|
AU561343B2
(en)
|
1981-10-19 |
1987-05-07 |
Genentech Inc. |
Human immune interferon by recombinant dna
|
|
US4603112A
(en)
|
1981-12-24 |
1986-07-29 |
Health Research, Incorporated |
Modified vaccinia virus
|
|
US4769330A
(en)
|
1981-12-24 |
1988-09-06 |
Health Research, Incorporated |
Modified vaccinia virus and methods for making and using the same
|
|
EP0091539B2
(en)
|
1982-03-31 |
1996-11-27 |
Ajinomoto Co., Inc. |
Gene coding for interleukin-2 polypeptide, recombinant DNA carrying said gene, cell lines possessing the recombinant DNA,and method for producing interleukin-2 using said cells
|
|
JPS5936698A
(ja)
|
1982-08-20 |
1984-02-28 |
Science & Tech Agency |
B型肝炎ウイルス遺伝子を組込んだ組換えdnaおよび形質転換動物細胞
|
|
US4966843A
(en)
|
1982-11-01 |
1990-10-30 |
Cetus Corporation |
Expression of interferon genes in Chinese hamster ovary cells
|
|
US4892743A
(en)
|
1983-12-21 |
1990-01-09 |
Schering Corporation |
Novel hybrid interferon species
|
|
EP0165942A1
(en)
|
1983-12-23 |
1986-01-02 |
Monash University |
PRODUCTION OF HUMAN INTERFERON-$g(a)
|
|
US4696898A
(en)
|
1984-01-16 |
1987-09-29 |
Integrated Genetics, Inc. |
Vector encoding hepatitis B surface antigen
|
|
US4599231A
(en)
|
1984-03-09 |
1986-07-08 |
Scripps Clinic And Research Foundation |
Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
|
|
WO1985004103A1
(en)
|
1984-03-09 |
1985-09-26 |
Scripps Clinic And Research Foundation |
Synthetic hepatitis b virus vaccine including both t cell anc b cell determinants
|
|
US4599230A
(en)
|
1984-03-09 |
1986-07-08 |
Scripps Clinic And Research Foundation |
Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
|
|
AU594014B2
(en)
|
1984-03-21 |
1990-03-01 |
Research Corporation Technologies, Inc. |
Recombinant DNA molecules
|
|
US5288641A
(en)
|
1984-06-04 |
1994-02-22 |
Arch Development Corporation |
Herpes Simplex virus as a vector
|
|
US4683136A
(en)
|
1985-03-06 |
1987-07-28 |
Scripps Clinic And Research Foundation |
Proteinaceous antigens with conformation-independent and conformation-dependent determinants
|
|
US4683202A
(en)
|
1985-03-28 |
1987-07-28 |
Cetus Corporation |
Process for amplifying nucleic acid sequences
|
|
US4683195A
(en)
|
1986-01-30 |
1987-07-28 |
Cetus Corporation |
Process for amplifying, detecting, and/or-cloning nucleic acid sequences
|
|
GB8508845D0
(en)
|
1985-04-04 |
1985-05-09 |
Hoffmann La Roche |
Vaccinia dna
|
|
US4810643A
(en)
|
1985-08-23 |
1989-03-07 |
Kirin- Amgen Inc. |
Production of pluripotent granulocyte colony-stimulating factor
|
|
JPS63500636A
(ja)
|
1985-08-23 |
1988-03-10 |
麒麟麦酒株式会社 |
多分化能性顆粒球コロニー刺激因子をコードするdna
|
|
US4777127A
(en)
|
1985-09-30 |
1988-10-11 |
Labsystems Oy |
Human retrovirus-related products and methods of diagnosing and treating conditions associated with said retrovirus
|
|
US5017691A
(en)
|
1986-07-03 |
1991-05-21 |
Schering Corporation |
Mammalian interleukin-4
