JP2002506973A5 - - Google Patents
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- Publication number
- JP2002506973A5 JP2002506973A5 JP2000535930A JP2000535930A JP2002506973A5 JP 2002506973 A5 JP2002506973 A5 JP 2002506973A5 JP 2000535930 A JP2000535930 A JP 2000535930A JP 2000535930 A JP2000535930 A JP 2000535930A JP 2002506973 A5 JP2002506973 A5 JP 2002506973A5
- Authority
- JP
- Japan
- Prior art keywords
- lanthanide metal
- embedded image
- analyte
- chelate complex
- metal chelate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229910052747 lanthanoid Inorganic materials 0.000 description 20
- 150000002602 lanthanoids Chemical class 0.000 description 20
- 150000004697 chelate complex Chemical class 0.000 description 19
- 239000002738 chelating agent Substances 0.000 description 19
- 229910052751 metal Inorganic materials 0.000 description 17
- 239000002184 metal Substances 0.000 description 17
- 239000012491 analyte Substances 0.000 description 16
- 125000003118 aryl group Chemical group 0.000 description 9
- 239000003446 ligand Substances 0.000 description 9
- 0 C*/C1=N\C=*(/*)\C/C=C/*1*=C Chemical compound C*/C1=N\C=*(/*)\C/C=C/*1*=C 0.000 description 7
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 7
- 238000000034 method Methods 0.000 description 7
- 125000001931 aliphatic group Chemical group 0.000 description 6
- -1 europium ion Chemical class 0.000 description 6
- 125000000623 heterocyclic group Chemical group 0.000 description 6
- 239000002253 acid Substances 0.000 description 5
- ZADPBFCGQRWHPN-UHFFFAOYSA-N boronic acid Chemical compound OBO ZADPBFCGQRWHPN-UHFFFAOYSA-N 0.000 description 5
- NLMDJJTUQPXZFG-UHFFFAOYSA-N 1,4,10,13-tetraoxa-7,16-diazacyclooctadecane Chemical compound C1COCCOCCNCCOCCOCCN1 NLMDJJTUQPXZFG-UHFFFAOYSA-N 0.000 description 3
- QBPPRVHXOZRESW-UHFFFAOYSA-N 1,4,7,10-tetraazacyclododecane Chemical compound C1CNCCNCCNCCN1 QBPPRVHXOZRESW-UHFFFAOYSA-N 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- 229910052693 Europium Inorganic materials 0.000 description 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
- 229910052771 Terbium Inorganic materials 0.000 description 3
- 150000001299 aldehydes Chemical class 0.000 description 3
- 150000001335 aliphatic alkanes Chemical class 0.000 description 3
- 125000002009 alkene group Chemical group 0.000 description 3
- 125000003545 alkoxy group Chemical group 0.000 description 3
- 150000001408 amides Chemical class 0.000 description 3
- 150000001412 amines Chemical group 0.000 description 3
- 125000002837 carbocyclic group Chemical group 0.000 description 3
- 239000002739 cryptand Substances 0.000 description 3
- 150000002085 enols Chemical class 0.000 description 3
- 150000002148 esters Chemical class 0.000 description 3
- 239000008103 glucose Substances 0.000 description 3
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 3
- 150000002576 ketones Chemical class 0.000 description 3
- 229910021645 metal ion Inorganic materials 0.000 description 3
- 150000002829 nitrogen Chemical class 0.000 description 3
- 150000003512 tertiary amines Chemical class 0.000 description 3
- AQLMHYSWFMLWBS-UHFFFAOYSA-N arsenite(1-) Chemical compound O[As](O)[O-] AQLMHYSWFMLWBS-UHFFFAOYSA-N 0.000 description 2
- 239000013110 organic ligand Substances 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 125000001424 substituent group Chemical group 0.000 description 2
- QLZHNIAADXEJJP-UHFFFAOYSA-N Phenylphosphonic acid Chemical compound OP(O)(=O)C1=CC=CC=C1 QLZHNIAADXEJJP-UHFFFAOYSA-N 0.000 description 1
