ES2096150T3 - Copolimeros vinilicos reticulados, procedimiento para su preparacion, asi como el empleo de estos compuestos. - Google Patents

Copolimeros vinilicos reticulados, procedimiento para su preparacion, asi como el empleo de estos compuestos.

Info

Publication number
ES2096150T3
ES2096150T3 ES93111376T ES93111376T ES2096150T3 ES 2096150 T3 ES2096150 T3 ES 2096150T3 ES 93111376 T ES93111376 T ES 93111376T ES 93111376 T ES93111376 T ES 93111376T ES 2096150 T3 ES2096150 T3 ES 2096150T3
Authority
ES
Spain
Prior art keywords
compounds
preparation
vinyl copolymers
procedure
well
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93111376T
Other languages
English (en)
Inventor
Michael Dr Ahlers
Heiner Dr Glombik
Stefan Dr Mullner
Axel Dr Walch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2096150T3 publication Critical patent/ES2096150T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F259/00Macromolecular compounds obtained by polymerising monomers on to polymers of halogen containing monomers as defined in group C08F14/00
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/12Hydrolysis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2810/00Chemical modification of a polymer
    • C08F2810/20Chemical modification of a polymer leading to a crosslinking, either explicitly or inherently

Abstract

SE DESCRIBEN COPOLIMEROS DE VINILO, RETICULADOS, CONTENIENDO NITROGENO Y CON UNIDADES DE FORMULA (I) Y SUS SALES TOLERABLES FISIOLOGICAMENTE, UN PROCEDIMIENTO PARA SU APLICACION Y LA APLICACION DEL COMPUESTO COMO MEDICAMENTO, PORTADOR ACTIVO Y SUSTANCIAS AUXILIARES DE ALIMENTACION. TENIENDO A1, A2, R, W, X, Y Y Z UN SIGNIFICADO DESCRITO EN LA PATENTE.
ES93111376T 1992-07-22 1993-07-15 Copolimeros vinilicos reticulados, procedimiento para su preparacion, asi como el empleo de estos compuestos. Expired - Lifetime ES2096150T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4224110 1992-07-22

Publications (1)

Publication Number Publication Date
ES2096150T3 true ES2096150T3 (es) 1997-03-01

Family

ID=6463789

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93111376T Expired - Lifetime ES2096150T3 (es) 1992-07-22 1993-07-15 Copolimeros vinilicos reticulados, procedimiento para su preparacion, asi como el empleo de estos compuestos.

Country Status (16)

Country Link
US (2) US5428112A (es)
EP (1) EP0580079B1 (es)
JP (1) JPH06157671A (es)
KR (1) KR940005692A (es)
AT (1) ATE146193T1 (es)
AU (1) AU659562B2 (es)
CA (1) CA2101010A1 (es)
DE (1) DE59304725D1 (es)
DK (1) DK0580079T3 (es)
ES (1) ES2096150T3 (es)
FI (1) FI933274A (es)
GR (1) GR3022135T3 (es)
IL (1) IL106421A (es)
NO (1) NO301018B1 (es)
NZ (1) NZ248193A (es)
ZA (1) ZA935267B (es)

Families Citing this family (32)

