JP2001512823A - 自動化された生物反応システム - Google Patents
自動化された生物反応システムInfo
- Publication number
- JP2001512823A JP2001512823A JP2000506511A JP2000506511A JP2001512823A JP 2001512823 A JP2001512823 A JP 2001512823A JP 2000506511 A JP2000506511 A JP 2000506511A JP 2000506511 A JP2000506511 A JP 2000506511A JP 2001512823 A JP2001512823 A JP 2001512823A
- Authority
- JP
- Japan
- Prior art keywords
- valve
- fluid
- nozzle
- dispenser
- slide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- 239000003153 chemical reaction reagent Substances 0.000 claims description 204
- 239000007788 liquid Substances 0.000 claims description 153
- 238000000034 method Methods 0.000 claims description 114
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- 229910052751 metal Inorganic materials 0.000 description 5
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- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 3
- 229910052782 aluminium Inorganic materials 0.000 description 3
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- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 1
- RRLHMJHRFMHVNM-BQVXCWBNSA-N [(2s,3r,6r)-6-[5-[5-hydroxy-3-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxypentoxy]-2-methyl-3,6-dihydro-2h-pyran-3-yl] acetate Chemical compound C1=C[C@@H](OC(C)=O)[C@H](C)O[C@H]1OCCCCCOC1=CC(O)=C2C(=O)C(C=3C=CC(O)=CC=3)=COC2=C1 RRLHMJHRFMHVNM-BQVXCWBNSA-N 0.000 description 1
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- HQQADJVZYDDRJT-UHFFFAOYSA-N ethene;prop-1-ene Chemical group C=C.CC=C HQQADJVZYDDRJT-UHFFFAOYSA-N 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1016—Control of the volume dispensed or introduced
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
- G01N1/312—Apparatus therefor for samples mounted on planar substrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00871—Communications between instruments or with remote terminals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1002—Reagent dispensers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
- G01N2001/317—Apparatus therefor spraying liquids onto surfaces
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00871—Communications between instruments or with remote terminals
- G01N2035/00881—Communications between instruments or with remote terminals network configurations
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1034—Transferring microquantities of liquid
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/7722—Line condition change responsive valves
- Y10T137/7837—Direct response valves [i.e., check valve type]
- Y10T137/7869—Biased open
- Y10T137/7871—Weight biased
- Y10T137/7873—Ball valves
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/112499—Automated chemical analysis with sample on test slide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/909,335 US6093574A (en) | 1997-08-11 | 1997-08-11 | Method and apparatus for rinsing a microscope slide |
| US08/909,335 | 1997-08-11 | ||
| US08/995,052 | 1997-12-19 | ||
| US08/995,052 US6045759A (en) | 1997-08-11 | 1997-12-19 | Fluid dispenser |
| PCT/US1998/016604 WO1999008090A1 (en) | 1997-08-11 | 1998-08-11 | Automated biological reaction system |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008164174A Division JP4354000B2 (ja) | 1997-08-11 | 2008-06-24 | 自動化された生物反応システム |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001512823A true JP2001512823A (ja) | 2001-08-28 |
| JP2001512823A5 JP2001512823A5 (enExample) | 2006-01-05 |
Family
ID=27129520
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000506511A Pending JP2001512823A (ja) | 1997-08-11 | 1998-08-11 | 自動化された生物反応システム |
| JP2008164174A Expired - Lifetime JP4354000B2 (ja) | 1997-08-11 | 2008-06-24 | 自動化された生物反応システム |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008164174A Expired - Lifetime JP4354000B2 (ja) | 1997-08-11 | 2008-06-24 | 自動化された生物反応システム |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US6045759A (enExample) |
| EP (1) | EP1004013B1 (enExample) |
| JP (2) | JP2001512823A (enExample) |
| AU (1) | AU8826198A (enExample) |
| CA (1) | CA2301286C (enExample) |
| WO (1) | WO1999008090A1 (enExample) |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007086080A (ja) * | 2005-09-23 | 2007-04-05 | Ventana Medical Syst Inc | 自動式生物学的反応装置用試薬管理システム |
| JP2007517199A (ja) * | 2003-12-22 | 2007-06-28 | ベンタナ・メデイカル・システムズ・インコーポレーテツド | 流体ディスペンサー |
| JP2008504532A (ja) * | 2004-06-24 | 2008-02-14 | バイエル・ヘルスケア・エルエルシー | カートリッジおよびセンサ分与機器 |
| US7744817B2 (en) | 2003-08-11 | 2010-06-29 | Sakura Finetek U.S.A., Inc. | Manifold assembly |
