JP2002029988A - 真皮コラーゲン線維束再構築剤及びそれを含有する組成物 - Google Patents
真皮コラーゲン線維束再構築剤及びそれを含有する組成物Info
- Publication number
- JP2002029988A JP2002029988A JP2000218808A JP2000218808A JP2002029988A JP 2002029988 A JP2002029988 A JP 2002029988A JP 2000218808 A JP2000218808 A JP 2000218808A JP 2000218808 A JP2000218808 A JP 2000218808A JP 2002029988 A JP2002029988 A JP 2002029988A
- Authority
- JP
- Japan
- Prior art keywords
- collagen fiber
- fiber bundle
- plant
- essence
- skin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000008186 Collagen Human genes 0.000 title claims abstract description 65
- 108010035532 Collagen Proteins 0.000 title claims abstract description 65
- 229920001436 collagen Polymers 0.000 title claims abstract description 65
- 239000000835 fiber Substances 0.000 title claims abstract description 63
- 239000003795 chemical substances by application Substances 0.000 title claims abstract description 39
- 239000000203 mixture Substances 0.000 title description 5
- 241000196324 Embryophyta Species 0.000 claims abstract description 33
- 230000037303 wrinkles Effects 0.000 claims abstract description 24
- 241000219926 Myrtaceae Species 0.000 claims abstract description 18
- 244000223014 Syzygium aromaticum Species 0.000 claims abstract description 7
- 235000016639 Syzygium aromaticum Nutrition 0.000 claims abstract description 7
- 239000002798 polar solvent Substances 0.000 claims abstract description 7
- 235000020030 perry Nutrition 0.000 claims abstract description 6
- 230000002500 effect on skin Effects 0.000 claims description 32
- 210000003491 skin Anatomy 0.000 claims description 31
- 210000004207 dermis Anatomy 0.000 claims description 28
- 238000002360 preparation method Methods 0.000 claims description 26
- 238000007634 remodeling Methods 0.000 claims description 19
- 235000013399 edible fruits Nutrition 0.000 claims description 2
- 238000000034 method Methods 0.000 claims 1
- 230000006872 improvement Effects 0.000 abstract description 5
- 230000002265 prevention Effects 0.000 abstract description 2
- 206010040954 Skin wrinkling Diseases 0.000 description 20
- 230000000694 effects Effects 0.000 description 18
- 239000000686 essence Substances 0.000 description 14
- -1 ethanol and methanol Chemical class 0.000 description 10
- 239000000047 product Substances 0.000 description 8
- 239000002537 cosmetic Substances 0.000 description 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 7
- 208000035475 disorder Diseases 0.000 description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
- 238000012360 testing method Methods 0.000 description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 5
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 5
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- 239000006210 lotion Substances 0.000 description 5
- 239000002904 solvent Substances 0.000 description 5
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 4
- 102000016942 Elastin Human genes 0.000 description 4
- 108010014258 Elastin Proteins 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 4
- 235000014113 dietary fatty acids Nutrition 0.000 description 4
- 229920002549 elastin Polymers 0.000 description 4
- 239000000194 fatty acid Substances 0.000 description 4
- 229930195729 fatty acid Natural products 0.000 description 4
- 230000007246 mechanism Effects 0.000 description 4
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 description 3
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 description 3
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 3
- 230000032683 aging Effects 0.000 description 3
