JP2000516463A - 特定の遺伝的特性を有する哺乳動物を作製する方法 - Google Patents

特定の遺伝的特性を有する哺乳動物を作製する方法

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Publication number
JP2000516463A
JP2000516463A JP10509392A JP50939298A JP2000516463A JP 2000516463 A JP2000516463 A JP 2000516463A JP 10509392 A JP10509392 A JP 10509392A JP 50939298 A JP50939298 A JP 50939298A JP 2000516463 A JP2000516463 A JP 2000516463A
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Japan
Prior art keywords
cells
mice
blastocysts
cell
embryos
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP10509392A
Other languages
English (en)
Japanese (ja)
Other versions
JP2000516463A5 (enExample
Inventor
エルウィン ワーグナー
ツァオ クィ ワン
Original Assignee
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
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Publication date
Application filed by ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング filed Critical ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
Publication of JP2000516463A publication Critical patent/JP2000516463A/ja
Publication of JP2000516463A5 publication Critical patent/JP2000516463A5/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Environmental Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
JP10509392A 1996-08-13 1997-08-09 特定の遺伝的特性を有する哺乳動物を作製する方法 Withdrawn JP2000516463A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19632532.3 1996-08-13
DE19632532A DE19632532A1 (de) 1996-08-13 1996-08-13 Verfahren zur Herstellung von Säugetieren mit definierten genetischen Eigenschaften
PCT/EP1997/004352 WO1998006834A1 (de) 1996-08-13 1997-08-09 Verfahren zur herstellung von säugetieren mit definierten genetischen eigenschaften

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2006218386A Division JP4129472B2 (ja) 1996-08-13 2006-08-10 特定の遺伝的特性を有する哺乳動物を作製する方法

Publications (2)

Publication Number Publication Date
JP2000516463A true JP2000516463A (ja) 2000-12-12
JP2000516463A5 JP2000516463A5 (enExample) 2005-04-07

Family

ID=7802466

Family Applications (2)

Application Number Title Priority Date Filing Date
JP10509392A Withdrawn JP2000516463A (ja) 1996-08-13 1997-08-09 特定の遺伝的特性を有する哺乳動物を作製する方法
JP2006218386A Expired - Lifetime JP4129472B2 (ja) 1996-08-13 2006-08-10 特定の遺伝的特性を有する哺乳動物を作製する方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2006218386A Expired - Lifetime JP4129472B2 (ja) 1996-08-13 2006-08-10 特定の遺伝的特性を有する哺乳動物を作製する方法

Country Status (9)

Country Link
US (1) US6492575B1 (enExample)
EP (1) EP0928332B1 (enExample)
JP (2) JP2000516463A (enExample)
AT (1) ATE281516T1 (enExample)
CA (1) CA2263729C (enExample)
DE (2) DE19632532A1 (enExample)
ES (1) ES2231883T3 (enExample)
PT (1) PT928332E (enExample)
WO (1) WO1998006834A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7883890B2 (en) 2002-02-15 2011-02-08 Research Organization Of Information And Systems Transposon transfer factor functioned in mammal

