JP2001523723A5 - - Google Patents
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- Publication number
- JP2001523723A5 JP2001523723A5 JP2000521834A JP2000521834A JP2001523723A5 JP 2001523723 A5 JP2001523723 A5 JP 2001523723A5 JP 2000521834 A JP2000521834 A JP 2000521834A JP 2000521834 A JP2000521834 A JP 2000521834A JP 2001523723 A5 JP2001523723 A5 JP 2001523723A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- substance
- infection
- animal
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 description 14
- 239000000126 substance Substances 0.000 description 14
- 208000015181 infectious disease Diseases 0.000 description 10
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 8
- 241001465754 Metazoa Species 0.000 description 5
- 150000001875 compounds Chemical class 0.000 description 5
- 208000035473 Communicable disease Diseases 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 229910052739 hydrogen Inorganic materials 0.000 description 3
- 239000001257 hydrogen Substances 0.000 description 3
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 description 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 2
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 description 2
- 239000004599 antimicrobial Substances 0.000 description 2
- 125000004432 carbon atom Chemical group C* 0.000 description 2
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 description 1
- 208000002874 Acne Vulgaris Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241000192125 Firmicutes Species 0.000 description 1
- SQUHHTBVTRBESD-UHFFFAOYSA-N Hexa-Ac-myo-Inositol Natural products CC(=O)OC1C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O SQUHHTBVTRBESD-UHFFFAOYSA-N 0.000 description 1
- 208000032376 Lung infection Diseases 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 206010048685 Oral infection Diseases 0.000 description 1
- 208000005141 Otitis Diseases 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 description 1
- 229960001231 choline Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 208000019258 ear infection Diseases 0.000 description 1
- 150000004665 fatty acids Chemical group 0.000 description 1
- -1 hydrogen Chemical class 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 description 1
- 229960000367 inositol Drugs 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 235000015927 pasta Nutrition 0.000 description 1
- 201000001245 periodontitis Diseases 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 229940124531 pharmaceutical excipient Drugs 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 150000004671 saturated fatty acids Chemical class 0.000 description 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical group 0.000 description 1
- 239000006200 vaporizer Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6690197P | 1997-11-20 | 1997-11-20 | |
| US60/066,901 | 1997-11-20 | ||
| PCT/DK1998/000512 WO1999026632A1 (en) | 1997-11-20 | 1998-11-20 | Phospholipids having antimicrobial activity with or without the presence of antimicrobials |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001523723A JP2001523723A (ja) | 2001-11-27 |
| JP2001523723A5 true JP2001523723A5 (enExample) | 2006-01-19 |
Family
ID=22072448
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000521834A Pending JP2001523723A (ja) | 1997-11-20 | 1998-11-20 | 抗菌剤の存在下又は非存在下で抗菌活性を有するリン脂質 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6165997A (enExample) |
| EP (1) | EP1051180B1 (enExample) |
| JP (1) | JP2001523723A (enExample) |
| AT (1) | ATE216585T1 (enExample) |
| AU (1) | AU747288B2 (enExample) |
| CA (1) | CA2316340A1 (enExample) |
| DE (1) | DE69805100T2 (enExample) |
| DK (1) | DK1051180T3 (enExample) |
| ES (1) | ES2177089T3 (enExample) |
| NZ (1) | NZ505233A (enExample) |
| WO (1) | WO1999026632A1 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6861053B1 (en) | 1999-08-11 | 2005-03-01 | Cedars-Sinai Medical Center | Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth |
| US7048906B2 (en) | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
| DE69831609T2 (de) * | 1997-11-24 | 2006-02-02 | Zeng, Zhongming, Shenzhen | Pharmazeutische zusammensetzung zur stimulierung des wachstums von gram-positiven bazillen und zur erhöhung der azidität der vagina und ihre verwendung |
