ATE272721T1 - Nukleinsäure hybridisierung-testverfahren in lösung - Google Patents

Nukleinsäure hybridisierung-testverfahren in lösung

Info

Publication number
ATE272721T1
ATE272721T1 AT99915651T AT99915651T ATE272721T1 AT E272721 T1 ATE272721 T1 AT E272721T1 AT 99915651 T AT99915651 T AT 99915651T AT 99915651 T AT99915651 T AT 99915651T AT E272721 T1 ATE272721 T1 AT E272721T1
Authority
AT
Austria
Prior art keywords
nucleic acid
solution
test procedure
acid hybridization
hybridization test
Prior art date
Application number
AT99915651T
Other languages
German (de)
English (en)
Inventor
Andreas Abel
James Joseph Beck
Markus Ehrat
Peter Oroszlan
Original Assignee
Novartis Erfind Verwalt Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Erfind Verwalt Gmbh filed Critical Novartis Erfind Verwalt Gmbh
Application granted granted Critical
Publication of ATE272721T1 publication Critical patent/ATE272721T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT99915651T 1998-03-19 1999-03-17 Nukleinsäure hybridisierung-testverfahren in lösung ATE272721T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9805935.5A GB9805935D0 (en) 1998-03-19 1998-03-19 Organic compounds
PCT/EP1999/001782 WO1999047705A1 (en) 1998-03-19 1999-03-17 Detection method

Publications (1)

Publication Number Publication Date
ATE272721T1 true ATE272721T1 (de) 2004-08-15

Family

ID=10828909

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99915651T ATE272721T1 (de) 1998-03-19 1999-03-17 Nukleinsäure hybridisierung-testverfahren in lösung

Country Status (8)

Country Link
US (1) US20060188873A1 (enExample)
EP (1) EP1064406B1 (enExample)
JP (1) JP2002506984A (enExample)
AT (1) ATE272721T1 (enExample)
AU (1) AU3414599A (enExample)
DE (1) DE69919143T2 (enExample)
GB (1) GB9805935D0 (enExample)
WO (1) WO1999047705A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001262178A1 (en) * 2000-04-14 2001-10-30 Zeptosens Ag Grid-waveguide structure for reinforcing an excitation field and use thereof
US20030138208A1 (en) * 2000-05-06 2003-07-24 Michael Pawlak Grating optical waveguide structure for multi-analyte determinations and the use thereof
US7158224B2 (en) 2000-06-25 2007-01-02 Affymetrix, Inc. Optically active substrates
GB0106949D0 (en) * 2001-03-20 2001-05-09 Norchip As Detection of mycobacteria
JP3448654B2 (ja) 2001-11-22 2003-09-22 北陸先端科学技術大学院大学長 バイオチップ、バイオチップアレイ、及びそれらを用いたスクリーニング方法
JP2005519593A (ja) 2002-01-18 2005-07-07 ユニバーシティ オブ ユタ リサーチ ファウンデーション 平面導波路を使用する１塩基多型の検出法
GB0507835D0 (en) * 2005-04-18 2005-05-25 Solexa Ltd Method and device for nucleic acid sequencing using a planar wave guide
WO2007037282A1 (ja) * 2005-09-27 2007-04-05 Eisai R & D Management Co., Ltd. 微小粒子に自己集合体を形成させる方法及び標的分析物の検出方法
KR20100025328A (ko) * 2008-08-27 2010-03-09 삼성전자주식회사 이중가닥 영역과 말단 단일가닥 영역을 포함하는 이중가닥 핵산 프로브가 고정된 마이크로어레이를 제조하는 방법
US9212995B2 (en) 2009-03-02 2015-12-15 Mbio Diagnostics, Inc. System and method for detecting multiple molecules in one assay
US8331751B2 (en) 2009-03-02 2012-12-11 mBio Diagnositcs, Inc. Planar optical waveguide with core of low-index-of-refraction interrogation medium
US9658222B2 (en) 2009-03-02 2017-05-23 Mbio Diagnostics, Inc. Planar waveguide based cartridges and associated methods for detecting target analyte
US8300993B2 (en) 2009-03-02 2012-10-30 Mbio Diagnostics, Inc. Waveguide with integrated lens
US9109793B2 (en) * 2009-07-20 2015-08-18 Crayola, Llc Illuminated display unit
WO2012037369A1 (en) 2010-09-15 2012-03-22 Mbio Diagnostics, Inc. System and method for detecting multiple molecules in one assay
WO2013129457A1 (ja) 2012-02-27 2013-09-06 東レ株式会社 核酸の検出方法
EP3908826A4 (en) * 2019-01-08 2022-10-19 Akoya Biosciences, Inc. FLEXIBLE DETECTION SYSTEMS

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4868105A (en) * 1985-12-11 1989-09-19 Chiron Corporation Solution phase nucleic acid sandwich assay
US5283174A (en) * 1987-09-21 1994-02-01 Gen-Probe, Incorporated Homogenous protection assay
US5200314A (en) * 1990-03-23 1993-04-06 Chiron Corporation Polynucleotide capture assay employing in vitro amplification
GB9119735D0 (en) * 1991-09-16 1991-10-30 Secr Defence Gene probe biosensor method
US5681697A (en) * 1993-12-08 1997-10-28 Chiron Corporation Solution phase nucleic acid sandwich assays having reduced background noise and kits therefor
EP1890130A3 (en) * 1995-05-12 2008-02-27 Novartis AG Sensor platform for the parallel detection of a plurality of analytes using evanescently excited luminescenes
AU4040097A (en) * 1996-07-12 1998-02-09 Tm Technologies, Inc. Signal amplification method
US5832165A (en) * 1996-08-28 1998-11-03 University Of Utah Research Foundation Composite waveguide for solid phase binding assays

Also Published As

Publication number Publication date
EP1064406B1 (en) 2004-08-04
JP2002506984A (ja) 2002-03-05
DE69919143D1 (de) 2004-09-09
WO1999047705A1 (en) 1999-09-23
DE69919143T2 (de) 2005-08-11
EP1064406A1 (en) 2001-01-03
AU3414599A (en) 1999-10-11
GB9805935D0 (en) 1998-05-13
US20060188873A1 (en) 2006-08-24

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