ko
Priority to HU0004589A priority patent/HUP0004589A3/hu
Priority to IL13371098A priority patent/IL133710A0/xx
Priority to PCT/EP1998/003976 priority patent/WO1999001175A1/fr
Priority to EP98935067A priority patent/EP0991426B2/fr
Priority to BR9810369-5A priority patent/BR9810369A/pt
Priority to CN98806793A priority patent/CN1261812A/zh
Priority to CA002294793A priority patent/CA2294793A1/fr
Priority to ZA985733A priority patent/ZA985733B/xx
Priority to DE69826124T priority patent/DE69826124T3/de
Priority to AT98935067T priority patent/ATE275423T1/de
Priority to CN98806671A priority patent/CN1261807A/zh
Priority to EP98938676A priority patent/EP0993318A1/fr
Priority to AU87307/98A priority patent/AU8730798A/en
Priority to IL13370998A priority patent/IL133709A0/xx
Priority to JP50807599A priority patent/JP2002515816A/ja
Priority to CA002295029A priority patent/CA2295029A1/fr
Priority to AU84447/98A priority patent/AU8444798A/en
Priority to JP50653099A priority patent/JP2002507985A/ja
Priority to KR1019997012481A priority patent/KR20010020571A/ko
Publication of FR2765242A1 publication Critical patent/FR2765242A1/fr
Priority to NO19996542A priority patent/NO328102B1/no
Priority to NO996540A priority patent/NO996540L/no
Application granted granted Critical
Publication of FR2765242B1 publication Critical patent/FR2765242B1/fr
Priority to US09/986,033 priority patent/US6939862B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/044—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
FR9708233A 1997-06-30 1997-06-30 Amelioration du transfert d'acide nucleique dans le muscle strie et combinaison permettant la mise en oeuvre du procede Expired - Lifetime FR2765242B1 (fr)

Priority Applications (29)