- GCPXMJHSNVMWNM-UHFFFAOYSA-N arsenous acid Chemical group O[As](O)O GCPXMJHSNVMWNM-UHFFFAOYSA-N 0.000 description 1
- 125000005621 boronate group Chemical group 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3796098A | 1998-03-11 | 1998-03-11 | |
| US09/037,960 | 1998-03-11 | ||
| PCT/US1999/005290 WO1999046600A1 (en) | 1998-03-11 | 1999-03-11 | Detection of analytes by fluorescent lanthanide chelates |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002506973A JP2002506973A (ja) | 2002-03-05 |
| JP2002506973A5 true JP2002506973A5 (cg-RX-API-DMAC7.html) | 2006-04-27 |
| JP4625180B2 JP4625180B2 (ja) | 2011-02-02 |
Family
ID=21897295
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000535930A Expired - Fee Related JP4625180B2 (ja) | 1998-03-11 | 1999-03-11 | 被分析物の蛍光ランタニドキレートによる検出 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6344360B1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1062516A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP4625180B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR100718953B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN1159583C (cg-RX-API-DMAC7.html) |
| AU (1) | AU757901B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2322858C (cg-RX-API-DMAC7.html) |
| TW (1) | TWI227323B (cg-RX-API-DMAC7.html) |
| WO (1) | WO1999046600A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6766183B2 (en) | 1995-11-22 | 2004-07-20 | Medtronic Minimed, Inc. | Long wave fluorophore sensor compounds and other fluorescent sensor compounds in polymers |
| ATE278801T1 (de) | 1995-11-22 | 2004-10-15 | Medtronic Minimed Inc | Detektion von biologischen molekülen unter verwendung von chemischer amplifikation und optischem sensor |
| WO1998022820A1 (en) | 1996-11-21 | 1998-05-28 | Lawrence Livermore National Laboratory | Detection of biological molecules using boronate-based chemical amplification and optical sensors |
| TW495608B (en) | 1998-08-26 | 2002-07-21 | Sensors For Med & Science Inc | Optical-based sensing devices |
| FR2792072A1 (fr) * | 1999-04-08 | 2000-10-13 | Cis Bio Int | Methode homogene de detection ou de determination d'une interaction chimique ou physicochimique |
| US6673625B2 (en) | 1999-09-15 | 2004-01-06 | The Regents Of The University Of California | Saccharide sensing molecules having enhanced fluorescent properties |
| US6682938B1 (en) | 1999-09-15 | 2004-01-27 | The Regents Of The University Of California | Glucose sensing molecules having selected fluorescent properties |
| US6774102B1 (en) * | 1999-09-29 | 2004-08-10 | Gambro Dialysatoren Gmbh & Co. Kg | Extracorporeal endotoxin removal method |
| WO2001075450A2 (en) * | 2000-04-04 | 2001-10-11 | The Regents Of The University Of California | Fluorescent lifetime assays for non-invasive quantification of analytes |
| AU2001278145B2 (en) | 2000-08-04 | 2006-09-14 | Sensors For Medicine And Science, Inc. | Detection of analytes in aqueous environments |
| US7470420B2 (en) * | 2000-12-05 | 2008-12-30 | The Regents Of The University Of California | Optical determination of glucose utilizing boronic acid adducts |
| US6653141B2 (en) * | 2000-12-05 | 2003-11-25 | The Regents Of The University Of California | Polyhydroxyl-substituted organic molecule sensing method and device |
| US20020119581A1 (en) * | 2001-01-05 | 2002-08-29 | Daniloff George Y. | Detection of analytes |
| US6800451B2 (en) * | 2001-01-05 | 2004-10-05 | Sensors For Medicine And Science, Inc. | Detection of glucose in solutions also containing an alpha-hydroxy acid or a beta-diketone |
| US6927246B2 (en) | 2001-02-15 | 2005-08-09 | Medtronic Minimed, Inc. | Polymers functionalized with fluorescent boronate motifs and methods for making them |
