JP2002508767A5 - - Google Patents

Download PDF

Info

Publication number
JP2002508767A5
JP2002508767A5 JP1999505154A JP50515499A JP2002508767A5 JP 2002508767 A5 JP2002508767 A5 JP 2002508767A5 JP 1999505154 A JP1999505154 A JP 1999505154A JP 50515499 A JP50515499 A JP 50515499A JP 2002508767 A5 JP2002508767 A5 JP 2002508767A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1999505154A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002508767A (ja
JP4686696B2 (ja
Filing date
Publication date
Priority claimed from AUPO7550A external-priority patent/AUPO755097A0/en
Application filed filed Critical
Publication of JP2002508767A publication Critical patent/JP2002508767A/ja
Publication of JP2002508767A5 publication Critical patent/JP2002508767A5/ja
Application granted granted Critical
Publication of JP4686696B2 publication Critical patent/JP4686696B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP50515499A 1997-06-25 1998-06-25 C5a受容体およびGタンパク質結合受容体の環状アゴニストおよびアンタゴニスト Expired - Fee Related JP4686696B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AU7550 1997-06-25
AUPO7550A AUPO755097A0 (en) 1997-06-25 1997-06-25 Receptor agonist and antagonist
AUPO7550 1997-06-25
PCT/AU1998/000490 WO1999000406A1 (en) 1997-06-25 1998-06-25 CYCLIC AGONISTS AND ANTAGONISTS OF C5a RECEPTORS AND G PROTEIN-COUPLED RECEPTORS

Publications (3)

Publication Number Publication Date
JP2002508767A JP2002508767A (ja) 2002-03-19
JP2002508767A5 true JP2002508767A5 (enExample) 2006-09-21
JP4686696B2 JP4686696B2 (ja) 2011-05-25

Family

ID=3801840

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50515499A Expired - Fee Related JP4686696B2 (ja) 1997-06-25 1998-06-25 C5a受容体およびGタンパク質結合受容体の環状アゴニストおよびアンタゴニスト

Country Status (11)

