CO2020006299A2 - Síntesis de derivados de éster boronato y usos de estos - Google Patents
Síntesis de derivados de éster boronato y usos de estosInfo
- Publication number
- CO2020006299A2 CO2020006299A2 CONC2020/0006299A CO2020006299A CO2020006299A2 CO 2020006299 A2 CO2020006299 A2 CO 2020006299A2 CO 2020006299 A CO2020006299 A CO 2020006299A CO 2020006299 A2 CO2020006299 A2 CO 2020006299A2
- Authority
- CO
- Colombia
- Prior art keywords
- synthesis
- ester derivatives
- boronate ester
- formula
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/675—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
- B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
- B01J23/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
- B01J23/46—Ruthenium, rhodium, osmium or iridium
- B01J23/462—Ruthenium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/04—Esters of boric acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/002—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P9/00—Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Materials Engineering (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762580343P | 2017-11-01 | 2017-11-01 | |
| PCT/US2018/058143 WO2019089542A1 (en) | 2017-11-01 | 2018-10-30 | Synthesis of boronate ester derivatives and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO2020006299A2 true CO2020006299A2 (es) | 2020-06-09 |
Family
ID=66245250
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CONC2020/0006299A CO2020006299A2 (es) | 2017-11-01 | 2020-05-26 | Síntesis de derivados de éster boronato y usos de estos |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US11999757B2 (https=) |
| EP (1) | EP3704130A4 (https=) |
| JP (1) | JP7480050B2 (https=) |
| KR (1) | KR20200076730A (https=) |
| CN (2) | CN111556872B (https=) |
| AU (1) | AU2018360502B2 (https=) |
| CA (1) | CA3080763A1 (https=) |
| CL (1) | CL2020001143A1 (https=) |
| CO (1) | CO2020006299A2 (https=) |
| JO (2) | JOP20200101B1 (https=) |
| MX (2) | MX2020004425A (https=) |
| PH (1) | PH12020550544A1 (https=) |
| SG (1) | SG11202003762VA (https=) |
| WO (1) | WO2019089542A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11202003762VA (en) | 2017-11-01 | 2020-05-28 | Melinta Therapeutics Inc | Synthesis of boronate ester derivatives and uses thereof |
| CN116789689B (zh) * | 2023-06-21 | 2026-03-20 | 清华大学 | 硼代萘系化合物及其制备方法和应用 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4783443A (en) | 1986-03-03 | 1988-11-08 | The University Of Chicago | Amino acyl cephalosporin derivatives |
| JP2852545B2 (ja) | 1989-11-14 | 1999-02-03 | チッソ株式会社 | 複数の不斉点を持つ光学活性化合物および製造法 |
| CA2165996C (en) | 1995-12-22 | 2002-01-29 | Murray Douglas Bailey | Stereoselective preparation of 2-substituted succinic derivatives |
| FR2745288B1 (fr) | 1996-02-27 | 1998-04-17 | Adir | Nouveaux derives de l'acide boronique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| DE19917979A1 (de) | 1999-04-21 | 2000-10-26 | Clariant Gmbh | Verfahren zur Herstellung von substituierten Phenyl-boronsäuren |
| DE60009836T2 (de) | 1999-06-04 | 2005-04-21 | Kaneka Corp | Verfahren zur herstellung von 5-hydroxy-3-oxo-pentansäure-derivaten |
| DE10032017A1 (de) | 2000-07-01 | 2002-01-10 | Clariant Gmbh | Verfahren zur Herstellung hochreiner Formylphenylboronsäuren |
| DE10112401A1 (de) * | 2001-03-13 | 2002-09-19 | Degussa | Alkohol-Dehydrogenase und deren Verwendung |
| DE10119274A1 (de) * | 2001-04-20 | 2002-10-31 | Juelich Enzyme Products Gmbh | Enzymatisches Verfahren zur enantioselektiven Reduktion von Ketoverbindungen |
| JP4824874B2 (ja) * | 2001-07-19 | 2011-11-30 | 高砂香料工業株式会社 | 光学活性γ−ブチロラクトンの製造方法 |
| ES2544579T3 (es) * | 2002-07-30 | 2015-09-01 | Takasago International Corporation | Procedimiento de producción de un beta-aminoácido ópticamente activo |
| TWI372725B (en) | 2004-01-30 | 2012-09-21 | Semequip Inc | Methods of synthesis of isotopically enriched borohydride and methods of synthesis of isotopically enriched boranes |
