JP2000516463A5 - - Google Patents

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Publication number
JP2000516463A5
JP2000516463A5 JP1998509392A JP50939298A JP2000516463A5 JP 2000516463 A5 JP2000516463 A5 JP 2000516463A5 JP 1998509392 A JP1998509392 A JP 1998509392A JP 50939298 A JP50939298 A JP 50939298A JP 2000516463 A5 JP2000516463 A5 JP 2000516463A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP1998509392A
Other languages
English (en)
Japanese (ja)
Other versions
JP2000516463A (ja
Filing date
Publication date
Priority claimed from DE19632532A external-priority patent/DE19632532A1/de
Application filed filed Critical
Publication of JP2000516463A publication Critical patent/JP2000516463A/ja
Publication of JP2000516463A5 publication Critical patent/JP2000516463A5/ja
Withdrawn legal-status Critical Current

Links

JP10509392A 1996-08-13 1997-08-09 特定の遺伝的特性を有する哺乳動物を作製する方法 Withdrawn JP2000516463A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19632532.3 1996-08-13
DE19632532A DE19632532A1 (de) 1996-08-13 1996-08-13 Verfahren zur Herstellung von Säugetieren mit definierten genetischen Eigenschaften
PCT/EP1997/004352 WO1998006834A1 (de) 1996-08-13 1997-08-09 Verfahren zur herstellung von säugetieren mit definierten genetischen eigenschaften

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2006218386A Division JP4129472B2 (ja) 1996-08-13 2006-08-10 特定の遺伝的特性を有する哺乳動物を作製する方法

Publications (2)

Publication Number Publication Date
JP2000516463A JP2000516463A (ja) 2000-12-12
JP2000516463A5 true JP2000516463A5 (enExample) 2005-04-07

Family

ID=7802466

Family Applications (2)

Application Number Title Priority Date Filing Date
JP10509392A Withdrawn JP2000516463A (ja) 1996-08-13 1997-08-09 特定の遺伝的特性を有する哺乳動物を作製する方法
JP2006218386A Expired - Lifetime JP4129472B2 (ja) 1996-08-13 2006-08-10 特定の遺伝的特性を有する哺乳動物を作製する方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2006218386A Expired - Lifetime JP4129472B2 (ja) 1996-08-13 2006-08-10 特定の遺伝的特性を有する哺乳動物を作製する方法

Country Status (9)

Country Link
US (1) US6492575B1 (enExample)
EP (1) EP0928332B1 (enExample)
JP (2) JP2000516463A (enExample)
AT (1) ATE281516T1 (enExample)
CA (1) CA2263729C (enExample)
DE (2) DE19632532A1 (enExample)
ES (1) ES2231883T3 (enExample)
PT (1) PT928332E (enExample)
WO (1) WO1998006834A1 (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5523226A (en) * 1993-05-14 1996-06-04 Biotechnology Research And Development Corp. Transgenic swine compositions and methods
CN1083687C (zh) * 1999-02-15 2002-05-01 湖南师范大学 四倍体鱼的培育方法
CN1419413A (zh) * 2000-03-28 2003-05-21 路德维格癌症研究所 表达血小板衍生生长因子c(pdgf-c)的非人转基因动物及其应用
US6784336B2 (en) * 2000-09-20 2004-08-31 Whitehead Institute For Biomedical Research Method of producing mutant mice
JP4087338B2 (ja) * 2001-11-15 2008-05-21 キリンファーマ株式会社 キメラ非ヒト動物
JP4364474B2 (ja) 2002-02-15 2009-11-18 大学共同利用機関法人情報・システム研究機構 哺乳動物において機能的なトランスポゾン
US7365182B2 (en) * 2002-05-01 2008-04-29 Michigan State University Plant vernalization independence (VIP) genes, proteins, and methods of use
GB0210539D0 (en) * 2002-05-08 2002-06-19 Univ Edinburgh Control of es cell self renewal and lineage specification, and medium therefor
US7723565B2 (en) * 2004-01-07 2010-05-25 Wisconsin Alumni Research Foundation Vernalization-related molecules and methods for inducibly-conferring epigenetic changes
EP2064325B1 (en) 2006-09-01 2011-12-07 Therapeutic Human Polyclonals, Inc. Enhanced expression of human or humanized immunoglobulin in non-human transgenic animals
JP5624891B2 (ja) * 2007-12-31 2014-11-12 バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated ヒト血液凝固因子を発現するトランスジェニック非ヒト動物
US9587249B2 (en) 2008-10-27 2017-03-07 Baxalta GmbH Models of thrombotic thrombocytopenic purpura and methods of use thereof
US20120178158A1 (en) * 2009-06-23 2012-07-12 The Scripps Research Institute Adult animals generated from induced pluripotent cells
JP2013500743A (ja) 2009-08-04 2013-01-10 バクスター・インターナショナル・インコーポレイテッド Fviiiおよびvwfがノックアウトされた遺伝子導入マウス−血友病aモデル
US10662256B2 (en) 2010-07-26 2020-05-26 Trianni, Inc. Transgenic mammals and methods of use thereof
US10793829B2 (en) 2010-07-26 2020-10-06 Trianni, Inc. Transgenic mammals and methods of use thereof
AU2011286185B2 (en) 2010-07-26 2014-08-14 Trianni, Inc. Transgenic animals and methods of use
WO2015013575A2 (en) * 2013-07-25 2015-01-29 Ingenious Targeting Laboratory, Inc. Knockout mice derived from site specific recombinase
EP3384030A4 (en) 2015-12-03 2019-07-03 Trianni, Inc. IMPROVED IMMUNOGLULINIVITY
JP6929877B2 (ja) 2016-02-04 2021-09-01 トリアニ・インコーポレイテッドTrianni, Inc. 免疫グロブリン産生の増強
MA52431A (fr) * 2018-03-02 2021-01-06 Generation Bio Co Identification et caractérisation de zones de sécurité du génome (gsh) chez les êtres humains et les génomes murins, et compositions de vecteurs viraux et non viraux pour une intégration ciblée au niveau d'un locus gsh identifié
JP7578306B2 (ja) * 2020-03-06 2024-11-06 広州明訊生物科技有限公司 動物の製造方法
WO2022235929A1 (en) 2021-05-05 2022-11-10 Radius Pharmaceuticals, Inc. Animal model having homologous recombination of mouse pth1 receptor
CN115466718B (zh) * 2022-08-09 2023-07-14 广州明迅生物科技有限责任公司 雌性胚胎干细胞及其制备方法和应用
CN118185862B (zh) * 2024-05-16 2024-08-09 中国科学院昆明动物研究所 一种小鼠四倍体器官的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ244306A (en) * 1991-09-30 1995-07-26 Boehringer Ingelheim Int Composition for introducing nucleic acid complexes into eucaryotic cells, complex containing nucleic acid and endosomolytic agent, peptide with endosomolytic domain and nucleic acid binding domain and preparation
DE4228162C1 (de) * 1992-08-25 1994-01-13 Rajewsky Klaus Dr Verfahren zum Ersetzen homologer Genabschnitte aus Säugern in der Keimbahn von nicht-menschlichen Säugern
US5523226A (en) 1993-05-14 1996-06-04 Biotechnology Research And Development Corp. Transgenic swine compositions and methods
US5907080A (en) * 1995-11-30 1999-05-25 Nexia Biotechnologies, Inc. Method for development of transgenic dwarf goats
US6331406B1 (en) 1997-03-31 2001-12-18 The John Hopkins University School Of Medicine Human enbryonic germ cell and methods of use

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