JOP20200101B1 - تخليق مشتقات إستر بورونات واستخداماتها - Google Patents
تخليق مشتقات إستر بورونات واستخداماتهاInfo
- Publication number
- JOP20200101B1 JOP20200101B1 JOJO/P/2020/0101A JOP20200101A JOP20200101B1 JO P20200101 B1 JOP20200101 B1 JO P20200101B1 JO P20200101 A JOP20200101 A JO P20200101A JO P20200101 B1 JOP20200101 B1 JO P20200101B1
- Authority
- JO
- Jordan
- Prior art keywords
- synthesis
- ester derivatives
- boronate ester
- disclosure
- formula
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
- B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
- B01J23/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
- B01J23/46—Ruthenium, rhodium, osmium or iridium
- B01J23/462—Ruthenium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/675—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/04—Esters of boric acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/002—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P9/00—Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Materials Engineering (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Catalysts (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762580343P | 2017-11-01 | 2017-11-01 | |
| PCT/US2018/058143 WO2019089542A1 (en) | 2017-11-01 | 2018-10-30 | Synthesis of boronate ester derivatives and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JOP20200101A1 JOP20200101A1 (ar) | 2022-10-30 |
| JOP20200101B1 true JOP20200101B1 (ar) | 2024-12-22 |
Family
ID=66245250
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JOJO/P/2020/0101A JOP20200101B1 (ar) | 2017-11-01 | 2020-05-06 | تخليق مشتقات إستر بورونات واستخداماتها |
| JOJO/P/2024/0234A JOP20240234A1 (ar) | 2017-11-01 | 2024-10-20 | تخليق مشتقات إستر بورونات واستخداماتها |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JOJO/P/2024/0234A JOP20240234A1 (ar) | 2017-11-01 | 2024-10-20 | تخليق مشتقات إستر بورونات واستخداماتها |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US11999757B2 (https=) |
| EP (1) | EP3704130A4 (https=) |
| JP (1) | JP7480050B2 (https=) |
| KR (1) | KR20200076730A (https=) |
| CN (2) | CN111556872B (https=) |
| AU (1) | AU2018360502B2 (https=) |
| CA (1) | CA3080763A1 (https=) |
| CL (1) | CL2020001143A1 (https=) |
| CO (1) | CO2020006299A2 (https=) |
| JO (2) | JOP20200101B1 (https=) |
| MX (2) | MX2020004425A (https=) |
| PH (1) | PH12020550544A1 (https=) |
| SG (1) | SG11202003762VA (https=) |
| WO (1) | WO2019089542A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111556872B (zh) | 2017-11-01 | 2024-05-10 | 梅琳塔治疗公司 | 硼酸酯衍生物的合成及其用途 |
| CN116789689B (zh) * | 2023-06-21 | 2026-03-20 | 清华大学 | 硼代萘系化合物及其制备方法和应用 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4783443A (en) | 1986-03-03 | 1988-11-08 | The University Of Chicago | Amino acyl cephalosporin derivatives |
| JP2852545B2 (ja) | 1989-11-14 | 1999-02-03 | チッソ株式会社 | 複数の不斉点を持つ光学活性化合物および製造法 |
| CA2165996C (en) | 1995-12-22 | 2002-01-29 | Murray Douglas Bailey | Stereoselective preparation of 2-substituted succinic derivatives |
| FR2745288B1 (fr) | 1996-02-27 | 1998-04-17 | Adir | Nouveaux derives de l'acide boronique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| DE19917979A1 (de) | 1999-04-21 | 2000-10-26 | Clariant Gmbh | Verfahren zur Herstellung von substituierten Phenyl-boronsäuren |
| AU5104300A (en) | 1999-06-04 | 2000-12-28 | Kaneka Corporation | Processes for the preparation of 5-hydroxy-3-oxopentanoic acid derivatives |
| DE10032017A1 (de) | 2000-07-01 | 2002-01-10 | Clariant Gmbh | Verfahren zur Herstellung hochreiner Formylphenylboronsäuren |
| DE10112401A1 (de) * | 2001-03-13 | 2002-09-19 | Degussa | Alkohol-Dehydrogenase und deren Verwendung |
| DE10119274A1 (de) * | 2001-04-20 | 2002-10-31 | Juelich Enzyme Products Gmbh | Enzymatisches Verfahren zur enantioselektiven Reduktion von Ketoverbindungen |
| JP4824874B2 (ja) * | 2001-07-19 | 2011-11-30 | 高砂香料工業株式会社 | 光学活性γ−ブチロラクトンの製造方法 |
| ES2544579T3 (es) * | 2002-07-30 | 2015-09-01 | Takasago International Corporation | Procedimiento de producción de un beta-aminoácido ópticamente activo |
