CN1159583C - 通过荧光镧系金属螯合物检测分析物 - Google Patents

通过荧光镧系金属螯合物检测分析物 Download PDF

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Publication number
CN1159583C
CN1159583C CNB998059862A CN99805986A CN1159583C CN 1159583 C CN1159583 C CN 1159583C CN B998059862 A CNB998059862 A CN B998059862A CN 99805986 A CN99805986 A CN 99805986A CN 1159583 C CN1159583 C CN 1159583C
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China
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analyte
fluorescence
identification unit
lanthanide
aryl
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Expired - Fee Related
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CNB998059862A
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English (en)
Chinese (zh)
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CN1300368A (zh
Inventor
埃德温・F・厄尔曼
埃德温·F·厄尔曼
大・V・尼古拉奇克
亚历山大·V·尼古拉奇克
Y・丹尼洛夫
乔治·Y·丹尼洛夫
帕克
戴维·帕克
E・科尔文
阿瑟·E·科尔文
托尔・G・卡利弗雷滕诺斯
阿里斯托尔·G·卡利弗雷滕诺斯
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Sensors for Medecine and Science Inc
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Sensors for Medecine and Science Inc
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    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/06—Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
    • Y10T436/144444—Glucose

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Materials Engineering (AREA)
  • Diabetes (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
CNB998059862A 1998-03-11 1999-03-11 通过荧光镧系金属螯合物检测分析物 Expired - Fee Related CN1159583C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3796098A 1998-03-11 1998-03-11
US09/037,960 1998-03-11

Publications (2)

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CN1300368A CN1300368A (zh) 2001-06-20
CN1159583C true CN1159583C (zh) 2004-07-28

