JP2001510028A5 - - Google Patents
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- Publication number
- JP2001510028A5 JP2001510028A5 JP2000502802A JP2000502802A JP2001510028A5 JP 2001510028 A5 JP2001510028 A5 JP 2001510028A5 JP 2000502802 A JP2000502802 A JP 2000502802A JP 2000502802 A JP2000502802 A JP 2000502802A JP 2001510028 A5 JP2001510028 A5 JP 2001510028A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- vector
- expression vector
- polypeptide
- vascular proliferative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 description 17
- 239000013604 expression vector Substances 0.000 description 6
- 229920001184 polypeptide Polymers 0.000 description 5
- 102000004196 processed proteins & peptides Human genes 0.000 description 5
- 108090000765 processed proteins & peptides Proteins 0.000 description 5
- 108090000623 proteins and genes Proteins 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 102000037865 fusion proteins Human genes 0.000 description 4
- 108020001507 fusion proteins Proteins 0.000 description 4
- 230000002062 proliferating effect Effects 0.000 description 4
- 230000002792 vascular Effects 0.000 description 4
- 239000013598 vector Substances 0.000 description 4
- 201000010099 disease Diseases 0.000 description 3
- 102000006601 Thymidine Kinase Human genes 0.000 description 2
- 108020004440 Thymidine kinase Proteins 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 241000701161 unidentified adenovirus Species 0.000 description 2
- 201000001320 Atherosclerosis Diseases 0.000 description 1
- 108020004414 DNA Proteins 0.000 description 1
- 241000206602 Eukaryota Species 0.000 description 1
- 108091028043 Nucleic acid sequence Proteins 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 125000003275 alpha amino acid group Chemical group 0.000 description 1
- 230000033115 angiogenesis Effects 0.000 description 1
- 230000004663 cell proliferation Effects 0.000 description 1
- 239000002299 complementary DNA Substances 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 239000002502 liposome Substances 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 208000037803 restenosis Diseases 0.000 description 1
- 210000000329 smooth muscle myocyte Anatomy 0.000 description 1
- 239000013603 viral vector Substances 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/897,333 | 1997-07-21 | ||
| US08/897,333 US6177272B1 (en) | 1997-07-21 | 1997-07-21 | Method for treating vascular proliferative diseases with p27 and fusions thereof |
| PCT/US1998/015025 WO1999003508A2 (en) | 1997-07-21 | 1998-07-21 | METHOD FOR TREATING VASCULAR PROLIFERATIVE DISEASES WITH p27 AND FUSIONS THEREOF |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001510028A JP2001510028A (ja) | 2001-07-31 |
| JP2001510028A5 true JP2001510028A5 (enExample) | 2006-01-05 |
Family
ID=25407780
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000502802A Pending JP2001510028A (ja) | 1997-07-21 | 1998-07-21 | ｐ２７およびその融合物で血管増殖性疾患を処置する方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6177272B1 (enExample) |
| EP (1) | EP0998307B1 (enExample) |
| JP (1) | JP2001510028A (enExample) |
| AT (1) | ATE342067T1 (enExample) |
| AU (1) | AU8502198A (enExample) |
| CA (1) | CA2295199C (enExample) |
| DE (1) | DE69836139T2 (enExample) |
| WO (1) | WO1999003508A2 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6273913B1 (en) | 1997-04-18 | 2001-08-14 | Cordis Corporation | Modified stent useful for delivery of drugs along stent strut |
| CA2362995A1 (en) | 1999-03-01 | 2000-09-08 | Cell Genesys, Inc. | Anti-neoplastic compositions and uses thereof |
| US6413943B1 (en) * | 1999-03-01 | 2002-07-02 | Cell Genesys, Inc. | Methods and reagents for inhibiting proliferation of smooth muscle cells |
| US6420345B1 (en) * | 1999-03-01 | 2002-07-16 | Cell Genesys, Inc. | Methods and reagents for inhibiting angiogenesis |
| JP4684512B2 (ja) * | 1999-09-22 | 2011-05-18 | 信之 宮坂 | ｐ２１Ｃｉｐ１リウマチ治療剤 |
| US8236048B2 (en) * | 2000-05-12 | 2012-08-07 | Cordis Corporation | Drug/drug delivery systems for the prevention and treatment of vascular disease |
| US6776796B2 (en) | 2000-05-12 | 2004-08-17 | Cordis Corportation | Antiinflammatory drug and delivery device |
| US20040243097A1 (en) * | 2000-05-12 | 2004-12-02 | Robert Falotico | Antiproliferative drug and delivery device |
| US20050002986A1 (en) * | 2000-05-12 | 2005-01-06 | Robert Falotico | Drug/drug delivery systems for the prevention and treatment of vascular disease |
| US7300662B2 (en) | 2000-05-12 | 2007-11-27 | Cordis Corporation | Drug/drug delivery systems for the prevention and treatment of vascular disease |
