|
KR100361933B1
(ko)
|
1993-09-08 |
2003-02-14 |
라 졸라 파마슈티칼 컴파니 |
화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트
|
|
US5965566A
(en)
*
|
1993-10-20 |
1999-10-12 |
Enzon, Inc. |
High molecular weight polymer-based prodrugs
|
|
US6096336A
(en)
*
|
1996-01-30 |
2000-08-01 |
The Stehlin Foundation For Cancer Research |
Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs
|
|
PL189698B1
(pl)
*
|
1996-03-12 |
2005-09-30 |
Pg Txl Co |
Kompozycja farmaceutyczna zawierająca lek przeciwnowotworowy i jej zastosowania
|
|
US6214966B1
(en)
|
1996-09-26 |
2001-04-10 |
Shearwater Corporation |
Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution
|
|
US20050158273A1
(en)
*
|
1997-09-25 |
2005-07-21 |
Harris J. M. |
Soluble, degradable polyethylene glycol) derivatives for controllable release of bound molecules into solution
|
|
US6011042A
(en)
*
|
1997-10-10 |
2000-01-04 |
Enzon, Inc. |
Acyl polymeric derivatives of aromatic hydroxyl-containing compounds
|
|
US6111107A
(en)
*
|
1997-11-20 |
2000-08-29 |
Enzon, Inc. |
High yield method for stereoselective acylation of tertiary alcohols
|
|
WO1999030727A1
(en)
|
1997-12-17 |
1999-06-24 |
Enzon, Inc. |
Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents
|
|
US6180095B1
(en)
*
|
1997-12-17 |
2001-01-30 |
Enzon, Inc. |
Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents
|
|
ES2211033T3
(es)
*
|
1998-01-07 |
2004-07-01 |
Debio Recherche Pharmaceutique S.A. |
Acrilatos de polietilenglicol heterobifuncionales degradables y geles y conjugados derivados de dichos acrilatos.
|
|
US6153655A
(en)
*
|
1998-04-17 |
2000-11-28 |
Enzon, Inc. |
Terminally-branched polymeric linkers and polymeric conjugates containing the same
|
|
US7953788B2
(en)
*
|
2001-09-29 |
2011-05-31 |
Siebel Systems, Inc. |
System and method for queuing data for an application server
|
|
PT1075282E
(pt)
*
|
1998-04-28 |
2005-09-30 |
Applied Research Systems |
Conjugados analogos de peg-lhrh
|
|
CA2376057A1
(en)
*
|
1999-06-08 |
2000-12-14 |
La Jolla Pharmaceutical Company |
Valency platform molecules comprising aminooxy groups
|
|
WO2001005819A1
(en)
*
|
1999-07-15 |
2001-01-25 |
Kuhnil Pharm. Co., Ltd. |
Novel water soluble-cyclosporine conjugated compounds
|
|
US6352996B1
(en)
|
1999-08-03 |
2002-03-05 |
The Stehlin Foundation For Cancer Research |
Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs
|
|
US6228855B1
(en)
|
1999-08-03 |
2001-05-08 |
The Stehlin Foundation For Cancer Research |
Aromatic esters of camptothecins and methods to treat cancers
|
|
US6713454B1
(en)
|
1999-09-13 |
2004-03-30 |
Nobex Corporation |
Prodrugs of etoposide and etoposide analogs
|
|
US6541508B2
(en)
|
1999-09-13 |
2003-04-01 |
Nobex Corporation |
Taxane prodrugs
|
|
US6380405B1
(en)
*
|
1999-09-13 |
2002-04-30 |
Nobex Corporation |
Taxane prodrugs
|
|
US6376470B1
(en)
*
|
1999-09-23 |
2002-04-23 |
Enzon, Inc. |
Polymer conjugates of ara-C and ara-C derivatives
|
|
JP4776843B2
(ja)
|
1999-10-01 |
2011-09-21 |
イムノゲン インコーポレーティッド |
免疫複合体及び化学療法剤を用いる癌治療用組成物及び方法
|
|
CA2394980C
(en)
*
|
1999-12-22 |
2008-05-13 |
Shearwater Corporation |
Sterically hindered derivatives of water soluble polymers
|
|
WO2001062299A2
(en)
|
2000-02-28 |
2001-08-30 |
Shearwater Corporation |
Water-soluble polymer conjugates of artelinic acid
|
|
CA2414076A1
(en)
|
2000-06-08 |
2001-12-13 |
La Jolla Pharmaceutical Company |
Multivalent platform molecules comprising high molecular weight polyethylene oxide
|
|
MXPA03000310A
(es)
*
|
2000-07-12 |
2004-12-13 |
Gryphon Therapeutics Inc |
Quimiocinas sinteticas bioactivas, modificadas con polimeros y metodos para su elaboracion y uso.
