JP2001502534A5 - - Google Patents

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Publication number
JP2001502534A5
JP2001502534A5 JP1998517538A JP51753898A JP2001502534A5 JP 2001502534 A5 JP2001502534 A5 JP 2001502534A5 JP 1998517538 A JP1998517538 A JP 1998517538A JP 51753898 A JP51753898 A JP 51753898A JP 2001502534 A5 JP2001502534 A5 JP 2001502534A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998517538A
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English (en)
Japanese (ja)
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JP4160121B2 (ja
JP2001502534A (ja
Filing date
Publication date
Priority claimed from US08/710,305 external-priority patent/US5801012A/en
Application filed filed Critical
Publication of JP2001502534A publication Critical patent/JP2001502534A/ja
Publication of JP2001502534A5 publication Critical patent/JP2001502534A5/ja
Application granted granted Critical
Publication of JP4160121B2 publication Critical patent/JP4160121B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP51753898A 1996-09-17 1997-09-17 アンジオスタチン生成のための方法及び組成物 Expired - Fee Related JP4160121B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/710,305 1996-09-17
US08/710,305 US5801012A (en) 1996-09-17 1996-09-17 Methods and compositions for generating angiostatin
PCT/US1997/016539 WO1998015574A1 (en) 1996-09-17 1997-09-17 Methods and compositions for generating angiostatin

Publications (3)

Publication Number Publication Date
JP2001502534A JP2001502534A (ja) 2001-02-27
JP2001502534A5 true JP2001502534A5 (enExample) 2005-05-12
JP4160121B2 JP4160121B2 (ja) 2008-10-01

Family

ID=24853480

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51753898A Expired - Fee Related JP4160121B2 (ja) 1996-09-17 1997-09-17 アンジオスタチン生成のための方法及び組成物

Country Status (9)

Country Link
US (2) US5801012A (enExample)
EP (2) EP1705184A1 (enExample)
JP (1) JP4160121B2 (enExample)
AT (1) ATE329926T1 (enExample)
AU (1) AU4422797A (enExample)
CA (1) CA2265550A1 (enExample)
DE (1) DE69736129T2 (enExample)
ES (1) ES2267151T3 (enExample)
WO (1) WO1998015574A1 (enExample)

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US5945403A (en) * 1997-05-30 1999-08-31 The Children's Medical Center Corporation Angiostatin fragments and method of use
US7297331B2 (en) * 1996-04-03 2007-11-20 The Rogosin Institute Beads containing restricted cancer cells producing material suppressing cancer cell proliferation
WO1999000420A1 (en) * 1997-06-26 1999-01-07 Karolinska Innovations Ab Kringle domains 1-5 of plasminogen, capable of modulating angiogenesis in vivo
JP2002531385A (ja) * 1998-11-25 2002-09-24 ブリストル−マイヤーズ スクイブ カンパニー アンジオスタチンおよびプラスミノゲンのクリングル5領域を含む組成物およびその使用方法
EP1214346A1 (en) 1999-09-15 2002-06-19 Mogam Biotechnology Research Institute A novel angiogenesis inhibitor
AU2001234926A1 (en) * 2000-02-08 2001-08-20 Northwestern University Methods and compositions for generating angiostatin
CA2421251A1 (en) 2000-09-05 2002-03-14 Karolinska Innovations Ab Recombinant endothelial cell growth inhibitors derived from a mammalian plasminogen
US7420036B2 (en) 2000-11-28 2008-09-02 Waisman David M Anti-angiogenic polypeptides
ITMI20011995A1 (it) * 2001-09-26 2003-03-26 Ist Naz Ricerca Sul Cancro Sostanze ad attivita' antinfiammatoria
US7285277B2 (en) * 2002-03-15 2007-10-23 Mogam Biotechnology Research Institute Anticancer agent
CN100384819C (zh) * 2002-07-02 2008-04-30 诺瓦提斯公司 与细胞凋亡蛋白抑制剂结合的smac蛋白的肽抑制剂
AU2003297181A1 (en) * 2002-12-13 2004-07-09 Mediomics, Llc Compositions and methods for inhibiting tumor growth and metastasis
US7141035B2 (en) * 2003-03-28 2006-11-28 Sherwood Services Ag Catheter with occlusion resistant tip
US7090654B2 (en) * 2003-03-28 2006-08-15 Sherwood Services Ag Catheter with occlusion resistant tip
US7776005B2 (en) * 2003-03-28 2010-08-17 Covidien Ag Triple lumen catheter with occlusion resistant tip
US20050281879A1 (en) * 2003-11-14 2005-12-22 Guohua Chen Excipients in drug delivery vehicles
CN1889929B (zh) * 2003-11-14 2013-04-10 阿尔萨公司 药物递送媒介物中的赋形剂
CN101107023B (zh) 2004-11-04 2010-06-09 科维蒂恩股份公司 导管插入装置
US20070027105A1 (en) 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
WO2009100617A1 (zh) * 2008-02-04 2009-08-20 Shanghai First People's Hospital 抑制血管新生的多肽及其应用
EP2445547B1 (en) * 2009-06-26 2017-08-02 Covidien LP Catheterization system
CA2715857A1 (en) 2009-09-30 2011-03-30 Tyco Healthcare Group Lp Medical catheter having a design providing low recirculation and reversibility
US8747343B2 (en) 2011-09-30 2014-06-10 Covidien Lp Hemodialysis catheter with improved side opening design
US9072867B2 (en) 2011-09-30 2015-07-07 Covidien Lp Catheter with external flow channel
US9216163B2 (en) 2013-05-20 2015-12-22 Kyorin Pharmaceutical Co., Ltd. Method of inhibiting angiogenesis
KR20220140711A (ko) 2020-01-13 2022-10-18 듀렉트 코퍼레이션 불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법
EP4277702A1 (en) 2021-01-12 2023-11-22 Durect Corporation Sustained release drug delivery systems and related methods

