JP2001504331A5 - - Google Patents
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- Publication number
- JP2001504331A5 JP2001504331A5 JP1998521150A JP52115098A JP2001504331A5 JP 2001504331 A5 JP2001504331 A5 JP 2001504331A5 JP 1998521150 A JP1998521150 A JP 1998521150A JP 52115098 A JP52115098 A JP 52115098A JP 2001504331 A5 JP2001504331 A5 JP 2001504331A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9623236.8 | 1996-11-07 | ||
| GBGB9623236.8A GB9623236D0 (en) | 1996-11-07 | 1996-11-07 | Notch |
| GBGB9715674.9A GB9715674D0 (en) | 1997-07-24 | 1997-07-24 | Notch |
| GB9715674.9 | 1997-07-24 | ||
| GBGB9719350.2A GB9719350D0 (en) | 1997-09-11 | 1997-09-11 | Notch |
| GB9719350.2 | 1997-09-11 | ||
| PCT/GB1997/003058 WO1998020142A1 (en) | 1996-11-07 | 1997-11-06 | Notch |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2001504331A JP2001504331A (ja) | 2001-04-03 |
| JP2001504331A5 true JP2001504331A5 (enExample) | 2005-05-12 |
| JP4339406B2 JP4339406B2 (ja) | 2009-10-07 |
Family
ID=27268574
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP52115098A Expired - Fee Related JP4339406B2 (ja) | 1996-11-07 | 1997-11-06 | 免疫療法に使用する医薬の製造におけるＳｅｒｒａｔｅまたはＤｅｌｔａの使用 |
Country Status (20)
| Country | Link |
|---|---|
| EP (2) | EP0942998B1 (enExample) |
| JP (1) | JP4339406B2 (enExample) |
| KR (1) | KR100393234B1 (enExample) |
| CN (2) | CN1160371C (enExample) |
| AT (1) | ATE299184T1 (enExample) |
| AU (1) | AU736361B2 (enExample) |
| BG (1) | BG103444A (enExample) |
| CA (1) | CA2271248C (enExample) |
| CZ (1) | CZ295997B6 (enExample) |
| DE (1) | DE69733695T2 (enExample) |
| ES (1) | ES2243986T3 (enExample) |
| GB (2) | GB2353094B (enExample) |
| GE (1) | GEP20043390B (enExample) |
| IL (1) | IL129531A0 (enExample) |
| NO (1) | NO992196L (enExample) |
| NZ (1) | NZ335549A (enExample) |
| PL (1) | PL333302A1 (enExample) |
| RO (1) | RO120850B1 (enExample) |
| TR (1) | TR199901000T2 (enExample) |
| WO (1) | WO1998020142A1 (enExample) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2334953T3 (es) | 1995-06-28 | 2010-03-17 | Imperial Cancer Research Technology Limited | Secuencias de nucleotidos y proteinas de genes delta de vertebrados y metodos basados en los mismos. |
| US5780300A (en) * | 1995-09-29 | 1998-07-14 | Yale University | Manipulation of non-terminally differentiated cells using the notch pathway |
| GB9824045D0 (en) * | 1998-11-03 | 1998-12-30 | European Molecular Biology Lab Embl | Regulator protein |
| GB9827604D0 (en) * | 1998-12-15 | 1999-02-10 | Lorantis Ltd | Methods of immunosuppression |
| GB9927328D0 (en) * | 1999-11-18 | 2000-01-12 | Lorantis Ltd | Immunotherapy |
| GB0019242D0 (en) * | 2000-08-04 | 2000-09-27 | Lorantis Ltd | Assay |
| CA2422538C (en) * | 2000-09-22 | 2012-06-19 | Genentech, Inc. | Notch receptor agonists and uses |
| US6689744B2 (en) | 2000-09-22 | 2004-02-10 | Genentech, Inc. | Notch receptor agonists and uses |
| RU2179862C1 (ru) * | 2000-12-26 | 2002-02-27 | Общество с ограниченной ответственностью Научно-производственный центр "МедБиоСпектр" | Лекарственное средство для предотвращения отторжения трансплантата, моноклональное антитело к cd3-антигену т-лимфоцитов человека, гибридома и способ лечения больных, имеющих реакцию острого отторжения трансплантата после пересадки почки |