|
|
US7118737B2
(en)
*
|
2000-09-08 |
2006-10-10 |
Amylin Pharmaceuticals, Inc. |
Polymer-modified synthetic proteins
|
|
US20030191291A1
(en)
*
|
2000-09-08 |
2003-10-09 |
Kochendoerfer Gerd G. |
Synthetic erythropoiesis stimulating proteins
|
|
US6436386B1
(en)
|
2000-11-14 |
2002-08-20 |
Shearwater Corporation |
Hydroxyapatite-targeting poly (ethylene glycol) and related polymers
|
|
US7829074B2
(en)
*
|
2001-10-18 |
2010-11-09 |
Nektar Therapeutics |
Hydroxypatite-targeting poly(ethylene glycol) and related polymers
|
|
ATE378071T1
(de)
*
|
2001-02-20 |
2007-11-15 |
Enzon Inc |
Endgruppenverzweigte polymere verbindungen und diese enthaltende polymere konjugate
|
|
EP1362053B1
(en)
*
|
2001-02-20 |
2007-11-14 |
Enzon, Inc. |
Terminally-branched polymeric linkers and polymeric conjugates containing the same
|
|
US20040077835A1
(en)
*
|
2001-07-12 |
2004-04-22 |
Robin Offord |
Chemokine receptor modulators, production and use
|
|
AU2002363334A1
(en)
*
|
2001-11-09 |
2003-05-19 |
Enzon, Inc. |
Polymeric thiol-linked prodrugs
|
|
GB0202906D0
(en)
*
|
2002-02-07 |
2002-03-27 |
Univ London |
Prevention of myocardial damage
|
|
DE10209821A1
(de)
|
2002-03-06 |
2003-09-25 |
Biotechnologie Ges Mittelhesse |
Kopplung von Proteinen an ein modifiziertes Polysaccharid
|
|
DE10209822A1
(de)
*
|
2002-03-06 |
2003-09-25 |
Biotechnologie Ges Mittelhesse |
Kopplung niedermolekularer Substanzen an ein modifiziertes Polysaccharid
|
|
DE60315145T2
(de)
*
|
2002-03-13 |
2008-04-30 |
Beijing Jiankai Technology Co., Ltd. |
Hydrophiles polymerderivat mit y-verzweigung und herstellungsverfahren dafür; obige verbindung enthaltender medizinischer verbundwerkstoff
|
|
WO2003084926A2
(en)
*
|
2002-04-04 |
2003-10-16 |
Enzon, Inc. |
Polymeric acyl derivatives of indoles
|
|
CN100393724C
(zh)
*
|
2002-07-12 |
2008-06-11 |
中国医学科学院药物研究所 |
20-位酯化的喜树碱衍生物及其制法和其药物组合物与用途
|
|
JP4764630B2
(ja)
|
2002-09-09 |
2011-09-07 |
ネクター セラピューティックス |
水溶性ポリマーアルカナール
|
|
US7569214B2
(en)
|
2002-09-09 |
2009-08-04 |
Nektar Therapeutics Al, Corporation |
Method for preparing water-soluble polymer derivatives bearing a terminal carboxylic acid
|
|
MXPA05002594A
(es)
*
|
2002-09-11 |
2005-05-27 |
Fresenius Kabi Gmbh |
Derivados de polipeptidos con hidroxialquilalmidon, especialmente derivados de eritropoyetina con hidroxialquilalmidon.