| US7767152B2 (en) | 2003-08-11 | 2010-08-03 | Sakura Finetek U.S.A., Inc. | Reagent container and slide reaction retaining tray, and method of operation |
| JP2013068612A (ja) * | 2011-09-21 | 2013-04-18 | Sakura Finetex Usa Inc | 自動染色システムおよび反応チャンバ |
| US8459509B2 (en) | 2006-05-25 | 2013-06-11 | Sakura Finetek U.S.A., Inc. | Fluid dispensing apparatus |
| US8580568B2 (en) | 2011-09-21 | 2013-11-12 | Sakura Finetek U.S.A., Inc. | Traceability for automated staining system |
| US8609023B1 (en) | 1997-08-11 | 2013-12-17 | Ventana Medical Systems, Inc. | Memory management method and apparatus for automated biological reaction system |
| US8752732B2 (en) | 2011-02-01 | 2014-06-17 | Sakura Finetek U.S.A., Inc. | Fluid dispensing system |
| JP2014522489A (ja) * | 2011-06-01 | 2014-09-04 | ベンタナ メディカル システムズ， インコーポレイテッド | フィルタデバイスを備えるディスペンサ |
| JP2021507200A (ja) * | 2017-12-21 | 2021-02-22 | ライカ・バイオシステムズ・メルボルン・プロプライエタリー・リミテッドＬｅｉｃａ Ｂｉｏｓｙｓｔｅｍｓ Ｍｅｌｂｏｕｒｎｅ Ｐｔｙ Ｌｔｄ | 流体輸送システム |
Families Citing this family (81)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5595707A (en) * | 1990-03-02 | 1997-01-21 | Ventana Medical Systems, Inc. | Automated biological reaction apparatus |
| US6735531B2 (en) | 1996-10-07 | 2004-05-11 | Lab Vision Corporation | Method and apparatus for automatic tissue staining |
| US20050135972A1 (en) * | 1997-08-11 | 2005-06-23 | Ventana Medical Systems, Inc. | Method and apparatus for modifying pressure within a fluid dispenser |
| US20020110494A1 (en) * | 2000-01-14 | 2002-08-15 | Ventana Medical Systems, Inc. | Method and apparatus for modifying pressure within a fluid dispenser |
| US6045759A (en) * | 1997-08-11 | 2000-04-04 | Ventana Medical Systems | Fluid dispenser |
| IL121968A0 (en) * | 1997-10-14 | 1998-03-10 | A R T Medical Instr Ltd | Method for depositing a microvolume of liquid on a surface and apparatus therefor and a microvolume pump therefor |
| US6537505B1 (en) * | 1998-02-20 | 2003-03-25 | Bio Dot, Inc. | Reagent dispensing valve |
| US6183693B1 (en) * | 1998-02-27 | 2001-02-06 | Cytologix Corporation | Random access slide stainer with independent slide heating regulation |
| US6620620B1 (en) * | 1998-04-27 | 2003-09-16 | Era Systems, Inc. | Micro liquid evaporator |
| US6403036B1 (en) | 1999-09-29 | 2002-06-11 | Ventana Medical Systems, Inc. | Temperature monitoring system for an automated biological reaction apparatus |
| US6902702B1 (en) * | 2000-08-16 | 2005-06-07 | University Health Network | Devices and methods for producing microarrays of biological samples |
| US20020106812A1 (en) * | 2001-01-26 | 2002-08-08 | Fisher William D. | Fluid drop dispensing |
| US6485918B1 (en) | 2001-07-02 | 2002-11-26 | Packard Bioscience Corporation | Method and apparatus for incubation of a liquid reagent and target spots on a microarray substrate |
| AU2002361618A1 (en) * | 2001-11-13 | 2003-05-26 | Chromavision Medical Systems, Inc. | A system for tracking biological samples |
| US6998270B2 (en) * | 2001-11-26 | 2006-02-14 | Lab Vision Corporation | Automated tissue staining system and reagent container |
| US20040033163A1 (en) * | 2001-11-26 | 2004-02-19 | Lab Vision Corporation | Automated tissue staining system and reagent container |
| US7368080B2 (en) * | 2002-01-18 | 2008-05-06 | Sysmex Corporation | Smear preparing apparatus |
| US8449822B2 (en) * | 2002-01-18 | 2013-05-28 | Sysmex Corporation | Smear preparing apparatuses and methods of preparing sample smears |
| GB2385156B (en) * | 2002-02-06 | 2005-08-10 | Inventec Corp | Automatic storage and retrieval system and method |
| US7468161B2 (en) * | 2002-04-15 | 2008-12-23 | Ventana Medical Systems, Inc. | Automated high volume slide processing system |
| CN1650159A (zh) | 2002-04-26 | 2005-08-03 | 万堂医药系统公司 | 具有固定载玻片平台的自动化分子病理学装置 |
| WO2004003570A1 (en) * | 2002-06-28 | 2004-01-08 | Preyas Sarabhai Shah | Slide stainer with controlled fluid flow |
| US7125722B2 (en) * | 2002-07-03 | 2006-10-24 | Abbott Laboratories | Apparatus and method for handling fluids for analysis |
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Also Published As
| Publication number | Publication date |
|---|---|
| EP1004013A1 (en) | 2000-05-31 |
| EP1004013B1 (en) | 2015-04-15 |
| JP2009002952A (ja) | 2009-01-08 |
| CA2301286C (en) | 2005-06-14 |
| JP4354000B2 (ja) | 2009-10-28 |
| AU8826198A (en) | 1999-03-01 |
| US20020034456A1 (en) | 2002-03-21 |
| US6945128B2 (en) | 2005-09-20 |
| US6416713B1 (en) | 2002-07-09 |
| US6045759A (en) | 2000-04-04 |
| CA2301286A1 (en) | 1999-02-18 |
| WO1999008090A1 (en) | 1999-02-18 |
| EP1004013A4 (en) | 2006-02-01 |
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