JP2001502534A5 - - Google Patents
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- Publication number
- JP2001502534A5 JP2001502534A5 JP1998517538A JP51753898A JP2001502534A5 JP 2001502534 A5 JP2001502534 A5 JP 2001502534A5 JP 1998517538 A JP1998517538 A JP 1998517538A JP 51753898 A JP51753898 A JP 51753898A JP 2001502534 A5 JP2001502534 A5 JP 2001502534A5
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- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Description
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/710,305 | 1996-09-17 | ||
US08/710,305 US5801012A (en) | 1996-09-17 | 1996-09-17 | Methods and compositions for generating angiostatin |
PCT/US1997/016539 WO1998015574A1 (en) | 1996-09-17 | 1997-09-17 | Methods and compositions for generating angiostatin |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2001502534A JP2001502534A (ja) | 2001-02-27 |
JP2001502534A5 true JP2001502534A5 (ja) | 2005-05-12 |
JP4160121B2 JP4160121B2 (ja) | 2008-10-01 |
Family
ID=24853480
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP51753898A Expired - Fee Related JP4160121B2 (ja) | 1996-09-17 | 1997-09-17 | アンジオスタチン生成のための方法及び組成物 |
Country Status (9)
Country | Link |
---|---|
US (2) | US5801012A (ja) |
EP (2) | EP1705184A1 (ja) |
JP (1) | JP4160121B2 (ja) |
AT (1) | ATE329926T1 (ja) |
AU (1) | AU4422797A (ja) |
CA (1) | CA2265550A1 (ja) |
DE (1) | DE69736129T2 (ja) |
ES (1) | ES2267151T3 (ja) |
WO (1) | WO1998015574A1 (ja) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5945403A (en) * | 1997-05-30 | 1999-08-31 | The Children's Medical Center Corporation | Angiostatin fragments and method of use |
US7297331B2 (en) * | 1996-04-03 | 2007-11-20 | The Rogosin Institute | Beads containing restricted cancer cells producing material suppressing cancer cell proliferation |
AU7951798A (en) * | 1997-06-26 | 1999-01-19 | Karolinska Innovations Ab | Kringle domains 1-5 of plasminogen, capable of modulating angiogenesis in vivo |
AU1731300A (en) * | 1998-11-25 | 2000-06-13 | Bristol-Myers Squibb Company | Compositions comprising angiostatin and kringle 5 region of plasminogen and methods of use thereof |
JP3725473B2 (ja) | 1999-09-15 | 2005-12-14 | モーガン バイオテクノロジー リサーチ インスティテュート | 新規血管形成阻害剤 |
WO2001058921A2 (en) * | 2000-02-08 | 2001-08-16 | Northwestern University | Methods and compositions for generating angiostatin |
JP2004508048A (ja) | 2000-09-05 | 2004-03-18 | カロリンスカ イノベーションズ アクティーエボラーグ | 内皮細胞増殖阻害物質に関する材料と方法 |
AU2002239366A1 (en) | 2000-11-28 | 2002-06-11 | Geetha Kassam | Anti-angiogenic polypeptides |
ITMI20011995A1 (it) * | 2001-09-26 | 2003-03-26 | Ist Naz Ricerca Sul Cancro | Sostanze ad attivita' antinfiammatoria |
US7285277B2 (en) * | 2002-03-15 | 2007-10-23 | Mogam Biotechnology Research Institute | Anticancer agent |
US20060128632A1 (en) * | 2002-07-02 | 2006-06-15 | Sharma Sushil K | Peptide inhibitors of smac protein binding to inhibitor of apoptosis proteins (iap) |
CA2514873C (en) * | 2002-12-13 | 2012-01-03 | David Waisman | Compositions and methods for inhibiting tumor growth and metastasis |
US7776005B2 (en) * | 2003-03-28 | 2010-08-17 | Covidien Ag | Triple lumen catheter with occlusion resistant tip |
US7090654B2 (en) * | 2003-03-28 | 2006-08-15 | Sherwood Services Ag | Catheter with occlusion resistant tip |
US7141035B2 (en) * | 2003-03-28 | 2006-11-28 | Sherwood Services Ag | Catheter with occlusion resistant tip |
US20050281879A1 (en) * | 2003-11-14 | 2005-12-22 | Guohua Chen | Excipients in drug delivery vehicles |
CN1889929B (zh) * | 2003-11-14 | 2013-04-10 | 阿尔萨公司 | 药物递送媒介物中的赋形剂 |
US9913962B2 (en) * | 2004-11-04 | 2018-03-13 | Covidien Ag | Catheter insertion apparatus |
US20070027105A1 (en) | 2005-07-26 | 2007-02-01 | Alza Corporation | Peroxide removal from drug delivery vehicle |
WO2009100617A1 (zh) * | 2008-02-04 | 2009-08-20 | Shanghai First People's Hospital | 抑制血管新生的多肽及其应用 |
EP2445547B1 (en) * | 2009-06-26 | 2017-08-02 | Covidien LP | Catheterization system |
CA2715857A1 (en) | 2009-09-30 | 2011-03-30 | Tyco Healthcare Group Lp | Medical catheter having a design providing low recirculation and reversibility |
US9072867B2 (en) | 2011-09-30 | 2015-07-07 | Covidien Lp | Catheter with external flow channel |
US8747343B2 (en) | 2011-09-30 | 2014-06-10 | Covidien Lp | Hemodialysis catheter with improved side opening design |