|
|
US8129330B2
(en)
*
|
2002-09-30 |
2012-03-06 |
Mountain View Pharmaceuticals, Inc. |
Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
|
|
US20040062748A1
(en)
*
|
2002-09-30 |
2004-04-01 |
Mountain View Pharmaceuticals, Inc. |
Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
|
|
CA2502870C
(en)
|
2002-10-31 |
2011-07-26 |
Nippon Kayaku Kabushiki Kaisha |
High-molecular weight derivatives of camptothecins
|
|
US8034900B2
(en)
*
|
2002-12-30 |
2011-10-11 |
Amylin Pharmaceuticals, Inc. |
Water-soluble thioester and selenoester compounds and methods for making and using the same
|
|
CA2518265A1
(en)
*
|
2003-03-17 |
2004-09-30 |
Albany Molecular Research, Inc. |
Novel cyclosporins
|
|
PT2644206T
(pt)
*
|
2003-05-23 |
2019-07-10 |
Nektar Therapeutics |
Derivados de peg contendo duas cadeias de peg
|
|
US7947261B2
(en)
|
2003-05-23 |
2011-05-24 |
Nektar Therapeutics |
Conjugates formed from polymer derivatives having particular atom arrangements
|
|
US7342114B2
(en)
*
|
2003-07-01 |
2008-03-11 |
California Pacific Medical Center |
Podophyllotoxin derivatives
|
|
WO2005014655A2
(en)
*
|
2003-08-08 |
2005-02-17 |
Fresenius Kabi Deutschland Gmbh |
Conjugates of hydroxyalkyl starch and a protein
|
|
PL1660134T3
(pl)
*
|
2003-08-08 |
2011-05-31 |
Fresenius Kabi Deutschland Gmbh |
Koniugaty hydroksyalkiloskrobi i G-CSF
|
|
US8394365B2
(en)
|
2003-09-17 |
2013-03-12 |
Nektar Therapeutics |
Multi-arm polymer prodrugs
|
|
CN1852740B
(zh)
*
|
2003-09-17 |
2011-05-11 |
耐科塔医药公司 |
多支链聚合物的药物前体
|
|
WO2005067644A2
(en)
*
|
2004-01-07 |
2005-07-28 |
Ambit Biosciences Corporation |
Conjugated small molecules
|
|
EP1756173B1
(en)
*
|
2004-01-21 |
2019-04-03 |
Nektar Therapeutics |
Method of preparing propionic acid-terminated polymers
|
|
EP2336192A1
(en)
|
2004-03-11 |
2011-06-22 |
Fresenius Kabi Deutschland GmbH |
Conjugates of hydroxyalkyl starch and a protein, prepared by reductive amination
|
|
EP2279752A3
(en)
*
|
2004-03-11 |
2011-08-24 |
Fresenius Kabi Deutschland GmbH |
Conjugates of hydroxyalkyl starch and a protein, prepared by native chemical ligation
|
|
US7910593B2
(en)
*
|
2004-04-09 |
2011-03-22 |
Chugai Seiyaku Kabushiki Kaisha |
Water-soluble prodrugs
|
|
WO2006020719A2
(en)
|
2004-08-11 |
2006-02-23 |
Arqule, Inc. |
Aminoacid conjugates of beta - lapachone for tumor targeting
|
|
US8614228B2
(en)
|
2004-08-11 |
2013-12-24 |
Arqule, Inc. |
Quinone prodrug compositions and methods of use
|
|
CN101023119B
(zh)
|
2004-09-22 |
2010-05-05 |
日本化药株式会社 |
新型嵌段共聚物,胶束制剂以及含胶束制剂为活性组分的抗癌剂
|
|
US7378391B2
(en)
*
|
2004-09-29 |
2008-05-27 |
Amr Technology, Inc. |
Cyclosporin alkyne analogues and their pharmaceutical uses
|
|
JP2008514702A
(ja)
*
|
2004-09-29 |
2008-05-08 |
エーエムアール テクノロジー インコーポレイテッド |
新規シクロスポリン類似体およびそれらの薬学的使用
|
|
WO2006041631A2
(en)
*
|
2004-10-06 |
2006-04-20 |
Amr Technology, Inc. |
Novel cyclosporin alkynes and their utility as pharmaceutical agents
|
|
US7662781B2
(en)
|
2005-01-31 |
2010-02-16 |
Eci, Inc. |
Immunopotentiating agent
|
|
JP2008532966A
(ja)
*
|
2005-03-11 |
2008-08-21 |
フレゼニウス・カビ・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング |
不活性出発物質からの生理活性糖タンパク質の生成
|
|
WO2006097682A1
(en)
*
|