- 239000000839 emulsion Substances 0.000 description 3
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- 235000011187 glycerol Nutrition 0.000 description 3
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- WCVRQHFDJLLWFE-UHFFFAOYSA-N pentane-1,2-diol Chemical compound CCCC(O)CO WCVRQHFDJLLWFE-UHFFFAOYSA-N 0.000 description 3
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- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
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- 229940119170 jojoba wax Drugs 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- TZIHFWKZFHZASV-UHFFFAOYSA-N methyl formate Chemical compound COC=O TZIHFWKZFHZASV-UHFFFAOYSA-N 0.000 description 2
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 2
- 239000004006 olive oil Substances 0.000 description 2
- 235000008390 olive oil Nutrition 0.000 description 2
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 102220240796 rs553605556 Human genes 0.000 description 2
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000001629 suppression Effects 0.000 description 2
- 230000000699 topical effect Effects 0.000 description 2
- WCGUUGGRBIKTOS-GPOJBZKASA-N (3beta)-3-hydroxyurs-12-en-28-oic acid Chemical compound C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CC[C@@H](C)[C@H](C)[C@H]5C4=CC[C@@H]3[C@]21C WCGUUGGRBIKTOS-GPOJBZKASA-N 0.000 description 1
- ALSTYHKOOCGGFT-KTKRTIGZSA-N (9Z)-octadecen-1-ol Chemical compound CCCCCCCC\C=C/CCCCCCCCO ALSTYHKOOCGGFT-KTKRTIGZSA-N 0.000 description 1
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- LEACJMVNYZDSKR-UHFFFAOYSA-N 2-octyldodecan-1-ol Chemical compound CCCCCCCCCCC(CO)CCCCCCCC LEACJMVNYZDSKR-UHFFFAOYSA-N 0.000 description 1
- GECRRQVLQHRVNH-MRCUWXFGSA-N 2-octyldodecyl (z)-octadec-9-enoate Chemical compound CCCCCCCCCCC(CCCCCCCC)COC(=O)CCCCCCC\C=C/CCCCCCCC GECRRQVLQHRVNH-MRCUWXFGSA-N 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- XPFCZYUVICHKDS-UHFFFAOYSA-N 3-methylbutane-1,3-diol Chemical compound CC(C)(O)CCO XPFCZYUVICHKDS-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- 208000004998 Abdominal Pain Diseases 0.000 description 1
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 235000014036 Castanea Nutrition 0.000 description 1
- 241001070941 Castanea Species 0.000 description 1
- 241000266331 Eugenia Species 0.000 description 1
- 208000031361 Hiccup Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 description 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
- 239000005642 Oleic acid Substances 0.000 description 1
- 239000004264 Petrolatum Substances 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- 108010073771 Soybean Proteins Proteins 0.000 description 1
- 235000021355 Stearic acid Nutrition 0.000 description 1
- ULUAUXLGCMPNKK-UHFFFAOYSA-N Sulfobutanedioic acid Chemical class OC(=O)CC(C(O)=O)S(O)(=O)=O ULUAUXLGCMPNKK-UHFFFAOYSA-N 0.000 description 1
- 244000045719 Syzygium Species 0.000 description 1
- 235000012096 Syzygium samarangense Nutrition 0.000 description 1
- 208000036029 Uterine contractions during pregnancy Diseases 0.000 description 1
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 239000006096 absorbing agent Substances 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000005215 alkyl ethers Chemical class 0.000 description 1
- 150000008051 alkyl sulfates Chemical class 0.000 description 1
- 239000002280 amphoteric surfactant Substances 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- BTFJIXJJCSYFAL-UHFFFAOYSA-N arachidyl alcohol Natural products CCCCCCCCCCCCCCCCCCCCO BTFJIXJJCSYFAL-UHFFFAOYSA-N 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 235000019437 butane-1,3-diol Nutrition 0.000 description 1