|
|
US5091309A
(en)
|
1986-01-16 |
1992-02-25 |
Washington University |
Sindbis virus vectors
|
|
US4800159A
(en)
|
1986-02-07 |
1989-01-24 |
Cetus Corporation |
Process for amplifying, detecting, and/or cloning nucleic acid sequences
|
|
JPS62236493A
(ja)
|
1986-04-08 |
1987-10-16 |
Green Cross Corp:The |
HBウイルスのPre S領域を含むHBsAgの製造方法
|
|
AU617292B2
(en)
|
1986-06-20 |
1991-11-28 |
Scripps Clinic And Research Foundation |
T and b cell epitopes of the pre-s region of hepatitis b virus surface antigen
|
|
US4818527A
(en)
|
1986-12-09 |
1989-04-04 |
Scripps Clinic And Research Foundation |
T cell epitopes of the hepatitis B virus nucleocapsid protein
|
|
US4882145A
(en)
|
1986-12-09 |
1989-11-21 |
Scripps Clinic And Research Foundation |
T cell epitopes of the hepatitis B virus nucleocapsid protein
|
|
US5143726A
(en)
|
1986-12-09 |
1992-09-01 |
The Scripps Research Institute |
T cell epitopes of the hepatitis B virus nucleocapsid protein
|
|
ZA88488B
(en)
|
1987-01-30 |
1988-10-26 |
Smith Kline Rit |
Hepatitis b virus surface antigens and hybrid antigens containing them
|
|
GB8702816D0
(en)
|
1987-02-07 |
1987-03-11 |
Al Sumidaie A M K |
Obtaining retrovirus-containing fraction
|
|
US5219740A
(en)
|
1987-02-13 |
1993-06-15 |
Fred Hutchinson Cancer Research Center |
Retroviral gene transfer into diploid fibroblasts for gene therapy
|
|
US5166320A
(en)
|
1987-04-22 |
1992-11-24 |
University Of Connecticut |
Carrier system and method for the introduction of genes into mammalian cells
|
|
WO1988010301A1
(en)
|
1987-06-22 |
1988-12-29 |
Mccormick And Jones Engineering Ltd. |
Hepatitis b surface antigen vaccine
|
|
US5532143A
(en)
|
1987-08-07 |
1996-07-02 |
The Medical Research Council |
Isolated DNA molecules for intergration site independent gene expression in mammalian host cells
|
|
WO1989001973A2
(en)
|
1987-09-02 |
1989-03-09 |
Applied Biotechnology, Inc. |
Recombinant pox virus for immunization against tumor-associated antigens
|
|
US5591624A
(en)
|
1988-03-21 |
1997-01-07 |
Chiron Viagene, Inc. |
Retroviral packaging cell lines
|
|
US5662896A
(en)
|
1988-03-21 |
1997-09-02 |
Chiron Viagene, Inc. |
Compositions and methods for cancer immunotherapy
|
|
US5716826A
(en)
|
1988-03-21 |
1998-02-10 |
Chiron Viagene, Inc. |
Recombinant retroviruses
|
|
AP129A
(en)
|
1988-06-03 |
1991-04-17 |
Smithkline Biologicals S A |
Expression of retrovirus gag protein eukaryotic cells
|
|
WO1990006370A1
(en)
|
1988-12-01 |
1990-06-14 |
The Trustees Of The University Of North Carolina |
Synthetic interleukin-6
|
|
US5217879A
(en)
|
1989-01-12 |
1993-06-08 |
Washington University |
Infectious Sindbis virus vectors
|
|
WO1990007936A1
(en)
|
1989-01-23 |
1990-07-26 |
Chiron Corporation |
Recombinant therapies for infection and hyperproliferative disorders
|
|
US5703055A
(en)
|
1989-03-21 |
1997-12-30 |
Wisconsin Alumni Research Foundation |