2005-03-18 |
2006-09-21 |
Ucl Business Plc |
Mechano growth factor peptides and their use
|
|
EP1868652A2
(en)
|
2005-04-05 |
2007-12-26 |
Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. |
Method for shielding functional sites or epitopes on proteins
|
|
TW200744603A
(en)
|
2005-08-22 |
2007-12-16 |
Chugai Pharmaceutical Co Ltd |
Novel anticancer concomitant drug
|
|
EP1762250A1
(en)
*
|
2005-09-12 |
2007-03-14 |
Fresenius Kabi Deutschland GmbH |
Conjugates of hydroxyalkyl starch and an active substance, prepared by chemical ligation via thiazolidine
|
|
WO2007075534A2
(en)
|
2005-12-16 |
2007-07-05 |
Nektar Therapeutics Al, Corporation |
Polymer conjugates of glp-1
|
|
US7462627B2
(en)
*
|
2006-02-09 |
2008-12-09 |
Enzon Pharmaceuticals, Inc. |
Multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin for treatment of breast, colorectal, pancreatic, ovarian and lung cancers
|
|
US7671067B2
(en)
*
|
2006-02-09 |
2010-03-02 |
Enzon Pharmaceuticals, Inc. |
Treatment of non-hodgkin's lymphomas with multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamtothecin
|
|
EP2319542B1
(en)
|
2006-02-21 |
2018-03-21 |
Nektar Therapeutics |
Segmented degradable polymers and conjugates made therefrom
|
|
KR20080106254A
(ko)
|
2006-03-28 |
2008-12-04 |
니폰 가야꾸 가부시끼가이샤 |
탁산류의 고분자 결합체
|
|
US7696165B2
(en)
*
|
2006-03-28 |
2010-04-13 |
Albany Molecular Research, Inc. |
Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
|
|
US7696166B2
(en)
*
|
2006-03-28 |
2010-04-13 |
Albany Molecular Research, Inc. |
Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
|
|
CA2653748A1
(en)
|
2006-05-02 |
2007-11-15 |
Allozyne, Inc. |
Non-natural amino acid substituted polypeptides
|
|
US20080096819A1
(en)
*
|
2006-05-02 |
2008-04-24 |
Allozyne, Inc. |
Amino acid substituted molecules
|
|
CA2652656A1
(en)
|
2006-05-18 |
2007-11-29 |
Nippon Kayaku Kabushiki Kaisha |
High-molecular weight conjugate of podophyllotoxins
|
|
EP2102144A4
(en)
|
2006-09-13 |
2011-03-23 |
Univ Rutgers |
ACTIVE SUBSTANCES AND THEIR OLIGOMERS AND POLYMERS
|
|
CA2662962A1
(en)
*
|
2006-09-15 |
2008-03-20 |
Enzon Pharmaceuticals, Inc. |
Polyalkylene oxides having hindered ester-based biodegradable linkers
|
|
US8110559B2
(en)
*
|
2006-09-15 |
2012-02-07 |
Enzon Pharmaceuticals, Inc. |
Hindered ester-based biodegradable linkers for oligonucleotide delivery
|
|
WO2008034120A2
(en)
*
|
2006-09-15 |
2008-03-20 |
Enzon Pharmaceuticals, Inc. |
Lysine-based polymeric linkers
|
|
US7985783B2
(en)
|
2006-09-21 |
2011-07-26 |
The Regents Of The University Of California |
Aldehyde tags, uses thereof in site-specific protein modification
|
|
CA2664852A1
(en)
*
|
2006-10-03 |
2008-04-10 |
Nippon Kayaku Kabushiki Kaisha |
High-molecular weight conjugate of resorcinol derivatives
|
|
EP2080779B1
(en)
|
2006-11-06 |
2016-05-18 |
Nippon Kayaku Kabushiki Kaisha |
Polymeric derivative of nucleic acid metabolic antagonist
|
|
EP2090607B1
(en)
|
2006-11-08 |
2015-05-20 |
Nippon Kayaku Kabushiki Kaisha |
Polymeric derivative of nucleic acid metabolic antagonist
|
|
MX2009005780A
(es)
|
2006-11-30 |
2009-06-10 |
Nektar Therapeutics Al Corp |
Metodo para preparar un conjugado de polimeros.
