JP2001504828A - 制御型放出システムの調製方法 - Google Patents
制御型放出システムの調製方法Info
- Publication number
- JP2001504828A JP2001504828A JP52350298A JP52350298A JP2001504828A JP 2001504828 A JP2001504828 A JP 2001504828A JP 52350298 A JP52350298 A JP 52350298A JP 52350298 A JP52350298 A JP 52350298A JP 2001504828 A JP2001504828 A JP 2001504828A
- Authority
- JP
- Japan
- Prior art keywords
- polymer
- phase
- cross
- water
- microspheres
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1664—Compounds of unknown constitution, e.g. material from plants or animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Botany (AREA)
- Zoology (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96203234.8 | 1996-11-19 | ||
| EP96203234A EP0842657A1 (en) | 1996-11-19 | 1996-11-19 | Microspheres for controlled release and processes to prepare these microspheres |
| PCT/NL1997/000625 WO1998022093A1 (en) | 1996-11-19 | 1997-11-17 | Process for the preparation of a controlled release system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001504828A true JP2001504828A (ja) | 2001-04-10 |
| JP2001504828A5 JP2001504828A5 (enExample) | 2004-09-02 |
Family
ID=8224598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP52350298A Ceased JP2001504828A (ja) | 1996-11-19 | 1997-11-17 | 制御型放出システムの調製方法 |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US6303148B1 (enExample) |
| EP (1) | EP0842657A1 (enExample) |
| JP (1) | JP2001504828A (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005506893A (ja) * | 2000-06-23 | 2005-03-10 | 金 拓 | 安定な水性/水性型乳化系とその使用 |
| KR20180030033A (ko) | 2015-07-13 | 2018-03-21 | 코스메드 파마소티컬 씨오 쩜 엘티디 | 약물 서방성 담체 및 그의 제조 방법 |
Families Citing this family (99)
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| US6395302B1 (en) * | 1996-11-19 | 2002-05-28 | Octoplus B.V. | Method for the preparation of microspheres which contain colloidal systems |
| US6153211A (en) * | 1997-07-18 | 2000-11-28 | Infimed, Inc. | Biodegradable macromers for the controlled release of biologically active substances |
| PT901786E (pt) | 1997-08-11 | 2007-08-07 | Pfizer Prod Inc | Disperções farmacêuticas sólidas com biodisponibilidade melhorada |
| PT1019111E (pt) | 1998-04-27 | 2002-10-31 | Surmodics Inc | Revestimento que liberta um agente bioactivo |
| EP1074248A1 (en) | 1999-07-08 | 2001-02-07 | Arnold Hilgers | Delivery system for biological material |
| US6699470B1 (en) * | 1999-10-12 | 2004-03-02 | Massachusetts Institute Of Technology | Mesh-gel constructs for cell delivery containing enzymes and/or enzyme inhibitors to control gel degradation |
| EP1306127B2 (en) * | 2001-10-26 | 2011-09-07 | OctoPlus PolyActive Sciences B.V. | Method for the preparation of purified microparticles |
| WO2003051113A1 (en) * | 2001-12-14 | 2003-06-26 | The University Of Wyoming | Methods and compositions for controlled release of drugs |
| US7097850B2 (en) | 2002-06-18 | 2006-08-29 | Surmodics, Inc. | Bioactive agent release coating and controlled humidity method |
| EP1393718A1 (en) * | 2002-08-29 | 2004-03-03 | OctoPlus Sciences B.V. | Colloidal drug carrier system |
| WO2004078198A1 (en) * | 2003-03-04 | 2004-09-16 | The Technology Development Company Ltd. | Long acting injectable insulin composition and methods of making and using thereof |
| US8545830B2 (en) * | 2003-03-24 | 2013-10-01 | University Of Tennessee Research Foundation | Multi-functional polymeric materials and their uses |
| TWI293317B (en) * | 2003-12-31 | 2008-02-11 | Ind Tech Res Inst | Method for preparing polymer microspheres by aqueous phase-aqueous phase emulsion process |
| EP1576952A1 (en) * | 2004-03-18 | 2005-09-21 | OctoPlus Technologies B.V. | Hydrogel microspheres with improved release profile |
| CN1964749A (zh) | 2004-04-06 | 2007-05-16 | 苏莫迪克斯公司 | 用于生物活性剂的涂料组合物 |
| WO2005113034A1 (en) * | 2004-05-12 | 2005-12-01 | Surmodics, Inc. | Natural biodegradable polysaccharides coatings for medical articles |
| US20070258939A1 (en) * | 2004-08-03 | 2007-11-08 | Biocamparibles Uk Limited | Drug Delivery from Embolic Agents |
| US7597884B2 (en) | 2004-08-09 | 2009-10-06 | Alios Biopharma, Inc. | Hyperglycosylated polypeptide variants and methods of use |
| US20060141021A1 (en) * | 2004-12-29 | 2006-06-29 | Industrial Technology Research | Polymeric microspheres and method for preparing the same |
| WO2007025441A1 (en) * | 2005-08-29 | 2007-03-08 | Tuo Jin | Polysaccharide microparticles containing biological agents: there preparation and applications |
| CA2621595A1 (en) * | 2005-09-21 | 2007-04-12 | Surmodics, Inc. | Coatings and articles including natural biodegradable polysaccharides |
| WO2007038126A1 (en) * | 2005-09-21 | 2007-04-05 | Surmodics, Inc. | In vivo formed matrices including natural biodegradable polysaccharides and ophthalmic uses thereof |
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| CA2841386A1 (en) | 2005-12-30 | 2007-07-12 | Zensun (Shanghai) Science & Technology Limited | Extended release of neuregulin for improved cardiac function |