Generation of antibodies through lipid mediated DNA delivery
|
|
DE69034078T2
(de)
|
1989-03-21 |
2004-04-01 |
Vical, Inc., San Diego |
Expression von exogenen Polynukleotidsequenzen in Wirbeltieren
|
|
GB8914543D0
(en)
|
1989-06-23 |
1989-08-09 |
Parker David |
Chemical compounds
|
|
EP1645635A3
(en)
|
1989-08-18 |
2010-07-07 |
Oxford Biomedica (UK) Limited |
Replication defective recombinant retroviruses expressing a palliative
|
|
US5166057A
(en)
|
1989-08-28 |
1992-11-24 |
The Mount Sinai School Of Medicine Of The City University Of New York |
Recombinant negative strand rna virus expression-systems
|
|
GB8919607D0
(en)
|
1989-08-30 |
1989-10-11 |
Wellcome Found |
Novel entities for cancer therapy
|
|
AU7007491A
(en)
|
1990-02-02 |
1991-08-08 |
Schweiz. Serum- & Impfinstitut Bern |
Cdna corresponding to the genome of negative-strand rna viruses, and process for the production of infectious negative-strand rna viruses
|
|
PT97632A
(pt)
|
1990-05-11 |
1992-03-31 |
Scripps Clinic Res |
Processo de obtencao de polipeptidos relacionados com a proteina do antigenio de superficie do virus da hepatite b e de vacinas que os contem
|
|
JPH06500923A
(ja)
|
1990-09-21 |
1994-01-27 |
カイロン コーポレイション |
パッケージング細胞
|
|
US5753258A
(en)
|
1990-10-19 |
1998-05-19 |
University Of Florida |
Artificial viral envelopes
|
|
CA2094608A1
(en)
|
1990-10-22 |
1992-04-23 |
John D. Taylor |
Dna construct for providing rna therapy
|
|
US5462734A
(en)
|
1990-11-02 |
1995-10-31 |
Wisconsin Alumni Research Foundation |
Bovine herpesvirus vaccine and method of using same
|
|
EP0563323A4
(en)
*
|
1990-12-19 |
1996-02-28 |
Epitope Inc |
Hiv reverse transcriptase vaccine
|
|
US5843463A
(en)
*
|
1990-12-21 |
1998-12-01 |
Antexbiologics, Inc. |
Adhesin-oligosaccharide conjugate vaccine for Haemophilus influenzae
|
|
US5863542A
(en)
|
1991-03-07 |
1999-01-26 |
Virogenetics Corporation |
Recombinant attenuated ALVAC canaryopox virus containing heterologous HIV or SIV inserts
|
|
US5612201A
(en)
|
1991-05-23 |
1997-03-18 |
Ludwig Institute For Cancer Research |
Isolated nucleic acid molecules useful in determining expression of a tumor rejection antigen precursor
|
|
US5203975A
(en)
|
1991-10-29 |
1993-04-20 |
E. I. Du Pont De Nemours And Company |
Process for cathodic electrodeposition of a clear coating over a conductive paint layer
|
|
WO1993010218A1
(en)
|
1991-11-14 |
1993-05-27 |
The United States Government As Represented By The Secretary Of The Department Of Health And Human Services |
Vectors including foreign genes and negative selective markers
|
|
ATE152915T1
(de)
|
1991-11-29 |
1997-05-15 |
Viagene Inc |
Immuntherapeutische vektorkonstrukte gegen krebs
|
|
GB9125623D0
(en)
|
1991-12-02 |
1992-01-29 |
Dynal As |
Cell modification
|
|
EP0650370A4
(en)
|
1992-06-08 |
1995-11-22 |
Univ California |
METHODS AND COMPOSITIONS TARGETED ON SPECIFIC TISSUES.