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5523226A (en) * 1993-05-14 1996-06-04 Biotechnology Research And Development Corp. Transgenic swine compositions and methods
CN1083687C (zh) * 1999-02-15 2002-05-01 湖南师范大学 四倍体鱼的培育方法
JP2003533675A (ja) * 2000-03-28 2003-11-11 ルードヴィッヒ インスティテュート フォー キャンサー リサーチ 血小板由来成長因子ｃ（ｐｄｇｆ−ｃ）を発現する非ヒトトランスジェニック動物およびそれらの使用
US6784336B2 (en) 2000-09-20 2004-08-31 Whitehead Institute For Biomedical Research Method of producing mutant mice
JP4087338B2 (ja) * 2001-11-15 2008-05-21 キリンファーマ株式会社 キメラ非ヒト動物
US7365182B2 (en) * 2002-05-01 2008-04-29 Michigan State University Plant vernalization independence (VIP) genes, proteins, and methods of use
GB0210539D0 (en) * 2002-05-08 2002-06-19 Univ Edinburgh Control of es cell self renewal and lineage specification, and medium therefor
US7723565B2 (en) * 2004-01-07 2010-05-25 Wisconsin Alumni Research Foundation Vernalization-related molecules and methods for inducibly-conferring epigenetic changes
EP2064325B1 (en) 2006-09-01 2011-12-07 Therapeutic Human Polyclonals, Inc. Enhanced expression of human or humanized immunoglobulin in non-human transgenic animals
TWI492951B (zh) 2007-12-31 2015-07-21 Baxter Int 表現人類凝血因子的基因轉殖非人類動物及其用途
NZ592905A (en) 2008-10-27 2012-11-30 Baxter Int Models of thrombotic thrombocytopenic purpura and methods of use thereof
US20120178158A1 (en) * 2009-06-23 2012-07-12 The Scripps Research Institute Adult animals generated from induced pluripotent cells
US20110072524A1 (en) 2009-08-04 2011-03-24 Baxter International Inc. Transgenic Mouse Lacking Endogenous FVIII and VWF - A Model of Hemophilia A
CN103025884B (zh) 2010-07-26 2015-11-25 特里安尼公司 转基因动物和使用方法
US10662256B2 (en) 2010-07-26 2020-05-26 Trianni, Inc. Transgenic mammals and methods of use thereof
US10793829B2 (en) 2010-07-26 2020-10-06 Trianni, Inc. Transgenic mammals and methods of use thereof
WO2015013575A2 (en) * 2013-07-25 2015-01-29 Ingenious Targeting Laboratory, Inc. Knockout mice derived from site specific recombinase
EP3384030A4 (en) 2015-12-03 2019-07-03 Trianni, Inc. IMPROVED IMMUNOGLULINIVITY
EP4414484A3 (en) 2016-02-04 2025-01-15 Trianni, Inc. Enhanced production of immunoglobulins
CA3092832A1 (en) * 2018-03-02 2019-09-06 Generation Bio Co. Identifying and characterizing genomic safe harbors (gsh) in humans and murine genomes, and viral and non-viral vector compositions for targeted integration at an identified gsh loci
WO2021174742A1 (zh) * 2020-03-06 2021-09-10 生物岛实验室 一种动物的制备方法
US20240374761A1 (en) 2021-05-05 2024-11-14 Radius Pharmaceuticals, Inc. Animal model having homologous recombination of mouse pth1 receptor
CN115466718B (zh) * 2022-08-09 2023-07-14 广州明迅生物科技有限责任公司 雌性胚胎干细胞及其制备方法和应用
CN118185862B (zh) * 2024-05-16 2024-08-09 中国科学院昆明动物研究所 一种小鼠四倍体器官的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ244306A (en) * 1991-09-30 1995-07-26 Boehringer Ingelheim Int Composition for introducing nucleic acid complexes into eucaryotic cells, complex containing nucleic acid and endosomolytic agent, peptide with endosomolytic domain and nucleic acid binding domain and preparation
DE4228162C1 (de) * 1992-08-25 1994-01-13 Rajewsky Klaus Dr Verfahren zum Ersetzen homologer Genabschnitte aus Säugern in der Keimbahn von nicht-menschlichen Säugern
US5523226A (en) * 1993-05-14 1996-06-04 Biotechnology Research And Development Corp. Transgenic swine compositions and methods
US5907080A (en) * 1995-11-30 1999-05-25 Nexia Biotechnologies, Inc. Method for development of transgenic dwarf goats
US6331406B1 (en) 1997-03-31 2001-12-18 The John Hopkins University School Of Medicine Human enbryonic germ cell and methods of use

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7883890B2 (en) 2002-02-15 2011-02-08 Research Organization Of Information And Systems Transposon transfer factor functioned in mammal

Also Published As

Publication number Publication date
US6492575B1 (en) 2002-12-10
DE19632532A1 (de) 1998-02-19
WO1998006834A1 (de) 1998-02-19
CA2263729C (en) 2006-06-27
PT928332E (pt) 2005-01-31
EP0928332B1 (de) 2004-11-03
JP2006296440A (ja) 2006-11-02
ES2231883T3 (es) 2005-05-16
ATE281516T1 (de) 2004-11-15
DE59712068D1 (de) 2004-12-09
CA2263729A1 (en) 1998-02-19
US20020178457A1 (en) 2002-11-28
EP0928332A1 (de) 1999-07-14
JP4129472B2 (ja) 2008-08-06

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