Country Link
US (5) USRE41287E1 (enExample)
EP (1) EP1017713B1 (enExample)
JP (1) JP4686696B2 (enExample)
AT (1) ATE377606T1 (enExample)
AU (2) AUPO755097A0 (enExample)
CY (1) CY1107133T1 (enExample)
DE (1) DE69838678T2 (enExample)
DK (1) DK1017713T3 (enExample)
ES (1) ES2294816T3 (enExample)
PT (1) PT1017713E (enExample)
WO (1) WO1999000406A1 (enExample)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPO755097A0 (en) * 1997-06-25 1997-07-17 University Of Queensland, The Receptor agonist and antagonist
AUPQ339899A0 (en) 1999-10-13 1999-11-04 University Of Queensland, The Novel molecules
ES2353077T3 (es) 2000-08-10 2011-02-25 Mitsubishi Tanabe Pharma Corporation Derivados de urea con sustitución en posición 3 y uso medicinal de los mismos.
JP4751567B2 (ja) 2000-09-14 2011-08-17 田辺三菱製薬株式会社 新規アミド誘導体およびその医薬としての用途
AUPR833401A0 (en) * 2001-10-17 2001-11-08 University Of Queensland, The G protein-coupled receptor antagonists
ATE525391T1 (de) 2002-03-19 2011-10-15 Cincinnati Childrens S Hospital Medical Ct Muteine des c5a anaphylatoxins, für solche muteine kodierende nukleinsäuremoleküle, sowie pharmazeutische verwendungen von muteinen des c5a anaphylatoxins
WO2003084524A1 (en) * 2002-03-29 2003-10-16 Neurogen Corporation Combination therapy for the treatment of conditions with pathogenic inflammatory components
AUPS160602A0 (en) * 2002-04-08 2002-05-16 University Of Queensland, The Therapeutic method
AU2002950657A0 (en) 2002-08-08 2002-09-12 Alchemia Limited Derivatives of monosaccharides for drug discovery
AU2003266858B2 (en) * 2002-10-11 2006-09-14 Vast Bioscience Pty Limited Classes of compounds that interact with GPCRs
AU2002951995A0 (en) * 2002-10-11 2002-10-31 Alchemia Limited Classes of compounds that interact with gpcrs
AU2002952086A0 (en) * 2002-10-16 2002-11-07 The University Of Queensland Treatment of osteoarthritis
ATE509632T1 (de) * 2002-10-16 2011-06-15 Promics Pty Ltd Behandlung von entzündlicher darmerkrankung
AU2002952129A0 (en) * 2002-10-17 2002-10-31 The University Of Queensland Treatment of hypersensitivity conditions
AU2003902354A0 (en) * 2003-05-15 2003-05-29 Harkin, Denis W. Treatment of haemorrhagic shock
AU2003902586A0 (en) * 2003-05-26 2003-06-12 The University Of Queensland Treatment of burns
WO2005014849A2 (en) * 2003-07-03 2005-02-17 Euro-Celtique, S.A. Genes associated with responses to neuropathic pain
EP1498422A1 (de) 2003-07-17 2005-01-19 Jerini AG C5a-Rezeptor-Antagonisten
CA2579678A1 (en) * 2004-10-04 2006-04-13 Alchemia Limited Selective inhibitors
BRPI0606647A2 (pt) * 2005-01-17 2009-07-14 Jerini Ag antagonistas do receptor de c5a
EP1861114B1 (en) * 2005-03-11 2011-02-02 Potentia Pharmaceuticals, Inc. Compositions comprising modulators of g-protein-coupled receptor for treatment of macular degeneration
EP1739078A1 (de) 2005-05-30 2007-01-03 Jerini AG C5a-Rezeptor-Antagonisten
US20070292421A1 (en) * 2005-07-28 2007-12-20 Feinberg Bruce B Method for treating preeclampsia
US8168584B2 (en) 2005-10-08 2012-05-01 Potentia Pharmaceuticals, Inc. Methods of treating age-related macular degeneration by compstatin and analogs thereof
EP2148691B1 (en) 2007-02-05 2015-05-20 Apellis Pharmaceuticals, Inc. Compstatin analogues for use in the treatment of inflammatory conditions of the respiratory system
US20110092446A1 (en) * 2007-07-20 2011-04-21 Cedric Francois Compositions and methods for treatment of trauma
WO2009121065A2 (en) * 2008-03-28 2009-10-01 Apellis Ag Modulation and repletion/enhancement of the complement system for treatment of trauma
CN102165602A (zh) * 2008-07-02 2011-08-24 圣戈班性能塑料谢纳有限公司 带框器件、密封件及其制造方法
JP6223659B2 (ja) 2008-11-10 2017-11-01 アレクシオン ファーマシューティカルズ, インコーポレイテッド 補体関連障害を処置するための方法および組成物
US20130034568A1 (en) * 2010-01-22 2013-02-07 Georgios Hajishengallis Methods of treating or preventing periodontitis and diseases associated with periodontitis
AU2011245117B2 (en) 2010-04-30 2015-03-12 Alexion Pharmaceuticals, Inc. Anti-C5a antibodies and methods for using the antibodies
EP2588121A4 (en) * 2010-06-29 2013-12-04 Univ Nebraska C5A ANALOGUE AND USE METHOD THEREFOR
EP2468295A1 (en) * 2010-12-21 2012-06-27 Affiris AG Vaccines based on peptides of the complement protein C5a
CA2840270C (en) 2011-06-22 2023-09-26 Apellis Pharmaceuticals, Inc. Methods of treating chronic disorders with complement inhibitors
US9289467B2 (en) 2011-08-10 2016-03-22 Case Western Reserve University Compositions and methods for treating bone conditions
WO2014043223A1 (en) * 2012-09-11 2014-03-20 Hospital For Special Surgery Irhom2 inhibition for the treatment of complement mediated disorders
US10035822B2 (en) 2012-11-15 2018-07-31 Apellis Pharmaceuticals, Inc. Cell-reactive, long-acting, or targeted compstatin analogs and related compositions and methods
WO2014152391A1 (en) 2013-03-15 2014-09-25 Apellis Pharmaceuticals, Inc. Cell-penetrating compstatin analogs and uses thereof
US10092620B2 (en) * 2013-04-02 2018-10-09 The Scripps Research Institute Uses of cyclic peptides for treating and preventing atherosclerosis
AU2014306002B2 (en) 2013-08-07 2017-05-25 Alexion Pharmaceuticals, Inc. Atypical hemolytic uremic syndrome (aHUS) biomarker proteins
KR20180090785A (ko) 2015-10-07 2018-08-13 아펠리스 파마슈티컬스 인코포레이티드 투여 요법
MX2019001153A (es) 2016-07-29 2019-06-10 Pfizer Peptidos ciclicos como antagonistas del receptor c5a.
WO2018081400A1 (en) 2016-10-27 2018-05-03 Alexion Pharmaceuticals Inc. Assay for c5b-9 deposition in complement-associated disorders
DK3411400T3 (da) 2017-04-03 2021-10-11 Inflarx Gmbh Behandling af inflammatoriske sygdomme med hæmmere af c5a-aktivitet
BR112019020955A2 (pt) 2017-04-07 2020-05-05 Apellis Pharmaceuticals, Inc. regimes de dosagem e composições e métodos relacionados
AU2018286754A1 (en) 2017-06-23 2019-12-19 Inflarx Gmbh Treatment of inflammatory diseases with inhibitors of C5A activity
JP2021507884A (ja) 2017-12-15 2021-02-25 アペリス・ファーマシューティカルズ・インコーポレイテッドApellis Pharmaceuticals,Inc. 投与レジメンならびに関連組成物および方法
US20220356234A1 (en) 2019-10-02 2022-11-10 Alexion Pharmaceuticals, Inc. Complement inhibitors for treating drug-induced complement-mediated response
AU2020438234A1 (en) 2020-03-27 2022-09-29 Inflarx Gmbh Inhibitors of C5a for the treatment of corona virus infection
TW202208427A (zh) 2020-05-06 2022-03-01 德商因夫萊亞斯有限公司 人源化抗c5a抗體
CN115667925A (zh) 2020-05-15 2023-01-31 阿雷克森制药公司 使用细胞外囊泡来检测补体激活的方法以及其用于评估和/或监测补体介导的疾病的治疗的用途
WO2024238421A1 (en) 2023-05-12 2024-11-21 Alexion Pharmaceuticals, Inc. Use of biomarkers for the identification and treatment of complement-mediated disorders
WO2024238422A1 (en) 2023-05-12 2024-11-21 Alexion Pharmaceuticals, Inc. Use of a panel of lectins for detection of complement biomarkers in urine extracellular vesicles
US12180274B2 (en) 2023-05-26 2024-12-31 Inflarx Gmbh Treatment of pneumonia and ARDS with inhibitors of C5a and IL-6 activity