|
|
MX2009008549A
(es)
*
|
2007-02-09 |
2009-08-18 |
Enzon Pharmaceuticals Inc |
Tratamiento de canceres resistentes o refractarios con conjugados polimericos de brazos multiples de 7-etil-10-hidroxicamptotecina.
|
|
BRPI0810717A2
(pt)
*
|
2007-04-30 |
2016-05-24 |
Arqule Inc |
sulfonato hidroxi de composto de quinona e seus usos
|
|
CA2707840A1
(en)
*
|
2007-08-20 |
2009-02-26 |
Allozyne, Inc. |
Amino acid substituted molecules
|
|
BRPI0721948A2
(pt)
*
|
2007-08-20 |
2014-04-08 |
Enzon Pharmaceuticals Inc |
Ligantes poliméricos contendo frações dissulfeto de piridila
|
|
US8703878B2
(en)
|
2007-09-28 |
2014-04-22 |
Nippon Kayaku Kabushiki Kaisha |
High-molecular weight conjugate of steroids
|
|
MX2010004400A
(es)
*
|
2007-10-23 |
2010-05-20 |
Nektar Therapeutics |
Polimeros de multiples brazos dirigidos a la hidroxiapatita y conjugados de estos.
|
|
EP2070951A1
(en)
*
|
2007-12-14 |
2009-06-17 |
Fresenius Kabi Deutschland GmbH |
Method for producing a hydroxyalkyl starch derivatives with two linkers
|
|
EP2070950A1
(en)
*
|
2007-12-14 |
2009-06-17 |
Fresenius Kabi Deutschland GmbH |
Hydroxyalkyl starch derivatives and process for their preparation
|
|
KR101589582B1
(ko)
|
2008-03-18 |
2016-01-28 |
니폰 가야꾸 가부시끼가이샤 |
생리활성물질의 고분자량 결합체
|
|
JP5366940B2
(ja)
|
2008-05-08 |
2013-12-11 |
日本化薬株式会社 |
葉酸若しくは葉酸誘導体の高分子結合体
|
|
KR101671537B1
(ko)
*
|
2008-08-11 |
2016-11-01 |
넥타르 테라퓨틱스 |
다분지형 중합체 알카노에이트 컨쥬게이트
|
|
TW201010732A
(en)
*
|
2008-08-29 |
2010-03-16 |
Enzon Pharmaceuticals Inc |
Method of treating RAS associated cancer
|
|
EP2350118B1
(en)
|
2008-09-19 |
2016-03-30 |
Nektar Therapeutics |
Carbohydrate-based drug delivery polymers and conjugates thereof
|
|
EP2340047A1
(en)
*
|
2008-09-19 |
2011-07-06 |
Nektar Therapeutics |
Polymer conjugates of kiss1 peptides
|
|
EP2340045B1
(en)
|
2008-09-19 |
2017-04-12 |
Nektar Therapeutics |
Polymer conjugates of protegrin peptides
|
|
US20110206633A1
(en)
*
|
2008-09-19 |
2011-08-25 |
Nektar Therapectics |
Polymer conjugates of cd-np peptides
|
|
US20110171166A1
(en)
*
|
2008-09-19 |
2011-07-14 |
Nektar Therapeutics |
Polymer conjugates of osteocalcin peptides
|
|
AU2009292651A1
(en)
*
|
2008-09-19 |
2010-03-25 |
Nektar Therapeutics |
Polymer conjugates of AOD-like peptides
|
|
EP2340046A2
(en)
*
|
2008-09-19 |
2011-07-06 |
Nektar Therapeutics |
Polymer conjugates of ziconotide peptides
|
|
WO2010033223A1
(en)
*
|
2008-09-19 |
2010-03-25 |
Nektar Therapeutics |
Polymer conjugates of opioid growth factor peptides
|
|
WO2010033204A2
(en)
*
|
2008-09-19 |
2010-03-25 |
Nektar Therapeutics |
Polymer conjugates of c-peptides
|
|
US20110171162A1
(en)
*
|
2008-09-19 |
2011-07-14 |
Nektar Therapeutics |
Polymer conjugates of thymosin alpha 1 peptides
|
|
US20110171164A1
(en)
*
|
2008-09-19 |
2011-07-14 |
Nektar Therapeutics |
Polymer conjugates of glp-2-like peptides
|
|
US20110165113A1
(en)
*
|
2008-09-19 |
2011-07-07 |
Nektar Therapeutics |
Polymer conjugates of v681-like peptides
|
|
MX2011003063A
(es)
|
2008-09-23 |
2011-04-21 |
Nektar Therapeutics |
Composiciones y metodos para lograr concentraciones terapeuticas de farmaco sostenidas en un individuo.