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US (1) US6344360B1 (cg-RX-API-DMAC7.html)
EP (1) EP1062516A1 (cg-RX-API-DMAC7.html)
JP (1) JP4625180B2 (cg-RX-API-DMAC7.html)
KR (1) KR100718953B1 (cg-RX-API-DMAC7.html)
CN (1) CN1159583C (cg-RX-API-DMAC7.html)
AU (1) AU757901B2 (cg-RX-API-DMAC7.html)
CA (1) CA2322858C (cg-RX-API-DMAC7.html)
TW (1) TWI227323B (cg-RX-API-DMAC7.html)
WO (1) WO1999046600A1 (cg-RX-API-DMAC7.html)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6766183B2 (en) 1995-11-22 2004-07-20 Medtronic Minimed, Inc. Long wave fluorophore sensor compounds and other fluorescent sensor compounds in polymers
ATE278801T1 (de) 1995-11-22 2004-10-15 Medtronic Minimed Inc Detektion von biologischen molekülen unter verwendung von chemischer amplifikation und optischem sensor
WO1998022820A1 (en) 1996-11-21 1998-05-28 Lawrence Livermore National Laboratory Detection of biological molecules using boronate-based chemical amplification and optical sensors
TW495608B (en) 1998-08-26 2002-07-21 Sensors For Med & Science Inc Optical-based sensing devices
FR2792072A1 (fr) * 1999-04-08 2000-10-13 Cis Bio Int Methode homogene de detection ou de determination d'une interaction chimique ou physicochimique
US6673625B2 (en) 1999-09-15 2004-01-06 The Regents Of The University Of California Saccharide sensing molecules having enhanced fluorescent properties
US6682938B1 (en) 1999-09-15 2004-01-27 The Regents Of The University Of California Glucose sensing molecules having selected fluorescent properties
US6774102B1 (en) * 1999-09-29 2004-08-10 Gambro Dialysatoren Gmbh & Co. Kg Extracorporeal endotoxin removal method
WO2001075450A2 (en) * 2000-04-04 2001-10-11 The Regents Of The University Of California Fluorescent lifetime assays for non-invasive quantification of analytes
AU2001278145B2 (en) 2000-08-04 2006-09-14 Sensors For Medicine And Science, Inc. Detection of analytes in aqueous environments
US7470420B2 (en) * 2000-12-05 2008-12-30 The Regents Of The University Of California Optical determination of glucose utilizing boronic acid adducts
US6653141B2 (en) * 2000-12-05 2003-11-25 The Regents Of The University Of California Polyhydroxyl-substituted organic molecule sensing method and device
US20020119581A1 (en) * 2001-01-05 2002-08-29 Daniloff George Y. Detection of analytes
US6800451B2 (en) * 2001-01-05 2004-10-05 Sensors For Medicine And Science, Inc. Detection of glucose in solutions also containing an alpha-hydroxy acid or a beta-diketone
US6927246B2 (en) 2001-02-15 2005-08-09 Medtronic Minimed, Inc. Polymers functionalized with fluorescent boronate motifs and methods for making them
JP4729734B2 (ja) * 2001-05-16 2011-07-20 財団法人北九州産業学術推進機構 キドセンサによる重金属イオン測定装置
US9493806B2 (en) 2001-06-01 2016-11-15 Colorado State University Research Foundation Enzymatic biosensing systems
US9493805B2 (en) 2001-06-01 2016-11-15 Colorado State University Research Foundation Enzymatic biosensors with enhanced activity retention for detection of organic compounds
WO2003002975A2 (en) * 2001-06-27 2003-01-09 The Uab Research Foundation Biophotonic sensors and methods of use thereof
US20030215391A1 (en) * 2001-07-19 2003-11-20 Carlos Rabito Fluorescent agents for real-time measurement of organ function
US7045361B2 (en) 2001-09-12 2006-05-16 Medtronic Minimed, Inc. Analyte sensing via acridine-based boronate biosensors
ES2345194T3 (es) * 2002-03-14 2010-09-17 Sensors For Medicine And Science, Inc. Deteccion de glucosa que tambien contienen un alfa hidroxiacido o una beta dicetona.
GB0210535D0 (en) * 2002-05-08 2002-06-19 Novartis Ag Organic compounds
US7108659B2 (en) * 2002-08-01 2006-09-19 Healthetech, Inc. Respiratory analyzer for exercise use
US20040106163A1 (en) * 2002-11-12 2004-06-03 Workman Jerome James Non-invasive measurement of analytes
AU2003287735A1 (en) * 2002-11-12 2004-06-03 Argose, Inc. Non-invasive measurement of analytes
JP4748791B2 (ja) * 2003-02-24 2011-08-17 独立行政法人科学技術振興機構 蛍光性ランタニド錯体
WO2005065241A2 (en) 2003-12-24 2005-07-21 Argose, Inc. Smmr (small molecule metabolite reporters) for use as in vivo glucose biosensors
US7713745B2 (en) * 2004-04-13 2010-05-11 Sensors For Medicine And Science, Inc. Non-covalent immobilization of indicator molecules
DE102004051830B4 (de) 2004-10-25 2007-12-13 Roche Diagnostics Gmbh Multifunktionales Referenzsystem bei Analytbestimmungen durch Fluoreszenz