| DE60124285T3 (de) * | 2000-09-29 | 2011-03-17 | Cordis Corp., Miami Lakes | Beschichtete medizinische geräte |
| US20020111590A1 (en) * | 2000-09-29 | 2002-08-15 | Davila Luis A. | Medical devices, drug coatings and methods for maintaining the drug coatings thereon |
| US20020051730A1 (en) * | 2000-09-29 | 2002-05-02 | Stanko Bodnar | Coated medical devices and sterilization thereof |
| US7261735B2 (en) * | 2001-05-07 | 2007-08-28 | Cordis Corporation | Local drug delivery devices and methods for maintaining the drug coatings thereon |
| US20020098998A1 (en) * | 2001-01-22 | 2002-07-25 | Marks Andrew R. | P27 prevents cellular migration |
| US20030013638A1 (en) * | 2001-01-22 | 2003-01-16 | Marks Andrew R. | P27 prevents cellular migration |
| US7195640B2 (en) * | 2001-09-25 | 2007-03-27 | Cordis Corporation | Coated medical devices for the treatment of vulnerable plaque |
| US20030065377A1 (en) * | 2001-09-28 | 2003-04-03 | Davila Luis A. | Coated medical devices |
| US20030065345A1 (en) * | 2001-09-28 | 2003-04-03 | Kevin Weadock | Anastomosis devices and methods for treating anastomotic sites |
| US7108701B2 (en) * | 2001-09-28 | 2006-09-19 | Ethicon, Inc. | Drug releasing anastomosis devices and methods for treating anastomotic sites |
| US20050069918A1 (en) * | 2003-05-29 | 2005-03-31 | Francois Claret | JAB1 as a prognostic marker and a therapeutic target for human cancer |
| US7833339B2 (en) | 2006-04-18 | 2010-11-16 | Franklin Industrial Minerals | Mineral filler composition |
| CA2715765A1 (en) * | 2008-02-19 | 2009-08-27 | Celladon Corporation | Compositions for enhanced uptake of viral vectors in the myocardium |
| KR20220051164A (ko) | 2019-07-05 | 2022-04-26 | 아이오엠엑스 테라퓨틱스 아게 | Igsf11 (vsig3)의 항체 결합 igc2 및 이의 용도 |
| EP4175668A1 (en) | 2020-07-06 | 2023-05-10 | iOmx Therapeutics AG | Antibodies binding igv of igsf11 (vsig3) and uses thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5328470A (en) * | 1989-03-31 | 1994-07-12 | The Regents Of The University Of Michigan | Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor |
| US6355774B1 (en) | 1994-01-07 | 2002-03-12 | Fred Hutchinson Cancer Research Center | Isolated p27 protein |
| WO1996002140A1 (en) | 1994-07-15 | 1996-02-01 | Sloan-Kettering Institute For Cancer Research | ISOLATED p27 PROTEIN AND METHODS FOR ITS PRODUCTION AND USE |
| US6316208B1 (en) | 1994-01-07 | 2001-11-13 | Memorial Sloan-Kettering Cancer Center | Methods for determining isolated p27 protein levels and uses thereof |
| US6242575B1 (en) | 1994-01-07 | 2001-06-05 | Fred Hutchinson Institute For Cancer Research | Antibodies for detecting p27 protein |
| US5688665A (en) | 1994-01-07 | 1997-11-18 | Fred Hutchinson Cancer Research Center | Isolated nucleic acid molecules encoding the p27 KIP-1 protein |
| WO1996025507A2 (en) * | 1995-02-17 | 1996-08-22 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Methods of preparation and use of recombinant adenoviral vectors |
| US5962424A (en) * | 1995-02-21 | 1999-10-05 | Arch Development Corporation | Methods and compositions for targeting selectins |
| US5863904A (en) * | 1995-09-26 | 1999-01-26 | The University Of Michigan | Methods for treating cancers and restenosis with P21 |
| US6541197B2 (en) * | 1996-01-22 | 2003-04-01 | Human Gene Therapy Research Institute | Vehicles for stable transfer of green fluorescent protein gene and methods of use for same |
| US5672508A (en) * | 1996-01-23 | 1997-09-30 | Mitotix, Inc. | Inhibitors of cell-cycle progression, and uses related thereto |
| AU5253998A (en) * | 1996-11-13 | 1998-06-03 | Board Of Regents, The University Of Texas System | Diminishing viral gene expression by promoter replacement |
-
1997
- 1997-07-21 US US08/897,333 patent/US6177272B1/en not_active Expired - Fee Related
-
1998
- 1998-07-21 AT AT98935852T patent/ATE342067T1/de not_active IP Right Cessation
- 1998-07-21 CA CA002295199A patent/CA2295199C/en not_active Expired - Fee Related
- 1998-07-21 JP JP2000502802A patent/JP2001510028A/ja active Pending
- 1998-07-21 DE DE69836139T patent/DE69836139T2/de not_active Expired - Fee Related
- 1998-07-21 AU AU85021/98A patent/AU8502198A/en not_active Abandoned
- 1998-07-21 EP EP98935852A patent/EP0998307B1/en not_active Expired - Lifetime
- 1998-07-21 WO PCT/US1998/015025 patent/WO1999003508A2/en not_active Ceased
-
2000
- 2000-11-07 US US09/708,276 patent/US6884431B1/en not_active Expired - Fee Related
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