JP2000512648A - ピペリジン酢酸誘導体および血栓障害の治療におけるそれらの使用 - Google Patents

ピペリジン酢酸誘導体および血栓障害の治療におけるそれらの使用

Info

Publication number
JP2000512648A
JP2000512648A JP10502284A JP50228498A JP2000512648A JP 2000512648 A JP2000512648 A JP 2000512648A JP 10502284 A JP10502284 A JP 10502284A JP 50228498 A JP50228498 A JP 50228498A JP 2000512648 A JP2000512648 A JP 2000512648A
Authority
JP
Japan
Prior art keywords
piperidin
formula
compound
indazol
acetic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10502284A
Other languages
English (en)
Japanese (ja)
Inventor
デイビッド、ジョージ、アラン
コリン、デイビッド、エルドレッド
ブライアン、デイビッド、ジュドキンス
ウイリアム、レオナルド、ミッチェル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9613095.0A external-priority patent/GB9613095D0/en
Priority claimed from GBGB9613018.2A external-priority patent/GB9613018D0/en
Priority claimed from GBGB9613017.4A external-priority patent/GB9613017D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of JP2000512648A publication Critical patent/JP2000512648A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP10502284A 1996-06-21 1997-06-19 ピペリジン酢酸誘導体および血栓障害の治療におけるそれらの使用 Pending JP2000512648A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB9613018.2 1996-06-21
GB9613095.0 1996-06-21
GBGB9613095.0A GB9613095D0 (en) 1996-06-21 1996-06-21 Therapeutic piperidines
GB9613017.4 1996-06-21
GBGB9613018.2A GB9613018D0 (en) 1996-06-21 1996-06-21 Therapeutic indazoles
GBGB9613017.4A GB9613017D0 (en) 1996-06-21 1996-06-21 Therapeutic compounds
PCT/EP1997/003196 WO1997049699A1 (en) 1996-06-21 1997-06-19 Piperidine acetic acid derivatives and their use in the treatment of thrombotic disorders

Publications (1)

Publication Number Publication Date
JP2000512648A true JP2000512648A (ja) 2000-09-26

Family

ID=27268341

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10502284A Pending JP2000512648A (ja) 1996-06-21 1997-06-19 ピペリジン酢酸誘導体および血栓障害の治療におけるそれらの使用

Country Status (17)

Country Link
EP (1) EP0912555A1 (xx)
JP (1) JP2000512648A (xx)
KR (1) KR20000022041A (xx)
AP (1) AP9801417A0 (xx)
AR (1) AR008245A1 (xx)
AU (1) AU3261197A (xx)
BR (1) BR9709930A (xx)
CA (1) CA2258753A1 (xx)
CZ (1) CZ424698A3 (xx)
EA (1) EA199801015A1 (xx)
ID (1) ID17052A (xx)
IL (1) IL127464A0 (xx)
IS (1) IS4924A (xx)
NO (1) NO985974L (xx)
PL (1) PL330797A1 (xx)
TR (1) TR199802665T2 (xx)
WO (1) WO1997049699A1 (xx)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005536520A (ja) * 2002-07-18 2005-12-02 ワイス ５−ヒドロキシトリプタミン−６リガンドとしての１−（ヘテロサイクリルアルキル）−３−スルホニルインドールまたはインダゾール誘導体
JP2006518385A (ja) * 2003-02-14 2006-08-10 ワイス ５−ヒドロキシトリプタミン−６リガンドとしてのヘテロサイクリル−３−スルホニルインダゾール

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1401831A1 (en) 2001-07-03 2004-03-31 Chiron Corporation Indazole benzimidazole compounds as tyrosine and serine/threonine kinase inhibitors
US7642278B2 (en) 2001-07-03 2010-01-05 Novartis Vaccines And Diagnostics, Inc. Indazole benzimidazole compounds
EP2001865A1 (en) 2006-04-05 2008-12-17 Wyeth a Corporation of the State of Delaware Sulfonyl-3-heterocyclylindazole derivatives as 5-hydroxytryptamine-6 ligands
EP2118062A1 (en) 2007-01-10 2009-11-18 F. Hoffmann-Roche AG Sulfonamide derivatives as chymase inhibitors
CN113655155A (zh) * 2021-07-28 2021-11-16 任贤金 一种测定sph3127有关物质的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4124942A1 (de) * 1991-07-27 1993-01-28 Thomae Gmbh Dr K 5-gliedrige heterocyclen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
AU2915892A (en) * 1991-11-14 1993-06-15 Glaxo Group Limited Piperidine acetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation
GB9208740D0 (en) * 1992-04-23 1992-06-10 Glaxo Group Ltd Chemical compounds

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005536520A (ja) * 2002-07-18 2005-12-02 ワイス ５−ヒドロキシトリプタミン−６リガンドとしての１−（ヘテロサイクリルアルキル）−３−スルホニルインドールまたはインダゾール誘導体
JP2006518385A (ja) * 2003-02-14 2006-08-10 ワイス ５−ヒドロキシトリプタミン−６リガンドとしてのヘテロサイクリル−３−スルホニルインダゾール

Also Published As

Publication number Publication date
IS4924A (is) 1998-12-15
AR008245A1 (es) 1999-12-29
WO1997049699A1 (en) 1997-12-31
BR9709930A (pt) 1999-08-10
NO985974D0 (no) 1998-12-18
KR20000022041A (ko) 2000-04-25
EA199801015A1 (ru) 1999-08-26
TR199802665T2 (xx) 1999-03-22
ID17052A (id) 1997-12-04
EP0912555A1 (en) 1999-05-06
AU3261197A (en) 1998-01-14
IL127464A0 (en) 1999-10-28
CA2258753A1 (en) 1997-12-31
AP9801417A0 (en) 1998-12-31
CZ424698A3 (cs) 1999-05-12
PL330797A1 (en) 1999-06-07
NO985974L (no) 1999-02-17

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