US9216163B2 (en) | 2013-05-20 | 2015-12-22 | Kyorin Pharmaceutical Co., Ltd. | Method of inhibiting angiogenesis |
BR112022013784A2 (pt) | 2020-01-13 | 2022-10-11 | Durect Corp | Sistemas de distribuição de fármacos de liberação prolongada com impurezas reduzidas e métodos relacionados |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2431342C3 (de) * | 1973-07-27 | 1978-10-26 | Behringwerke Ag, 3550 Marburg | Verfahren zur Messung des Plasminogengehaltes durch Bestimmung der Bildung von Fibrin in einer Probe |
US4968494A (en) * | 1987-03-27 | 1990-11-06 | Merck & Co., Inc. | Methods and compositions for thrombolytic therapy |
US5135919A (en) | 1988-01-19 | 1992-08-04 | Children's Medical Center Corporation | Method and a pharmaceutical composition for the inhibition of angiogenesis |
US5021404A (en) | 1988-04-20 | 1991-06-04 | The Children's Medical Center Corporation | Angiostatic collagen modulators |
EP0359036B1 (en) | 1988-09-01 | 1997-03-26 | Takeda Chemical Industries, Ltd. | Fumagillol derivatives |
PT93847A (pt) | 1989-04-24 | 1990-11-20 | Harvard College | Processo para a preparacao de oligossacaridos de baixo peso molecular derivados de heparina ou de sulfato de heparano despolimerizados e de composicoes farmaceuticas que os contem |
US5290807A (en) | 1989-08-10 | 1994-03-01 | Children's Medical Center Corporation | Method for regressing angiogenesis using o-substituted fumagillol derivatives |
US5192744A (en) | 1990-01-12 | 1993-03-09 | Northwestern University | Method of inhibiting angiogenesis of tumors |
US5504074A (en) | 1993-08-06 | 1996-04-02 | Children's Medical Center Corporation | Estrogenic compounds as anti-angiogenic agents |
US5945403A (en) | 1997-05-30 | 1999-08-31 | The Children's Medical Center Corporation | Angiostatin fragments and method of use |
AU710612B2 (en) | 1995-12-13 | 1999-09-23 | Abbvie Inc. | Endothelial cell proliferation inhibitor and method of use |
US5837682A (en) | 1996-03-08 | 1998-11-17 | The Children's Medical Center Corporation | Angiostatin fragments and method of use |
JP3880064B2 (ja) * | 1994-04-26 | 2007-02-14 | ザ チルドレンズ メディカル センター コーポレイション | アンジオスタチンおよび血管形成の抑制におけるその使用 |
US5639725A (en) | 1994-04-26 | 1997-06-17 | Children's Hospital Medical Center Corp. | Angiostatin protein |
US5861372A (en) | 1996-02-22 | 1999-01-19 | The Children's Medical Center Corporation | Aggregate angiostatin and method of use |
JP3787157B2 (ja) | 1995-04-26 | 2006-06-21 | ザ チルドレンズ メディカル センター コーポレイション | アンジオスタチンフラグメント、アンジオスタチン凝集体および使用方法 |
WO1996041194A1 (en) | 1995-06-07 | 1996-12-19 | The Children's Medical Center Corporation | Diagnosis, prognosis and monitoring of angiogenesis dependent diseases |
DE19529223A1 (de) * | 1995-08-09 | 1997-02-13 | Boehringer Mannheim Gmbh | Verwendung von Plasminogenaktivatoren zum lokalen Knochenaufbau |
CZ117798A3 (cs) | 1995-10-23 | 1998-08-12 | The Children's Medical Center Corporation | Antiangiogenní kompozice a způsoby léčby |
US5854221A (en) | 1996-12-12 | 1998-12-29 | The Children's Medical Center Corporation | Endothelial cell proliferation inhibitor and method of use |
JP4426650B2 (ja) | 1996-05-03 | 2010-03-03 | アボット・ラボラトリーズ | 新規な抗血管形成ペプチド、それをコードするポリヌクレオチド、および血管形成を阻害する方法 |
AU7951798A (en) | 1997-06-26 | 1999-01-19 | Karolinska Innovations Ab | Kringle domains 1-5 of plasminogen, capable of modulating angiogenesis in vivo |
-
1996
- 1996-09-17 US US08/710,305 patent/US5801012A/en not_active Expired - Fee Related
-
1997
- 1997-09-17 ES ES97942549T patent/ES2267151T3/es not_active Expired - Lifetime
- 1997-09-17 DE DE69736129T patent/DE69736129T2/de not_active Expired - Fee Related
- 1997-09-17 CA CA002265550A patent/CA2265550A1/en not_active Abandoned
- 1997-09-17 EP EP06112574A patent/EP1705184A1/en not_active Withdrawn
- 1997-09-17 AT AT97942549T patent/ATE329926T1/de not_active IP Right Cessation
- 1997-09-17 EP EP97942549A patent/EP0964869B1/en not_active Expired - Lifetime
- 1997-09-17 JP JP51753898A patent/JP4160121B2/ja not_active Expired - Fee Related
- 1997-09-17 WO PCT/US1997/016539 patent/WO1998015574A1/en active IP Right Grant
- 1997-09-18 AU AU44227/97A patent/AU4422797A/en not_active Abandoned
- 1997-12-16 US US08/991,761 patent/US6576609B1/en not_active Expired - Fee Related