| CA2454937A1 (en) * | 2001-07-25 | 2003-02-13 | Lorantis Limited | Modulators of notch signalling for use in immunotherapy |
| GB0118155D0 (en) * | 2001-07-25 | 2001-09-19 | Lorantis Ltd | Superantigen |
| GB0123379D0 (en) * | 2001-09-28 | 2001-11-21 | Lorantis Ltd | Modulators |
| CA2475288C (en) * | 2002-02-06 | 2014-09-02 | Sanbio, Inc. | Method of inducing differentiation of bone marrow stromal cells to neural cells or skeletal muscle cells by introduction of notch gene |
| WO2003087159A2 (en) * | 2002-04-05 | 2003-10-23 | Lorantis Limited | Modulators of the notch signalling pathway and uses thereof in medical treatment |
| EP1525221A1 (en) * | 2002-08-03 | 2005-04-27 | Lorantis Limited | Conjugate of notch signalling pathway modulators and their use in medical treatment |
| GB0218879D0 (en) * | 2002-08-14 | 2002-09-25 | Lorantis Ltd | Medical treatment |
| GB0220658D0 (en) * | 2002-09-05 | 2002-10-16 | Lorantis Ltd | Immunotherapy |
| EP1549347A1 (en) * | 2002-10-09 | 2005-07-06 | Lorantis Limited | Modulation of immune function |
| WO2004060262A2 (en) * | 2003-01-07 | 2004-07-22 | Lorantis Limited | Modulators of notch signalling for use in immunotherpapy |
| GB0300428D0 (en) * | 2003-01-09 | 2003-02-05 | Lorantis Ltd | Medical treatment |
| WO2004064863A1 (en) * | 2003-01-23 | 2004-08-05 | Lorantis Limited | Treatment of autoimmune diseases using an activator for the notch signaling pathway |
| GB0303663D0 (en) * | 2003-02-18 | 2003-03-19 | Lorantis Ltd | Assays and medical treatments |
| WO2004083372A2 (en) * | 2003-03-21 | 2004-09-30 | Lorantis Limited | Modulators of the notch signaling pathway immobilized on particles for modifying immune responses |
| ATE474593T1 (de) * | 2003-03-21 | 2010-08-15 | Celldex Therapeutics Ltd | Behandlung von allergischen erkrankungen unter verwendung eines modulators des notch signaling pathway |
| GB0307472D0 (en) * | 2003-04-01 | 2003-05-07 | Lorantis Ltd | Medical treatment |
| JP2009539403A (ja) | 2006-06-13 | 2009-11-19 | オンコメッド ファーマシューティカルズ インコーポレイテッド | 癌を診断および処置するための組成物および方法 |
| WO2008091641A2 (en) | 2007-01-24 | 2008-07-31 | Oncomed Pharmaceuticals, Inc. | Compositions and methods for diagnosing and treating cancer |
| JP5560270B2 (ja) | 2008-07-08 | 2014-07-23 | オンコメッド ファーマシューティカルズ インコーポレイテッド | Ｎｏｔｃｈ結合剤およびアンタゴニストならびにその使用方法 |
| US9475855B2 (en) * | 2008-08-22 | 2016-10-25 | The Trustees Of Columbia University In The City Of New York | Human Notch3 based fusion proteins as decoy inhibitors of Notch3 signaling |
| WO2010091679A2 (de) * | 2009-02-16 | 2010-08-19 | Deutsches Rheuma-Forschungszentrum Berlin | Verwendung von notch-regulatoren zur modulation der immunantwort durch induktion/suppression von interleukin-22 |
| CN105131112A (zh) | 2009-08-29 | 2015-12-09 | Abbvie公司 | 治疗用dll4结合蛋白 |
| AU2011223919B2 (en) | 2010-03-02 | 2015-03-19 | Abbvie Inc. | Therapeutic DLL4 binding proteins |
| JP5932970B2 (ja) * | 2011-04-06 | 2016-06-08 | サンバイオ，インコーポレイティド | 末梢免疫機能を調節するための方法及び組成物 |
| WO2013074596A1 (en) * | 2011-11-16 | 2013-05-23 | Oncomed Pharmaceuticals, Inc. | Human notch receptor mutations and their use |