- 239000004203 carnauba wax Substances 0.000 description 1
- 235000013869 carnauba wax Nutrition 0.000 description 1
- 229940082483 carnauba wax Drugs 0.000 description 1
- 239000004359 castor oil Substances 0.000 description 1
- 235000019438 castor oil Nutrition 0.000 description 1
- 239000003093 cationic surfactant Substances 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 229920003086 cellulose ether Polymers 0.000 description 1
- 239000003240 coconut oil Substances 0.000 description 1
- 235000019864 coconut oil Nutrition 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 238000004440 column chromatography Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
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- 125000005131 dialkylammonium group Chemical group 0.000 description 1
- 229940008099 dimethicone Drugs 0.000 description 1
- 239000004205 dimethyl polysiloxane Substances 0.000 description 1
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 150000002170 ethers Chemical class 0.000 description 1
- 229960001617 ethyl hydroxybenzoate Drugs 0.000 description 1
- 235000010228 ethyl p-hydroxybenzoate Nutrition 0.000 description 1
- 239000004403 ethyl p-hydroxybenzoate Substances 0.000 description 1
- NUVBSKCKDOMJSU-UHFFFAOYSA-N ethylparaben Chemical compound CCOC(=O)C1=CC=C(O)C=C1 NUVBSKCKDOMJSU-UHFFFAOYSA-N 0.000 description 1
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- 150000004665 fatty acids Chemical class 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
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- 239000003349 gelling agent Substances 0.000 description 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
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- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
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- PLSAJKYPRJGMHO-UHFFFAOYSA-N ursolic acid Natural products CC1CCC2(CCC3(C)C(C=CC4C5(C)CCC(O)C(C)(C)C5CCC34C)C2C1C)C(=O)O PLSAJKYPRJGMHO-UHFFFAOYSA-N 0.000 description 1
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Landscapes
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000218808A JP2002029988A (ja) | 2000-07-19 | 2000-07-19 | 真皮コラーゲン線維束再構築剤及びそれを含有する組成物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000218808A JP2002029988A (ja) | 2000-07-19 | 2000-07-19 | 真皮コラーゲン線維束再構築剤及びそれを含有する組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002029988A true JP2002029988A (ja) | 2002-01-29 |
| JP2002029988A5 JP2002029988A5 (enExample) | 2007-06-21 |
Family
ID=18713706
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000218808A Pending JP2002029988A (ja) | 2000-07-19 | 2000-07-19 | 真皮コラーゲン線維束再構築剤及びそれを含有する組成物 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2002029988A (enExample) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002104921A (ja) * | 2000-09-29 | 2002-04-10 | Pola Chem Ind Inc | 真皮コラーゲン線維束再構築剤及びそれを含有する組成物 |
| JP2003183122A (ja) * | 2001-12-21 | 2003-07-03 | Ichimaru Pharcos Co Ltd | コラゲナーゼ活性阻害剤 |
| EP1454620A3 (en) * | 2003-03-06 | 2005-04-13 | Kao Corporation | Skin aging-preventing or improving agent |
| KR101354552B1 (ko) * | 2010-12-07 | 2014-01-23 | 한국생명공학연구원 | 데카스퍼뮴 프루티코숨 추출물을 유효성분으로 함유하는 노화방지용 조성물 |
| US8865208B2 (en) | 2007-05-29 | 2014-10-21 | Pola Chemical Industries Inc. | Vesicle useful for external preparation for skin, and external preparation for skin comprising the vesicle |
| JP2023127667A (ja) * | 2022-03-02 | 2023-09-14 | 株式会社ナリス化粧品 | ニトロ化タンパク質低減剤 |
Citations (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH069371A (ja) * | 1992-06-23 | 1994-01-18 | Mikimoto Pharmaceut Co Ltd | ヒアルロニダーゼ阻害剤 |
