JP2001511781A5 - - Google Patents
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- Publication number
- JP2001511781A5 JP2001511781A5 JP1998533144A JP53314498A JP2001511781A5 JP 2001511781 A5 JP2001511781 A5 JP 2001511781A5 JP 1998533144 A JP1998533144 A JP 1998533144A JP 53314498 A JP53314498 A JP 53314498A JP 2001511781 A5 JP2001511781 A5 JP 2001511781A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Description
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9702194.3A GB9702194D0 (en) | 1997-02-04 | 1997-02-04 | Sulphonide derivatives |
| GB9702194.3 | 1997-02-04 | ||
| PCT/US1998/001881 WO1998033496A1 (en) | 1997-02-04 | 1998-01-30 | Sulphonamide derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001511781A JP2001511781A (ja) | 2001-08-14 |
| JP2001511781A5 true JP2001511781A5 (ja) | 2005-10-06 |
Family
ID=10807015
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP53314498A Ceased JP2001511781A (ja) | 1997-02-04 | 1998-01-30 | スルホンアミド誘導体 |
Country Status (29)
| Country | Link |
|---|---|
| US (3) | US6303816B1 (ja) |
| EP (2) | EP1528055A2 (ja) |
| JP (1) | JP2001511781A (ja) |
| KR (1) | KR20000070753A (ja) |
| CN (1) | CN1251523A (ja) |
| AR (1) | AR011623A1 (ja) |
| AT (1) | ATE284385T1 (ja) |
| AU (1) | AU760056B2 (ja) |
| BR (1) | BR9807297A (ja) |
| CA (1) | CA2278790A1 (ja) |
| CO (1) | CO5080767A1 (ja) |
| DE (1) | DE69827984T2 (ja) |
| DK (1) | DK0860428T3 (ja) |
| EA (1) | EA001919B1 (ja) |
| ES (1) | ES2232914T3 (ja) |
| GB (1) | GB9702194D0 (ja) |
| HU (1) | HUP0002208A3 (ja) |
| ID (1) | ID22500A (ja) |
| IL (1) | IL130970A (ja) |
| NO (1) | NO993667L (ja) |
| NZ (1) | NZ336559A (ja) |
| PE (1) | PE72899A1 (ja) |
| PL (1) | PL334963A1 (ja) |
| PT (1) | PT860428E (ja) |
| SI (1) | SI0860428T1 (ja) |
| TR (1) | TR199902368T2 (ja) |
| UA (1) | UA71892C2 (ja) |
| WO (1) | WO1998033496A1 (ja) |
| ZA (1) | ZA98842B (ja) |
Families Citing this family (98)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6613804B2 (en) | 1993-05-20 | 2003-09-02 | Encysive Pharmaceuticals, Inc. | Biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin |
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| US6432994B1 (en) | 1997-04-28 | 2002-08-13 | Texas Biotechnology Corporation | Sulfonamides for treatment of endothelin-mediated disorders |
| FR2763331B1 (fr) * | 1997-05-16 | 1999-06-25 | Rhodia Chimie Sa | Procede de synthese de sulfonimides et de leurs sels |
| WO1999043285A2 (en) | 1998-02-24 | 1999-09-02 | Eli Lilly And Company | Sulphonamide derivatives |
| CA2338994A1 (en) | 1998-07-31 | 2000-02-10 | Paul Leslie Ornstein | Sulfonamide derivatives |
| US6617351B1 (en) | 1998-07-31 | 2003-09-09 | Eli Lilly And Company | Amide, carbamate, and urea derivatives |
| PE20000943A1 (es) * | 1998-07-31 | 2000-09-28 | Lilly Co Eli | Derivados de sulfonamida |
| US6358981B1 (en) | 1998-07-31 | 2002-03-19 | Eli Lilly And Company | Sulphonamide derivatives |
| WO2000006539A1 (en) | 1998-07-31 | 2000-02-10 | Eli Lilly And Company | Alkenyl sulphonamide derivatives |