| US20150140043A1 (en) * | 2012-05-10 | 2015-05-21 | Institut National De La Sante De La Recherche Medical (Inserm) | Immunomodulatory methods using notch agonists |
| KR101573650B1 (ko) | 2015-02-04 | 2015-12-01 | 성균관대학교산학협력단 | Hcmv 바이러스 복제 억제용 조성물 |
| EP3844266A1 (en) * | 2018-08-28 | 2021-07-07 | Fred Hutchinson Cancer Research Center | Methods and compositions for adoptive t cell therapy incorporating induced notch signaling |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL101728A (en) * | 1991-05-03 | 2007-08-19 | Univ Yale | Human Abandonment and Delta, Restrictive Areas of Effect in Tophoric Proteins, and Methods Based on Them |
| US5869282A (en) * | 1991-12-11 | 1999-02-09 | Imperial Cancer Research Technology, Ltd. | Nucleotide and protein sequences of the serrate gene and methods based thereon |
| US5786158A (en) * | 1992-04-30 | 1998-07-28 | Yale University | Therapeutic and diagnostic methods and compositions based on notch proteins and nucleic acids |
| AU689214B2 (en) * | 1994-02-01 | 1998-03-26 | United States Of America, Represented By The Secretary, Department Of Health And Human Services, The | Fusion proteins that include antibody and nonantibody portions |
| US5780300A (en) * | 1995-09-29 | 1998-07-14 | Yale University | Manipulation of non-terminally differentiated cells using the notch pathway |
| US6337387B1 (en) * | 1995-11-17 | 2002-01-08 | Asahi Kasei Kabushiki Kaisha | Differentiation-suppressive polypeptide |
-
1997
- 1997-11-06 CZ CZ19991639A patent/CZ295997B6/cs not_active IP Right Cessation
- 1997-11-06 GB GB0023691A patent/GB2353094B/en not_active Expired - Fee Related
- 1997-11-06 GB GB9910276A patent/GB2335194B/en not_active Revoked
- 1997-11-06 AU AU48765/97A patent/AU736361B2/en not_active Ceased
- 1997-11-06 CN CNB971811598A patent/CN1160371C/zh not_active Expired - Fee Related
- 1997-11-06 CA CA002271248A patent/CA2271248C/en not_active Expired - Fee Related
- 1997-11-06 EP EP97911353A patent/EP0942998B1/en not_active Expired - Lifetime
- 1997-11-06 GE GE3531A patent/GEP20043390B/en unknown
- 1997-11-06 RO RO99-00524A patent/RO120850B1/ro unknown
- 1997-11-06 AT AT97911353T patent/ATE299184T1/de not_active IP Right Cessation
- 1997-11-06 EP EP05076507A patent/EP1616958A3/en not_active Withdrawn
- 1997-11-06 PL PL97333302A patent/PL333302A1/xx unknown
- 1997-11-06 WO PCT/GB1997/003058 patent/WO1998020142A1/en not_active Ceased
- 1997-11-06 IL IL12953197A patent/IL129531A0/xx unknown
- 1997-11-06 NZ NZ335549A patent/NZ335549A/en unknown
- 1997-11-06 DE DE69733695T patent/DE69733695T2/de not_active Expired - Lifetime
- 1997-11-06 ES ES97911353T patent/ES2243986T3/es not_active Expired - Lifetime
- 1997-11-06 JP JP52115098A patent/JP4339406B2/ja not_active Expired - Fee Related
- 1997-11-06 TR TR1999/01000T patent/TR199901000T2/xx unknown
- 1997-11-06 KR KR10-1999-7004079A patent/KR100393234B1/ko not_active Expired - Fee Related
- 1997-11-06 CN CNA2004100055918A patent/CN1524583A/zh active Pending
-
1999
- 1999-05-05 NO NO992196A patent/NO992196L/no unknown
- 1999-05-28 BG BG103444A patent/BG103444A/xx unknown