| GB9827865D0 (en) * | 1998-12-18 | 1999-02-10 | Woodcock Fiona | Medicament |
| US6838480B1 (en) * | 1999-05-28 | 2005-01-04 | Marie Madeline Wharton | Composition containing sucrafate and a topical anesthetic for humans and animals and method of use thereof |
| US6964949B2 (en) * | 2000-05-24 | 2005-11-15 | Shanghai Jiao Da Onlly Co., Ltd. | Pharmaceutical compositions for promoting the growth of gram-positive bacilli and increasing the acidity in the vagina and the use thereof |
| WO2002092104A1 (en) * | 2001-04-25 | 2002-11-21 | Biosynergen, Inc. | A pharmaceutical composition comprising lysophosphatidic acid |
| JP5051865B2 (ja) * | 2001-05-29 | 2012-10-17 | タケダ ファーマシューティカルズ ユー．エス．エー． インコーポレイティド | レシチンでのプロドラッグエステル非乳化調合物の経口バイオアベイラビリティの向上 |
| RU2259825C9 (ru) | 2001-06-18 | 2006-04-10 | БиоДием Лимитед | Вещества, проявляющие антимикробную, антигрибковую, антипротозойную активности |
| GB0201028D0 (en) * | 2002-01-17 | 2002-03-06 | Britannia Pharmaceuticals Ltd | Prevention of infectious diseases |
| ITMI20021280A1 (it) * | 2002-06-11 | 2003-12-11 | Carlo Ghisalberti | Metodo di trattamento anticellulite |
| US20050036972A1 (en) * | 2003-03-10 | 2005-02-17 | Hy-Gene Biomedical Corporation | System for managing pathogens and irritants and monitoring usage of anti-bacterial formulations |
| US20070049554A1 (en) * | 2005-08-29 | 2007-03-01 | Daniel Levine | Method for treatment or prevention of conditions caused by gram-positive bacteria |
| EP1869981A1 (de) * | 2006-06-21 | 2007-12-26 | Staatliches Weinbauinstitut Freiburg | Alkylphospholipide und Lyso-Phospholipide zur Bekämpfung von Pflanzenpathogenen |
| KR100870232B1 (ko) * | 2006-12-07 | 2008-11-24 | 재단법인서울대학교산학협력재단 | 치아용 미백기능성 물질 전달시스템 |
| JP5468385B2 (ja) * | 2007-11-02 | 2014-04-09 | ナガセケムテックス株式会社 | 抗真菌剤及び抗菌剤 |
| US20090149395A1 (en) * | 2007-12-10 | 2009-06-11 | Peoples Aaron | Novel macrocyclic polyene lactams |
| US9314524B2 (en) * | 2007-12-31 | 2016-04-19 | Calla Therapeutics Llc | Topical formulations of Flucytosine |
| KR20120129864A (ko) | 2009-08-21 | 2012-11-28 | 타겟티드 딜리버리 테크놀러지스 리미티드 | 소포성 제형 |
| US9693564B2 (en) * | 2011-06-21 | 2017-07-04 | Safehands Solutions, LLC | Water based antimicrobial composition using benzalkonium chloride and cocamidopropyl PG-dimonium chloride phosphate |
| KR101315483B1 (ko) * | 2011-06-23 | 2013-10-07 | 주식회사 아리바이오 | 항생제 및 라이소포스파티딜콜린을 포함하는 면역 증강 또는 세균성 감염 질환 치료용 조성물 |
| GB201205642D0 (en) | 2012-03-29 | 2012-05-16 | Sequessome Technology Holdings Ltd | Vesicular formulations |
| EP2805612A1 (en) | 2013-05-22 | 2014-11-26 | University of Graz | Lysophospholipids against American Foulbrood |
| US11660344B2 (en) * | 2013-11-17 | 2023-05-30 | Medrx Co., Ltd. | Transdermal colloidal solution agent |
| WO2015079532A1 (ja) * | 2013-11-28 | 2015-06-04 | キユーピー 株式会社 | 多剤耐性グラム陽性菌抗菌剤及び外用剤 |
| ES2895910T3 (es) | 2015-06-30 | 2022-02-23 | Sequessome Tech Holdings Limited | Composiciones multifásicas |
| US11413297B2 (en) | 2017-09-21 | 2022-08-16 | Avanti Polar Lipids, Llc | Therapies for treating and preventing chronic rhinosinusitis |
| KR102641583B1 (ko) * | 2018-10-23 | 2024-02-28 | 건국대학교 산학협력단 | 지도부딘을 포함하는 식물병 방제용 조성물 |
| WO2023111173A1 (en) * | 2021-12-16 | 2023-06-22 | INSERM (Institut National de la Santé et de la Recherche Médicale) | An ezh2 degrader or inhibitor for use in the treatment of resistant acute myeloid leukemia |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2185249A5 (enExample) * | 1972-05-15 | 1973-12-28 | Ibm | |
| JPS5318581B2 (enExample) * | 1974-03-12 | 1978-06-15 | ||
| JPS5233139A (en) * | 1975-09-08 | 1977-03-14 | Masakane Katayama | Automatic gas stop safety device with annunciator |
| JPS53118523A (en) * | 1977-03-23 | 1978-10-17 | Rikagaku Kenkyusho | Fungicides for agriculture and horticulture, and composition for controlling agents against fruit pests during storage |
| EP0088046B1 (de) * | 1982-02-17 | 1987-12-09 | Ciba-Geigy Ag | Lipide in wässriger Phase |
| US4588578A (en) * | 1983-08-08 | 1986-05-13 | The Liposome Company, Inc. | Lipid vesicles prepared in a monophase |
| CA1237670A (en) * | 1983-05-26 | 1988-06-07 | Andrew S. Janoff | Drug preparations of reduced toxicity |
| JPS6055564A (ja) * | 1983-09-06 | 1985-03-30 | Toshiba Corp | エラ−訂正回路 |