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| US8968782B2 (en) * | 2006-06-28 | 2015-03-03 | Surmodics, Inc. | Combination degradable and non-degradable matrices for active agent delivery |
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| EP2091623A4 (en) * | 2006-11-17 | 2011-10-12 | Gareth Michael Forde | MATERIALS, METHODS AND SYSTEMS FOR PURIFICATION AND / OR SEPARATION OF MOLECULES |
| US20080154241A1 (en) * | 2006-12-07 | 2008-06-26 | Burkstrand Michael J | Latent stabilization of bioactive agents releasable from implantable medical articles |
| CN100471542C (zh) * | 2006-12-15 | 2009-03-25 | 中国科学院长春应用化学研究所 | 一种分离超细微粒的工艺 |
| US8821899B2 (en) * | 2007-03-12 | 2014-09-02 | Board Of Regents, The University Of Texas System | Method and process for the production of multi-coated recognitive and releasing systems |
| US8771713B2 (en) * | 2007-03-12 | 2014-07-08 | Board Of Regents, The University Of Texas System | Method and process for the production of multi-coated recognitive and releasing systems |
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| CA2695374A1 (en) * | 2007-08-15 | 2009-02-19 | Amunix, Inc. | Compositions and methods for modifying properties of biologically active polypeptides |
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| JP2011509944A (ja) * | 2008-01-14 | 2011-03-31 | サーモディクス,インコーポレイティド | 核酸送達複合体の溶出のための装置及び方法 |
| US7748452B2 (en) * | 2008-02-19 | 2010-07-06 | Schlumberger Technology Corporation | Polymeric microspheres as degradable fluid loss additives in oilfield applications |
| WO2009120361A2 (en) | 2008-03-28 | 2009-10-01 | Surmodics, Inc. | Insertable medical devices having microparticulate-associated elastic substrates and methods for drug delivery |
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| US20110118189A1 (en) | 2008-04-28 | 2011-05-19 | Farr Stephen J | Novel formulations for treatment of migraine |
| JP5763525B2 (ja) * | 2008-05-07 | 2015-08-12 | サーモディクス,インコーポレイティド | 粒子からの核酸複合体の送達 |
| EP2306929A1 (en) * | 2008-07-14 | 2011-04-13 | SurModics, Inc. | Medical devices and methods for delivery of nucleic acids |
| DK3178835T3 (da) | 2009-02-03 | 2019-06-24 | Amunix Pharmaceuticals Inc | Forlængede rekombinante polypeptider og sammensætninger omfattende samme |
| WO2010102065A1 (en) | 2009-03-05 | 2010-09-10 | Bend Research, Inc. | Pharmaceutical compositions of dextran polymer derivatives |
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| US20110046721A1 (en) * | 2009-08-10 | 2011-02-24 | Surmodics, Inc. | Biodegradable Metal-Polymer Composite Constructs For Implantable Medical Devices |
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| EP3841086B1 (en) | 2018-08-20 | 2025-04-23 | Achillion Pharmaceuticals, Inc. | Pharmaceutical compounds for the treatment of complement factor d medical disorders |
| JP7443375B2 (ja) | 2018-09-06 | 2024-03-05 | アキリオン ファーマシューティカルズ, インコーポレーテッド | 医学的障害の治療のための大環状化合物 |
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| CN114845708A (zh) | 2019-12-19 | 2022-08-02 | 乔治亚州大学研究基金会 | 用于治疗细菌感染和增强抗生素的化合物 |
| JP2023515073A (ja) | 2020-02-20 | 2023-04-12 | アキリオン ファーマシューティカルズ, インコーポレーテッド | 補体因子d媒介障害の処置用のヘテロアリール化合物 |
| CA3193488A1 (en) | 2020-09-23 | 2022-03-31 | Jason Allan Wiles | Pharmaceutical compounds for the treatment of complement mediated disorders |
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Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4963367A (en) * | 1984-04-27 | 1990-10-16 | Medaphore, Inc. | Drug delivery compositions and methods |
| SE459005B (sv) * | 1985-07-12 | 1989-05-29 | Aake Rikard Lindahl | Saett att framstaella sfaeriska polymerpartiklar |
| US5783214A (en) * | 1994-06-13 | 1998-07-21 | Buford Biomedical, Inc. | Bio-erodible matrix for the controlled release of medicinals |
| US5603955A (en) * | 1994-07-18 | 1997-02-18 | University Of Cincinnati | Enhanced loading of solutes into polymer gels |
| IT1268718B1 (it) * | 1994-07-26 | 1997-03-06 | Fidia Advanced Biopolymers Srl | Sintesi di gel chimici da polisaccaridi polielettroliti tramite gamma irradiazione |
| US5827707A (en) * | 1995-06-07 | 1998-10-27 | Neocrin Company | Method for manufacturing minimal volume capsules containing biological materials |
| US5980948A (en) * | 1996-08-16 | 1999-11-09 | Osteotech, Inc. | Polyetherester copolymers as drug delivery matrices |
-
1996
- 1996-11-19 EP EP96203234A patent/EP0842657A1/en not_active Withdrawn
-
1997
- 1997-11-17 JP JP52350298A patent/JP2001504828A/ja not_active Ceased
- 1997-11-17 US US09/308,349 patent/US6303148B1/en not_active Expired - Lifetime
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005506893A (ja) * | 2000-06-23 | 2005-03-10 | 金 拓 | 安定な水性/水性型乳化系とその使用 |
| KR20180030033A (ko) | 2015-07-13 | 2018-03-21 | 코스메드 파마소티컬 씨오 쩜 엘티디 | 약물 서방성 담체 및 그의 제조 방법 |
Also Published As
| Publication number | Publication date |
|---|---|
| US6303148B1 (en) | 2001-10-16 |
| EP0842657A1 (en) | 1998-05-20 |
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