|
US6395302B1
(en)
*
|
1996-11-19 |
2002-05-28 |
Octoplus B.V. |
Method for the preparation of microspheres which contain colloidal systems
|
|
US6153211A
(en)
*
|
1997-07-18 |
2000-11-28 |
Infimed, Inc. |
Biodegradable macromers for the controlled release of biologically active substances
|
|
PT901786E
(pt)
|
1997-08-11 |
2007-08-07 |
Pfizer Prod Inc |
Disperções farmacêuticas sólidas com biodisponibilidade melhorada
|
|
PT1019111E
(pt)
|
1998-04-27 |
2002-10-31 |
Surmodics Inc |
Revestimento que liberta um agente bioactivo
|
|
EP1074248A1
(en)
|
1999-07-08 |
2001-02-07 |
Arnold Hilgers |
Delivery system for biological material
|
|
US6699470B1
(en)
*
|
1999-10-12 |
2004-03-02 |
Massachusetts Institute Of Technology |
Mesh-gel constructs for cell delivery containing enzymes and/or enzyme inhibitors to control gel degradation
|
|
US6805879B2
(en)
*
|
2000-06-23 |
2004-10-19 |
Biopharm Solutions Inc. |
Stable polymer aqueous/aqueous emulsion system and uses thereof
|
|
EP1306127B2
(en)
*
|
2001-10-26 |
2011-09-07 |
OctoPlus PolyActive Sciences B.V. |
Method for the preparation of purified microparticles
|
|
WO2003051113A1
(en)
*
|
2001-12-14 |
2003-06-26 |
The University Of Wyoming |
Methods and compositions for controlled release of drugs
|
|
US7097850B2
(en)
|
2002-06-18 |
2006-08-29 |
Surmodics, Inc. |
Bioactive agent release coating and controlled humidity method
|
|
EP1393718A1
(en)
*
|
2002-08-29 |
2004-03-03 |
OctoPlus Sciences B.V. |
Colloidal drug carrier system
|
|
WO2004078198A1
(en)
*
|
2003-03-04 |
2004-09-16 |
The Technology Development Company Ltd. |
Long acting injectable insulin composition and methods of making and using thereof
|
|
US8545830B2
(en)
*
|
2003-03-24 |
2013-10-01 |
University Of Tennessee Research Foundation |
Multi-functional polymeric materials and their uses
|
|
TWI293317B
(en)
*
|
2003-12-31 |
2008-02-11 |
Ind Tech Res Inst |
Method for preparing polymer microspheres by aqueous phase-aqueous phase emulsion process
|
|
EP1576952A1
(en)
*
|
2004-03-18 |
2005-09-21 |
OctoPlus Technologies B.V. |
Hydrogel microspheres with improved release profile
|
|
CN1964749A
(zh)
|
2004-04-06 |
2007-05-16 |
苏莫迪克斯公司 |
用于生物活性剂的涂料组合物
|
|
WO2005113034A1
(en)
*
|
2004-05-12 |
2005-12-01 |
Surmodics, Inc. |
Natural biodegradable polysaccharides coatings for medical articles
|
|
US20070258939A1
(en)
*
|
2004-08-03 |
2007-11-08 |
Biocamparibles Uk Limited |
Drug Delivery from Embolic Agents
|
|
US7597884B2
(en)
|
2004-08-09 |
2009-10-06 |
Alios Biopharma, Inc. |
Hyperglycosylated polypeptide variants and methods of use
|
|
US20060141021A1
(en)
*
|
2004-12-29 |
2006-06-29 |
Industrial Technology Research |
Polymeric microspheres and method for preparing the same
|
|
WO2007025441A1
(en)
*
|
2005-08-29 |
2007-03-08 |
Tuo Jin |
Polysaccharide microparticles containing biological agents: there preparation and applications
|
|
CA2621595A1
(en)
*
|
2005-09-21 |
2007-04-12 |
Surmodics, Inc. |
Coatings and articles including natural biodegradable polysaccharides
|
|
WO2007038126A1
(en)
*
|
2005-09-21 |
2007-04-05 |
Surmodics, Inc. |
In vivo formed matrices including natural biodegradable polysaccharides and ophthalmic uses thereof
|
|
US20090099031A1
(en)
*
|
2005-09-27 |
2009-04-16 |
Stemmer Willem P |
Genetic package and uses thereof
|
|
US7855279B2
(en)
*
|
2005-09-27 |