|
|
WO1993025698A1
(en)
|
1992-06-10 |
1993-12-23 |
The United States Government As Represented By The |
Vector particles resistant to inactivation by human serum
|
|
GB2269175A
(en)
|
1992-07-31 |
1994-02-02 |
Imperial College |
Retroviral vectors
|
|
WO1994017813A1
(en)
|
1993-02-08 |
1994-08-18 |
Paravax, Inc. |
Defective sindbis virus vectors that express toxoplasma gondii p30 antigens
|
|
CA2161095A1
(en)
*
|
1993-04-20 |
1994-10-27 |
Solis Therapeutics, Inc. |
Methods and materials for treatment of individuals infected with intracellular infectious agents
|
|
EP0984068B1
(en)
*
|
1993-04-27 |
2012-03-28 |
Innogenetics N.V. |
Sequences of hepatitis c virus genotypes and their use as therapeutic and diagnostic agents
|
|
US5447859A
(en)
|
1993-07-16 |
1995-09-05 |
Viagene |
Method for the purification or removal of retroviruses using sulfated cellulose
|
|
US5755602A
(en)
*
|
1993-08-04 |
1998-05-26 |
Klukowski; Slawomir |
Nautical propulsion device
|
|
DK0638316T3
(da)
*
|
1993-08-11 |
2003-09-22 |
Wyeth Corp |
Rekombinante adenovirusvacciner
|
|
US5679647A
(en)
|
1993-08-26 |
1997-10-21 |
The Regents Of The University Of California |
Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides
|
|
US6015686A
(en)
|
1993-09-15 |
2000-01-18 |
Chiron Viagene, Inc. |
Eukaryotic layered vector initiation systems
|
|
CA2158937C
(en)
*
|
1993-09-15 |
2006-01-03 |
Thomas W. Dubensky, Jr. |
Recombinant alphavirus vectors
|
|
KR960703172A
(ko)
|
1993-11-18 |
1996-06-19 |
스티븐 제이. 멘토 |
조건적으로 치사적인 유전자를 활용하기 위한 조성물 및 방법(Compositions and methods for utilizing conditionally lethal genes)
|
|
DE69535125T2
(de)
*
|
1994-04-29 |
2007-08-30 |
Pharmacia & Upjohn Co. Llc, Kalamazoo |
Impfstoff gegen felines immunodefizienz-virus
|
|
US5814617A
(en)
|
1994-10-07 |
1998-09-29 |
The United States Of America As Represented By The Secretary Of The Navy |
Protective 17 KDA malaria hepatic and erythrocytic stage immunogen and gene
|
|
US5736524A
(en)
|
1994-11-14 |
1998-04-07 |
Merck & Co.,. Inc. |
Polynucleotide tuberculosis vaccine
|
|
EP0800403A2
(en)
*
|
1994-12-30 |
1997-10-15 |
Chiron Corporation |
Non-traumatic administration of gene delivery vehicles
|
|
US5681746A
(en)
|
1994-12-30 |
1997-10-28 |
Chiron Viagene, Inc. |
Retroviral delivery of full length factor VIII
|
|
EP0802801A2
(en)
*
|
1994-12-30 |
1997-10-29 |
Chiron Corporation |
Methods and compositions for treatment of solid tumors in vivo
|
|
IL117483A
(en)
|
1995-03-17 |
2008-03-20 |
Bernard Brodeur |
MENINGITIDIS NEISSERIA shell protein is resistant to proteinase K.
|
|
US6689757B1
(en)
*
|
1996-02-12 |
2004-02-10 |
M.L. Laboratories Plc |
Methods for vaccination and vaccines therefor
|
|
WO1997044446A1
(en)
|
1996-05-24 |
1997-11-27 |
University Of Maryland At Baltimore |
Dna vaccines for eliciting a mucosal immune response
|
|
SE9602280D0
(sv)
|
1996-06-10 |
1996-06-10 |
Pharmatrix Ab |
Immunstimulerande lipidformulering
|
|
WO1998012332A1
(en)
*
|
1996-09-17 |
1998-03-26 |
Chiron Corporation |
Compositions and methods for treating intracellular diseases
|
|
US6261570B1
(en)
|
1997-05-20 |
2001-07-17 |
The United States Of America As Represented By The Secretary Of The Army |
Live attenuated virus vaccines for western equine encephalitis virus, eastern equine encephalitis virus, and venezuelan equine encephalitis virus IE and IIIA variants
|
|
DE69841807D1
(de)
|
1997-11-06 |
2010-09-16 |
Novartis Vaccines & Diagnostic |
Neisseriale antigene
|
|
DK1042001T3
(da)
|
1997-12-16 |
2002-07-08 |
Chiron Corp |
Anvendelse af mikropartikler kombineret med submikron-(olie-i-vand)-emulsioner
|
|
DE69941567D1
(de)
|
1998-01-14 |
2009-12-03 |
Novartis Vaccines & Diagnostic |
Antigene aus neisseria meningitidis
|
|
DE69937419T2
(de)
|
1998-05-01 |
2008-07-24 |
Novartis Vaccines and Diagnostics, Inc., Emeryville |
Neisseria Meningitidis Antigene und Zusammenstellungen
|
|
AU761495B2
(en)
|
1998-05-29 |
2003-06-05 |
Chiron Corporation |
Combination meningitidis B/C vaccines
|
|
US6210663B1
(en)
|
1998-08-20 |
2001-04-03 |
The Wistar Institute Of Anatomy And Biology |
Methods of augmenting mucosal immunity through systemic priming and mucosal boosting
|
|
MXPA01003557A
(es)
|
1998-10-09 |
2004-04-05 |
Chiron Corp |
Secuencias genomicas de neisseria y metodos para su uso.