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| PE20000944A1 (es) * | 1998-07-31 | 2000-09-20 | Lilly Co Eli | Derivados de sulfonamida |
| CA2339099A1 (en) | 1998-07-31 | 2000-02-10 | Macklin Brian Arnold | Sulfonamide derivatives |
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| US6521605B1 (en) | 1998-07-31 | 2003-02-18 | Eli Lilly And Company | Amidophosphate derivatives |
| US6693137B1 (en) | 1998-07-31 | 2004-02-17 | Eli Lilly And Company | Sulphonamide derivatives |
| US6503935B1 (en) | 1998-08-07 | 2003-01-07 | Abbott Laboratories | Imidazoles and related compounds as α1A agonists |
| CA2372490A1 (en) * | 1999-04-30 | 2000-11-09 | Eli Lilly And Company | Monofluoroalkyl derivatives |
| US6639107B1 (en) | 1999-12-08 | 2003-10-28 | Eli Lilly And Company | Cyclopentyl sulfonamide derivatives |
| US6800651B2 (en) * | 2000-02-03 | 2004-10-05 | Eli Lilly And Company | Potentiators of glutamate receptors |
| AU2001241512A1 (en) | 2000-03-13 | 2001-09-24 | Eli Lilly And Company | Sulfonamide derivatives |
| CA2409829A1 (en) | 2000-05-19 | 2001-11-29 | Eli Lilly And Company | Sulfonamide derivatives |
| US6984756B2 (en) * | 2000-05-19 | 2006-01-10 | Eli Lilly And Company | Process for preparing biphenyl compounds |
| WO2001089510A2 (en) * | 2000-05-24 | 2001-11-29 | Eli Lilly And Company | Use of an ampa receptor potentiator for the treatment of obesity |
| WO2001094306A2 (en) * | 2000-06-06 | 2001-12-13 | Eli Lilly And Company | (bis)sulfonamide derivatives |
| DE60104697T2 (de) * | 2000-06-13 | 2005-08-04 | Eli Lilly And Co., Indianapolis | Sulfonamid-derivate |
| AU2001284649A1 (en) * | 2000-08-31 | 2002-03-13 | Eli Lilly And Company | Acetylenic sulfonamide derivatives |
| WO2002022579A2 (en) | 2000-09-11 | 2002-03-21 | Sepracor, Inc. | Antipsychotic sulfonamide-heterocycles, and methods of use thereof |
| JP2004511540A (ja) * | 2000-10-13 | 2004-04-15 | イーライ・リリー・アンド・カンパニー | シクロアルキルフルオロスルホンアミド誘導体 |
| CA2446161A1 (en) * | 2001-05-04 | 2002-11-14 | Emanuele Sher | Use of an ampa receptor potentiator for the manufacture of a medicament for the treatment of type 2 diabetes |
| JP2002338538A (ja) * | 2001-05-21 | 2002-11-27 | Takeda Schering-Plough Animal Health Kk | 新規スルホンアミド誘導体およびそれを含む魚類用抗寄生虫薬 |
| US20040157817A1 (en) * | 2001-05-30 | 2004-08-12 | Cantell Buddy Eugene | Cycloalkenylsulfonamide derivatives |
| CA2446716A1 (en) * | 2001-06-05 | 2002-12-12 | Eli Lilly And Company | Sulfonamide derivatives |
| US20040235957A1 (en) * | 2001-10-12 | 2004-11-25 | David Bleakman | Use of sulfonamide derivatives as pharmaceuticals compounds |
| US7312214B2 (en) | 2002-05-10 | 2007-12-25 | Bristol-Myers Squibb Company | 1, 1-disubstituted cycloalkyl derivatives as factor Xa inhibitors |
| US7307191B2 (en) * | 2003-01-06 | 2007-12-11 | Oh Technologies Llp | Organic peroxyacid precursors |
| US7615187B2 (en) * | 2003-01-06 | 2009-11-10 | D H Technologies, LLP | Organic peroxyacid precursors |
| US7005549B2 (en) * | 2003-01-06 | 2006-02-28 | Hobson David W | Peracid precursors for antimicrobial use |
