JP2004518410A5 - - Google Patents
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- Publication number
- JP2004518410A5 JP2004518410A5 JP2002524039A JP2002524039A JP2004518410A5 JP 2004518410 A5 JP2004518410 A5 JP 2004518410A5 JP 2002524039 A JP2002524039 A JP 2002524039A JP 2002524039 A JP2002524039 A JP 2002524039A JP 2004518410 A5 JP2004518410 A5 JP 2004518410A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- bard1
- nucleic acid
- sequence
- host cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001184 polypeptide Polymers 0.000 description 24
- 102000004196 processed proteins & peptides Human genes 0.000 description 24
- 108090000765 processed proteins & peptides Proteins 0.000 description 24
- 238000000034 method Methods 0.000 description 9
- 150000001413 amino acids Chemical class 0.000 description 7
- 150000007523 nucleic acids Chemical class 0.000 description 7
- 210000004027 cell Anatomy 0.000 description 6
- 239000008194 pharmaceutical composition Substances 0.000 description 6
- 239000012472 biological sample Substances 0.000 description 5
- 108020004707 nucleic acids Proteins 0.000 description 5
- 102000039446 nucleic acids Human genes 0.000 description 5
- 239000013604 expression vector Substances 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 102000004169 proteins and genes Human genes 0.000 description 4
- 238000000338 in vitro Methods 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 101700002522 BARD1 Proteins 0.000 description 2
- 102100028048 BRCA1-associated RING domain protein 1 Human genes 0.000 description 2
- 101000697486 Homo sapiens BRCA1-associated RING domain protein 1 Proteins 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- 108091028043 Nucleic acid sequence Proteins 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 210000004899 c-terminal region Anatomy 0.000 description 2
- 238000010367 cloning Methods 0.000 description 2
- 239000013599 cloning vector Substances 0.000 description 2
- 238000012258 culturing Methods 0.000 description 2
- 102000049586 human BARD1 Human genes 0.000 description 2
- 239000002773 nucleotide Substances 0.000 description 2
- 125000003729 nucleotide group Chemical group 0.000 description 2
- 239000000825 pharmaceutical preparation Substances 0.000 description 2
- 229940127557 pharmaceutical product Drugs 0.000 description 2
- 239000013598 vector Substances 0.000 description 2
- 101100004192 Rattus norvegicus Bard1 gene Proteins 0.000 description 1
- 238000011394 anticancer treatment Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 230000000861 pro-apoptotic effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0011207A FR2813606B1 (fr) | 2000-09-01 | 2000-09-01 | Proteine bard1 tronquee, et ses applications diagnostiques et therapeutiques |
| FR00/11207 | 2000-09-01 | ||
| PCT/FR2001/002731 WO2002018536A2 (fr) | 2000-09-01 | 2001-09-03 | Proteine bard1 tronquee, et ses applications diagnostiques et therapeutiques |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004518410A JP2004518410A (ja) | 2004-06-24 |
| JP2004518410A5 true JP2004518410A5 (enExample) | 2011-12-08 |
| JP4995399B2 JP4995399B2 (ja) | 2012-08-08 |
Family
ID=8853916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002524039A Expired - Fee Related JP4995399B2 (ja) | 2000-09-01 | 2001-09-03 | 切断されたｂａｒｄ１タンパク質、並びにその診断上及び治療上の利用 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7566764B2 (enExample) |
| EP (1) | EP1313855B1 (enExample) |
| JP (1) | JP4995399B2 (enExample) |
| AT (1) | ATE328082T1 (enExample) |
| CA (1) | CA2421258C (enExample) |
| DE (1) | DE60120187T2 (enExample) |
| FR (1) | FR2813606B1 (enExample) |
| WO (1) | WO2002018536A2 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100130590A1 (en) * | 2007-04-02 | 2010-05-27 | Hopitaux Universitaires De Geneve | Deletion bearing bard1 isoforms and use thereof |
| CN103238069B (zh) * | 2010-08-17 | 2016-06-29 | 日内瓦大学 | 肺癌和结直肠癌中的bard1同工型及其应用 |
| EP3063543B1 (en) | 2013-10-31 | 2020-03-11 | Regeneron Pharmaceuticals, Inc. | Competitive ligand binding assay for detecting neutralizing antibodies |
| EP2871480A1 (en) | 2013-11-06 | 2015-05-13 | Bard1Ag SA | Lung Cancer Diagnosis |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998012327A2 (en) * | 1996-09-20 | 1998-03-26 | Board Of Regents, The University Of Texas System | Compositions and methods comprising bard1 and other brca1 binding proteins |
| CN1308347C (zh) * | 1999-04-28 | 2007-04-04 | 德克萨斯大学董事会 | 用于通过选择性抑制vegf来治疗癌症的组合物和方法 |
-
2000
- 2000-09-01 FR FR0011207A patent/FR2813606B1/fr not_active Expired - Fee Related
-
2001
- 2001-09-03 DE DE60120187T patent/DE60120187T2/de not_active Expired - Lifetime
- 2001-09-03 EP EP01967422A patent/EP1313855B1/fr not_active Expired - Lifetime
- 2001-09-03 CA CA2421258A patent/CA2421258C/fr not_active Expired - Fee Related
- 2001-09-03 US US10/363,285 patent/US7566764B2/en not_active Expired - Lifetime
- 2001-09-03 JP JP2002524039A patent/JP4995399B2/ja not_active Expired - Fee Related
- 2001-09-03 WO PCT/FR2001/002731 patent/WO2002018536A2/fr not_active Ceased
- 2001-09-03 AT AT01967422T patent/ATE328082T1/de active
-
2009
- 2009-06-23 US US12/489,893 patent/US20100016228A1/en not_active Abandoned
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