JP2000506861A5 - - Google Patents

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Publication number
JP2000506861A5
JP2000506861A5 JP1997532601A JP53260197A JP2000506861A5 JP 2000506861 A5 JP2000506861 A5 JP 2000506861A5 JP 1997532601 A JP1997532601 A JP 1997532601A JP 53260197 A JP53260197 A JP 53260197A JP 2000506861 A5 JP2000506861 A5 JP 2000506861A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1997532601A
Other languages
English (en)
Japanese (ja)
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JP2000506861A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1997/002295 external-priority patent/WO1997033858A1/en
Publication of JP2000506861A publication Critical patent/JP2000506861A/ja
Publication of JP2000506861A5 publication Critical patent/JP2000506861A5/ja
Ceased legal-status Critical Current

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JP9532601A 1996-03-14 1997-02-18 医薬としての新規な置換環状アミノ酸 Ceased JP2000506861A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1343296P 1996-03-14 1996-03-14
US60/013,432 1996-03-14
PCT/US1997/002295 WO1997033858A1 (en) 1996-03-14 1997-02-18 Novel substituted cyclic amino acids as pharmaceutical agents

Publications (2)

Publication Number Publication Date
JP2000506861A JP2000506861A (ja) 2000-06-06
JP2000506861A5 true JP2000506861A5 (enExample) 2004-11-25

Family

ID=21759938

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9532601A Ceased JP2000506861A (ja) 1996-03-14 1997-02-18 医薬としての新規な置換環状アミノ酸

Country Status (29)

Country Link
US (1) US6103932A (enExample)
EP (1) EP0888286B1 (enExample)
JP (1) JP2000506861A (enExample)
KR (1) KR100512506B1 (enExample)
AT (1) ATE207878T1 (enExample)
AU (1) AU734173B2 (enExample)
BG (1) BG63662B1 (enExample)
BR (1) BR9708200A (enExample)
CA (1) CA2244912C (enExample)
CZ (1) CZ293759B6 (enExample)
DE (1) DE69707842T2 (enExample)
DK (2) DK0888285T3 (enExample)
EA (1) EA002765B1 (enExample)
EE (1) EE9800309A (enExample)
ES (1) ES2167717T3 (enExample)
GE (1) GEP20012413B (enExample)
HU (1) HU224720B1 (enExample)
IL (1) IL125544A (enExample)
IS (1) IS1990B (enExample)
MX (1) MX9806069A (enExample)
NO (1) NO984205L (enExample)
NZ (1) NZ331143A (enExample)
PL (1) PL185991B1 (enExample)
PT (1) PT888286E (enExample)
SK (1) SK283295B6 (enExample)
TR (1) TR199801807T2 (enExample)
UA (1) UA49011C2 (enExample)
WO (1) WO1997033858A1 (enExample)
ZA (1) ZA972200B (enExample)

