JP2001508762A - 架橋した外殻領域および内部芯領域を有する両親媒性コポリマーからなり、医薬およびその他の用途に有用な粒子 - Google Patents

架橋した外殻領域および内部芯領域を有する両親媒性コポリマーからなり、医薬およびその他の用途に有用な粒子

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Publication number
JP2001508762A
JP2001508762A JP50359098A JP50359098A JP2001508762A JP 2001508762 A JP2001508762 A JP 2001508762A JP 50359098 A JP50359098 A JP 50359098A JP 50359098 A JP50359098 A JP 50359098A JP 2001508762 A JP2001508762 A JP 2001508762A
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JP
Japan
Prior art keywords
poly
particles
acid
methacrylate
amphiphilic
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Pending
Application number
JP50359098A
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English (en)
Japanese (ja)
Inventor
ウーリイ,カレン,エル.
セカンド サーモンド,ケイ.,ブルース,ザ
ファン,ハイヨン
ウォーナー,ジェームズ,エム.
Original Assignee
ジー.ディー.サール アンド カンパニー
ザ ワシントン ユニバーシティ
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Application filed by ジー.ディー.サール アンド カンパニー, ザ ワシントン ユニバーシティ filed Critical ジー.ディー.サール アンド カンパニー
Publication of JP2001508762A publication Critical patent/JP2001508762A/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5138Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00Processes of treating or compounding macromolecular substances
    • C08J3/24Crosslinking, e.g. vulcanising, of macromolecules
    • C08J3/246Intercrosslinking of at least two polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991Coated
    • Y10T428/2998Coated including synthetic resin or polymer

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Nanotechnology (AREA)
  • Polymers & Plastics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicinal Preparation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Steroid Compounds (AREA)
JP50359098A 1996-06-27 1997-06-27 架橋した外殻領域および内部芯領域を有する両親媒性コポリマーからなり、医薬およびその他の用途に有用な粒子 Pending JP2001508762A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2069396P 1996-06-27 1996-06-27
US60/020,693 1996-06-27
PCT/US1997/011345 WO1997049387A1 (en) 1996-06-27 1997-06-27 Particles comprising amphiphilic copolymers, having a cross-linked shell domain and an interior core domain, useful for pharmaceutical and other applications

Publications (1)

Publication Number Publication Date
JP2001508762A true JP2001508762A (ja) 2001-07-03

Family

ID=21800036

Family Applications (2)

Application Number Title Priority Date Filing Date
JP10503615A Pending JP2000514791A (ja) 1996-06-27 1997-06-27 架橋した外殻領域および内部芯領域を有する両親媒性コポリマーからなり、医薬およびその他の用途に有用な粒子
JP50359098A Pending JP2001508762A (ja) 1996-06-27 1997-06-27 架橋した外殻領域および内部芯領域を有する両親媒性コポリマーからなり、医薬およびその他の用途に有用な粒子

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP10503615A Pending JP2000514791A (ja) 1996-06-27 1997-06-27 架橋した外殻領域および内部芯領域を有する両親媒性コポリマーからなり、医薬およびその他の用途に有用な粒子

Country Status (6)

Country Link
US (2) US6383500B1 (US06491903-20021210-C00058.png)
EP (2) EP0910351A1 (US06491903-20021210-C00058.png)
JP (2) JP2000514791A (US06491903-20021210-C00058.png)
AU (2) AU3649697A (US06491903-20021210-C00058.png)
CA (2) CA2258851A1 (US06491903-20021210-C00058.png)
WO (2) WO1997049387A1 (US06491903-20021210-C00058.png)

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WO2006073061A1 (ja) * 2004-12-17 2006-07-13 Mitsubishi Chemical Corporation 新規なコアーシェル構造体
JP2007524414A (ja) * 2004-02-02 2007-08-30 インターナショナル・ユニヴァーシティ・ブレーメン・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 液状媒体から物質を分離するための小胞
JP2007531774A (ja) * 2004-03-30 2007-11-08 イリプサ, インコーポレイテッド イオン結合ポリマーとその利用
JP2008517899A (ja) * 2004-10-25 2008-05-29 セロノヴァ バイオサイエンスィズ ジャーマニー ゲーエムベーハー 治療適用および/または診断適用のための充填可能なポリホスファゼン含有粒子、ならびにその調製方法および使用方法
JP2008533116A (ja) * 2005-03-18 2008-08-21 シンジェンタ リミテッド 製剤
JP2009269998A (ja) * 2008-05-07 2009-11-19 Osaka Prefecture Univ ヘッド−テイル型共重合体の中空ナノ微粒子
JP2012025783A (ja) * 2004-03-30 2012-02-09 Ilypsa Inc イオン結合ポリマーとその利用
JP2016052613A (ja) * 2014-09-02 2016-04-14 国立大学法人 千葉大学 コアシェル粒子
US11034786B2 (en) 2016-06-16 2021-06-15 Lg Chem, Ltd. Amphiphilic triblock polymer

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