Application Number Priority Date Filing Date Title
FR9708233A FR2765242B1 (fr) 1997-06-30 1997-06-30 Amelioration du transfert d'acide nucleique dans le muscle strie et combinaison permettant la mise en oeuvre du procede
EP98938676A EP0993318A1 (fr) 1997-06-30 1998-06-30 Dispositif permettant un transfert in vivo optimise de vecteurs d'acides nucleiques dans des tissus
BR9810500-0A BR9810500A (pt) 1997-06-30 1998-06-30 Sistema e aparelho para a transferência de ácido nucléico in vivo para o interior de células de organismos eucarióticos pluricelulares
CN98806671A CN1261807A (zh) 1997-06-30 1998-06-30 向横纹肌中转移核酸的改进方法和用于实施该方法的组合
CZ0475599A CZ299473B6 (cs) 1997-06-30 1998-06-30 Nukleová kyselina a elektrické pole jako sdruženýprodukt pro prenos nukleové kyseliny do bunek prícne pruhovaného svalstva
KR1019997012430A KR20010014298A (ko) 1997-06-30 1998-06-30 핵산 벡터의 생체 내 조직으로의 적정화된 전기전달 장치
HU0004589A HUP0004589A3 (en) 1997-06-30 1998-06-30 Improved method for transferring nucleic acid into the striped muscle and combination therefor
PCT/FR1998/001400 WO1999001158A1 (fr) 1997-06-30 1998-06-30 Amelioration du transfert d'acide nucleique dans le muscle strie et combinaison permettant la mise en oeuvre du procede
PCT/EP1998/003976 WO1999001175A1 (fr) 1997-06-30 1998-06-30 Dispositif permettant un transfert in vivo optimise de vecteurs d'acides nucleiques dans des tissus
EP98935067A EP0991426B2 (fr) 1997-06-30 1998-06-30 Procede de transfert d'acide nucleique dans le muscle strie
BR9810369-5A BR9810369A (pt) 1997-06-30 1998-06-30 Processo de transferência de ácido nucleico para o interior de um ou mais músculos estriados, in vivo, composição, ácido mucleico e campo elétrico, e, produto de combinação
CN98806793A CN1261812A (zh) 1997-06-30 1998-06-30 用于向组织中体内进行核酸载体最佳电转移的装置
CA002294793A CA2294793A1 (fr) 1997-06-30 1998-06-30 Amelioration du transfert d'acide nucleique dans le muscle strie et combinaison permettant la mise en oeuvre du procede
AU87307/98A AU8730798A (en) 1997-06-30 1998-06-30 Device for optimized electrotransfer of nucleic acid vectors to tissues in vivo
PL98337617A PL337617A1 (en) 1997-06-30 1998-06-30 Apparatus for performing optimised in vivo electrotransfer of vectorial nucleic acids into tissues
AT98935067T ATE275423T1 (de) 1997-06-30 1998-06-30 Verabreichung der nukleinsäure in den quergestreiften muskel
PL98337583A PL337583A1 (en) 1997-06-30 1998-06-30 Improved method of transferring nucleic acid to a striated muscle and connection enabling accomplishment of this method
IL13371098A IL133710A0 (en) 1997-06-30 1998-06-30 Improved method for transferring nucleic acid into the striped muscle and combination thereof
ZA985733A ZA985733B (en) 1997-06-30 1998-06-30 The transfer of nucleic acid into the striated muscle and combination allowing the method to be carried out
IL13370998A IL133709A0 (en) 1997-06-30 1998-06-30 Device for optimized electrotransfer of nucleic acid vectors to tissues in vivo
JP50807599A JP2002515816A (ja) 1997-06-30 1998-06-30 ｉｎ ｖｉｖｏ組織に核酸ベクターを最適に電気導入する装置
CA002295029A CA2295029A1 (fr) 1997-06-30 1998-06-30 Dispositif permettant un transfert in vivo optimise de vecteurs d'acides nucleiques dans des tissus
AU84447/98A AU8444798A (en) 1997-06-30 1998-06-30 Improved method for transferring nucleic acid into the striped muscle and combination therefor
JP50653099A JP2002507985A (ja) 1997-06-30 1998-06-30 横紋筋に核酸を導入する改良法およびその組合せ
KR1019997012481A KR20010020571A (ko) 1997-06-30 1998-06-30 횡문근중으로 개선된 핵산 전달방법 및 이를 위한콤비네이션
DE69826124T DE69826124T3 (de) 1997-06-30 1998-06-30 Verabreichung der nukleinsäure in den quergestreiften muskel
NO19996542A NO328102B1 (no) 1997-06-30 1999-12-29 Kombinasjonsprodukt for overforing av nukleinsyre til muskel, samt anvendelse av nevnte kombinasjonsprodukt.
NO996540A NO996540L (no) 1997-06-30 1999-12-29 Innretning for optimalisert elektrooverfoering av nukleinsyrevektorer til vev in vivo
US09/986,033 US6939862B2 (en) 1997-06-30 2001-11-07 Method for transferring nucleic acid into striated muscles

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9708233A FR2765242B1 (fr) 1997-06-30 1997-06-30 Amelioration du transfert d'acide nucleique dans le muscle strie et combinaison permettant la mise en oeuvre du procede

Publications (2)

Publication Number Publication Date
FR2765242A1 FR2765242A1 (fr) 1998-12-31
FR2765242B1 true FR2765242B1 (fr) 2001-05-04

Family

ID=9508656

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9708233A Expired - Lifetime FR2765242B1 (fr) 1997-06-30 1997-06-30 Amelioration du transfert d'acide nucleique dans le muscle strie et combinaison permettant la mise en oeuvre du procede

Country Status (2)

Country Link
FR (1) FR2765242B1 (fr)
ZA (1) ZA985733B (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9317380D0 (en) * 1993-08-20 1993-10-06 Therexsys Ltd Transfection process
US5641680A (en) * 1994-11-14 1997-06-24 Zhao; Xi Gene transfer apparatus and method for using the same
WO1997007826A1 (fr) * 1995-08-29 1997-03-06 Cbr Laboratories, Inc. Electroporation in vivo de cellules

Also Published As

Publication number Publication date
FR2765242A1 (fr) 1998-12-31
ZA985733B (en) 1999-02-17

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