KR100361933B1
(ko)
|
1993-09-08 |
2003-02-14 |
라 졸라 파마슈티칼 컴파니 |
화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트
|
US5965566A
(en)
*
|
1993-10-20 |
1999-10-12 |
Enzon, Inc. |
High molecular weight polymer-based prodrugs
|
US6096336A
(en)
*
|
1996-01-30 |
2000-08-01 |
The Stehlin Foundation For Cancer Research |
Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs
|
JP3737518B2
(ja)
*
|
1996-03-12 |
2006-01-18 |
ピージー−ティーエックスエル カンパニー, エル.ピー. |
水溶性パクリタキセルプロドラッグ
|
US6214966B1
(en)
|
1996-09-26 |
2001-04-10 |
Shearwater Corporation |
Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution
|
US20050158273A1
(en)
*
|
1997-09-25 |
2005-07-21 |
Harris J. M. |
Soluble, degradable polyethylene glycol) derivatives for controllable release of bound molecules into solution
|
US6011042A
(en)
*
|
1997-10-10 |
2000-01-04 |
Enzon, Inc. |
Acyl polymeric derivatives of aromatic hydroxyl-containing compounds
|
US6111107A
(en)
*
|
1997-11-20 |
2000-08-29 |
Enzon, Inc. |
High yield method for stereoselective acylation of tertiary alcohols
|
WO1999030727A1
(en)
|
1997-12-17 |
1999-06-24 |
Enzon, Inc. |
Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents
|
US6180095B1
(en)
*
|
1997-12-17 |
2001-01-30 |
Enzon, Inc. |
Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents
|
US6362276B1
(en)
*
|
1998-01-07 |
2002-03-26 |
Debio Recherche Pharmaceutique S.A. |
Degradable heterobifunctional poly(ethylene glycol) acrylates and gels and conjugates derived therefrom
|
US6153655A
(en)
*
|
1998-04-17 |
2000-11-28 |
Enzon, Inc. |
Terminally-branched polymeric linkers and polymeric conjugates containing the same
|
ATE399567T1
(de)
|
1998-04-28 |
2008-07-15 |
Serono Lab |
Peg konjugate von lhrh analogen
|
US7953788B2
(en)
*
|
2001-09-29 |
2011-05-31 |
Siebel Systems, Inc. |
System and method for queuing data for an application server
|
EP1183230A1
(en)
*
|
1999-06-08 |
2002-03-06 |
La Jolla Pharmaceutical |
Valency platform molecules comprising aminooxy groups
|
WO2001005819A1
(en)
*
|
1999-07-15 |
2001-01-25 |
Kuhnil Pharm. Co., Ltd. |
Novel water soluble-cyclosporine conjugated compounds
|
US6352996B1
(en)
|
1999-08-03 |
2002-03-05 |
The Stehlin Foundation For Cancer Research |
Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs
|
US6228855B1
(en)
*
|
1999-08-03 |
2001-05-08 |
The Stehlin Foundation For Cancer Research |
Aromatic esters of camptothecins and methods to treat cancers
|
US6713454B1
(en)
*
|
1999-09-13 |
2004-03-30 |
Nobex Corporation |
Prodrugs of etoposide and etoposide analogs
|
US6380405B1
(en)
*
|
1999-09-13 |
2002-04-30 |
Nobex Corporation |
Taxane prodrugs
|
US6541508B2
(en)
|
1999-09-13 |
2003-04-01 |
Nobex Corporation |
Taxane prodrugs
|
US6376470B1
(en)
*
|
1999-09-23 |
2002-04-23 |
Enzon, Inc. |
