JP2000510148A - 7―o―メトキシメチルパクリタキセル - Google Patents

7―o―メトキシメチルパクリタキセル

Info

Publication number
JP2000510148A
JP2000510148A JP09541052A JP54105297A JP2000510148A JP 2000510148 A JP2000510148 A JP 2000510148A JP 09541052 A JP09541052 A JP 09541052A JP 54105297 A JP54105297 A JP 54105297A JP 2000510148 A JP2000510148 A JP 2000510148A
Authority
JP
Japan
Prior art keywords
paclitaxel
compound
methoxymethyl
ethyl acetate
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP09541052A
Other languages
English (en)
Japanese (ja)
Inventor
マーク ディー ウィットマン
Original Assignee
ブリストル―マイヤーズ スクイブ カンパニー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ブリストル―マイヤーズ スクイブ カンパニー filed Critical ブリストル―マイヤーズ スクイブ カンパニー
Publication of JP2000510148A publication Critical patent/JP2000510148A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
JP09541052A 1996-05-16 1997-05-08 7―o―メトキシメチルパクリタキセル Pending JP2000510148A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1791996P 1996-05-16 1996-05-16
US60/017,919 1996-05-16
PCT/US1997/008079 WO1997042948A1 (en) 1996-05-16 1997-05-08 7-o-methoxymethyl paclitaxel

Publications (1)

Publication Number Publication Date
JP2000510148A true JP2000510148A (ja) 2000-08-08

Family

ID=21785279

Family Applications (1)

Application Number Title Priority Date Filing Date
JP09541052A Pending JP2000510148A (ja) 1996-05-16 1997-05-08 7―o―メトキシメチルパクリタキセル

Country Status (5)

Country Link
EP (1) EP0906095A1 (enrdf_load_stackoverflow)
JP (1) JP2000510148A (enrdf_load_stackoverflow)
AU (1) AU706955B2 (enrdf_load_stackoverflow)
CA (1) CA2253443A1 (enrdf_load_stackoverflow)
WO (1) WO1997042948A1 (enrdf_load_stackoverflow)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4960790A (en) * 1989-03-09 1990-10-02 University Of Kansas Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof
US5646176A (en) * 1992-12-24 1997-07-08 Bristol-Myers Squibb Company Phosphonooxymethyl ethers of taxane derivatives
CA2191224A1 (en) * 1994-06-28 1996-01-11 Pharmacia & Upjohn Company 7-ether-taxol analogs, antineoplastic use and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
AU706955B2 (en) 1999-07-01
EP0906095A4 (enrdf_load_stackoverflow) 1999-05-12
AU3124097A (en) 1997-12-05
CA2253443A1 (en) 1997-11-20
WO1997042948A1 (en) 1997-11-20
EP0906095A1 (en) 1999-04-07

Similar Documents

Publication Publication Date Title
JP4554081B2 (ja) ヒンダードアルコールまたはフェノールの水溶性プロドラッグ
JP2001521493A (ja) 6−ハロ−又はニトレート置換パクリタクセル
WO1994004541A2 (en) Protein kinase inhibitors and related compounds combined with taxol
EP1451168A2 (en) Paclitaxel solvates
DE69622933T2 (de) Prodrugs von Paclitaxel-Derivaten
CN106916177B (zh) 一种氘代的二肽硼酸或其酯类化合物及其合成方法与用途
JPH09500138A (ja) タキソール誘導体
AU706155B2 (en) 7-deoxy-6-substituted paclitaxels
US5840929A (en) C4 methoxy ether derivatives of paclitaxel
JPH09511761A (ja) 抗癌−、抗ウィルス−および植物生長抑制作用をもつ治療用カシノイド製剤
CN102040569B (zh) 类胡萝卜素衍生物及其制备方法和应用
CA2328771A1 (en) 2-aroyl-4-acyl paclitaxel (taxol) analogs
JP2000510148A (ja) 7―o―メトキシメチルパクリタキセル
JPH10502088A (ja) ブレフェルジンaの新しい誘導体およびがん治療におけるそれらの有用性
CN103183722A (zh) 一种乙二醛酶ⅰ抑制剂及其制备方法和医药用途
JP2002535410A (ja) 高められたバイオアベイラビリティーを有するヘスペレチンプロフォーム
JP2001513778A (ja) 7−メチルチオオキソメチルおよび7−メチルチオジオキソメチルパクリタクセル
EP0394135A1 (fr) Noveaux dérivés macrolides, leur procédé de préparation et leur compositions pharmaceutiques qui les contiennent
JP2021527116A (ja) 選択的a2a受容体アンタゴニスト
CN1059896C (zh) 肿瘤逆转剂组成物及其制备方法
WO1999032109A1 (en) 7-deoxy-6-nitrogen substituted paclitaxels
KR0171692B1 (ko) 크로몬 유도체 및 그의 제조방법
RU2200157C2 (ru) Пиридинкарбоксамидины, способ их получения и фармацевтическая композиция на их основе
CA2968483A1 (fr) Derives hydroxybisphosphoniques hydrosolubles de la doxorubicine
CN120248312A (zh) 一种聚合物前药及其载tpp-dox纳米胶束的制备方法与应用