| TWI372725B (en) | 2004-01-30 | 2012-09-21 | Semequip Inc | Methods of synthesis of isotopically enriched borohydride and methods of synthesis of isotopically enriched boranes |
| DE102004022397A1 (de) * | 2004-05-06 | 2005-12-01 | Consortium für elektrochemische Industrie GmbH | Chirale C2-symmetrische Biphenyle, deren Herstellung sowie Metallkomplexe enthaltend diese Liganden und deren Verwendung als Katalysatoren in chirogenen Synthesen |
| WO2007034909A1 (ja) * | 2005-09-22 | 2007-03-29 | Kaneka Corporation | （３ｒ，５ｒ）－７－アミノ－３，５－ジヒドロキシヘプタン酸誘導体の製造法 |
| GB2474687A (en) | 2009-10-23 | 2011-04-27 | Phoenix Chemicals Ltd | A continuous process for the production of (R)-6-cyano-5-hydroxy-3-oxo-hexanoic acid tert-butyl ester (and derivatives) |
| CA2807546C (en) | 2010-08-10 | 2022-08-23 | Rempex Pharmaceuticals, Inc. | Cyclic boronic acid ester derivatives and therapeutic uses thereof |
| WO2013056163A1 (en) | 2011-10-14 | 2013-04-18 | The Regents Of The University Of California | Beta-lactamase inhibitors |
| EP2814483A2 (en) * | 2012-02-15 | 2014-12-24 | Rempex Pharmaceuticals, Inc. | Methods of treating bacterial infections |
| CN104395326B (zh) | 2012-08-20 | 2017-04-05 | 玛耐科股份有限公司 | 二取代硼酸衍生物的制造方法和新型二取代硼酸衍生物 |
| CN102965403A (zh) | 2012-11-19 | 2013-03-13 | 苏州汉酶生物技术有限公司 | (3r,5s)-6-氯-3,5-二羟基己酸叔丁酯的生物制备方法 |
| AU2013355110B2 (en) * | 2012-12-07 | 2017-11-09 | VenatoRx Pharmaceuticals, Inc. | Beta-lactamase inhibitors |
| PT3369724T (pt) | 2013-11-05 | 2021-02-10 | Bracco Imaging Spa | Processo para a preparação de iopamidol |
| ES2750805T3 (es) * | 2014-05-05 | 2020-03-27 | Rempex Pharmaceuticals Inc | Síntesis de sales de boronato y usos de las mismas |
| CN111556872B (zh) | 2017-11-01 | 2024-05-10 | 梅琳塔治疗公司 | 硼酸酯衍生物的合成及其用途 |
-
2018
- 2018-10-30 CN CN201880079247.3A patent/CN111556872B/zh active Active
- 2018-10-30 CA CA3080763A patent/CA3080763A1/en active Pending
- 2018-10-30 AU AU2018360502A patent/AU2018360502B2/en active Active
- 2018-10-30 WO PCT/US2018/058143 patent/WO2019089542A1/en not_active Ceased
- 2018-10-30 US US16/760,369 patent/US11999757B2/en active Active
- 2018-10-30 MX MX2020004425A patent/MX2020004425A/es unknown
- 2018-10-30 EP EP18874877.6A patent/EP3704130A4/en active Pending
- 2018-10-30 CN CN202410485244.7A patent/CN118388347A/zh active Pending
- 2018-10-30 KR KR1020207015638A patent/KR20200076730A/ko not_active Ceased
- 2018-10-30 SG SG11202003762VA patent/SG11202003762VA/en unknown
- 2018-10-30 JP JP2020543266A patent/JP7480050B2/ja active Active
- 2018-10-31 US US16/176,302 patent/US20190127396A1/en not_active Abandoned
-
2020
- 2020-04-30 CL CL2020001143A patent/CL2020001143A1/es unknown
- 2020-05-01 PH PH12020550544A patent/PH12020550544A1/en unknown
- 2020-05-06 JO JOJO/P/2020/0101A patent/JOP20200101B1/ar active
- 2020-05-26 CO CONC2020/0006299A patent/CO2020006299A2/es unknown
- 2020-07-13 MX MX2023000529A patent/MX2023000529A/es unknown
-
2024
- 2024-04-04 US US18/627,105 patent/US20240279248A1/en active Pending
- 2024-10-20 JO JOJO/P/2024/0234A patent/JOP20240234A1/ar unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SG11202003762VA (en) | 2020-05-28 |
| US20190127396A1 (en) | 2019-05-02 |
| CA3080763A1 (en) | 2019-05-09 |
| US11999757B2 (en) | 2024-06-04 |
| EP3704130A1 (en) | 2020-09-09 |
| WO2019089542A1 (en) | 2019-05-09 |
| MX2020004425A (es) | 2020-08-06 |
| AU2018360502B2 (en) | 2024-05-02 |
| MX2023000529A (es) | 2023-02-13 |
| JP2021501205A (ja) | 2021-01-14 |
| KR20200076730A (ko) | 2020-06-29 |
| CN118388347A (zh) | 2024-07-26 |
| US20200308197A1 (en) | 2020-10-01 |
| JOP20200101A1 (ar) | 2022-10-30 |
| JP7480050B2 (ja) | 2024-05-09 |
| JOP20240234A1 (ar) | 2024-10-20 |
| US20240279248A1 (en) | 2024-08-22 |
| CN111556872B (zh) | 2024-05-10 |
| EP3704130A4 (en) | 2021-07-07 |
| CN111556872A (zh) | 2020-08-18 |
| CL2020001143A1 (es) | 2020-10-30 |
| CO2020006299A2 (es) | 2020-06-09 |
| AU2018360502A1 (en) | 2020-06-04 |
| BR112020008498A2 (pt) | 2020-10-20 |
| PH12020550544A1 (en) | 2021-03-22 |
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