Polymer conjugates of ara-C and ara-C derivatives
|
EP2266607A3
(en)
|
1999-10-01 |
2011-04-20 |
Immunogen, Inc. |
Immunoconjugates for treating cancer
|
AU781839B2
(en)
|
1999-12-22 |
2005-06-16 |
Nektar Therapeutics |
Sterically hindered derivatives of water soluble polymers
|
AU2001257577A1
(en)
|
2000-02-28 |
2001-09-03 |
Shearwater Corporation |
Water-soluble polymer conjugates of artelinic acid
|
CN1434726A
(zh)
|
2000-06-08 |
2003-08-06 |
拉卓拉药物公司 |
包含高分子量聚环氧乙烷的多价平台分子
|
BR0112428A
(pt)
*
|
2000-07-12 |
2003-11-25 |
Gryphon Therapeutics Inc |
Quimiocinas sintéticas boativas modificadas por polìmero e métodos para sua produção e uso
|
US7118737B2
(en)
*
|
2000-09-08 |
2006-10-10 |
Amylin Pharmaceuticals, Inc. |
Polymer-modified synthetic proteins
|
AU2001273385B2
(en)
*
|
2000-09-08 |
2005-04-07 |
Gryphon Therapeutics, Inc. |
Polymer-modified synthetic proteins
|
US6436386B1
(en)
|
2000-11-14 |
2002-08-20 |
Shearwater Corporation |
Hydroxyapatite-targeting poly (ethylene glycol) and related polymers
|
US7829074B2
(en)
*
|
2001-10-18 |
2010-11-09 |
Nektar Therapeutics |
Hydroxypatite-targeting poly(ethylene glycol) and related polymers
|
JP2004530736A
(ja)
*
|
2001-02-20 |
2004-10-07 |
エンゾン ファーマシューティカルズ,インコーポレーテッド |
末端分枝高分子リンカーおよびそれを含む高分子複合体
|
MXPA03007392A
(es)
*
|
2001-02-20 |
2003-12-04 |
Enzon Inc |
Enlazantes polimericos ramificados terminalmente y conjugados polimericos que contienen los mismos.
|
US20040077835A1
(en)
*
|
2001-07-12 |
2004-04-22 |
Robin Offord |
Chemokine receptor modulators, production and use
|
ATE452654T1
(de)
*
|
2001-11-09 |
2010-01-15 |
Enzon Inc |
Polyalkylenoxid-konjugate von thiolhaltigen arzneistoffen
|
GB0202906D0
(en)
*
|
2002-02-07 |
2002-03-27 |
Univ London |
Prevention of myocardial damage
|
DE10209821A1
(de)
|
2002-03-06 |
2003-09-25 |
Biotechnologie Ges Mittelhesse |
Kopplung von Proteinen an ein modifiziertes Polysaccharid
|
DE10209822A1
(de)
*
|
2002-03-06 |
2003-09-25 |
Biotechnologie Ges Mittelhesse |
Kopplung niedermolekularer Substanzen an ein modifiziertes Polysaccharid
|
US8003089B2
(en)
*
|
2002-03-13 |
2011-08-23 |
Beijing Jiankai Technology Co., Ltd. |
Y shape branched hydrophilic polymer derivatives, their preparation methods, conjugates of the derivatives and drug molecules, and pharmaceutical compositions comprising the conjugates
|
CA2479810A1
(en)
*
|
2002-04-04 |
2003-10-16 |
Enzon, Inc. |
Polymeric acyl derivatives of indoles
|
CN100393724C
(zh)
*
|
2002-07-12 |
2008-06-11 |
中国医学科学院药物研究所 |
20-位酯化的喜树碱衍生物及其制法和其药物组合物与用途
|
JP4764630B2
(ja)
*
|
2002-09-09 |
2011-09-07 |
ネクター セラピューティックス |
水溶性ポリマーアルカナール
|
ES2315526T3
(es)
*
|
2002-09-09 |
2009-04-01 |
Nektar Therapeutics Al, Corporation |
Metodo para preparar derivados polimericos solubles en agua que llevan un acido carboxilico terminal.