|
|
US20100098654A1
(en)
*
|
2008-10-21 |
2010-04-22 |
Fabio Pastorino |
Treatment of neuroblastoma with multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin
|
|
JP5544357B2
(ja)
|
2009-05-15 |
2014-07-09 |
日本化薬株式会社 |
水酸基を有する生理活性物質の高分子結合体
|
|
JP2013533217A
(ja)
|
2010-05-17 |
2013-08-22 |
セビックス・インコーポレイテッド |
Peg化c−ペプチド
|
|
WO2012004006A1
(en)
|
2010-07-09 |
2012-01-12 |
Fresenius Kabi Deutschland Gmbh |
Conjugates comprising hydroxyalkyl starch and a cytotoxic agent and process for their preparation
|
|
US20130217871A1
(en)
|
2010-07-09 |
2013-08-22 |
Helmut Knoller |
Conjugates comprising hydroxyalkyl starch and a cytotoxic agent and process for their preparation
|
|
EP2591008A1
(en)
|
2010-07-09 |
2013-05-15 |
Fresenius Kabi Deutschland GmbH |
Conjugates comprising hydroxyalkyl starch and a cytotoxic agent and process for their preparation
|
|
WO2012004007A1
(en)
|
2010-07-09 |
2012-01-12 |
Fresenius Kabi Deutschland Gmbh |
Conjugates comprising hydroxyalkyl starch and a cytotoxic agent and process for their preparation
|
|
CN102339813A
(zh)
|
2010-07-14 |
2012-02-01 |
中国科学院微电子研究所 |
半导体结构及其制造方法
|
|
JP5856069B2
(ja)
|
2010-11-17 |
2016-02-09 |
日本化薬株式会社 |
新規なシチジン系代謝拮抗剤の高分子誘導体
|
|
US20130331443A1
(en)
|
2010-12-22 |
2013-12-12 |
Nektar Therapeutics |
Multi-arm polymeric prodrug conjugates of taxane-based compounds
|
|
US10894087B2
(en)
|
2010-12-22 |
2021-01-19 |
Nektar Therapeutics |
Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds
|
|
HUE052285T2
(hu)
*
|
2011-06-06 |
2021-04-28 |
Starpharma Pty Ltd |
Makromolekulák
|
|
AU2012278944B2
(en)
|
2011-07-05 |
2015-09-17 |
Bioasis Technologies Inc. |
p97-antibody conjugates and methods of use
|
|
JP5711378B2
(ja)
|
2011-09-11 |
2015-04-30 |
日本化薬株式会社 |
ブロック共重合体の製造方法
|
|
CN103083680B
(zh)
|
2011-11-07 |
2014-12-24 |
北京键凯科技有限公司 |
聚乙二醇-氨基酸寡肽-依诺替康药物结合物及其药物组合物
|
|
PL2797416T3
(pl)
|
2011-12-28 |
2017-12-29 |
Global Blood Therapeutics, Inc. |
Podstawione związki benzaldehydowe i sposoby ich zastosowania do zwiększania natlenienia tkanek
|
|
US9012450B2
(en)
|
2011-12-28 |
2015-04-21 |
Global Blood Therapeutics, Inc. |
Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation
|
|
WO2014022515A1
(en)
|
2012-07-31 |
2014-02-06 |
Bioasis Technologies, Inc. |
Dephosphorylated lysosomal storage disease proteins and methods of use thereof
|
|
CN104884056A
(zh)
|
2012-11-12 |
2015-09-02 |
雷德伍德生物科技股份有限公司 |
用于制备缀合物的化合物和方法
|
|
US9310374B2
(en)
|
2012-11-16 |
2016-04-12 |
Redwood Bioscience, Inc. |
Hydrazinyl-indole compounds and methods for producing a conjugate
|
|
WO2014078733A1
(en)
|
2012-11-16 |
2014-05-22 |
The Regents Of The University Of California |
Pictet-spengler ligation for protein chemical modification
