JP2001521765A - 特異的かつ高感度な核酸検出方法 - Google Patents
特異的かつ高感度な核酸検出方法Info
- Publication number
- JP2001521765A JP2001521765A JP2000519599A JP2000519599A JP2001521765A JP 2001521765 A JP2001521765 A JP 2001521765A JP 2000519599 A JP2000519599 A JP 2000519599A JP 2000519599 A JP2000519599 A JP 2000519599A JP 2001521765 A JP2001521765 A JP 2001521765A
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- nucleic acid
- probe
- sequence
- binding
- detected
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6823—Release of bound markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
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- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
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- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19748690.8 | 1997-11-04 | ||
| DE19748690A DE19748690A1 (de) | 1997-11-04 | 1997-11-04 | Spezifisches und sensitives Nukleinsäurenachweisverfahren |
| DE19814001A DE19814001A1 (de) | 1998-03-28 | 1998-03-28 | Spezifisches und sensitives Nukleinsäurenachweisverfahren |
| DE19814001.0 | 1998-03-28 | ||
| DE19814828.3 | 1998-04-02 | ||
| DE19814828A DE19814828A1 (de) | 1998-04-02 | 1998-04-02 | Spezifisches und sensitives Nukleinsäurenachweisverfahren |
| PCT/EP1998/006951 WO1999024606A2 (de) | 1997-11-04 | 1998-11-03 | Spezifisches und sensitives nukleinsäurenachweisverfahren |
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| JP2000519105A Pending JP2002505071A (ja) | 1997-11-04 | 1998-11-03 | 特異的かつ高感度な核酸検出方法 |
| JP2000519104A Pending JP2002509694A (ja) | 1997-11-04 | 1998-11-03 | 特異的かつ高感度な核酸検出方法 |
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| JP2000519105A Pending JP2002505071A (ja) | 1997-11-04 | 1998-11-03 | 特異的かつ高感度な核酸検出方法 |
| JP2000519104A Pending JP2002509694A (ja) | 1997-11-04 | 1998-11-03 | 特異的かつ高感度な核酸検出方法 |
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| US7569342B2 (en) | 1997-12-10 | 2009-08-04 | Sierra Molecular Corp. | Removal of molecular assay interferences |
| JP2002508190A (ja) * | 1997-12-12 | 2002-03-19 | ダイジーン・コーポレーション | 万能収集媒質 |
| US6361942B1 (en) | 1998-03-24 | 2002-03-26 | Boston Probes, Inc. | Method, kits and compositions pertaining to detection complexes |
| US7439016B1 (en) * | 2000-06-15 | 2008-10-21 | Digene Corporation | Detection of nucleic acids by type-specific hybrid capture method |
| US7601497B2 (en) | 2000-06-15 | 2009-10-13 | Qiagen Gaithersburg, Inc. | Detection of nucleic acids by target-specific hybrid capture method |
| US7807802B2 (en) | 2002-11-12 | 2010-10-05 | Abbott Lab | Polynucleotides for the amplification and detection of Chlamydia trachomatis and Neisseria gonorrhoeae |
| WO2008080029A2 (en) | 2006-12-21 | 2008-07-03 | Gen-Probe Incorporated | Methods and compositions for nucleic acid amplification |
| CN101680027A (zh) * | 2007-03-16 | 2010-03-24 | 454生命科学公司 | 检测hiv耐药变异体的系统和方法 |
| GB0714389D0 (en) | 2007-07-21 | 2007-09-05 | Barry Callebaut Ag | Process and product |
| US20090298187A1 (en) * | 2008-04-17 | 2009-12-03 | Qiagen Gaithersburg, Inc. | Compositions, methods, and kits using synthetic probes for determining the presence of a target nucleic acid |
| TWI394839B (zh) | 2008-10-27 | 2013-05-01 | Qiagen Gaithersburg Inc | 快速結果雜交捕捉法及系統 |
