ATE281516T1 - Verfahren zur herstellung von säugetieren mit definierten genetischen eigenschaften - Google Patents

Verfahren zur herstellung von säugetieren mit definierten genetischen eigenschaften

Info

Publication number
ATE281516T1
ATE281516T1 AT97936698T AT97936698T ATE281516T1 AT E281516 T1 ATE281516 T1 AT E281516T1 AT 97936698 T AT97936698 T AT 97936698T AT 97936698 T AT97936698 T AT 97936698T AT E281516 T1 ATE281516 T1 AT E281516T1
Authority
AT
Austria
Prior art keywords
cells
defined genetic
mammals
genetic characteristics
producing mammals
Prior art date
Application number
AT97936698T
Other languages
German (de)
English (en)
Inventor
Erwin Wagner
Zhao-Qi Wang
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Application granted granted Critical
Publication of ATE281516T1 publication Critical patent/ATE281516T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Environmental Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT97936698T 1996-08-13 1997-08-09 Verfahren zur herstellung von säugetieren mit definierten genetischen eigenschaften ATE281516T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19632532A DE19632532A1 (de) 1996-08-13 1996-08-13 Verfahren zur Herstellung von Säugetieren mit definierten genetischen Eigenschaften
PCT/EP1997/004352 WO1998006834A1 (de) 1996-08-13 1997-08-09 Verfahren zur herstellung von säugetieren mit definierten genetischen eigenschaften

Publications (1)

Publication Number Publication Date
ATE281516T1 true ATE281516T1 (de) 2004-11-15

Family

ID=7802466

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97936698T ATE281516T1 (de) 1996-08-13 1997-08-09 Verfahren zur herstellung von säugetieren mit definierten genetischen eigenschaften

Country Status (9)

Country Link
US (1) US6492575B1 (enExample)
EP (1) EP0928332B1 (enExample)
JP (2) JP2000516463A (enExample)
AT (1) ATE281516T1 (enExample)
CA (1) CA2263729C (enExample)
DE (2) DE19632532A1 (enExample)
ES (1) ES2231883T3 (enExample)
PT (1) PT928332E (enExample)
WO (1) WO1998006834A1 (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5523226A (en) * 1993-05-14 1996-06-04 Biotechnology Research And Development Corp. Transgenic swine compositions and methods
CN1083687C (zh) * 1999-02-15 2002-05-01 湖南师范大学 四倍体鱼的培育方法
AU2001249525A1 (en) * 2000-03-28 2001-10-08 Ludwig Institute For Cancer Research Non-human transgenic animals expressing platelet-derived growth factor C (PDGF-C) and uses thereof
US6784336B2 (en) * 2000-09-20 2004-08-31 Whitehead Institute For Biomedical Research Method of producing mutant mice
EP1452093A4 (en) * 2001-11-15 2007-08-15 Kirin Brewery CHIMESE NON-MENTAL ANIMAL
JP4364474B2 (ja) 2002-02-15 2009-11-18 大学共同利用機関法人情報・システム研究機構 哺乳動物において機能的なトランスポゾン
US7365182B2 (en) * 2002-05-01 2008-04-29 Michigan State University Plant vernalization independence (VIP) genes, proteins, and methods of use
GB0210539D0 (en) * 2002-05-08 2002-06-19 Univ Edinburgh Control of es cell self renewal and lineage specification, and medium therefor
US7723565B2 (en) * 2004-01-07 2010-05-25 Wisconsin Alumni Research Foundation Vernalization-related molecules and methods for inducibly-conferring epigenetic changes
ATE536374T1 (de) 2006-09-01 2011-12-15 Therapeutic Human Polyclonals Inc Erhöhte expression von humanem oder humanisiertem immunglobulin bei nicht-humanen transgenen tieren
CA2710567A1 (en) 2007-12-31 2009-07-16 Baxter Healthcare S.A. Transgenic non-human animals expressing human blood clotting factors
NZ609908A (en) * 2008-10-27 2014-07-25 Baxter Int Models of thrombotic thrombocytopenic purpura and methods of use thereof
WO2011005580A2 (en) * 2009-06-23 2011-01-13 The Scripps Research Institute Adult animals generated from induced pluripotent cells
US20110072524A1 (en) 2009-08-04 2011-03-24 Baxter International Inc. Transgenic Mouse Lacking Endogenous FVIII and VWF - A Model of Hemophilia A
US10662256B2 (en) 2010-07-26 2020-05-26 Trianni, Inc. Transgenic mammals and methods of use thereof
RU2580017C2 (ru) 2010-07-26 2016-04-10 Трианни, Инк. Трансгенные животные и способы применения
US10793829B2 (en) 2010-07-26 2020-10-06 Trianni, Inc. Transgenic mammals and methods of use thereof
WO2015013575A2 (en) * 2013-07-25 2015-01-29 Ingenious Targeting Laboratory, Inc. Knockout mice derived from site specific recombinase
WO2017095939A1 (en) 2015-12-03 2017-06-08 Trianni, Inc. Enhanced immunoglobulin diversity
IL260743B2 (en) 2016-02-04 2024-03-01 Trianni Inc Advanced production of antibodies
US20200390072A1 (en) * 2018-03-02 2020-12-17 Generation Bio Co. Identifying and characterizing genomic safe harbors (gsh) in humans and murine genomes, and viral and non-viral vector compositions for targeted integration at an identified gsh loci
EP4144857A4 (en) * 2020-03-06 2024-02-28 Mingceler Biotechnology Co., Ltd. PROCESS FOR PREPARING AN ANIMAL
US20240374761A1 (en) 2021-05-05 2024-11-14 Radius Pharmaceuticals, Inc. Animal model having homologous recombination of mouse pth1 receptor
CN115466718B (zh) * 2022-08-09 2023-07-14 广州明迅生物科技有限责任公司 雌性胚胎干细胞及其制备方法和应用
CN118185862B (zh) * 2024-05-16 2024-08-09 中国科学院昆明动物研究所 一种小鼠四倍体器官的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ244306A (en) * 1991-09-30 1995-07-26 Boehringer Ingelheim Int Composition for introducing nucleic acid complexes into eucaryotic cells, complex containing nucleic acid and endosomolytic agent, peptide with endosomolytic domain and nucleic acid binding domain and preparation
DE4228162C1 (de) * 1992-08-25 1994-01-13 Rajewsky Klaus Dr Verfahren zum Ersetzen homologer Genabschnitte aus Säugern in der Keimbahn von nicht-menschlichen Säugern
US5523226A (en) 1993-05-14 1996-06-04 Biotechnology Research And Development Corp. Transgenic swine compositions and methods
US5907080A (en) * 1995-11-30 1999-05-25 Nexia Biotechnologies, Inc. Method for development of transgenic dwarf goats
US6331406B1 (en) 1997-03-31 2001-12-18 The John Hopkins University School Of Medicine Human enbryonic germ cell and methods of use