|
WO2004024776A1
(en)
*
|
2002-09-11 |
2004-03-25 |
Fresenius Kabi Deutschland Gmbh |
Method of producing hydroxyalkyl starch derivatives
|
US20040062748A1
(en)
|
2002-09-30 |
2004-04-01 |
Mountain View Pharmaceuticals, Inc. |
Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
|
US8129330B2
(en)
*
|
2002-09-30 |
2012-03-06 |
Mountain View Pharmaceuticals, Inc. |
Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
|
WO2004039869A1
(ja)
|
2002-10-31 |
2004-05-13 |
Nippon Kayaku Kabushiki Kaisha |
カンプトテシン類の高分子誘導体
|
WO2004061094A1
(en)
|
2002-12-30 |
2004-07-22 |
Gryphon Therapeutics, Inc. |
Water-soluble thioester and selenoester compounds and methods for making and using the same
|
CA2518265A1
(en)
*
|
2003-03-17 |
2004-09-30 |
Albany Molecular Research, Inc. |
Novel cyclosporins
|
US7947261B2
(en)
|
2003-05-23 |
2011-05-24 |
Nektar Therapeutics |
Conjugates formed from polymer derivatives having particular atom arrangements
|
TR201907313T4
(tr)
*
|
2003-05-23 |
2019-06-21 |
Nektar Therapeutics |
İki PEG zinciri içeren PEG türevleri.
|
US7342114B2
(en)
*
|
2003-07-01 |
2008-03-11 |
California Pacific Medical Center |
Podophyllotoxin derivatives
|
WO2005014655A2
(en)
*
|
2003-08-08 |
2005-02-17 |
Fresenius Kabi Deutschland Gmbh |
Conjugates of hydroxyalkyl starch and a protein
|
US20080274948A1
(en)
*
|
2003-08-08 |
2008-11-06 |
Fresenius Kabi Deutschland Gmbh |
Conjugates of Hydroxyalkyl Starch and G-Csf
|
CN1852740B
(zh)
*
|
2003-09-17 |
2011-05-11 |
耐科塔医药公司 |
多支链聚合物的药物前体
|
US8394365B2
(en)
|
2003-09-17 |
2013-03-12 |
Nektar Therapeutics |
Multi-arm polymer prodrugs
|
US20050153371A1
(en)
*
|
2004-01-07 |
2005-07-14 |
Ambit Biosciences Corporation |
Conjugated small molecules
|
EP1756173B1
(en)
*
|
2004-01-21 |
2019-04-03 |
Nektar Therapeutics |
Method of preparing propionic acid-terminated polymers
|
CN102302787A
(zh)
*
|
2004-03-11 |
2012-01-04 |
费森尤斯卡比德国有限公司 |
羟烷基淀粉和蛋白质的接合物
|
WO2005092928A1
(en)
|
2004-03-11 |
2005-10-06 |
Fresenius Kabi Deutschland Gmbh |
Conjugates of hydroxyalkyl starch and a protein, prepared by reductive amination
|
CA2563502A1
(en)
*
|
2004-04-09 |
2005-10-20 |
Chugai Seiyaku Kabushiki Kaisha |
Novel water-soluble prodrug
|
WO2006020719A2
(en)
*
|
2004-08-11 |
2006-02-23 |
Arqule, Inc. |
Aminoacid conjugates of beta - lapachone for tumor targeting
|
US8614228B2
(en)
|
2004-08-11 |
2013-12-24 |
Arqule, Inc. |
Quinone prodrug compositions and methods of use
|
CN101023119B
(zh)
|
2004-09-22 |
2010-05-05 |
日本化药株式会社 |
新型嵌段共聚物,胶束制剂以及含胶束制剂为活性组分的抗癌剂
|
WO2006039164A2
(en)
*
|
2004-09-29 |
2006-04-13 |
Amr Technology, Inc. |
Novel cyclosporin analogues and their pharmaceutical uses
|
WO2006039163A2
(en)
*
|
2004-09-29 |
2006-04-13 |
Amr Technology, Inc. |
Cyclosporin alkyne analogues and their pharmaceutical uses
|
WO2006041631A2
(en)
*
|