|
|
NZ711373A
(en)
|
2013-03-13 |
2020-07-31 |
Bioasis Technologies Inc |
Fragments of p97 and uses thereof
|
|
US10266551B2
(en)
|
2013-03-15 |
2019-04-23 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
|
US8952171B2
(en)
|
2013-03-15 |
2015-02-10 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
|
BR112015021982B1
(pt)
|
2013-03-15 |
2022-12-13 |
Global Blood Therapeutics, Inc |
Compostos e seus usos para a modulação de hemoglobina
|
|
US9422279B2
(en)
|
2013-03-15 |
2016-08-23 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
|
EP2968299B1
(en)
|
2013-03-15 |
2021-01-20 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
|
JP6426694B2
(ja)
|
2013-03-15 |
2018-11-21 |
グローバル ブラッド セラピューティクス インコーポレイテッド |
ヘモグロビンの修飾のための化合物及びその使用
|
|
US9458139B2
(en)
|
2013-03-15 |
2016-10-04 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
|
US20140274961A1
(en)
|
2013-03-15 |
2014-09-18 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
|
US9802900B2
(en)
|
2013-03-15 |
2017-10-31 |
Global Blood Therapeutics, Inc. |
Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
|
|
US9604999B2
(en)
|
2013-03-15 |
2017-03-28 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
|
WO2014145040A1
(en)
|
2013-03-15 |
2014-09-18 |
Global Blood Therapeutics, Inc. |
Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
|
|
US20150093399A1
(en)
|
2013-08-28 |
2015-04-02 |
Bioasis Technologies, Inc. |
Cns-targeted conjugates having modified fc regions and methods of use thereof
|
|
EA201992707A1
(ru)
|
2013-11-18 |
2020-06-30 |
Глобал Блад Терапьютикс, Инк. |
Соединения и их применения для модуляции гемоглобина
|
|
CN115504924A
(zh)
|
2013-11-27 |
2022-12-23 |
雷德伍德生物科技股份有限公司 |
肼基-吡咯并化合物及用于生成缀合物的方法
|
|
AP2016009261A0
(en)
|
2014-02-07 |
2016-06-30 |
Global Blood Therapeutics Inc |
Crystalline polymorphs of the free base of 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
|
|
MA41841A
(fr)
|
2015-03-30 |
2018-02-06 |
Global Blood Therapeutics Inc |
Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs
|
|
CN106937529B
(zh)
|
2015-10-27 |
2021-02-05 |
加州太平洋医疗中心 |
鬼臼毒素衍生物及其应用
|
|
US10087194B2
(en)
|
2015-10-27 |
2018-10-02 |
California Pacific Medical Center |
Podophyllotoxin derivatives and their use
|
|
WO2017083306A1
(en)
|
2015-11-09 |
2017-05-18 |
R.P. Scherer Technologies, Llc |
Anti-cd22 antibody-maytansine conjugates and methods of use thereof
|
|
PL3383392T3
(pl)
|
2015-12-04 |
2025-11-17 |
Global Blood Therapeutics, Inc. |
Schematy dawkowania dla 2-hydroksy-6-((2-(1-izopropylo-1H-pirazol-5-ilo)pirydyn3-ylo)metoksy)benzaldehydu
|
|
WO2017180998A2
(en)
|
2016-04-15 |
2017-10-19 |
Beckman Coulter, Inc. |