| CA2527170A1 (en) * | 2003-04-15 | 2004-10-28 | Astrazeneca Ab | Therapeutic compounds |
| WO2005013961A1 (en) * | 2003-07-17 | 2005-02-17 | Eli Lilly And Company | Combination therapy for treatment of cognitive disorders or psychoses |
| US7625932B2 (en) | 2003-10-08 | 2009-12-01 | Eli Lilly And Company | Pyrrole and pyrazole derivatives as potentiators of glutamate receptors |
| ATE517867T1 (de) * | 2005-02-15 | 2011-08-15 | Glaxo Group Ltd | Verbindungen, die den glutamatrezeptor verstärken und anwendungen davon in der medizin |
| DE602006003661D1 (de) | 2005-06-06 | 2008-12-24 | Lilly Co Eli | Ampa-rezeptoren-verstärker |
| US7910179B2 (en) * | 2005-11-23 | 2011-03-22 | Lg Chem, Ltd. | Vinylsulfone derivative, liquid crystal composition comprising the same and compensation film using the same liquid crystal composition |
| US20070293573A1 (en) * | 2006-02-24 | 2007-12-20 | Eric Gouaux | Glu2 receptor modulators |
| US8097652B2 (en) * | 2006-12-11 | 2012-01-17 | Eli Lilly And Company | AMPA receptor potentiators |
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| AR072297A1 (es) | 2008-06-27 | 2010-08-18 | Novartis Ag | Derivados de indol-2-il-piridin-3-ilo, composicion farmaceutica que los comprende y su uso en medicamentos para el tratamiento de enfermedades mediadas por la sintasa aldosterona. |
| US20110218190A1 (en) * | 2008-11-10 | 2011-09-08 | The Regents Of The University Of California | Therapeutic uses of ampa receptor modulators for treatment of motor dysfunction |
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| US20130253022A1 (en) * | 2010-11-30 | 2013-09-26 | Fox Chase Chemical Diversity Center, Inc. | Novel fluorinated sulfamides exhibiting neuroprotective action and their method of use |
| US9375009B2 (en) * | 2011-12-27 | 2016-06-28 | Bayer Intellectual Property Gmbh | Heteroarylpiperidine and piperazine derivatives as fungicides |
| US9073856B2 (en) | 2012-01-23 | 2015-07-07 | Eli Lilly And Company | Phenyl methanesulfonamide derivatives useful as MGAT-2 inhibitors |
| AP2014007793A0 (en) | 2012-01-31 | 2014-07-31 | Lilly Co Eli | Novel morpholinyl derivatives useful as mogat-2 inhibitors |
| WO2013130501A1 (en) * | 2012-03-01 | 2013-09-06 | The Board Of Regents Of The University Of Texas System | Bivalent ampa receptor positive allosteric modulators |
| EP2836482B1 (en) | 2012-04-10 | 2019-12-25 | The Regents of The University of California | Compositions and methods for treating cancer |
| MX2015005739A (es) | 2012-11-06 | 2015-09-16 | Lilly Co Eli | Compuestos novedosos de bencil sulfonamida utiles como inhibidores de mogat-2. |
| US9745319B2 (en) | 2013-03-15 | 2017-08-29 | Araxes Pharma Llc | Irreversible covalent inhibitors of the GTPase K-Ras G12C |
| US9227978B2 (en) | 2013-03-15 | 2016-01-05 | Araxes Pharma Llc | Covalent inhibitors of Kras G12C |
| CN103145637A (zh) * | 2013-03-17 | 2013-06-12 | 石家庄学院 | 3-苯基-5-溴-1,2,4-噁二唑衍生物的合成新工艺 |
| EP3311842A1 (en) | 2013-06-13 | 2018-04-25 | VeroScience LLC | Compositions and methods for treating metabolic disorders |