| JP6108661B2 (ja) * | 2009-01-28 | 2017-04-05 | キアジェン ゲイサーズバーグ インコーポレイテッド | 配列特異的な大量試料調製方法およびアッセイ法 |
| JP5738278B2 (ja) * | 2009-05-01 | 2015-06-24 | キアジェン ゲイサーズバーグ インコーポレイテッド | 試料中のｒｎａスプライシング形態を検出するための非標的増幅法 |
| EP2449132B1 (en) | 2009-07-01 | 2015-05-13 | Gen-Probe Incorporated | Methods and compositions for nucleic acid amplification |
| AU2010291990B2 (en) | 2009-09-14 | 2016-05-05 | Qiagen Gaithersburg, Inc. | Compositions and methods for recovery of nucleic acids or proteins from tissue samples fixed in cytology media |
| US9605303B2 (en) | 2010-01-29 | 2017-03-28 | Qiagen Gaithersburg, Inc. | Method of determining and confirming the presence of an HPV in a sample |
| EP2528932B1 (en) | 2010-01-29 | 2016-11-30 | QIAGEN Gaithersburg, Inc. | Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids |
| CA2799200A1 (en) | 2010-05-19 | 2011-11-24 | Qiagen Gaithersburg, Inc. | Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids |
| EP2576840B1 (en) | 2010-05-25 | 2018-10-17 | QIAGEN Gaithersburg, Inc. | Fast results hybrid capture assay and associated strategically-truncated probes |
| US9885092B2 (en) | 2011-02-24 | 2018-02-06 | Qiagen Gaithersburg Inc. | Materials and methods for detection of HPV nucleic acids |
| JP2024097096A (ja) * | 2021-04-28 | 2024-07-18 | バイオニクス株式会社 | 光学測定装置 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1190838A (en) * | 1981-07-17 | 1985-07-23 | Cavit Akin | Homogeneous nucleic acid hybridization diagnostics by non-radiative energy transfer |
| US5200313A (en) | 1983-08-05 | 1993-04-06 | Miles Inc. | Nucleic acid hybridization assay employing detectable anti-hybrid antibodies |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| AU606043B2 (en) * | 1985-03-28 | 1991-01-31 | F. Hoffmann-La Roche Ag | Detection of viruses by amplification and hybridization |
| ES286841Y (es) | 1985-05-20 | 1988-10-01 | Vileda Gmbh | Dispositivo de acoplamiento de un mango a un util de limpieza |
| CA1340807C (en) | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Nucleic acid amplification process |
| US5639871A (en) * | 1988-09-09 | 1997-06-17 | Roche Molecular Systems, Inc. | Detection of human papillomavirus by the polymerase chain reaction |
| ATE282716T1 (de) | 1989-07-11 | 2004-12-15 | Gen Probe Inc | Verfahren zur amplifikation von nukleinsäuresequenzen |
| NL9000134A (nl) * | 1990-01-19 | 1991-08-16 | Stichting Res Fonds Pathologie | Primers en werkwijze voor het detecteren van humaan papilloma virus genotypen m.b.v. pcr. |
| US5453355A (en) * | 1990-01-26 | 1995-09-26 | Abbott Laboratories | Oligonucleotides and methods for the detection of Neisseria gonorrhoeae |
| US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| CZ288720B6 (cs) * | 1991-05-08 | 2001-08-15 | Chiron Corporation | Nukleová kyselina, kompozice s jejím obsahem, způsob tvorby hybridizačního produktu a způsob detekce genotypů HCV |
| ES2111589T3 (es) | 1991-08-27 | 1998-03-16 | Hoffmann La Roche | Metodos y reactivos para la deteccion de la hepatitis c. |
| JPH05308999A (ja) * | 1992-05-08 | 1993-11-22 | Sumitomo Metal Ind Ltd | Ｂ型肝炎ウイルスｐｒｅ−Ｃ変異の判定法 |
| WO1994003635A1 (en) | 1992-08-04 | 1994-02-17 | Institute Of Molecular Biology & Biotechnology | Rapid amplification and detection of nucleic acids |
| US5605798A (en) * | 1993-01-07 | 1997-02-25 | Sequenom, Inc. | DNA diagnostic based on mass spectrometry |