2010-12-21 |
Amunix Operating, Inc. |
Unstructured recombinant polymers and uses thereof
|
|
US7846445B2
(en)
*
|
2005-09-27 |
2010-12-07 |
Amunix Operating, Inc. |
Methods for production of unstructured recombinant polymers and uses thereof
|
|
AU2006294644A1
(en)
*
|
2005-09-27 |
2007-04-05 |
Amunix, Inc. |
Proteinaceous pharmaceuticals and uses thereof
|
|
WO2007059144A1
(en)
*
|
2005-11-15 |
2007-05-24 |
Surmodics, Inc. |
Ultrasonic nozzles for applying two-component coatings
|
|
EP1948271B1
(en)
|
2005-11-17 |
2013-10-02 |
Zogenix, Inc. |
Delivery of viscous formulations by needle-free injection
|
|
CA2841386A1
(en)
|
2005-12-30 |
2007-07-12 |
Zensun (Shanghai) Science & Technology Limited |
Extended release of neuregulin for improved cardiac function
|
|
US20080039931A1
(en)
*
|
2006-04-25 |
2008-02-14 |
Surmodics, Inc. |
Hydrophilic shape memory insertable medical articles
|
|
JP2009542671A
(ja)
*
|
2006-06-28 |
2009-12-03 |
サーモディクス，インコーポレイティド |
微粒子を含む活性剤溶出マトリックス
|
|
US8968782B2
(en)
*
|
2006-06-28 |
2015-03-03 |
Surmodics, Inc. |
Combination degradable and non-degradable matrices for active agent delivery
|
|
WO2008022258A2
(en)
*
|
2006-08-16 |
2008-02-21 |
Surmodics, Inc. |
Methods and materials for increasing the adhesion of elution control matrices to substrates
|
|
US20080075753A1
(en)
*
|
2006-09-25 |
2008-03-27 |
Chappa Ralph A |
Multi-layered coatings and methods for controlling elution of active agents
|
|
WO2008088593A2
(en)
*
|
2006-09-27 |
2008-07-24 |
Surmodics, Inc. |
Additives and methods for enhancing active agent elution kinetics
|
|
EP2091623A4
(en)
*
|
2006-11-17 |
2011-10-12 |
Gareth Michael Forde |
MATERIALS, METHODS AND SYSTEMS FOR PURIFICATION AND / OR SEPARATION OF MOLECULES
|
|
US20080154241A1
(en)
*
|
2006-12-07 |
2008-06-26 |
Burkstrand Michael J |
Latent stabilization of bioactive agents releasable from implantable medical articles
|
|
CN100471542C
(zh)
*
|
2006-12-15 |
2009-03-25 |
中国科学院长春应用化学研究所 |
一种分离超细微粒的工艺
|
|
US8821899B2
(en)
*
|
2007-03-12 |
2014-09-02 |
Board Of Regents, The University Of Texas System |
Method and process for the production of multi-coated recognitive and releasing systems
|
|
US8771713B2
(en)
*
|
2007-03-12 |
2014-07-08 |
Board Of Regents, The University Of Texas System |
Method and process for the production of multi-coated recognitive and releasing systems
|
|
US9155703B2
(en)
*
|
2007-03-12 |
2015-10-13 |
Board Of Regents, The University Of Texas System |
Method and process for the production of multi-coated recognitive and releasing systems
|
|
US8741316B2
(en)
*
|
2007-03-12 |
2014-06-03 |
Board Of Regents, The University Of Texas System |
Highly porous, recognitive polymer systems
|
|
WO2008121750A2
(en)
*
|
2007-03-28 |
2008-10-09 |
Vance Products Incorporated D/B/A |
Medical device for delivering a bioactive and method of use thereof
|
|
JP5443976B2
(ja)
|
2007-05-01 |
2014-03-19 |
国立大学法人 東京医科歯科大学 |
化学架橋ヒアルロン酸誘導体を含むハイブリッドゲルおよびそれを用いた医薬組成物
|
|
EP2025334A1
(en)
*
|
2007-07-25 |
2009-02-18 |
OctoPlus Sciences B.V. |
Sustained release drug delivery system for repeated administration
|
|
CA2695374A1
(en)
*
|
2007-08-15 |
2009-02-19 |
Amunix, Inc. |
Compositions and methods for modifying properties of biologically active polypeptides
|
|
US20090214601A1
(en)
*
|
2007-09-28 |
2009-08-27 |
Chappa Ralph A |