| JO3805B1 (ar) | 2013-10-10 | 2021-01-31 | Araxes Pharma Llc | مثبطات كراس جي12سي |
| JO3556B1 (ar) | 2014-09-18 | 2020-07-05 | Araxes Pharma Llc | علاجات مدمجة لمعالجة السرطان |
| US10011600B2 (en) | 2014-09-25 | 2018-07-03 | Araxes Pharma Llc | Methods and compositions for inhibition of Ras |
| JP2017528498A (ja) | 2014-09-25 | 2017-09-28 | アラクセス ファーマ エルエルシー | Ｋｒａｓ ｇ１２ｃ変異体タンパク質のインヒビター |
| CN104496920A (zh) * | 2014-12-04 | 2015-04-08 | 北京理工大学 | 一种n-烯丙基-二取代四唑及其制备方法和检测方法 |
| CN107849022A (zh) | 2015-04-10 | 2018-03-27 | 亚瑞克西斯制药公司 | 取代的喹唑啉化合物和其使用方法 |
| EP3283462B1 (en) | 2015-04-15 | 2020-12-02 | Araxes Pharma LLC | Fused-tricyclic inhibitors of kras and methods of use thereof |
| US10144724B2 (en) | 2015-07-22 | 2018-12-04 | Araxes Pharma Llc | Substituted quinazoline compounds and methods of use thereof |
| US10689356B2 (en) | 2015-09-28 | 2020-06-23 | Araxes Pharma Llc | Inhibitors of KRAS G12C mutant proteins |
| EP3356354A1 (en) | 2015-09-28 | 2018-08-08 | Araxes Pharma LLC | Inhibitors of kras g12c mutant proteins |
| US10975071B2 (en) | 2015-09-28 | 2021-04-13 | Araxes Pharma Llc | Inhibitors of KRAS G12C mutant proteins |
| WO2017058792A1 (en) | 2015-09-28 | 2017-04-06 | Araxes Pharma Llc | Inhibitors of kras g12c mutant proteins |
| EP3356351A1 (en) | 2015-09-28 | 2018-08-08 | Araxes Pharma LLC | Inhibitors of kras g12c mutant proteins |
| EP3356347A1 (en) | 2015-09-28 | 2018-08-08 | Araxes Pharma LLC | Inhibitors of kras g12c mutant proteins |
| WO2017058728A1 (en) | 2015-09-28 | 2017-04-06 | Araxes Pharma Llc | Inhibitors of kras g12c mutant proteins |
| WO2017070256A2 (en) | 2015-10-19 | 2017-04-27 | Araxes Pharma Llc | Method for screening inhibitors of ras |
| US10414757B2 (en) | 2015-11-16 | 2019-09-17 | Araxes Pharma Llc | 2-substituted quinazoline compounds comprising a substituted heterocyclic group and methods of use thereof |
| US9988357B2 (en) | 2015-12-09 | 2018-06-05 | Araxes Pharma Llc | Methods for preparation of quinazoline derivatives |
| WO2017172979A1 (en) | 2016-03-30 | 2017-10-05 | Araxes Pharma Llc | Substituted quinazoline compounds and methods of use |
| US10646488B2 (en) | 2016-07-13 | 2020-05-12 | Araxes Pharma Llc | Conjugates of cereblon binding compounds and G12C mutant KRAS, HRAS or NRAS protein modulating compounds and methods of use thereof |
| CN110036010A (zh) | 2016-09-29 | 2019-07-19 | 亚瑞克西斯制药公司 | Kras g12c突变蛋白的抑制剂 |
| CN110312711A (zh) | 2016-10-07 | 2019-10-08 | 亚瑞克西斯制药公司 | 作为ras抑制剂的杂环化合物及其使用方法 |
| US11358959B2 (en) | 2017-01-26 | 2022-06-14 | Araxes Pharma Llc | Benzothiophene and benzothiazole compounds and methods of use thereof |
| US11279689B2 (en) | 2017-01-26 | 2022-03-22 | Araxes Pharma Llc | 1-(3-(6-(3-hydroxynaphthalen-1-yl)benzofuran-2-yl)azetidin-1 yl)prop-2-en-1-one derivatives and similar compounds as KRAS G12C modulators for treating cancer |
| WO2018140512A1 (en) | 2017-01-26 | 2018-08-02 | Araxes Pharma Llc | Fused bicyclic benzoheteroaromatic compounds and methods of use thereof |