| WO1995002690A1 (en) * | 1993-07-13 | 1995-01-26 | Abbott Laboratories | Nucleotide sequences and process for amplifying and detection of hepatitis b virus |
| US5538848A (en) * | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
| AT406019B (de) * | 1995-05-08 | 2000-01-25 | Immuno Ag | Verfahren zur herstellung eines arzneimittels enthaltend ein oder mehrere plasmaderivate |
| US5882857A (en) | 1995-06-07 | 1999-03-16 | Behringwerke Ag | Internal positive controls for nucleic acid amplification |
| AU726501B2 (en) | 1996-06-04 | 2000-11-09 | University Of Utah Research Foundation | Monitoring hybridization during PCR |
| US5858671A (en) | 1996-11-01 | 1999-01-12 | The University Of Iowa Research Foundation | Iterative and regenerative DNA sequencing method |
| US6333179B1 (en) * | 1997-06-20 | 2001-12-25 | Affymetrix, Inc. | Methods and compositions for multiplex amplification of nucleic acids |
| WO1999040226A2 (en) | 1998-02-04 | 1999-08-12 | Perkin-Elmer Corporation | Determination of a genotype of an amplification product at multiple allelic sites |
| US5948648A (en) | 1998-05-29 | 1999-09-07 | Khan; Shaheer H. | Nucleotide compounds including a rigid linker |
-
1998
- 1998-11-03 AU AU12320/99A patent/AU1232099A/en not_active Abandoned
- 1998-11-03 WO PCT/EP1998/006961 patent/WO1999023250A2/de not_active Ceased
- 1998-11-03 WO PCT/EP1998/006952 patent/WO1999023249A2/de not_active Ceased
- 1998-11-03 EP EP98965653A patent/EP1029084A2/de not_active Withdrawn
- 1998-11-03 CA CA002308762A patent/CA2308762A1/en not_active Abandoned
- 1998-11-03 JP JP2000519599A patent/JP2001521765A/ja active Pending
- 1998-11-03 AU AU21521/99A patent/AU741141B2/en not_active Ceased
- 1998-11-03 CA CA002308368A patent/CA2308368C/en not_active Expired - Fee Related
- 1998-11-03 JP JP2000519105A patent/JP2002505071A/ja active Pending
- 1998-11-03 WO PCT/EP1998/006951 patent/WO1999024606A2/de not_active Ceased
- 1998-11-03 EP EP98955529A patent/EP1029077A2/de not_active Ceased
- 1998-11-03 CA CA002312779A patent/CA2312779A1/en not_active Abandoned
- 1998-11-03 AU AU21520/99A patent/AU2152099A/en not_active Abandoned
- 1998-11-03 EP EP98965652A patent/EP1029083A2/de not_active Ceased
- 1998-11-03 JP JP2000519104A patent/JP2002509694A/ja active Pending
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2002
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Also Published As
| Publication number | Publication date |
|---|---|
| WO1999023250A2 (de) | 1999-05-14 |
| WO1999023249A2 (de) | 1999-05-14 |
| CA2308762A1 (en) | 1999-05-14 |
| EP1029084A2 (de) | 2000-08-23 |
| WO1999023250A3 (de) | 1999-07-22 |
| US7105318B2 (en) | 2006-09-12 |
| EP1029077A2 (de) | 2000-08-23 |
| CA2312779A1 (en) | 1999-05-20 |
| JP2002509694A (ja) | 2002-04-02 |
| WO1999024606A2 (de) | 1999-05-20 |
| CA2308368C (en) | 2009-01-20 |
| AU1232099A (en) | 1999-05-24 |
| AU2152199A (en) | 1999-05-24 |
| WO1999024606A3 (de) | 1999-07-22 |
| US20030175765A1 (en) | 2003-09-18 |
| JP2002505071A (ja) | 2002-02-19 |
| EP1029083A2 (de) | 2000-08-23 |
| AU741141B2 (en) | 2001-11-22 |
| CA2308368A1 (en) | 1999-05-14 |
| WO1999023249A3 (de) | 1999-09-10 |
| AU2152099A (en) | 1999-05-31 |
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