TWI381162B (zh) * 2005-05-26 2013-01-01 Plagenom Co Ltd A authenticity determination method, an authenticity determination device, a authenticity determination system, and a detection device terminal
JP5057682B2 (ja) * 2006-03-30 2012-10-24 株式会社東芝 照明装置、撮像装置及び携帯端末
GB0613823D0 (en) 2006-07-12 2006-08-23 Univ Durham Assay
US9796998B2 (en) 2007-04-09 2017-10-24 Colorado State University Research Foundation Oxygenase-based biosensing systems for measurement of halogenated alkene concentrations
FR2917226B1 (fr) * 2007-06-06 2009-09-11 Inst Nat Sciences Appliq Procede de marquage de materiaux a base de matrices organiques polymeriques thermoplastiques ou thermodurcissables
US20090247984A1 (en) * 2007-10-24 2009-10-01 Masimo Laboratories, Inc. Use of microneedles for small molecule metabolite reporter delivery
CN102132145A (zh) * 2008-07-28 2011-07-20 医药及科学传感器公司 用于分析物浓度的光学测量的系统和方法
WO2010029735A1 (ja) * 2008-09-10 2010-03-18 国立大学法人奈良先端科学技術大学院大学 構造解析装置、及び構造解析方法
US10024797B2 (en) 2010-11-22 2018-07-17 Colorado State University Research Foundation Biosensing systems for measurement of lactose
EP2685884B1 (en) 2011-03-15 2020-09-23 Senseonics, Incorporated Integrated catalytic protection of oxidation sensitive materials
US9051598B2 (en) * 2011-05-02 2015-06-09 The Hong Kong University Of Science And Technology Specific detection of D-glucose by a tetraphenylethene-base fluorescent sensor
WO2013019982A2 (en) 2011-08-02 2013-02-07 Colorado State University Research Foundation Biosensing system with extended lifetime via cofactor recycling
WO2013160547A1 (en) 2012-04-24 2013-10-31 Haermae Harri Method for characterizing and/or determining samples
US9194802B2 (en) 2012-09-14 2015-11-24 Regents Of The University Of Minnesota Luminescent probes having a phenanthridinyl antenna, and methods of use
CN104955383B (zh) 2012-12-28 2017-11-17 传感技术股份有限公司 用于氧化稳定性和光学稳定性的分析物可渗透的膜片系统
KR101660399B1 (ko) * 2013-08-23 2016-09-28 주식회사 메디센서 금 나노 입자를 포함하는 형광 입자 및 그 제조방법
US9963556B2 (en) 2013-09-18 2018-05-08 Senseonics, Incorporated Critical point drying of hydrogels in analyte sensors
FI125102B (en) * 2013-11-19 2015-06-15 Kemira Oyj Method for the determination of an antifouling agent in a sample
FI125111B (en) * 2013-11-19 2015-06-15 Kemira Oyj A method for analyzing a sample comprising first and second anticaking agents
CN103881128A (zh) * 2014-03-10 2014-06-25 黄鹏 基于荧光检测方法的原位葡萄糖检测膜的制备方法
EP3669175B1 (en) 2017-08-14 2024-09-11 Senseonics, Incorporated Methods and systems for calculating analyte levels
EP3722379B1 (en) * 2017-09-15 2023-10-11 Dai Nippon Printing Co., Ltd. Ink composition and printed matter
CN112047965B (zh) * 2020-09-09 2022-04-26 黑龙江大学 一种具有激发态配体间质子转移特性的配合物的制备方法及应用
CN115124731B (zh) * 2022-08-12 2023-12-01 复旦大学 一种高值化豆科植物界面超组装SAFs荧光材料的制备方法
CN118955414B (zh) * 2024-10-17 2025-03-18 南昌大学 两亲性Eu配合物及其制备方法与在检测四环素中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4637988A (en) * 1981-07-01 1987-01-20 Eastman Kodak Company Fluorescent labels for immunoassay
SE454115B (sv) * 1982-09-13 1988-03-28 Wallac Oy Homogenfasanalys med lantanidkelat som merksubstans
JP2802921B2 (ja) * 1986-06-17 1998-09-24 マイクロスキャン、インコーポレイテッド 蛍光バックグラウンド消去および水溶性希土類金属キレートフルオロフォルを使用する均質蛍光アッセイ
US5512246A (en) * 1989-09-21 1996-04-30 Anthony P. Russell Method and means for detecting polyhydroxyl compounds
US5246867A (en) * 1992-01-17 1993-09-21 University Of Maryland At Baltimore Determination and quantification of saccharides by luminescence lifetimes and energy transfer
GB2284809B (en) * 1993-11-07 1998-04-29 Japan Res Dev Corp A fluorescent phenylboronic acid suitable for use in the detection of saccharides
US5631364A (en) * 1994-03-31 1997-05-20 Axis Biochemicals Asa Labelled boronic acid derivatives
ATE278801T1 (de) * 1995-11-22 2004-10-15 Medtronic Minimed Inc Detektion von biologischen molekülen unter verwendung von chemischer amplifikation und optischem sensor
JP2866043B2 (ja) * 1995-12-21 1999-03-08 科学技術振興事業団 カリックスアレーン誘導体
US6001573A (en) * 1996-06-14 1999-12-14 Packard Bioscience B.V. Use of porphyrins as a universal label

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KR20010041855A (ko) 2001-05-25
AU757901B2 (en) 2003-03-13
US6344360B1 (en) 2002-02-05
CN1300368A (zh) 2001-06-20
CA2322858A1 (en) 1999-09-16
JP4625180B2 (ja) 2011-02-02
WO1999046600A1 (en) 1999-09-16
WO1999046600A9 (en) 1999-11-18
CA2322858C (en) 2009-06-02
KR100718953B1 (ko) 2007-05-16
TWI227323B (en) 2005-02-01
AU3078599A (en) 1999-09-27
EP1062516A1 (en) 2000-12-27
JP2002506973A (ja) 2002-03-05

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