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JP2003528148A (ja) * 2000-03-28 2003-09-24 デロレンゾ、ロバート・ジェイ 損傷に際して神経細胞中に形成される新規カルシウム損傷電流の阻害は神経細胞死を抑制する
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US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
WO2002100344A2 (en) * 2001-06-11 2002-12-19 Xenoport, Inc. Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7232924B2 (en) * 2001-06-11 2007-06-19 Xenoport, Inc. Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
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US7186855B2 (en) * 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
JP2005518411A (ja) * 2002-01-16 2005-06-23 エンド ファーマシューティカルズ インコーポレーテッド 中枢神経系の障害を治療する製薬組成物及び方法
AU2002316231A1 (en) * 2002-02-19 2003-09-29 Xenoport, Inc. Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof
AU2003222033A1 (en) 2002-03-20 2003-10-08 Xenoport Cyclic 1-(acyloxy)-alkyl prodrugs of gaba analogs, compositions and uses thereof
EP1549323A2 (en) * 2002-05-07 2005-07-06 A & D Bioscience, Inc. Conjugates comprising central nervous system active drug
AU2003243180A1 (en) * 2002-05-17 2003-12-12 Xenoport, Inc. Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
US7060727B2 (en) * 2002-12-11 2006-06-13 Xenoport, Inc. Prodrugs of fused GABA analogs, pharmaceutical compositions and uses thereof
US20040162351A1 (en) * 2002-12-11 2004-08-19 Gallop Mark A. Orally administered dosage forms of fused GABA analog prodrugs having reduced toxicity
NZ539972A (en) 2002-12-13 2008-05-30 Warner Lambert Co Alpha-2-delta ligand to treat lower urinary tract symptoms
CA2451267A1 (en) 2002-12-13 2004-06-13 Warner-Lambert Company Llc Pharmaceutical uses for alpha2delta ligands
GB0301143D0 (en) * 2003-01-17 2003-02-19 Amedis Pharm Ltd Compounds and their use
JP2006522146A (ja) * 2003-03-31 2006-09-28 ゼノポート,インコーポレイティド Gaba類似体のプロドラッグを使用するのぼせの治療または予防
CA2537837A1 (en) * 2003-09-11 2005-03-24 Xenoport, Inc. Treating and/or preventing urinary incontinence using prodrugs of gaba analogs
EP2156863A3 (en) 2003-09-12 2011-01-12 Pfizer Limited Combinations comprising alpha-2-delta ligands and serotonin / noradrenaline reuptake inhibitors
CA2538802C (en) * 2003-09-17 2015-01-27 Xenoport, Inc. Treating or preventing restless legs syndrome using prodrugs of gaba analogs
PT1677767E (pt) * 2003-10-14 2011-10-13 Xenoport Inc Forma cristalina de análogo de ácido gama-aminobutírico
JP5646126B2 (ja) 2003-12-11 2014-12-24 サノビオン ファーマシューティカルズ インクSunovion Pharmaceuticals Inc. 鎮静剤と神経伝達物質調節剤の併用、および睡眠の質の向上方法および鬱の治療方法
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PL2125021T3 (pl) 2006-12-22 2011-10-31 Recordati Ireland Ltd Leczenie skojarzone zaburzeń w obrębie dolnych dróg moczowych z zastosowaniem ligandów α2δ i przeciwzapalnych leków niesterydowych (NSAIDs)
WO2008103319A2 (en) 2007-02-16 2008-08-28 Ark Diagnostics, Inc. Compounds and methods for use in detecting gabapentin
US20090041806A1 (en) * 2007-06-15 2009-02-12 Xenoport, Inc. Use of prodrugs of gaba analogs, antispasticity agents, and prodrugs of gaba b receptor agonists for treating spasticity
US20090118365A1 (en) * 2007-11-06 2009-05-07 Xenoport, Inc Use of Prodrugs of GABA B Agonists for Treating Neuropathic and Musculoskeletal Pain
US7872046B2 (en) 2008-01-25 2011-01-18 Xenoport, Inc. Crystalline form of a (3S)-aminomethyl-5-methyl-hexanoic acid prodrug and methods of use
WO2009094577A2 (en) 2008-01-25 2009-07-30 Xenoport, Inc. Mesophasic forms of (3s)-aminomethyl-5-methyl-hexanoic acid prodrugs and methods of use
EP2250143B1 (en) * 2008-01-25 2016-04-20 XenoPort, Inc. Method for the enzymatic kinetic resolution of acyloxyalkyl thiocarbonates used for the synthesis of acyloxyalkyl carbamates
EP3075722A1 (en) 2008-10-08 2016-10-05 Xgene Pharmaceutical Inc Gaba conjugates and methods of use thereof
WO2010048423A1 (en) 2008-10-24 2010-04-29 Ark Diagnostics, Inc. Levetiracetam immunoassays
WO2010099200A1 (en) * 2009-02-24 2010-09-02 Nektar Therapeutics Oligomer-amino acid conjugates
US20110124705A1 (en) * 2009-11-24 2011-05-26 Xenoport, Inc. Prodrugs of alpha-2-delta ligands, pharmaceutical compositions and uses thereof
US20110130454A1 (en) * 2009-11-24 2011-06-02 Xenoport, Inc. Prodrugs of gamma-amino acid, alpha-2-delta ligands, pharmaceutical compositions and uses thereof
US9066853B2 (en) 2013-01-15 2015-06-30 Warsaw Orthopedic, Inc. Clonidine compounds in a biodegradable fiber
US9970929B2 (en) 2013-01-18 2018-05-15 Ark Diagnostics, Inc. Voriconazole immunoassays
HUE047629T2 (hu) 2013-01-28 2020-05-28 Lopez Hector L Eljárások ß-alanin tolerancia, farmakodinamika és hatékonyság javítására és azok alkalmazása
ES2674704T3 (es) 2013-02-13 2018-07-03 Ark Diagnostics, Inc. Inmunoensayos de posaconazol
US20210221768A1 (en) 2018-05-14 2021-07-22 Xgene Pharmaceutical Inc. Crystalline forms of 1-(acyloxy)-alkyl carbamate drug conjugates of naproxen and pregabalin

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