| JP4729734B2 (ja) * | 2001-05-16 | 2011-07-20 | 財団法人北九州産業学術推進機構 | キドセンサによる重金属イオン測定装置 |
| US9493806B2 (en) | 2001-06-01 | 2016-11-15 | Colorado State University Research Foundation | Enzymatic biosensing systems |
| US9493805B2 (en) | 2001-06-01 | 2016-11-15 | Colorado State University Research Foundation | Enzymatic biosensors with enhanced activity retention for detection of organic compounds |
| WO2003002975A2 (en) * | 2001-06-27 | 2003-01-09 | The Uab Research Foundation | Biophotonic sensors and methods of use thereof |
| US20030215391A1 (en) * | 2001-07-19 | 2003-11-20 | Carlos Rabito | Fluorescent agents for real-time measurement of organ function |
| US7045361B2 (en) | 2001-09-12 | 2006-05-16 | Medtronic Minimed, Inc. | Analyte sensing via acridine-based boronate biosensors |
| ES2345194T3 (es) * | 2002-03-14 | 2010-09-17 | Sensors For Medicine And Science, Inc. | Deteccion de glucosa que tambien contienen un alfa hidroxiacido o una beta dicetona. |
| GB0210535D0 (en) * | 2002-05-08 | 2002-06-19 | Novartis Ag | Organic compounds |
| US7108659B2 (en) * | 2002-08-01 | 2006-09-19 | Healthetech, Inc. | Respiratory analyzer for exercise use |
| US20040106163A1 (en) * | 2002-11-12 | 2004-06-03 | Workman Jerome James | Non-invasive measurement of analytes |
| AU2003287735A1 (en) * | 2002-11-12 | 2004-06-03 | Argose, Inc. | Non-invasive measurement of analytes |
| JP4748791B2 (ja) * | 2003-02-24 | 2011-08-17 | 独立行政法人科学技術振興機構 | 蛍光性ランタニド錯体 |
| WO2005065241A2 (en) | 2003-12-24 | 2005-07-21 | Argose, Inc. | Smmr (small molecule metabolite reporters) for use as in vivo glucose biosensors |
| US7713745B2 (en) * | 2004-04-13 | 2010-05-11 | Sensors For Medicine And Science, Inc. | Non-covalent immobilization of indicator molecules |
| DE102004051830B4 (de) | 2004-10-25 | 2007-12-13 | Roche Diagnostics Gmbh | Multifunktionales Referenzsystem bei Analytbestimmungen durch Fluoreszenz |
| TWI381162B (zh) * | 2005-05-26 | 2013-01-01 | Plagenom Co Ltd | A authenticity determination method, an authenticity determination device, a authenticity determination system, and a detection device terminal |
| JP5057682B2 (ja) * | 2006-03-30 | 2012-10-24 | 株式会社東芝 | 照明装置、撮像装置及び携帯端末 |
| GB0613823D0 (en) | 2006-07-12 | 2006-08-23 | Univ Durham | Assay |
| US9796998B2 (en) | 2007-04-09 | 2017-10-24 | Colorado State University Research Foundation | Oxygenase-based biosensing systems for measurement of halogenated alkene concentrations |
| FR2917226B1 (fr) * | 2007-06-06 | 2009-09-11 | Inst Nat Sciences Appliq | Procede de marquage de materiaux a base de matrices organiques polymeriques thermoplastiques ou thermodurcissables |
| US20090247984A1 (en) * | 2007-10-24 | 2009-10-01 | Masimo Laboratories, Inc. | Use of microneedles for small molecule metabolite reporter delivery |
| CN102132145A (zh) * | 2008-07-28 | 2011-07-20 | 医药及科学传感器公司 | 用于分析物浓度的光学测量的系统和方法 |
| WO2010029735A1 (ja) * | 2008-09-10 | 2010-03-18 | 国立大学法人奈良先端科学技術大学院大学 | 構造解析装置、及び構造解析方法 |
| US10024797B2 (en) | 2010-11-22 | 2018-07-17 | Colorado State University Research Foundation | Biosensing systems for measurement of lactose |
| EP2685884B1 (en) | 2011-03-15 | 2020-09-23 | Senseonics, Incorporated | Integrated catalytic protection of oxidation sensitive materials |
| US9051598B2 (en) * | 2011-05-02 | 2015-06-09 | The Hong Kong University Of Science And Technology | Specific detection of D-glucose by a tetraphenylethene-base fluorescent sensor |
| WO2013019982A2 (en) | 2011-08-02 | 2013-02-07 | Colorado State University Research Foundation | Biosensing system with extended lifetime via cofactor recycling |