Porous Drug Delivery Devices and Related Methods
|
|
JP2011509944A
(ja)
*
|
2008-01-14 |
2011-03-31 |
サーモディクス，インコーポレイティド |
核酸送達複合体の溶出のための装置及び方法
|
|
US7748452B2
(en)
*
|
2008-02-19 |
2010-07-06 |
Schlumberger Technology Corporation |
Polymeric microspheres as degradable fluid loss additives in oilfield applications
|
|
WO2009120361A2
(en)
|
2008-03-28 |
2009-10-01 |
Surmodics, Inc. |
Insertable medical devices having microparticulate-associated elastic substrates and methods for drug delivery
|
|
WO2009126830A2
(en)
*
|
2008-04-09 |
2009-10-15 |
Surmodics, Inc. |
Delivery of nucleic acid complexes from materials including negatively charged groups
|
|
US20110118189A1
(en)
|
2008-04-28 |
2011-05-19 |
Farr Stephen J |
Novel formulations for treatment of migraine
|
|
JP5763525B2
(ja)
*
|
2008-05-07 |
2015-08-12 |
サーモディクス，インコーポレイティド |
粒子からの核酸複合体の送達
|
|
EP2306929A1
(en)
*
|
2008-07-14 |
2011-04-13 |
SurModics, Inc. |
Medical devices and methods for delivery of nucleic acids
|
|
DK3178835T3
(da)
|
2009-02-03 |
2019-06-24 |
Amunix Pharmaceuticals Inc |
Forlængede rekombinante polypeptider og sammensætninger omfattende samme
|
|
WO2010102065A1
(en)
|
2009-03-05 |
2010-09-10 |
Bend Research, Inc. |
Pharmaceutical compositions of dextran polymer derivatives
|
|
PT3130396T
(pt)
|
2009-03-27 |
2021-05-12 |
Bend Res Inc |
Processo de secagem por pulverização
|
|
US20110046721A1
(en)
*
|
2009-08-10 |
2011-02-24 |
Surmodics, Inc. |
Biodegradable Metal-Polymer Composite Constructs For Implantable Medical Devices
|
|
CA2771999A1
(en)
|
2009-08-24 |
2011-03-10 |
Amunix Operating Inc. |
Coagulation factor vii compositions and methods of making and using same
|
|
BR112012009801A8
(pt)
|
2009-10-30 |
2016-08-30 |
Cns Therapeutics Inc |
Polipeptídeo neurturina e variante de neurturina
|
|
US20110159098A1
(en)
*
|
2009-12-30 |
2011-06-30 |
Surmodics, Inc. |
Stabilization and delivery of nucleic acid complexes
|
|
JP5984806B2
(ja)
|
2010-06-30 |
2016-09-06 |
サーモディクス，インコーポレイティド |
生体活性剤を送達する医療デバイスのための脂質コーティング
|
|
US8815294B2
(en)
|
2010-09-03 |
2014-08-26 |
Bend Research, Inc. |
Pharmaceutical compositions of dextran polymer derivatives and a carrier material
|
|
WO2012031133A2
(en)
|
2010-09-03 |
2012-03-08 |
Bench Research, Inc. |
Spray-drying apparatus and methods of using the same
|
|
WO2012031129A2
(en)
|
2010-09-03 |
2012-03-08 |
Bend Research, Inc. |
Spray-drying apparatus and methods of using the same
|
|
US9248584B2
(en)
|
2010-09-24 |
2016-02-02 |
Bend Research, Inc. |
High-temperature spray drying process and apparatus
|
|
US20120100187A1
(en)
|
2010-10-26 |
2012-04-26 |
Surmodics, Inc. |
Coatings and methods for controlled elution of hydrophilic active agents
|
|
US8901092B2
(en)
|
2010-12-29 |
2014-12-02 |
Surmodics, Inc. |
Functionalized polysaccharides for active agent delivery
|
|
US9060938B2
(en)
|
2011-05-10 |
2015-06-23 |
Bend Research, Inc. |
Pharmaceutical compositions of active agents and cationic dextran polymer derivatives
|
|
CN111548418A
(zh)
|
2012-02-15 |
2020-08-18 |
比奥贝拉蒂治疗公司 |
因子viii组合物及其制备和使用方法
|
|
WO2013123457A1
(en)
|
2012-02-15 |
2013-08-22 |
Biogen Idec Ma Inc. |
Recombinant factor viii proteins
|
|
CA2874824C
(en)
|
2012-06-01 |
2021-10-26 |
Surmodics, Inc. |
Apparatus and methods for coating balloon catheters
|
|
US9827401B2
(en)
|
2012-06-01 |
2017-11-28 |