| EP3573970A1 (en) | 2017-01-26 | 2019-12-04 | Araxes Pharma LLC | 1-(6-(3-hydroxynaphthalen-1-yl)quinazolin-2-yl)azetidin-1-yl)prop-2-en-1-one derivatives and similar compounds as kras g12c inhibitors for the treatment of cancer |
| CN110382482A (zh) | 2017-01-26 | 2019-10-25 | 亚瑞克西斯制药公司 | 稠合的杂-杂二环化合物及其使用方法 |
| EP3630747A1 (en) | 2017-05-25 | 2020-04-08 | Araxes Pharma LLC | Quinazoline derivatives as modulators of mutant kras, hras or nras |
| TW201906832A (zh) | 2017-05-25 | 2019-02-16 | 美商亞瑞克西斯製藥公司 | 用於癌症治療之化合物及其使用方法 |
| CN110869358A (zh) | 2017-05-25 | 2020-03-06 | 亚瑞克西斯制药公司 | Kras的共价抑制剂 |
| CN110577512B (zh) * | 2019-09-20 | 2021-01-26 | 河南大学 | 非对称结构5-烷氧基-2,3′-联噻吩及溴代衍生物的制备方法 |
| US11919833B2 (en) * | 2021-04-26 | 2024-03-05 | Mitsubishi Gas Chemical Company, Inc. | Compound and method for producing same |
| CN114436911B (zh) * | 2022-03-17 | 2023-04-28 | 南京林业大学 | 一种樟脑磺酰苄胺类化合物的制备方法及其应用 |
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| PE20000942A1 (es) | 1998-07-31 | 2000-09-28 | Lilly Co Eli | Derivados de amida, carbamato y urea |
| CA2339099A1 (en) | 1998-07-31 | 2000-02-10 | Macklin Brian Arnold | Sulfonamide derivatives |
| US6358982B1 (en) | 1998-07-31 | 2002-03-19 | Eli Lilly And Company | Heterocyclyl sulphonamide derivatives |
| US6358981B1 (en) | 1998-07-31 | 2002-03-19 | Eli Lilly And Company | Sulphonamide derivatives |
| PE20000943A1 (es) | 1998-07-31 | 2000-09-28 | Lilly Co Eli | Derivados de sulfonamida |
| WO2000006539A1 (en) | 1998-07-31 | 2000-02-10 | Eli Lilly And Company | Alkenyl sulphonamide derivatives |
| AU5240099A (en) | 1998-07-31 | 2000-02-21 | Eli Lilly And Company | Heterocyclic sulphonamide derivatives |
| AU5235599A (en) | 1998-07-31 | 2000-02-21 | Eli Lilly And Company | N-substituted sulfonamide derivatives |
| CA2338994A1 (en) | 1998-07-31 | 2000-02-10 | Paul Leslie Ornstein | Sulfonamide derivatives |
| PE20000944A1 (es) | 1998-07-31 | 2000-09-20 | Lilly Co Eli | Derivados de sulfonamida |
| US6521605B1 (en) | 1998-07-31 | 2003-02-18 | Eli Lilly And Company | Amidophosphate derivatives |
| CA2372490A1 (en) | 1999-04-30 | 2000-11-09 | Eli Lilly And Company | Monofluoroalkyl derivatives |
| WO2001042203A1 (en) | 1999-12-08 | 2001-06-14 | Eli Lilly And Company | Cyclopentyl sulfonamide derivatives |
| AU2001241512A1 (en) | 2000-03-13 | 2001-09-24 | Eli Lilly And Company | Sulfonamide derivatives |
| PL362893A1 (en) | 2000-05-19 | 2004-11-02 | Eli Lilly And Company | A process for preparing biphenyl compounds |
| CA2409829A1 (en) | 2000-05-19 | 2001-11-29 | Eli Lilly And Company | Sulfonamide derivatives |
| MXPA02010020A (es) | 2000-05-19 | 2003-02-12 | Lilly Co Eli | Derivados de sulfonamida. |
| DE60104697T2 (de) | 2000-06-13 | 2005-08-04 | Eli Lilly And Co., Indianapolis | Sulfonamid-derivate |
| WO2002014294A2 (en) | 2000-08-11 | 2002-02-21 | Eli Lilly And Company | Heterocyclic sulfonamide derivatives and their use for potentiating glutamate receptor function |
| WO2002014275A2 (en) | 2000-08-11 | 2002-02-21 | Eli Lilly And Company | Heterocyclic sulfonamide derivatives and their use for potentiating glutamate receptor function |