2004-10-06 |
2006-04-20 |
Amr Technology, Inc. |
Novel cyclosporin alkynes and their utility as pharmaceutical agents
|
US7662781B2
(en)
|
2005-01-31 |
2010-02-16 |
Eci, Inc. |
Immunopotentiating agent
|
AU2006222187A1
(en)
*
|
2005-03-11 |
2006-09-14 |
Fresenius Kabi Deutschland Gmbh |
Production of bioactive glycoproteins from inactive starting material by conjugation with hydroxyalkylstarch
|
WO2006097682A1
(en)
*
|
2005-03-18 |
2006-09-21 |
Ucl Business Plc |
Mechano growth factor peptides and their use
|
WO2006105993A2
(en)
|
2005-04-05 |
2006-10-12 |
Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa |
Method for shielding functional sites or epitopes on proteins
|
TW200744603A
(en)
|
2005-08-22 |
2007-12-16 |
Chugai Pharmaceutical Co Ltd |
Novel anticancer concomitant drug
|
EP1762250A1
(en)
*
|
2005-09-12 |
2007-03-14 |
Fresenius Kabi Deutschland GmbH |
Conjugates of hydroxyalkyl starch and an active substance, prepared by chemical ligation via thiazolidine
|
JP5096363B2
(ja)
*
|
2005-12-16 |
2012-12-12 |
ネクター セラピューティックス |
Glp−1のポリマ複合体
|
US7671067B2
(en)
*
|
2006-02-09 |
2010-03-02 |
Enzon Pharmaceuticals, Inc. |
Treatment of non-hodgkin's lymphomas with multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamtothecin
|
US7462627B2
(en)
*
|
2006-02-09 |
2008-12-09 |
Enzon Pharmaceuticals, Inc. |
Multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin for treatment of breast, colorectal, pancreatic, ovarian and lung cancers
|
AU2007216998B8
(en)
|
2006-02-21 |
2013-12-19 |
Nektar Therapeutics |
Segmented degradable polymers and conjugates made therefrom
|
US7696165B2
(en)
*
|
2006-03-28 |
2010-04-13 |
Albany Molecular Research, Inc. |
Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
|
KR20080106254A
(ko)
|
2006-03-28 |
2008-12-04 |
니폰 가야꾸 가부시끼가이샤 |
탁산류의 고분자 결합체
|
US7696166B2
(en)
*
|
2006-03-28 |
2010-04-13 |
Albany Molecular Research, Inc. |
Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
|
EP2018437A2
(en)
|
2006-05-02 |
2009-01-28 |
Allozyne, Inc. |
Non-natural amino acid substituted polypeptides
|
US20080096819A1
(en)
*
|
2006-05-02 |
2008-04-24 |
Allozyne, Inc. |
Amino acid substituted molecules
|
WO2007135910A1
(ja)
|
2006-05-18 |
2007-11-29 |
Nippon Kayaku Kabushiki Kaisha |
ポドフィロトキシン類の高分子結合体
|
EP2102144A4
(en)
|
2006-09-13 |
2011-03-23 |
Univ Rutgers |
ACTIVE SUBSTANCES AND THEIR OLIGOMERS AND POLYMERS
|
CA2662973A1
(en)
*
|
2006-09-15 |
2008-03-20 |
Enzon Pharmaceuticals, Inc. |
Lysine-based polymeric linkers
|
US8110559B2
(en)
*
|
2006-09-15 |
2012-02-07 |
Enzon Pharmaceuticals, Inc. |
Hindered ester-based biodegradable linkers for oligonucleotide delivery
|
MX2009002854A
(es)
*
|
2006-09-15 |
2009-03-27 |
Enzon Pharmaceuticals Inc |
Oxidos de polialquileno que tienen enlazadores biodegradables a base de ester impedido.