| WO2013160547A1 (en) | 2012-04-24 | 2013-10-31 | Haermae Harri | Method for characterizing and/or determining samples |
| US9194802B2 (en) | 2012-09-14 | 2015-11-24 | Regents Of The University Of Minnesota | Luminescent probes having a phenanthridinyl antenna, and methods of use |
| CN104955383B (zh) | 2012-12-28 | 2017-11-17 | 传感技术股份有限公司 | 用于氧化稳定性和光学稳定性的分析物可渗透的膜片系统 |
| KR101660399B1 (ko) * | 2013-08-23 | 2016-09-28 | 주식회사 메디센서 | 금 나노 입자를 포함하는 형광 입자 및 그 제조방법 |
| US9963556B2 (en) | 2013-09-18 | 2018-05-08 | Senseonics, Incorporated | Critical point drying of hydrogels in analyte sensors |
| FI125102B (en) * | 2013-11-19 | 2015-06-15 | Kemira Oyj | Method for the determination of an antifouling agent in a sample |
| FI125111B (en) * | 2013-11-19 | 2015-06-15 | Kemira Oyj | A method for analyzing a sample comprising first and second anticaking agents |
| CN103881128A (zh) * | 2014-03-10 | 2014-06-25 | 黄鹏 | 基于荧光检测方法的原位葡萄糖检测膜的制备方法 |
| EP3669175B1 (en) | 2017-08-14 | 2024-09-11 | Senseonics, Incorporated | Methods and systems for calculating analyte levels |
| EP3722379B1 (en) * | 2017-09-15 | 2023-10-11 | Dai Nippon Printing Co., Ltd. | Ink composition and printed matter |
| CN112047965B (zh) * | 2020-09-09 | 2022-04-26 | 黑龙江大学 | 一种具有激发态配体间质子转移特性的配合物的制备方法及应用 |
| CN115124731B (zh) * | 2022-08-12 | 2023-12-01 | 复旦大学 | 一种高值化豆科植物界面超组装SAFs荧光材料的制备方法 |
| CN118955414B (zh) * | 2024-10-17 | 2025-03-18 | 南昌大学 | 两亲性Eu配合物及其制备方法与在检测四环素中的应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4637988A (en) * | 1981-07-01 | 1987-01-20 | Eastman Kodak Company | Fluorescent labels for immunoassay |
| SE454115B (sv) * | 1982-09-13 | 1988-03-28 | Wallac Oy | Homogenfasanalys med lantanidkelat som merksubstans |
| JP2802921B2 (ja) * | 1986-06-17 | 1998-09-24 | マイクロスキャン、インコーポレイテッド | 蛍光バックグラウンド消去および水溶性希土類金属キレートフルオロフォルを使用する均質蛍光アッセイ |
| US5512246A (en) * | 1989-09-21 | 1996-04-30 | Anthony P. Russell | Method and means for detecting polyhydroxyl compounds |
| US5246867A (en) * | 1992-01-17 | 1993-09-21 | University Of Maryland At Baltimore | Determination and quantification of saccharides by luminescence lifetimes and energy transfer |
| GB2284809B (en) * | 1993-11-07 | 1998-04-29 | Japan Res Dev Corp | A fluorescent phenylboronic acid suitable for use in the detection of saccharides |
| US5631364A (en) * | 1994-03-31 | 1997-05-20 | Axis Biochemicals Asa | Labelled boronic acid derivatives |
| ATE278801T1 (de) * | 1995-11-22 | 2004-10-15 | Medtronic Minimed Inc | Detektion von biologischen molekülen unter verwendung von chemischer amplifikation und optischem sensor |
| JP2866043B2 (ja) * | 1995-12-21 | 1999-03-08 | 科学技術振興事業団 | カリックスアレーン誘導体 |
| US6001573A (en) * | 1996-06-14 | 1999-12-14 | Packard Bioscience B.V. | Use of porphyrins as a universal label |
-
1999
- 1999-03-11 EP EP99912403A patent/EP1062516A1/en not_active Ceased
- 1999-03-11 JP JP2000535930A patent/JP4625180B2/ja not_active Expired - Fee Related
- 1999-03-11 TW TW088103762A patent/TWI227323B/zh not_active IP Right Cessation
- 1999-03-11 AU AU30785/99A patent/AU757901B2/en not_active Ceased
- 1999-03-11 CN CNB998059862A patent/CN1159583C/zh not_active Expired - Fee Related
- 1999-03-11 US US09/265,979 patent/US6344360B1/en not_active Expired - Lifetime
- 1999-03-11 KR KR1020007010146A patent/KR100718953B1/ko not_active Expired - Fee Related
- 1999-03-11 WO PCT/US1999/005290 patent/WO1999046600A1/en not_active Ceased
- 1999-03-11 CA CA002322858A patent/CA2322858C/en not_active Expired - Fee Related
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