| AU2001284649A1 (en) | 2000-08-31 | 2002-03-13 | Eli Lilly And Company | Acetylenic sulfonamide derivatives |
| JP2004511540A (ja) | 2000-10-13 | 2004-04-15 | イーライ・リリー・アンド・カンパニー | シクロアルキルフルオロスルホンアミド誘導体 |
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| US20040157817A1 (en) | 2001-05-30 | 2004-08-12 | Cantell Buddy Eugene | Cycloalkenylsulfonamide derivatives |
| CA2446716A1 (en) | 2001-06-05 | 2002-12-12 | Eli Lilly And Company | Sulfonamide derivatives |
-
1997
- 1997-02-04 GB GBGB9702194.3A patent/GB9702194D0/en active Pending
- 1997-06-17 US US09/355,605 patent/US6303816B1/en not_active Expired - Lifetime
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1998
- 1998-01-30 JP JP53314498A patent/JP2001511781A/ja not_active Ceased
- 1998-01-30 HU HU0002208A patent/HUP0002208A3/hu unknown
- 1998-01-30 TR TR1999/02368T patent/TR199902368T2/xx unknown
- 1998-01-30 CN CN98803753A patent/CN1251523A/zh active Pending
- 1998-01-30 NZ NZ336559A patent/NZ336559A/xx unknown
- 1998-01-30 CA CA002278790A patent/CA2278790A1/en not_active Abandoned
- 1998-01-30 EA EA199900719A patent/EA001919B1/ru not_active IP Right Cessation
- 1998-01-30 KR KR1019997007012A patent/KR20000070753A/ko not_active Application Discontinuation
- 1998-01-30 WO PCT/US1998/001881 patent/WO1998033496A1/en not_active Application Discontinuation
- 1998-01-30 UA UA99084464A patent/UA71892C2/uk unknown
- 1998-01-30 AU AU62595/98A patent/AU760056B2/en not_active Ceased
- 1998-01-30 BR BR9807297-8A patent/BR9807297A/pt not_active Application Discontinuation
- 1998-01-30 ID IDW990754A patent/ID22500A/id unknown
- 1998-01-30 IL IL13097098A patent/IL130970A/xx not_active IP Right Cessation
- 1998-01-30 PL PL98334963A patent/PL334963A1/xx not_active Application Discontinuation
- 1998-02-02 CO CO98004892A patent/CO5080767A1/es unknown
- 1998-02-02 ZA ZA9800842A patent/ZA98842B/xx unknown
- 1998-02-03 ES ES98300759T patent/ES2232914T3/es not_active Expired - Lifetime
- 1998-02-03 SI SI9830743T patent/SI0860428T1/xx unknown
- 1998-02-03 DK DK98300759T patent/DK0860428T3/da active
- 1998-02-03 EP EP04104929A patent/EP1528055A2/en not_active Withdrawn
- 1998-02-03 DE DE69827984T patent/DE69827984T2/de not_active Expired - Lifetime
- 1998-02-03 EP EP98300759A patent/EP0860428B1/en not_active Expired - Lifetime
- 1998-02-03 AT AT98300759T patent/ATE284385T1/de not_active IP Right Cessation
- 1998-02-03 PT PT98300759T patent/PT860428E/pt unknown
- 1998-02-04 AR ARP980100477A patent/AR011623A1/es unknown
- 1998-02-04 PE PE1998000078A patent/PE72899A1/es not_active Application Discontinuation
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1999
- 1999-07-28 NO NO993667A patent/NO993667L/no not_active Application Discontinuation
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2001
- 2001-07-25 US US09/912,809 patent/US6596716B2/en not_active Expired - Fee Related
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2003
- 2003-05-29 US US10/447,619 patent/US7135487B2/en not_active Expired - Fee Related