|
US7985783B2
(en)
|
2006-09-21 |
2011-07-26 |
The Regents Of The University Of California |
Aldehyde tags, uses thereof in site-specific protein modification
|
CA2664852A1
(en)
*
|
2006-10-03 |
2008-04-10 |
Nippon Kayaku Kabushiki Kaisha |
High-molecular weight conjugate of resorcinol derivatives
|
WO2008056596A1
(en)
|
2006-11-06 |
2008-05-15 |
Nippon Kayaku Kabushiki Kaisha |
Polymeric derivative of nucleic acid metabolic antagonist
|
EP2090607B1
(en)
|
2006-11-08 |
2015-05-20 |
Nippon Kayaku Kabushiki Kaisha |
Polymeric derivative of nucleic acid metabolic antagonist
|
KR101441709B1
(ko)
|
2006-11-30 |
2014-09-18 |
넥타르 테라퓨틱스 |
중합체 컨쥬게이트의 제조 방법
|
KR20090108082A
(ko)
*
|
2007-02-09 |
2009-10-14 |
엔존 파마슈티컬즈, 인코포레이티드 |
7-에틸-10-하이드록시캄토테신 다분지형 고분자 접합체를 이용한 내성 또는 불응성 암의 치료방법
|
CN101687835B
(zh)
*
|
2007-04-30 |
2015-08-19 |
艾科尔公司 |
苯醌化合物的羟基磺酸盐和它们的应用
|
CA2707840A1
(en)
|
2007-08-20 |
2009-02-26 |
Allozyne, Inc. |
Amino acid substituted molecules
|
BRPI0721948A2
(pt)
*
|
2007-08-20 |
2014-04-08 |
Enzon Pharmaceuticals Inc |
Ligantes poliméricos contendo frações dissulfeto de piridila
|
WO2009041570A1
(ja)
|
2007-09-28 |
2009-04-02 |
Nippon Kayaku Kabushiki Kaisha |
ステロイド類の高分子結合体
|
EP2214716B1
(en)
|
2007-10-23 |
2021-11-17 |
Nektar Therapeutics |
Hydroxyapatite-targeting multiarm polymers and conjugates made therefrom
|
EP2070950A1
(en)
*
|
2007-12-14 |
2009-06-17 |
Fresenius Kabi Deutschland GmbH |
Hydroxyalkyl starch derivatives and process for their preparation
|
EP2070951A1
(en)
*
|
2007-12-14 |
2009-06-17 |
Fresenius Kabi Deutschland GmbH |
Method for producing a hydroxyalkyl starch derivatives with two linkers
|
CN101977631A
(zh)
|
2008-03-18 |
2011-02-16 |
日本化药株式会社 |
生理活性物质的高分子量偶联物
|
WO2009136572A1
(ja)
|
2008-05-08 |
2009-11-12 |
日本化薬株式会社 |
葉酸若しくは葉酸誘導体の高分子結合体
|
CA2732508C
(en)
|
2008-08-11 |
2016-03-15 |
Nektar Therapeutics |
Multi-arm polymeric alkanoate conjugates
|
WO2010025337A1
(en)
*
|
2008-08-29 |
2010-03-04 |
Enzon Pharmaceuticals, Inc. |
Method of treating ras associated cancer
|
WO2010033221A1
(en)
|
2008-09-19 |
2010-03-25 |
Nektar Therapeutics |
Polymer conjugates of protegrin peptides
|
WO2010033224A1
(en)
*
|
2008-09-19 |
2010-03-25 |
Nektar Therapeutics |
Polymer conjugates of kiss1 peptides
|
US20110171164A1
(en)
*
|
2008-09-19 |
2011-07-14 |
Nektar Therapeutics |
Polymer conjugates of glp-2-like peptides
|
EP2344199A1
(en)
*
|
2008-09-19 |
2011-07-20 |
Nektar Therapeutics |
Polymer conjugates of thymosin alpha 1 peptides
|
US20110171163A1
(en)
*
|
2008-09-19 |
2011-07-14 |
Nektar Therapeutics |
Polymer conjugates of ziconotide peptides
|
WO2010033215A2
(en)
*
|
2008-09-19 |
2010-03-25 |
Nektar Therapeutics |
Polymer conjugates of aod-like peptides
|
US20110171166A1
(en)