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US6129910A (en) * 1993-06-02 2000-10-10 Geltex Pharmaceuticals, Inc. Water-insoluble noncrosslinked bile acid sequestrants
US5929184A (en) * 1993-06-02 1999-07-27 Geltex Pharmaceuticals, Inc. Hydrophilic nonamine-containing and amine-containing copolymers and their use as bile acid sequestrants
US5607669A (en) * 1994-06-10 1997-03-04 Geltex Pharmaceuticals, Inc. Amine polymer sequestrant and method of cholesterol depletion
US5618530A (en) * 1994-06-10 1997-04-08 Geltex Pharmaceuticals, Inc. Hydrophobic amine polymer sequestrant and method of cholesterol depletion
US5900475A (en) * 1994-06-10 1999-05-04 Geltex Pharmaceuticals, Inc. Hydrophobic sequestrant for cholesterol depletion
US5667775A (en) * 1993-08-11 1997-09-16 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US5414068A (en) * 1994-01-24 1995-05-09 Rohm And Haas Company Crosslinked anion exchange particles and method for producing the particles
TW474813B (en) * 1994-06-10 2002-02-01 Geltex Pharma Inc Alkylated composition for removing bile salts from a patient
DE19520092A1 (de) * 1995-06-01 1996-12-05 Bayer Ag Verfahren zur Papierveredlung unter Verwendung von Polyisocyanaten mit anionischen Gruppen
AU3585397A (en) 1996-06-27 1998-01-14 G.D. Searle & Co. Particles comprising amphiphilic copolymers, having a cross-linked shell domain and an interior core domain, useful for pharmaceutical and other applications
DE19633268A1 (de) * 1996-08-19 1998-02-26 Hoechst Ag Polymere Gallensäure-Resorptionsinhibitoren mit gleichzeitiger Gallensäure-Adsorberwirkung
US6203785B1 (en) * 1996-12-30 2001-03-20 Geltex Pharmaceuticals, Inc. Poly(diallylamine)-based bile acid sequestrants
DE19705992A1 (de) * 1997-02-17 1998-08-20 Basf Ag Verfahren zur Herstellung von Carbamateinheiten enthaltenden Polymerisaten und ihre Verwendung
US5925379A (en) * 1997-03-27 1999-07-20 Geltex Pharmaceuticals, Inc. Interpenetrating polymer networks for sequestration of bile acids
US6423754B1 (en) 1997-06-18 2002-07-23 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with polyallylamine polymers
FR2766194A1 (fr) * 1997-07-21 1999-01-22 Transgene Sa Polymeres cationiques, complexes associant lesdits polymeres cationiques et des substances therapeutiquement actives comprenant au moins une charge negative, notamment des acides nucleiques, et leur utilisation en therapie genique
FR2766195A1 (fr) 1997-07-21 1999-01-22 Transgene Sa Polymeres cationiques, complexes associant lesdits polymeres cationiques et des substances therapeutiquement actives comprenant au moins une charges negative, notamment des acides nucleiques, et leur utilisation en therapie genique
US6083497A (en) 1997-11-05 2000-07-04 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders
US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
AT409630B (de) * 2000-12-13 2002-09-25 Dsm Fine Chem Austria Gmbh Alkylierung von n-bzw. amino- oder ammoniumgruppen haltigen, vernetzten polymeren
CA2467737A1 (en) * 2001-12-21 2003-07-03 Ciba Specialty Chemicals Holding Inc. Poly(vinyl alcohol)-co-poly(n-vinyl formamide) copolymers
ATE420900T1 (de) 2001-12-21 2009-01-15 Ciba Holding Inc Polyvinylalkohol-co-polyinylamin-polymere mit funktionellen gruppen
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
JP2008526771A (ja) * 2004-12-30 2008-07-24 ジェンザイム コーポレーション 高リン酸血症のための亜鉛含有処置
JP2009507019A (ja) * 2005-09-02 2009-02-19 ジェンザイム・コーポレーション リン酸塩を除去する方法およびそれに使用される重合体
CN101272762B (zh) 2005-09-15 2013-02-06 基酶有限公司 胺聚合物的小袋制剂
WO2007056405A2 (en) * 2005-11-08 2007-05-18 Genzyme Corporation Magnesium-containing polymers for the treatment of hyperphosphatemia
JP2009542653A (ja) * 2006-07-05 2009-12-03 ジェンザイム コーポレーション リン酸塩過剰血症のための鉄(ii)含有治療剤
KR101822608B1 (ko) 2010-02-24 2018-01-29 리립사, 인크. 담즙산 격리제로서 사용하기 위한 아민 폴리머
WO2011106542A2 (en) 2010-02-24 2011-09-01 Relypsa, Inc. Crosslinked polyvrnylamine, poly all ylamine, and polyethyleneimine for use as bile acid sequestrants
MA41202A (fr) 2014-12-18 2017-10-24 Genzyme Corp Copolymères polydiallymine réticulé pour le traitement du diabète de type 2

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3558581A (en) * 1967-10-20 1971-01-26 Hoechst Ag Process for the manufacture of polyvinylmethylamines
US4238579A (en) * 1979-05-18 1980-12-09 Dynapol Vinylamine aromatic copolymers and salts thereof
DE3213873A1 (de) * 1982-04-15 1983-10-27 Basf Ag, 6700 Ludwigshafen Flockungsmittel fuer schlaemme
DE3128478A1 (de) * 1981-07-18 1983-02-03 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von linearen, basischen polymerisaten
FI70230C (fi) * 1981-07-18 1986-09-15 Basf Ag Rakkedjiga basiska polymerisat foerfarande foer deras framstaellning och deras anvaendning
EP0162388B1 (en) * 1984-05-11 1989-09-13 Bristol-Myers Company Novel bile sequestrant resin and uses
DE3534273A1 (de) * 1985-09-26 1987-04-02 Basf Ag Verfahren zur herstellung von vinylamin-einheiten enthaltenden wasserloeslichen copolymerisaten und deren verwendung als nass- und trockenverfestigungsmittel fuer papier
NL8502882A (nl) * 1985-10-22 1987-05-18 Stork Friesland Bv Werkwijze voor de bereiding van een n-vinyl-n-alkilamine (co) polymeer en samengesteld membraan vervaardigd onder toepassing van dit (co) polymeer.
CA1330684C (en) * 1988-04-15 1994-07-12 Robert Krantz Pinschmidt Jr. Method for preparing poly(vinyl alcohol)- co-poly(vinylamine) via a two-phase process
DE3901527A1 (de) * 1989-01-20 1990-07-26 Hoechst Ag Alkylierte polyethyleniminderivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel sowie pharmazeutische praeparate
DE4007312C2 (de) * 1990-03-08 2000-04-27 Basf Ag Verfahren zur Herstellung von feinteiligen, wasserlöslichen, Vinylamin-Einheiten enthaltenden Polymerisaten

Also Published As

Publication number Publication date
IL106421A (en) 1996-11-14
GR3022135T3 (en) 1997-03-31
ZA935267B (en) 1994-04-18
NO301018B1 (no) 1997-09-01
EP0580079A1 (de) 1994-01-26
FI933274A (fi) 1994-01-23
US5631326A (en) 1997-05-20
AU4208993A (en) 1994-01-27
NZ248193A (en) 1995-04-27
CA2101010A1 (en) 1994-01-23
DK0580079T3 (da) 1997-06-30
US5428112A (en) 1995-06-27
KR940005692A (ko) 1994-03-22
NO932635D0 (no) 1993-07-21
IL106421A0 (en) 1993-11-15
JPH06157671A (ja) 1994-06-07
EP0580079B1 (de) 1996-12-11
NO932635L (no) 1994-01-24
ATE146193T1 (de) 1996-12-15
DE59304725D1 (de) 1997-01-23
AU659562B2 (en) 1995-05-18
FI933274A0 (fi) 1993-07-20

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