Also Published As

Publication number Publication date
CA2263729C (en) 2006-06-27
EP0928332A1 (de) 1999-07-14
ES2231883T3 (es) 2005-05-16
JP2006296440A (ja) 2006-11-02
PT928332E (pt) 2005-01-31
DE19632532A1 (de) 1998-02-19
WO1998006834A1 (de) 1998-02-19
EP0928332B1 (de) 2004-11-03
DE59712068D1 (de) 2004-12-09
CA2263729A1 (en) 1998-02-19
US6492575B1 (en) 2002-12-10
JP4129472B2 (ja) 2008-08-06
US20020178457A1 (en) 2002-11-28
JP2000516463A (ja) 2000-12-12

Similar Documents

Publication Publication Date Title
ATE281516T1 (de) Verfahren zur herstellung von säugetieren mit definierten genetischen eigenschaften
Yoshimizu et al. Germline‐specific expression of the Oct‐4/green fluorescent protein (GFP) transgene in mice
Meissner et al. Mammalian nuclear transfer
JP5686357B2 (ja) ｉＰＳ細胞などの多能性細胞とＢＬＡＳＴＯＣＹＳＴＣＯＭＰＬＥＭＥＮＴＡＴＩＯＮを利用した臓器再生法
IL126416A0 (en) Cultured inner cell mass cell lines derived from ungulate embryos
DE60033663D1 (de) Verfahren zur herstellung einer nicht-differenzierten kultur von vogelzellen mittels primordialer keimzellen
NZ336612A (en) Cloning using donor nuclei from proliferating somatic cells
FI963419A0 (fi) Fibrinogeenin valmistus transgeenisissä eläimissä
EP1017423A4 (en) CLONING OF PIGS USING DONOR CORES FROM DIFFERENTIATED CELLS
ATE332077T1 (de) Transgene mäuse die ein menschliche antikörper exprimieren
TW367365B (en) An improved method for obtaining plant somatic embryos about the somatic embryo suspension cultures and pro-embryogenic mass suspension cultures
DE69832716D1 (de) Herstellung embryonischer vogel keimzellinien durch verlängerte kultivierung von pgcs, verwendung desselben zur klonierung und chimerisierung
CA2361943A1 (en) Genetic modification of somatic cells and uses thereof
Hodges et al. Generation of bovine transgenics using somatic cell nuclear transfer
US20110283374A1 (en) Method for producing heterogenous embryonic chimeric animal using a stem cell
NZ598769A (en) Transgenic chickens
DK0453458T3 (da) Fremgangsmåde til fremstilling af et transgent ikke-menneskeligt dyr ved indføring af exogent DNA i somatiske dyreceller og germdyreceller
Hirabayashi et al. Haploid embryonic stem cell lines derived from androgenetic and parthenogenetic rat blastocysts
Wagner et al. Method for developing transgenic mice
ATE364693T1 (de) Verfahren zur herstellung von nicht-humanen geklonten und transgenen säugetieren
Gardner Pluripotent stem cells from vertebrate embryos: present perspective and future challenges
KR100250599B1 (ko) 에이치3 배아간세포주 및 이를 이용한 유전자이식 생쥐의 제조방법
Matthaei Current developments in genetically manipulated mice
Gardner Pluripotential stem cells from vertebrate embryos: present perspective and future challenges
Gardner Present perspective and future challenges