JP2002507132A - 創傷治癒における真皮鞘組織 - Google Patents
創傷治癒における真皮鞘組織Info
- Publication number
- JP2002507132A JP2002507132A JP54670198A JP54670198A JP2002507132A JP 2002507132 A JP2002507132 A JP 2002507132A JP 54670198 A JP54670198 A JP 54670198A JP 54670198 A JP54670198 A JP 54670198A JP 2002507132 A JP2002507132 A JP 2002507132A
- Authority
- JP
- Japan
- Prior art keywords
- cells
- tissue
- wound healing
- dermal
- wound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/60—Materials for use in artificial skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
- C12N5/0627—Hair cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Public Health (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Wood Science & Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Description
Claims (1)
- 【特許請求の範囲】 1.真皮鞘組織を含んでなる創傷治癒システム。 2.前記真皮鞘組織が、毛包の選択された部分に由来する請求項1に記載の創 傷治癒システム。 3.前記選択された部分が、毛包の下方3分の1である請求項2に記載の創傷 治癒システム。 4.前記真皮鞘組織が、毛包付近の環状に連なった細胞に由来する請求項1〜 3のいずれか一に記載の創傷治癒システム。 5.前記環状に連なった細胞が、毛包の真皮又は間葉領域に対して内側にある 環状に連なった細胞である請求項4に記載の創傷治癒システム。 6.前記真皮鞘組織が、α平滑筋アクチンに関して陽性に染色されることを特 徴とする請求項1〜5のいずれか一に記載の創傷治癒システム。 7.前記真皮鞘組織に、毛包由来の少なくとも1つの他の組織又は細胞タイプ を提供するか、又は、該組織又は該細胞タイプを組み合わせる請求項1〜6のい ずれか一に記載の創傷治癒システム。 8.前記他の組織又は細胞タイプが、真皮乳頭又はそれに由来する細胞を含む 請求項7に記載の創傷治癒システム。 9.前記システムが適当な基質材料を含む請求項1〜8のいずれか一に記載の 創傷治癒システム。 10.前記基質材料が、天然コラーゲン、又は、再構成されたコラーゲンから 構成されたコラーゲンゲル又は格子、又は、再構成されたコラーゲンの極めて複 雑な混合物を含む請求項9に記載の創傷治癒システム。 11.前記システムが前記基質が適用される材料のウェブをさらに含み、前記 真皮鞘組織を含む前記基質が前記ウェブに組み込まれるか、又は、前記ウェブの 中に埋め込まれるか、又は、前記ウェブに関連するか、又は、前記ウェブに接着 される請求項9又は10に記載の創傷治癒システム。 12.前記システムが、外科用包帯材を含む請求項11に記載の創傷治癒シス テム。 13.前記システムが、治療用組成物を含む請求項1〜11のいずれか一に記 載の創傷治癒システム。 14.前記システムが、少なくとも1種の選択された治療剤をさらに含む請求 項12又は13に記載の創傷治癒システム。 15.前記選択された治療剤が、抗菌性又は殺菌性を有する請求項14に記載 の創傷治癒システム。 16.前記治療剤が、麻酔性を有する請求項14に記載の創傷治癒システム。 17.前記治療用組成物が、局所適用に合うように改変された請求項13〜1 6のいずれか一に記載の創傷治癒システム。 18.前記治療用組成物が、注射による投与に合うように改変された請求項1 3〜16のいずれか一に記載の創傷治癒システム。 19.前記治療用組成物が、プラスター又は包帯に組み込まれるか、又は、プ ラスター又は包帯中に埋め込まれるか、又は、プラスター又は包帯に関連するか 、又は、プラスター又は包帯に接着される請求項13〜18のいずれか一に記載 の創傷治癒システム 20.真皮鞘組織及び/又はそれに由来する細胞を組込んだ適当な基質材料、 及び/又は、該組織及び/又は該細胞中に埋め込んだ適当な基質材料、及び/又 は、該組織及び/又は該細胞に関連した適当な基質材料、及び/又は、該組織及 び/又は該細胞と接着した適当な基質材料を含む外科用包帯剤。 21.真皮鞘組織を含んでなる薬剤。 22.真皮鞘組織及び/又はそれに由来する又は細胞を含んでなるin vitroの 創傷モデリングシステム。 23.前記真皮鞘組織が非自己組織に由来する請求項1〜22のいずれか一に記 載された創傷治癒システム、外科用包帯材、薬剤、又はin vitroの創傷モデリン グシステム。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9708692.0A GB9708692D0 (en) | 1997-04-30 | 1997-04-30 | Dermal sheath tissue and/or cells derived therefrom in wound healing |
GB9708692.0 | 1997-04-30 | ||
PCT/GB1998/001080 WO1998048860A1 (en) | 1997-04-30 | 1998-04-14 | Dermal sheath tissue in wound healing |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2002507132A true JP2002507132A (ja) | 2002-03-05 |