Photoactive macromolecules and uses thereof
|
|
TWI663160B
(zh)
|
2016-05-12 |
2019-06-21 |
全球血液治療公司 |
用於合成2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)-吡啶-3-基)甲氧基)苯甲醛之方法
|
|
TW202332423A
(zh)
|
2016-10-12 |
2023-08-16 |
美商全球血液治療公司 |
包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
|
|
KR20220147719A
(ko)
|
2016-11-14 |
2022-11-03 |
항저우 디에이씨 바이오테크 씨오, 엘티디 |
결합 링커, 그러한 결합 링커를 함유하는 세포 결합 분자-약물 결합체, 링커를 갖는 그러한 결합체의 제조 및 사용
|
|
CN109923179A
(zh)
|
2016-12-12 |
2019-06-21 |
贝克顿·迪金森公司 |
水溶性聚合物染料
|
|
US12344645B2
(en)
|
2017-03-29 |
2025-07-01 |
Polaris Group |
Protein conjugates
|
|
WO2019133399A1
(en)
|
2017-12-26 |
2019-07-04 |
Becton, Dickinson And Company |
Deep ultraviolet-excitable water-solvated polymeric dyes
|
|
CN112384573A
(zh)
|
2018-03-30 |
2021-02-19 |
贝克顿·迪金森公司 |
含侧基发色团的水溶性聚合染料
|
|
EP3823961A4
(en)
|
2018-07-19 |
2022-06-08 |
Starpharma Pty Limited |
THERAPEUTIC DENDRIMER
|
|
US12071517B2
(en)
|
2018-07-19 |
2024-08-27 |
Starpharma Pty Ltd. |
Therapeutic dendrimer
|
|
EP3813867A1
(en)
|
2018-07-22 |
2021-05-05 |
Bioasis Technologies Inc. |
Treatment of lymmphatic metastases
|
|
CN121554542A
(zh)
|
2018-08-22 |
2026-02-24 |
贝凯恩生物医疗技术有限公司 |
环孢菌素组合物及使用方法
|
|
CN110862400A
(zh)
*
|
2018-08-27 |
2020-03-06 |
遵义医学院 |
喜树碱-羟基乙酸中间体的制备工艺
|
|
EP3860975B1
(en)
|
2018-10-01 |
2023-10-18 |
Global Blood Therapeutics, Inc. |
Modulators of hemoglobin for the treatment of sickle cell disease
|
|
US12479816B2
(en)
|
2019-02-08 |
2025-11-25 |
University of Pittsburgh—of the Commonwealth System of Higher Education |
20-HETE formation inhibitors
|
|
US20210355468A1
(en)
|
2020-05-18 |
2021-11-18 |
Bioasis Technologies, Inc. |
Compositions and methods for treating lewy body dementia
|
|
US20210393787A1
(en)
|
2020-06-17 |
2021-12-23 |
Bioasis Technologies, Inc. |
Compositions and methods for treating frontotemporal dementia
|
|
CA3128035A1
(en)
|
2020-08-13 |
2022-02-13 |
Bioasis Technologies, Inc. |
Combination therapies for delivery across the blood brain barrier
|
|
EP4155349A1
(en)
|
2021-09-24 |
2023-03-29 |
Becton, Dickinson and Company |
Water-soluble yellow green absorbing dyes
|
|
CN117980327A
(zh)
|
2021-11-03 |
2024-05-03 |
杭州多禧生物科技有限公司 |
抗体的特异性偶联
|
|
US20250383357A1
(en)
|
2022-07-01 |
2025-12-18 |
Beckman Coulter, Inc. |
Novel fluorescent dyes and polymers from dihydrophenanthrene derivatives
|
|
WO2024044327A1
(en)
|
2022-08-26 |
2024-02-29 |
Beckman Coulter, Inc. |
Dhnt monomers and polymer dyes with modified photophysical properties
|
|
WO2024196805A1
(en)
|
2023-03-17 |
2024-09-26 |
Beckman Coulter, Inc. |
Benzothienopyrrole cyanine dyes
|
|
CN121866309A
(zh)
|
2023-09-21 |
2026-04-14 |
贝克曼库尔特有限公司 |
用于流式细胞术的二氢菲(dhp)桥接染料
|