*
|
2008-09-19 |
2011-07-14 |
Nektar Therapeutics |
Polymer conjugates of osteocalcin peptides
|
WO2010033240A2
(en)
|
2008-09-19 |
2010-03-25 |
Nektar Therapeutics |
Carbohydrate-based drug delivery polymers and conjugates thereof
|
EP2334337A1
(en)
*
|
2008-09-19 |
2011-06-22 |
Nektar Therapeutics |
Polymer conjugates of opioid growth factor peptides
|
US20110165112A1
(en)
*
|
2008-09-19 |
2011-07-07 |
Nektar Therapeutics |
Polymer conjugates of c-peptides
|
US20110206633A1
(en)
*
|
2008-09-19 |
2011-08-25 |
Nektar Therapectics |
Polymer conjugates of cd-np peptides
|
WO2010033205A1
(en)
*
|
2008-09-19 |
2010-03-25 |
Nektar Therapeutics |
Polymer conjugates of v681-like peptides
|
PT2349346T
(pt)
|
2008-09-23 |
2019-10-24 |
Nektar Therapeutics |
Método de dosagem metronómica com profármacos de camptotecina (e.g. peg-irinotecano).
|
WO2010048018A1
(en)
*
|
2008-10-21 |
2010-04-29 |
Enzon Pharmaceuticals, Inc. |
Treatment of neuroblastoma with multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin
|
US8808749B2
(en)
|
2009-05-15 |
2014-08-19 |
Nippon Kayaku Kabushiki Kaisha |
Polymer conjugate of bioactive substance having hydroxy group
|
KR20130115086A
(ko)
|
2010-05-17 |
2013-10-21 |
세빅스 인코포레이티드 |
페길화된 c-펩티드
|
US20130178437A1
(en)
|
2010-07-09 |
2013-07-11 |
Fresenius Kabi Deutschland Gmbh |
Conjugates comprising hydroxyalkyl starch and a cytotoxic agent and process for their preparation
|
US20140088298A9
(en)
|
2010-07-09 |
2014-03-27 |
Fresenius Kabi Deutschland Gmbh |
Conjugates comprising hydroxyalkyl starch and a cytotoxic agent and process for their preparation
|
WO2012004008A1
(en)
|
2010-07-09 |
2012-01-12 |
Fresenius Kabi Deutschland Gmbh |
Conjugates comprising hydroxyalkyl starch and a cytotoxic agent and process for their preparation
|
WO2012004009A1
(en)
|
2010-07-09 |
2012-01-12 |
Fresenius Kabi Deutschland Gmbh |
Conjugates comprising hydroxyalkyl starch and a cytotoxic agent and process for their preparation
|
CN102339813A
(zh)
|
2010-07-14 |
2012-02-01 |
中国科学院微电子研究所 |
半导体结构及其制造方法
|
EP2641605B1
(en)
|
2010-11-17 |
2018-03-07 |
Nippon Kayaku Kabushiki Kaisha |
Polymer derivative of cytidine metabolism antagonist
|
US10894087B2
(en)
|
2010-12-22 |
2021-01-19 |
Nektar Therapeutics |
Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds
|
US20130331443A1
(en)
|
2010-12-22 |
2013-12-12 |
Nektar Therapeutics |
Multi-arm polymeric prodrug conjugates of taxane-based compounds
|
AU2012267200B2
(en)
*
|
2011-06-06 |
2016-02-25 |
Starpharma Pty Ltd |
Macromolecules
|
JP6208658B2
(ja)
|
2011-07-05 |
2017-10-04 |
バイオアシス テクノロジーズ インコーポレイテッド |
p97−抗体結合体および使用方法
|
RU2623426C2
(ru)
|
2011-09-11 |
2017-06-26 |
Ниппон Каяку Кабусики Кайся |
Способ получения блок-сополимера
|
CN103083680B