| US5135922A (en) * | 1984-06-15 | 1992-08-04 | Med-Tal, Inc. | Prevention and treatment of microbial infection by phosphoglycerides |
| US5409704A (en) * | 1985-06-26 | 1995-04-25 | The Liposome Company, Inc. | Liposomes comprising aminoglycoside phosphates and methods of production and use |
| JPS6216431A (ja) * | 1985-07-15 | 1987-01-24 | Nakanishi Michio | 医薬組成物 |
| US4923854A (en) * | 1986-01-22 | 1990-05-08 | The Liposome Company, Inc. | Solubilization of hydrophobic materials using lysophospholipid |
| JPH0774132B2 (ja) * | 1986-10-06 | 1995-08-09 | 旭電化工業株式会社 | 界面活性を有する静菌性組成物 |
| NZ223660A (en) * | 1987-03-05 | 1990-11-27 | Liposome Co Inc | Low toxicity drug-lipid complexes; methods of making them; and method of determining their toxicity |
| DE3852037T2 (de) * | 1987-07-29 | 1995-03-23 | Liposome Co Inc | Verfahren zur trennung von teilchen nach grösse. |
| US5466714A (en) * | 1987-12-31 | 1995-11-14 | Research Foundation For Mental Health Hygiene, Inc. | Spermicidal and cytocidal fatty acid compositions |
| US5434182A (en) * | 1987-12-31 | 1995-07-18 | Isaacs; Charles E. | Antibacterial fatty acid compositions |
| US5624958A (en) * | 1987-12-31 | 1997-04-29 | Isaacs; Charles E. | Disinfecting contact lenses |
| FR2636331B1 (fr) * | 1988-09-12 | 1990-11-16 | Bioeurope | Procede de preparation d'acides lysophosphatidiques et de sels de ceux-ci |
| US4999199A (en) * | 1988-11-10 | 1991-03-12 | Board Of Regents, The University Of Texas System | Pharmaceutical formulations: liposomes incorporating aromatic polyene antibiotics |
| JP2794072B2 (ja) * | 1989-09-29 | 1998-09-03 | 株式会社ヤクルト本社 | 抗菌剤 |
| DE69110906T2 (de) * | 1990-12-21 | 1995-11-16 | Hsc Research Dev Ltd Partnersh | Verwendung von Wirtszellphospholipiden zur Hemmung bakterieller Besiedlung. |
| IT1247165B (it) * | 1991-03-15 | 1994-12-12 | Fidia Spa | Uso terapeutico della fosfatidilserina e derivati in patologie degenerative anche associate a disfunsioni immunitarie. |
| US5648348A (en) * | 1991-10-28 | 1997-07-15 | Mona Industries, Inc. | Phospholipid antimicrobial compositions |
| WO1993008807A1 (en) * | 1991-10-28 | 1993-05-13 | Fost Dennis L | Phospholipid antimicrobial compositions |
| FR2683721B1 (fr) * | 1991-11-15 | 1995-06-09 | Inocosm Laboratoires | Composition lipidique polaire permettant de vehiculer un agent actif et/ou de le faire penetrer dans une cellule cible. |
| US5292513A (en) * | 1992-05-18 | 1994-03-08 | Anthony G. Gristina | Method for nonspecific cellular immune stimulation |
| JP2604940B2 (ja) * | 1992-05-19 | 1997-04-30 | 株式会社リケン | イオンプレーティング用蒸発材 |
| JP2809573B2 (ja) * | 1993-03-08 | 1998-10-08 | 科学技術振興事業団 | 新規リゾホスファチジルイノシトール及びその製造法 |
| US5478819A (en) * | 1993-06-23 | 1995-12-26 | Simo Tarpila | Phospholipid composition and use thereof |
| US5480877A (en) * | 1993-11-02 | 1996-01-02 | Wisconsin Alumni Research Foundation | Use of lysophosphatidic acids to enhance fibronectin binding |
| JPH07147953A (ja) * | 1993-11-29 | 1995-06-13 | Yakult Honsha Co Ltd | 抗菌剤及び抗菌剤の使用方法 |
| AU3333695A (en) * | 1994-05-31 | 1995-12-21 | David P. Franklin | Methods and products for the control of pathogenic bacteria |
| US5723136A (en) * | 1994-06-21 | 1998-03-03 | Institute For Advanced Skin Research, Inc. | Skin activator with glycosaminoglycan production-accelerating effect |
| FR2745184A1 (fr) * | 1996-02-28 | 1997-08-29 | Chanseau Sylvain | Utilisation de la lecithine de soja pour la preparation d' un medicament contre le sida |
-
1998
- 1998-11-19 US US09/196,354 patent/US6165997A/en not_active Expired - Fee Related
- 1998-11-20 AT AT98956826T patent/ATE216585T1/de active
- 1998-11-20 WO PCT/DK1998/000512 patent/WO1999026632A1/en not_active Ceased
- 1998-11-20 ES ES98956826T patent/ES2177089T3/es not_active Expired - Lifetime
- 1998-11-20 DK DK98956826T patent/DK1051180T3/da active
- 1998-11-20 CA CA002316340A patent/CA2316340A1/en not_active Abandoned
- 1998-11-20 DE DE69805100T patent/DE69805100T2/de not_active Expired - Lifetime
- 1998-11-20 AU AU13337/99A patent/AU747288B2/en not_active Ceased
- 1998-11-20 EP EP98956826A patent/EP1051180B1/en not_active Expired - Lifetime
- 1998-11-20 NZ NZ505233A patent/NZ505233A/en unknown
- 1998-11-20 JP JP2000521834A patent/JP2001523723A/ja active Pending
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