| JPH0624937A (ja) * | 1992-06-29 | 1994-02-01 | Narisu Keshohin:Kk | ムコ多糖類断片化抑制剤、活性酸素消去剤、抗酸化剤および化粧料。 |
| JPH0717847A (ja) * | 1993-06-30 | 1995-01-20 | Sansho Seiyaku Co Ltd | 皮膚外用剤 |
| JPH10130162A (ja) * | 1996-10-31 | 1998-05-19 | Kanebo Ltd | ヒアルロン酸分解阻害剤、ヒアルロン酸異常分解疾患治療剤および化粧料 |
| JPH115727A (ja) * | 1997-06-17 | 1999-01-12 | Pola Chem Ind Inc | 美肌用の化粧料 |
| JPH1112122A (ja) * | 1997-06-20 | 1999-01-19 | Pola Chem Ind Inc | 皮膚改善化粧料 |
| JPH11246385A (ja) * | 1998-03-03 | 1999-09-14 | Shiseido Co Ltd | 抗老化剤 |
| JPH11263720A (ja) * | 1998-03-13 | 1999-09-28 | Shiseido Co Ltd | 抗老化剤 |
| JPH11318387A (ja) * | 1989-10-31 | 1999-11-24 | Kanebo Ltd | 抗炎症用食品 |
| JP2000119125A (ja) * | 1998-10-06 | 2000-04-25 | Kao Corp | 皮膚老化防止・改善剤 |
| JP2000119189A (ja) * | 1998-10-06 | 2000-04-25 | Kao Corp | エラスターゼ阻害剤 |
| JP2000247897A (ja) * | 1999-02-26 | 2000-09-12 | Ichimaru Pharcos Co Ltd | 化粧料組成物 |
| JP2001058920A (ja) * | 1999-08-20 | 2001-03-06 | Kao Corp | 化粧料 |
| JP2001220312A (ja) * | 2000-02-09 | 2001-08-14 | Ichimaru Pharcos Co Ltd | 植物水蒸気蒸留水含有化粧料組成物 |
| JP2002003358A (ja) * | 2000-06-23 | 2002-01-09 | Shiseido Co Ltd | 皮膚外用剤 |
-
2000
- 2000-07-19 JP JP2000218808A patent/JP2002029988A/ja active Pending
Patent Citations (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11318387A (ja) * | 1989-10-31 | 1999-11-24 | Kanebo Ltd | 抗炎症用食品 |
| JPH069371A (ja) * | 1992-06-23 | 1994-01-18 | Mikimoto Pharmaceut Co Ltd | ヒアルロニダーゼ阻害剤 |
| JPH0624937A (ja) * | 1992-06-29 | 1994-02-01 | Narisu Keshohin:Kk | ムコ多糖類断片化抑制剤、活性酸素消去剤、抗酸化剤および化粧料。 |
| JPH0717847A (ja) * | 1993-06-30 | 1995-01-20 | Sansho Seiyaku Co Ltd | 皮膚外用剤 |
| JPH10130162A (ja) * | 1996-10-31 | 1998-05-19 | Kanebo Ltd | ヒアルロン酸分解阻害剤、ヒアルロン酸異常分解疾患治療剤および化粧料 |
| JPH115727A (ja) * | 1997-06-17 | 1999-01-12 | Pola Chem Ind Inc | 美肌用の化粧料 |
| JPH1112122A (ja) * | 1997-06-20 | 1999-01-19 | Pola Chem Ind Inc | 皮膚改善化粧料 |
| JPH11246385A (ja) * | 1998-03-03 | 1999-09-14 | Shiseido Co Ltd | 抗老化剤 |
| JPH11263720A (ja) * | 1998-03-13 | 1999-09-28 | Shiseido Co Ltd | 抗老化剤 |
| JP2000119125A (ja) * | 1998-10-06 | 2000-04-25 | Kao Corp | 皮膚老化防止・改善剤 |
| JP2000119189A (ja) * | 1998-10-06 | 2000-04-25 | Kao Corp | エラスターゼ阻害剤 |
| JP2000247897A (ja) * | 1999-02-26 | 2000-09-12 | Ichimaru Pharcos Co Ltd | 化粧料組成物 |
| JP2001058920A (ja) * | 1999-08-20 | 2001-03-06 | Kao Corp | 化粧料 |
| JP2001220312A (ja) * | 2000-02-09 | 2001-08-14 | Ichimaru Pharcos Co Ltd | 植物水蒸気蒸留水含有化粧料組成物 |
| JP2002003358A (ja) * | 2000-06-23 | 2002-01-09 | Shiseido Co Ltd | 皮膚外用剤 |
Non-Patent Citations (2)
| Title |
|---|
| 伊藤 三明 MITSUAKI ITO: "特集／最近の香粧品における新原料・新技術", FRAGRANCE JOURNAL VOL.22, NO.2, vol. 第22巻, JPN6010046606, ISSN: 0001704330 * |
| 田中浩 他: "活性酸素の培養ヒト皮膚線維芽細胞におけるコラーゲン代謝に及ぼす影響", 日本化粧品技術者会誌, vol. 28, no. 2, JPN6010046605, 1994, pages 172 - 177, ISSN: 0001704329 * |
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|---|---|---|---|---|
| JP2002104921A (ja) * | 2000-09-29 | 2002-04-10 | Pola Chem Ind Inc | 真皮コラーゲン線維束再構築剤及びそれを含有する組成物 |
| JP2003183122A (ja) * | 2001-12-21 | 2003-07-03 | Ichimaru Pharcos Co Ltd | コラゲナーゼ活性阻害剤 |
| EP1454620A3 (en) * | 2003-03-06 | 2005-04-13 | Kao Corporation | Skin aging-preventing or improving agent |
| US8865208B2 (en) | 2007-05-29 | 2014-10-21 | Pola Chemical Industries Inc. | Vesicle useful for external preparation for skin, and external preparation for skin comprising the vesicle |
| KR101354552B1 (ko) * | 2010-12-07 | 2014-01-23 | 한국생명공학연구원 | 데카스퍼뮴 프루티코숨 추출물을 유효성분으로 함유하는 노화방지용 조성물 |
| JP2023127667A (ja) * | 2022-03-02 | 2023-09-14 | 株式会社ナリス化粧品 | ニトロ化タンパク質低減剤 |
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