Family Cites Families (22)

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Publication number Priority date Publication date Assignee Title
DE2431342C3 (de) * 1973-07-27 1978-10-26 Behringwerke Ag, 3550 Marburg Verfahren zur Messung des Plasminogengehaltes durch Bestimmung der Bildung von Fibrin in einer Probe
US4968494A (en) * 1987-03-27 1990-11-06 Merck & Co., Inc. Methods and compositions for thrombolytic therapy
US5135919A (en) 1988-01-19 1992-08-04 Children's Medical Center Corporation Method and a pharmaceutical composition for the inhibition of angiogenesis
US5021404A (en) 1988-04-20 1991-06-04 The Children's Medical Center Corporation Angiostatic collagen modulators
KR0138530B1 (ko) 1988-09-01 1998-05-15 우메모또 요시마사 푸마길롤 유도체
PT93847A (pt) 1989-04-24 1990-11-20 Harvard College Processo para a preparacao de oligossacaridos de baixo peso molecular derivados de heparina ou de sulfato de heparano despolimerizados e de composicoes farmaceuticas que os contem
US5290807A (en) 1989-08-10 1994-03-01 Children's Medical Center Corporation Method for regressing angiogenesis using o-substituted fumagillol derivatives
US5192744A (en) 1990-01-12 1993-03-09 Northwestern University Method of inhibiting angiogenesis of tumors
US5504074A (en) 1993-08-06 1996-04-02 Children's Medical Center Corporation Estrogenic compounds as anti-angiogenic agents
WO1995029242A1 (en) * 1994-04-26 1995-11-02 The Children's Medical Center Corporation Angiostatin and method of use for inhibition of angiogenesis
US5639725A (en) 1994-04-26 1997-06-17 Children's Hospital Medical Center Corp. Angiostatin protein
US5837682A (en) 1996-03-08 1998-11-17 The Children's Medical Center Corporation Angiostatin fragments and method of use
US5945403A (en) 1997-05-30 1999-08-31 The Children's Medical Center Corporation Angiostatin fragments and method of use
US5861372A (en) 1996-02-22 1999-01-19 The Children's Medical Center Corporation Aggregate angiostatin and method of use
MX9708217A (es) 1995-04-26 1997-12-31 Childrens Medical Center Fragmentos de angiostatina y angiostatina agregada y metodos de uso.
AU6264596A (en) 1995-06-07 1996-12-30 Children's Medical Center Corporation Diagnosis, prognosis and monitoring of angiogenesis dependen t diseases
DE19529223A1 (de) * 1995-08-09 1997-02-13 Boehringer Mannheim Gmbh Verwendung von Plasminogenaktivatoren zum lokalen Knochenaufbau
ES2206602T3 (es) 1995-10-23 2004-05-16 The Children's Medical Center Corporation Compuestos y metodos terapeuticos inhibidores de angiogenesis.
US5854221A (en) 1996-12-12 1998-12-29 The Children's Medical Center Corporation Endothelial cell proliferation inhibitor and method of use
WO1997023500A1 (en) 1995-12-13 1997-07-03 The Children's Medical Center Corporation Endothelial cell proliferation inhibitor and method of use
HU224827B1 (hu) 1996-05-03 2006-02-28 Abbott Lab Új antiangiogén peptidek, azokat kódoló polinukleotidok, és eljárások angiogenezis gátlására
WO1999000420A1 (en) 1997-06-26 1999-01-07 Karolinska Innovations Ab Kringle domains 1-5 of plasminogen, capable of modulating angiogenesis in vivo

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