(zh)
|
2011-11-07 |
2014-12-24 |
北京键凯科技有限公司 |
聚乙二醇-氨基酸寡肽-依诺替康药物结合物及其药物组合物
|
ES2790358T3
(es)
|
2011-12-28 |
2020-10-27 |
Global Blood Therapeutics Inc |
Compuestos de heteroaril aldehído sustituido y métodos para su uso en el aumento de la oxigenación tisular
|
PT2797416T
(pt)
|
2011-12-28 |
2017-10-23 |
Global Blood Therapeutics Inc |
Compostos de benzaldeído substituído e métodos para a sua utilização no aumento da oxigenação de tecidos
|
EP2880156B1
(en)
|
2012-07-31 |
2017-08-23 |
biOasis Technologies Inc |
Dephosphorylated lysosomal storage disease proteins and methods of use thereof
|
WO2014074218A1
(en)
|
2012-11-12 |
2014-05-15 |
Redwood Bioscience, Inc. |
Compounds and methods for producing a conjugate
|
US9605078B2
(en)
|
2012-11-16 |
2017-03-28 |
The Regents Of The University Of California |
Pictet-Spengler ligation for protein chemical modification
|
US9310374B2
(en)
|
2012-11-16 |
2016-04-12 |
Redwood Bioscience, Inc. |
Hydrazinyl-indole compounds and methods for producing a conjugate
|
CN105263958B
(zh)
|
2013-03-13 |
2019-09-27 |
比奥阿赛斯技术有限公司 |
p97片段及其应用
|
US8952171B2
(en)
|
2013-03-15 |
2015-02-10 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
AP2015008718A0
(en)
|
2013-03-15 |
2015-09-30 |
Global Blood Therapeutics Inc |
Compounds and uses thereof for the modulation of hemoglobin
|
US9802900B2
(en)
|
2013-03-15 |
2017-10-31 |
Global Blood Therapeutics, Inc. |
Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
|
US9422279B2
(en)
|
2013-03-15 |
2016-08-23 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
US9604999B2
(en)
|
2013-03-15 |
2017-03-28 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
US20140274961A1
(en)
|
2013-03-15 |
2014-09-18 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
US10266551B2
(en)
|
2013-03-15 |
2019-04-23 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
MY180206A
(en)
|
2013-03-15 |
2020-11-25 |
Global Blood Therapeutics Inc |
Compounds and uses thereof for the modulation of hemoglobin
|
US9458139B2
(en)
|
2013-03-15 |
2016-10-04 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
US10100043B2
(en)
|
2013-03-15 |
2018-10-16 |
Global Blood Therapeutics, Inc. |
Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
|
CN105073728A
(zh)
|
2013-03-15 |
2015-11-18 |
全球血液疗法股份有限公司 |
化合物及其用于调节血红蛋白的用途
|
EP3038657A2
(en)
|
2013-08-28 |
2016-07-06 |
Bioasis Technologies Inc. |
Cns-targeted conjugates having modified fc regions and methods of use thereof
|
EA201992707A1
(ru)
|
2013-11-18 |
2020-06-30 |
Глобал Блад Терапьютикс, Инк. |
Соединения и их применения для модуляции гемоглобина
|
US9493413B2
(en)
|
2013-11-27 |
2016-11-15 |
Redwood Bioscience, Inc. |
Hydrazinyl-pyrrolo compounds and methods for producing a conjugate
|