| DE102004022397A1 (de) * | 2004-05-06 | 2005-12-01 | Consortium für elektrochemische Industrie GmbH | Chirale C2-symmetrische Biphenyle, deren Herstellung sowie Metallkomplexe enthaltend diese Liganden und deren Verwendung als Katalysatoren in chirogenen Synthesen |
| WO2007034909A1 (ja) | 2005-09-22 | 2007-03-29 | Kaneka Corporation | （３ｒ，５ｒ）－７－アミノ－３，５－ジヒドロキシヘプタン酸誘導体の製造法 |
| GB2474687A (en) | 2009-10-23 | 2011-04-27 | Phoenix Chemicals Ltd | A continuous process for the production of (R)-6-cyano-5-hydroxy-3-oxo-hexanoic acid tert-butyl ester (and derivatives) |
| RS60310B1 (sr) | 2010-08-10 | 2020-07-31 | Rempex Pharmaceuticals Inc | Ciklični derivati estra boronske kiseline, postupak za pripremu injihove terapeutske upotrebe |
| WO2013056163A1 (en) * | 2011-10-14 | 2013-04-18 | The Regents Of The University Of California | Beta-lactamase inhibitors |
| EP2814483A2 (en) | 2012-02-15 | 2014-12-24 | Rempex Pharmaceuticals, Inc. | Methods of treating bacterial infections |
| CN104395326B (zh) | 2012-08-20 | 2017-04-05 | 玛耐科股份有限公司 | 二取代硼酸衍生物的制造方法和新型二取代硼酸衍生物 |
| CN102965403A (zh) | 2012-11-19 | 2013-03-13 | 苏州汉酶生物技术有限公司 | (3r,5s)-6-氯-3,5-二羟基己酸叔丁酯的生物制备方法 |
| CN105026407B (zh) * | 2012-12-07 | 2017-09-08 | 维纳拓尔斯制药公司 | β‑内酰胺酶抑制剂 |
| CN105705483B (zh) | 2013-11-05 | 2018-09-04 | 伯拉考成像股份公司 | 碘帕醇的制备方法 |
| SI3140310T1 (sl) * | 2014-05-05 | 2020-01-31 | Rempex Pharmaceuticals, Inc. | Sinteza boronatnih soli in njihova uporaba |
| SG11202003762VA (en) | 2017-11-01 | 2020-05-28 | Melinta Therapeutics Inc | Synthesis of boronate ester derivatives and uses thereof |
-
2018
- 2018-10-30 SG SG11202003762VA patent/SG11202003762VA/en unknown
- 2018-10-30 JP JP2020543266A patent/JP7480050B2/ja active Active
- 2018-10-30 CN CN201880079247.3A patent/CN111556872B/zh active Active
- 2018-10-30 EP EP18874877.6A patent/EP3704130A4/en active Pending
- 2018-10-30 CA CA3080763A patent/CA3080763A1/en active Pending
- 2018-10-30 US US16/760,369 patent/US11999757B2/en active Active
- 2018-10-30 MX MX2020004425A patent/MX2020004425A/es unknown
- 2018-10-30 WO PCT/US2018/058143 patent/WO2019089542A1/en not_active Ceased
- 2018-10-30 AU AU2018360502A patent/AU2018360502B2/en active Active
- 2018-10-30 KR KR1020207015638A patent/KR20200076730A/ko not_active Ceased
- 2018-10-30 CN CN202410485244.7A patent/CN118388347A/zh active Pending
- 2018-10-31 US US16/176,302 patent/US20190127396A1/en not_active Abandoned
-
2020
- 2020-04-30 CL CL2020001143A patent/CL2020001143A1/es unknown
- 2020-05-01 PH PH12020550544A patent/PH12020550544A1/en unknown
- 2020-05-06 JO JOJO/P/2020/0101A patent/JOP20200101B1/ar active
- 2020-05-26 CO CONC2020/0006299A patent/CO2020006299A2/es unknown
- 2020-07-13 MX MX2023000529A patent/MX2023000529A/es unknown
-
2024
- 2024-04-04 US US18/627,105 patent/US20240279248A1/en active Pending
- 2024-10-20 JO JOJO/P/2024/0234A patent/JOP20240234A1/ar unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20240279248A1 (en) | 2024-08-22 |
| CN111556872A (zh) | 2020-08-18 |
| AU2018360502A1 (en) | 2020-06-04 |
| US11999757B2 (en) | 2024-06-04 |
| MX2020004425A (es) | 2020-08-06 |
| JP2021501205A (ja) | 2021-01-14 |
| CA3080763A1 (en) | 2019-05-09 |
| BR112020008498A2 (pt) | 2020-10-20 |
| US20200308197A1 (en) | 2020-10-01 |
| PH12020550544A1 (en) | 2021-03-22 |
| CN111556872B (zh) | 2024-05-10 |
| AU2018360502B2 (en) | 2024-05-02 |
| SG11202003762VA (en) | 2020-05-28 |
| EP3704130A4 (en) | 2021-07-07 |
| EP3704130A1 (en) | 2020-09-09 |
| JOP20200101A1 (ar) | 2022-10-30 |
| JOP20240234A1 (ar) | 2024-10-20 |
| MX2023000529A (es) | 2023-02-13 |
| US20190127396A1 (en) | 2019-05-02 |
| CN118388347A (zh) | 2024-07-26 |
| KR20200076730A (ko) | 2020-06-29 |
| CL2020001143A1 (es) | 2020-10-30 |
| JOP20200101B1 (ar) | 2024-12-22 |
| WO2019089542A1 (en) | 2019-05-09 |
| JP7480050B2 (ja) | 2024-05-09 |
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