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5386011A (en) * 1990-12-27 1995-01-31 Abbott Laboratories Hexapeptide anaphylatoxin-receptor ligands
BR9408265A (pt) 1993-12-06 1996-12-10 Ciba Geigy Ag Antagonistas de receptor de c5a não tendo substancialmente nenhuma atividade de antagonista
US5807824A (en) 1993-12-06 1998-09-15 Ciba-Geigy Corporation C5A receptor antagonists having substantially no agonist activity
US5614370A (en) * 1994-03-18 1997-03-25 Merck & Co., Inc. Assay to identify human C5a antagonists and agonists
US5696230A (en) 1994-08-31 1997-12-09 The Board Of Regents Of The University Of Nebraska High-affinity response-selective C-terminal analogs of C5a anaphylatoxin
AUPO755097A0 (en) 1997-06-25 1997-07-17 University Of Queensland, The Receptor agonist and antagonist
AUPR833401A0 (en) 2001-10-17 2001-11-08 University Of Queensland, The G protein-coupled receptor antagonists
AUPS160602A0 (en) * 2002-04-08 2002-05-16 University Of Queensland, The Therapeutic method
AU2002952086A0 (en) * 2002-10-16 2002-11-07 The University Of Queensland Treatment of osteoarthritis

Similar Documents

Publication Publication Date Title
JP2000509942A5 (enExample)
JP2000507042A5 (enExample)
JP2000509912A5 (enExample)
JP2000509635A5 (enExample)
JP2000509637A5 (enExample)
JP2000510751A5 (enExample)
JP2001513006A5 (enExample)
JP2002501530A5 (enExample)
JP2000509587A5 (enExample)
JP2000507369A5 (enExample)
JP2000508866A5 (enExample)
JP2000510793A5 (enExample)
JP2000508841A5 (enExample)
JP2000508680A5 (enExample)
JP2000511609A5 (enExample)
JP2000509853A5 (enExample)
JP2001508687A5 (enExample)
JP2000510969A5 (enExample)
JP2000508102A5 (enExample)
JP2000508836A5 (enExample)
JP2000509520A5 (enExample)
JP2000509818A5 (enExample)
JP2001524996A5 (enExample)
JP2000507434A5 (enExample)
JP2002501626A5 (enExample)