JP4567105B2 JP4567105B2 (ja) | 2010-10-20 |
Family
ID=10811544
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP54670198A Expired - Lifetime JP4567105B2 (ja) | 1997-04-30 | 1998-04-14 | 創傷治癒における真皮鞘組織 |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0980270B1 (ja) |
JP (1) | JP4567105B2 (ja) |
AT (1) | ATE255426T1 (ja) |
AU (1) | AU738028B2 (ja) |
BR (1) | BR9809351A (ja) |
CA (1) | CA2287507A1 (ja) |
DE (1) | DE69820254T2 (ja) |
ES (1) | ES2212285T3 (ja) |
GB (1) | GB9708692D0 (ja) |
WO (1) | WO1998048860A1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2011101648A (ja) * | 2002-06-05 | 2011-05-26 | Rolf Hoffmann | 毛包間葉系幹細胞およびその使用 |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2365376C (en) | 2000-12-21 | 2006-03-28 | Ethicon, Inc. | Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration |
US20040078090A1 (en) | 2002-10-18 | 2004-04-22 | Francois Binette | Biocompatible scaffolds with tissue fragments |
US8197837B2 (en) | 2003-03-07 | 2012-06-12 | Depuy Mitek, Inc. | Method of preparation of bioabsorbable porous reinforced tissue implants and implants thereof |
US8226715B2 (en) | 2003-06-30 | 2012-07-24 | Depuy Mitek, Inc. | Scaffold for connective tissue repair |
US10583220B2 (en) | 2003-08-11 | 2020-03-10 | DePuy Synthes Products, Inc. | Method and apparatus for resurfacing an articular surface |
US11395865B2 (en) | 2004-02-09 | 2022-07-26 | DePuy Synthes Products, Inc. | Scaffolds with viable tissue |
GB0916370D0 (en) | 2009-09-18 | 2009-10-28 | Avecia Biolog Ltd | Compositions |
SG11201506312TA (en) | 2013-02-12 | 2015-09-29 | Replicel Life Sciences Inc | Compositions and methods for treating and repairing tendons |
MX2015017095A (es) * | 2013-06-18 | 2016-04-06 | Replicel Life Sciences Inc | Composiciones y metodos para tratamiento de la piel. |
WO2015123477A1 (en) | 2014-02-12 | 2015-08-20 | Replicel Life Sciences Inc. | Compositions and methods for treating bone, joints and cartilage |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4458678A (en) * | 1981-10-26 | 1984-07-10 | Massachusetts Institute Of Technology | Cell-seeding procedures involving fibrous lattices |
GB8604360D0 (en) * | 1986-02-21 | 1986-03-26 | Univ Dundee | Stimulation of hair growth |
FR2612938B1 (fr) * | 1987-03-26 | 1989-06-23 | Cird | Procede d'obtention d'un equivalent de peau et equivalent de peau correspondant |
US5091173A (en) * | 1989-06-29 | 1992-02-25 | The University Of Dundee | Hair growth composition |
US5423778A (en) * | 1989-12-14 | 1995-06-13 | Elof Eriksson | System and method for transplantation of cells |
US5556783A (en) * | 1991-03-27 | 1996-09-17 | Trustees Of Univ. Of Penna | Methods of culturing and modulating the growth of hair follicular stem cells |