|
|
EP2206785A1
(en)
|
1998-12-31 |
2010-07-14 |
Novartis Vaccines and Diagnostics, Inc. |
Improved expression of HIV polypeptides and production of virus-like particles
|
|
DE60021523T2
(de)
|
1999-01-28 |
2006-06-22 |
Stichting Biomedical Primate Research Center |
Zusammensetzung und verfahren zur immunisierung gegen ein oder mehrere antigene mittels verschiedener rekombinanter vektoren
|
|
PT1154790E
(pt)
|
1999-02-26 |
2005-03-31 |
Chiron Srl |
Reforco da actividade bactericida de antigenios contra a neisseria com oligonucleotidos contendo motivos cg
|
|
BR0010361A
(pt)
|
1999-04-30 |
2003-06-10 |
Chiron Corp |
Seq ências genÈmicas de neisseria e uso destas
|
|
US7368261B1
(en)
|
1999-04-30 |
2008-05-06 |
Novartis Vaccines And Diagnostics Srl |
Conserved Neisserial antigens
|
|
GB9911683D0
(en)
|
1999-05-19 |
1999-07-21 |
Chiron Spa |
Antigenic peptides
|
|
EP2270174A1
(en)
|
1999-05-19 |
2011-01-05 |
Novartis Vaccines and Diagnostics S.r.l. |
Combination neisserial compositions
|
|
GB9916529D0
(en)
|
1999-07-14 |
1999-09-15 |
Chiron Spa |
Antigenic peptides
|
|
GB9928196D0
(en)
|
1999-11-29 |
2000-01-26 |
Chiron Spa |
Combinations of B, C and other antigens
|
|
CA2390344C
(en)
|
1999-11-29 |
2014-08-26 |
Chiron Spa |
85kda neisserial antigen
|
|
EP2275129A3
(en)
|
2000-01-17 |
2013-11-06 |
Novartis Vaccines and Diagnostics S.r.l. |
Outer membrane vesicle (OMV) vaccine comprising N. meningitidis serogroup B outer membrane proteins
|
|
PT1790660E
(pt)
|
2000-02-28 |
2012-09-17 |
Novartis Vaccines & Diagnostic |
Expressão heteróloga de proteínas de neisseria
|
|
WO2001081609A2
(en)
|
2000-03-22 |
2001-11-01 |
Chiron Corporation |
Compositions and methods for generating an immune response utilizing alphavirus-based vector systems
|
|
GB0029919D0
(en)
|
2000-12-07 |
2001-01-24 |
Chiron Spa |
Helicobacter pylori prime & boost vaccination
|
|
US20030021766A1
(en)
|
2001-01-12 |
2003-01-30 |
Michael Vajdy |
Nucleic acid mucosal immunization
|
|
BRPI0713951B8
(pt)
|
2006-06-30 |
2021-05-25 |
Novartis Ag |
derivados de quinazolina, e composição farmacêutica
|