DK3102208T3
(da)
|
2014-02-07 |
2021-03-08 |
Global Blood Therapeutics Inc |
Krystallinsk polymorf af den frie base af 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyd
|
MA41841A
(fr)
|
2015-03-30 |
2018-02-06 |
Global Blood Therapeutics Inc |
Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs
|
US10087194B2
(en)
|
2015-10-27 |
2018-10-02 |
California Pacific Medical Center |
Podophyllotoxin derivatives and their use
|
CN106937529B
(zh)
|
2015-10-27 |
2021-02-05 |
加州太平洋医疗中心 |
鬼臼毒素衍生物及其应用
|
MA43373A
(fr)
|
2015-12-04 |
2018-10-10 |
Global Blood Therapeutics Inc |
Régimes posologiques pour 2-hydroxy-6-((2- (1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)méthoxy)benzaldéhyde
|
AR108435A1
(es)
|
2016-05-12 |
2018-08-22 |
Global Blood Therapeutics Inc |
Proceso para sintetizar 2-hidroxi-6-((2-(1-isopropil-1h-pirazol-5-il)-piridin-3-il)metoxi)benzaldehído
|
TWI778983B
(zh)
|
2016-10-12 |
2022-10-01 |
美商全球血液治療公司 |
包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
|
KR20220147720A
(ko)
|
2016-11-14 |
2022-11-03 |
항저우 디에이씨 바이오테크 씨오, 엘티디 |
결합 링커, 그러한 결합 링커를 함유하는 세포 결합 분자-약물 결합체, 링커를 갖는 그러한 결합체의 제조 및 사용
|
CN111094462A
(zh)
|
2017-12-26 |
2020-05-01 |
贝克顿·迪金森公司 |
深紫外线可激发的水溶剂化聚合物染料
|
US10844228B2
(en)
|
2018-03-30 |
2020-11-24 |
Becton, Dickinson And Company |
Water-soluble polymeric dyes having pendant chromophores
|
EP3823961A4
(en)
|
2018-07-19 |
2022-06-08 |
Starpharma Pty Limited |
THERAPEUTIC DENDRIMER
|
WO2020023300A1
(en)
|
2018-07-22 |
2020-01-30 |
Bioasis Technologies, Inc. |
Treatment of lymmphatic metastases
|
WO2020041378A1
(en)
*
|
2018-08-22 |
2020-02-27 |
Bacainn Therapeutics, Inc. |
Cyclosporine compositions and methods of use
|
CN110862400A
(zh)
*
|
2018-08-27 |
2020-03-06 |
遵义医学院 |
喜树碱-羟基乙酸中间体的制备工艺
|
WO2020072377A1
(en)
|
2018-10-01 |
2020-04-09 |
Global Blood Therapeutics, Inc. |
Modulators of hemoglobin for the treatment of sickle cell disease
|
US20210355468A1
(en)
|
2020-05-18 |
2021-11-18 |
Bioasis Technologies, Inc. |
Compositions and methods for treating lewy body dementia
|
US20210393787A1
(en)
|
2020-06-17 |
2021-12-23 |
Bioasis Technologies, Inc. |
Compositions and methods for treating frontotemporal dementia
|
EP3954393A1
(en)
|
2020-08-13 |
2022-02-16 |
Bioasis Technologies Inc. |
Combination therapies for delivery across the blood brain barrier
|
EP4155349A1
(en)
|
2021-09-24 |
2023-03-29 |
Becton, Dickinson and Company |
Water-soluble yellow green absorbing dyes
|
WO2024007016A2
(en)
|
2022-07-01 |
2024-01-04 |
Beckman Coulter, Inc. |
Novel fluorescent dyes and polymers from dihydrophenanthrene derivatives
|
WO2024044327A1
(en)
|
2022-08-26 |
2024-02-29 |
Beckman Coulter, Inc. |
Dhnt monomers and polymer dyes with modified photophysical properties
|