AU1829097A (en) * | 1996-01-18 | 1997-08-11 | Johnson & Johnson Consumer Products, Inc. | Methods for regenerating scarless skin and compositions used therein |
-
1997
- 1997-04-30 GB GBGB9708692.0A patent/GB9708692D0/en active Pending
-
1998
- 1998-04-14 AU AU70598/98A patent/AU738028B2/en not_active Ceased
- 1998-04-14 AT AT98917354T patent/ATE255426T1/de not_active IP Right Cessation
- 1998-04-14 JP JP54670198A patent/JP4567105B2/ja not_active Expired - Lifetime
- 1998-04-14 WO PCT/GB1998/001080 patent/WO1998048860A1/en active IP Right Grant
- 1998-04-14 EP EP98917354A patent/EP0980270B1/en not_active Expired - Lifetime
- 1998-04-14 DE DE69820254T patent/DE69820254T2/de not_active Expired - Lifetime
- 1998-04-14 CA CA002287507A patent/CA2287507A1/en not_active Abandoned
- 1998-04-14 ES ES98917354T patent/ES2212285T3/es not_active Expired - Lifetime
- 1998-04-14 BR BR9809351-7A patent/BR9809351A/pt not_active Application Discontinuation
Non-Patent Citations (10)
Title |
---|
JPN6009004155, Annals of Plastic Surgery, 1994, Vol.33,No.3, p290−294 * |
JPN6009004157, Journal of Investigative Dermatology, 1993, Vol.100,No.3, p229−236 * |
JPN6009004159, Journal of Investigative Dermatology, 1993, Vol.101,Suppl.1, p124S−129S * |
JPN6009004162, American Journal of Pathology, 1996, Vol.148,No.6, p1871−1885 * |
JPN6009004163, Journal of Cell Science, 1991, Vol.99, p627−636 * |
JPN6009004164, Journal of Investigative Dermatology, 1993, Vol.101,No.4, p577−583 * |
JPN6009004165, Journal of Investigative Dermatology, 1987, Vol.89,No.4, p369−379 * |
JPN6009004166, Journal of Investigative Dermatology, 1995, Vol.105,No.6, p844−850 * |
JPN6009004167, Transplantation, 1995, Vol.59,No.7, p1032−1038 * |
JPN6009004168, Journal of Investigative Dermatology, 1996, Vol.107,No.6, p804−807 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2011101648A (ja) * | 2002-06-05 | 2011-05-26 | Rolf Hoffmann | 毛包間葉系幹細胞およびその使用 |
JP2014012021A (ja) * | 2002-06-05 | 2014-01-23 | Trichoscience Innovations Inc | 毛包間葉系幹細胞およびその使用 |
JP2016073303A (ja) * | 2002-06-05 | 2016-05-12 | トリコサイエンス・イノヴェーションズ・インコーポレイテッド | 毛包間葉系幹細胞およびその使用 |
Also Published As
Publication number | Publication date |
---|---|
WO1998048860A1 (en) | 1998-11-05 |
BR9809351A (pt) | 2000-07-04 |
CA2287507A1 (en) | 1998-11-05 |
EP0980270A1 (en) | 2000-02-23 |
AU7059898A (en) | 1998-11-24 |
AU738028B2 (en) | 2001-09-06 |
ES2212285T3 (es) | 2004-07-16 |
DE69820254T2 (de) | 2004-12-16 |
DE69820254D1 (de) | 2004-01-15 |
GB9708692D0 (en) | 1997-06-18 |
ATE255426T1 (de) | 2003-12-15 |
JP4567105B2 (ja) | 2010-10-20 |
EP0980270B1 (en) | 2003-12-03 |
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