JP2002506984A - 検出方法 - Google Patents

検出方法

Info

Publication number
JP2002506984A
JP2002506984A JP2000536887A JP2000536887A JP2002506984A JP 2002506984 A JP2002506984 A JP 2002506984A JP 2000536887 A JP2000536887 A JP 2000536887A JP 2000536887 A JP2000536887 A JP 2000536887A JP 2002506984 A JP2002506984 A JP 2002506984A
Authority
JP
Japan
Prior art keywords
label
probe
capture
target polynucleotide
waveguide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000536887A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002506984A5 (enExample
Inventor
アーベル，アンドレアス
ジョーゼフ ベック，ジェームズ
エーラート，マルクス
オロシュラン，ペーテル
Original Assignee
ノバルティス アクチエンゲゼルシャフト
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ノバルティス アクチエンゲゼルシャフト filed Critical ノバルティス アクチエンゲゼルシャフト
Publication of JP2002506984A publication Critical patent/JP2002506984A/ja
Publication of JP2002506984A5 publication Critical patent/JP2002506984A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2000536887A 1998-03-19 1999-03-17 検出方法 Pending JP2002506984A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9805935.5A GB9805935D0 (en) 1998-03-19 1998-03-19 Organic compounds
GB9805935.5 1998-03-19
PCT/EP1999/001782 WO1999047705A1 (en) 1998-03-19 1999-03-17 Detection method

Publications (2)

Publication Number Publication Date
JP2002506984A true JP2002506984A (ja) 2002-03-05
JP2002506984A5 JP2002506984A5 (enExample) 2006-05-11

Family

ID=10828909

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000536887A Pending JP2002506984A (ja) 1998-03-19 1999-03-17 検出方法

Country Status (8)

Country Link
US (1) US20060188873A1 (enExample)
EP (1) EP1064406B1 (enExample)
JP (1) JP2002506984A (enExample)
AT (1) ATE272721T1 (enExample)
AU (1) AU3414599A (enExample)
DE (1) DE69919143T2 (enExample)
GB (1) GB9805935D0 (enExample)
WO (1) WO1999047705A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3448654B2 (ja) 2001-11-22 2003-09-22 北陸先端科学技術大学院大学長 バイオチップ、バイオチップアレイ、及びそれらを用いたスクリーニング方法
WO2007037282A1 (ja) * 2005-09-27 2007-04-05 Eisai R & D Management Co., Ltd. 微小粒子に自己集合体を形成させる方法及び標的分析物の検出方法

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003531372A (ja) * 2000-04-14 2003-10-21 ツェプトゼンス アクチエンゲゼルシャフト 励起フィールドを強化するための格子導波路構造及びその使用
EP1281063A1 (de) * 2000-05-06 2003-02-05 Zeptosens AG Gitter-wellenleiter-struktur für multianalytbestimmungen und deren verwendung
WO2002001194A1 (en) 2000-06-25 2002-01-03 Affymetrix, Inc. Optically active substrates
GB0106949D0 (en) * 2001-03-20 2001-05-09 Norchip As Detection of mycobacteria
JP2005519593A (ja) * 2002-01-18 2005-07-07 ユニバーシティ オブ ユタ リサーチ ファウンデーション 平面導波路を使用する１塩基多型の検出法
GB0507835D0 (en) * 2005-04-18 2005-05-25 Solexa Ltd Method and device for nucleic acid sequencing using a planar wave guide
KR20100025328A (ko) * 2008-08-27 2010-03-09 삼성전자주식회사 이중가닥 영역과 말단 단일가닥 영역을 포함하는 이중가닥 핵산 프로브가 고정된 마이크로어레이를 제조하는 방법
US8331751B2 (en) 2009-03-02 2012-12-11 mBio Diagnositcs, Inc. Planar optical waveguide with core of low-index-of-refraction interrogation medium
US9212995B2 (en) 2009-03-02 2015-12-15 Mbio Diagnostics, Inc. System and method for detecting multiple molecules in one assay
US9658222B2 (en) 2009-03-02 2017-05-23 Mbio Diagnostics, Inc. Planar waveguide based cartridges and associated methods for detecting target analyte
US8300993B2 (en) 2009-03-02 2012-10-30 Mbio Diagnostics, Inc. Waveguide with integrated lens
US9109793B2 (en) * 2009-07-20 2015-08-18 Crayola, Llc Illuminated display unit
TW201217783A (en) 2010-09-15 2012-05-01 Mbio Diagnostics Inc System and method for detecting multiple molecules in one assay
EP2843047B1 (en) 2012-02-27 2019-10-30 Toray Industries, Inc. Nucleic acid detection method
CA3126140A1 (en) * 2019-01-08 2020-07-16 Akoya Biosciences, Inc. Flexible detection systems

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4868105A (en) * 1985-12-11 1989-09-19 Chiron Corporation Solution phase nucleic acid sandwich assay
US5283174A (en) * 1987-09-21 1994-02-01 Gen-Probe, Incorporated Homogenous protection assay
US5200314A (en) * 1990-03-23 1993-04-06 Chiron Corporation Polynucleotide capture assay employing in vitro amplification
GB9119735D0 (en) * 1991-09-16 1991-10-30 Secr Defence Gene probe biosensor method
US5681697A (en) * 1993-12-08 1997-10-28 Chiron Corporation Solution phase nucleic acid sandwich assays having reduced background noise and kits therefor
WO1996035940A1 (en) * 1995-05-12 1996-11-14 Novartis Ag Sensor platform and method for the parallel detection of a plurality of analytes using evanescently excited luminescence
US5902724A (en) * 1996-07-12 1999-05-11 Tm Technologies, Inc. Signal amplification method
US5832165A (en) * 1996-08-28 1998-11-03 University Of Utah Research Foundation Composite waveguide for solid phase binding assays

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3448654B2 (ja) 2001-11-22 2003-09-22 北陸先端科学技術大学院大学長 バイオチップ、バイオチップアレイ、及びそれらを用いたスクリーニング方法
WO2007037282A1 (ja) * 2005-09-27 2007-04-05 Eisai R & D Management Co., Ltd. 微小粒子に自己集合体を形成させる方法及び標的分析物の検出方法

Also Published As

Publication number Publication date
WO1999047705A1 (en) 1999-09-23
DE69919143D1 (de) 2004-09-09
AU3414599A (en) 1999-10-11
EP1064406B1 (en) 2004-08-04
DE69919143T2 (de) 2005-08-11
ATE272721T1 (de) 2004-08-15
GB9805935D0 (en) 1998-05-13
US20060188873A1 (en) 2006-08-24
EP1064406A1 (en) 2001-01-03

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