Surmodics, Inc. |
Apparatus and methods for coating medical devices
|
|
US11090468B2
(en)
|
2012-10-25 |
2021-08-17 |
Surmodics, Inc. |
Apparatus and methods for coating medical devices
|
|
US10548953B2
(en)
|
2013-08-14 |
2020-02-04 |
Bioverativ Therapeutics Inc. |
Factor VIII-XTEN fusions and uses thereof
|
|
EA201691111A1
(ru)
|
2014-01-10 |
2017-01-30 |
Байоджен Ма Инк. |
Химерные белки фактора viii и их применение
|
|
WO2016115520A1
(en)
|
2015-01-16 |
2016-07-21 |
The J. David Gladstone Institutes |
Methods for treating tauopathy
|
|
CA2992258A1
(en)
|
2015-07-13 |
2017-01-19 |
Cosmed Pharmaceutical Co., Ltd. |
Drug sustained-release carrier and method for producing same
|
|
UA126016C2
(uk)
|
2015-08-03 |
2022-08-03 |
Біовератів Терапеутікс Інк. |
Злитий білок фактора іх
|
|
CN107921113B
(zh)
|
2015-08-25 |
2026-08-11 |
巴比塔·阿格拉沃尔 |
免疫调节组合物及其使用方法
|
|
AR106018A1
(es)
|
2015-08-26 |
2017-12-06 |
Achillion Pharmaceuticals Inc |
Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos
|
|
WO2017035408A1
(en)
|
2015-08-26 |
2017-03-02 |
Achillion Pharmaceuticals, Inc. |
Compounds for treatment of immune and inflammatory disorders
|
|
EP3205393A1
(en)
*
|
2016-02-12 |
2017-08-16 |
Basf Se |
Process for preparation of microcapsules
|
|
US10712240B2
(en)
|
2016-04-19 |
2020-07-14 |
Ariana Schanzer |
Contaminant monitor system and method
|
|
MX2018016046A
(es)
|
2016-06-27 |
2019-05-02 |
Achillion Pharmaceuticals Inc |
Quinazolina y compuestos indol para tratar trastornos medicos.
|
|
KR20190090827A
(ko)
|
2016-12-02 |
2019-08-02 |
바이오버라티브 테라퓨틱스 인크. |
키메라 응고 인자를 사용해 혈우병성 관절증을 치료하는 방법
|
|
CA3053818A1
(en)
|
2017-03-01 |
2018-09-07 |
Achillion Pharmaceuticals, Inc. |
Aryl, heteroaryl, and heterocyclic pharmaceutical compounds for treatment of medical disorders
|
|
KR102914074B1
(ko)
|
2018-05-18 |
2026-01-16 |
바이오버라티브 테라퓨틱스 인크. |
A형 혈우병의 치료 방법
|
|
EP3841086B1
(en)
|
2018-08-20 |
2025-04-23 |
Achillion Pharmaceuticals, Inc. |
Pharmaceutical compounds for the treatment of complement factor d medical disorders
|
|
JP7443375B2
(ja)
|
2018-09-06 |
2024-03-05 |
アキリオン ファーマシューティカルズ， インコーポレーテッド |
医学的障害の治療のための大環状化合物
|
|
CN113365617B
(zh)
|
2018-10-16 |
2025-12-23 |
乔治亚州立大学研究基金会股份有限公司 |
用于医学疾病治疗的一氧化碳前药
|
|
WO2020112816A1
(en)
|
2018-11-29 |
2020-06-04 |
Surmodics, Inc. |
Apparatus and methods for coating medical devices
|
|
MX2021011507A
(es)
|
2019-03-22 |
2021-12-15 |
Achillion Pharmaceuticals Inc |
Compuestos farmaceuticos para el tratamiento de trastornos mediados por complemento.
|
|
US11819590B2
(en)
|
2019-05-13 |
2023-11-21 |
Surmodics, Inc. |
Apparatus and methods for coating medical devices
|
|
CN114845708A
(zh)
|
2019-12-19 |
2022-08-02 |
乔治亚州大学研究基金会 |
用于治疗细菌感染和增强抗生素的化合物
|
|
JP2023515073A
(ja)
|
2020-02-20 |
2023-04-12 |
アキリオン ファーマシューティカルズ， インコーポレーテッド |
補体因子ｄ媒介障害の処置用のヘテロアリール化合物
|
|
CA3193488A1
(en)
|
2020-09-23 |
2022-03-31 |
Jason Allan Wiles |
Pharmaceutical compounds for the treatment of complement mediated disorders
|
|
US12496612B2
(en)
|
2021-01-08 |
2025-12-16 |
Surmodics, Inc. |
Coating application system and methods for coating rotatable medical devices
|
|
CN115109301A
(zh)
*
|
2021-03-18 |
2022-09-27 |
四川大学 |
一种中空开口二醋酸纤维素微球的制备方法
|
|
WO2025111713A1
(en)
*
|
2023-12-01 |
2025-06-05 |
Tsai Scott S H |
Systems and methods of isolation of extracellular vesicles
|