MX2023000529A - Sintesis de derivados de ester boronato y usos de estos. - Google Patents
Sintesis de derivados de ester boronato y usos de estos.Info
- Publication number
- MX2023000529A MX2023000529A MX2023000529A MX2023000529A MX2023000529A MX 2023000529 A MX2023000529 A MX 2023000529A MX 2023000529 A MX2023000529 A MX 2023000529A MX 2023000529 A MX2023000529 A MX 2023000529A MX 2023000529 A MX2023000529 A MX 2023000529A
- Authority
- MX
- Mexico
- Prior art keywords
- synthesis
- ester derivatives
- boronate ester
- formula
- disclosed
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- -1 boronate ester Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102000007698 Alcohol dehydrogenase Human genes 0.000 abstract 1
- 108010021809 Alcohol dehydrogenase Proteins 0.000 abstract 1
- KJTLSVCANCCWHF-UHFFFAOYSA-N Ruthenium Chemical compound [Ru] KJTLSVCANCCWHF-UHFFFAOYSA-N 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- ZADPBFCGQRWHPN-UHFFFAOYSA-N boronic acid Chemical class OBO ZADPBFCGQRWHPN-UHFFFAOYSA-N 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 125000000468 ketone group Chemical group 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 229910052707 ruthenium Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/675—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
- B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
- B01J23/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
- B01J23/46—Ruthenium, rhodium, osmium or iridium
- B01J23/462—Ruthenium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/04—Esters of boric acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/002—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P9/00—Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Materials Engineering (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Catalysts (AREA)
Abstract
En la presente descripción se describen los métodos para la preparación de derivados de boronato en la síntesis de compuestos antimicrobianos y sus usos. En la presente descripción se describen los métodos para preparar un compuesto de la Fórmula (B) mediante la reducción del grupo cetona del compuesto cetoéster de la Fórmula (A), y la reducción puede realizarse mediante el uso de un sistema catalítico que se basa en Rutenio o mediante el uso de un sistema de biorreducción de la alcohol deshidrogenasa.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762580343P | 2017-11-01 | 2017-11-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2023000529A true MX2023000529A (es) | 2023-02-13 |
Family
ID=66245250
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020004425A MX2020004425A (es) | 2017-11-01 | 2018-10-30 | Síntesis de derivados de éster boronato y usos de estos. |
MX2023000529A MX2023000529A (es) | 2017-11-01 | 2020-07-13 | Sintesis de derivados de ester boronato y usos de estos. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020004425A MX2020004425A (es) | 2017-11-01 | 2018-10-30 | Síntesis de derivados de éster boronato y usos de estos. |
Country Status (15)
Country | Link |
---|---|
US (2) | US20200308197A1 (es) |
EP (1) | EP3704130A4 (es) |
JP (1) | JP7480050B2 (es) |
KR (1) | KR20200076730A (es) |
CN (1) | CN111556872B (es) |
AU (1) | AU2018360502B2 (es) |
BR (1) | BR112020008498A2 (es) |
CA (1) | CA3080763A1 (es) |
CL (1) | CL2020001143A1 (es) |
CO (1) | CO2020006299A2 (es) |
JO (1) | JOP20200101A1 (es) |
MX (2) | MX2020004425A (es) |
PH (1) | PH12020550544A1 (es) |
SG (1) | SG11202003762VA (es) |
WO (1) | WO2019089542A1 (es) |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4783443A (en) | 1986-03-03 | 1988-11-08 | The University Of Chicago | Amino acyl cephalosporin derivatives |
DE10119274A1 (de) * | 2001-04-20 | 2002-10-31 | Juelich Enzyme Products Gmbh | Enzymatisches Verfahren zur enantioselektiven Reduktion von Ketoverbindungen |
EP1386901B1 (en) * | 2002-07-30 | 2015-07-01 | Takasago International Corporation | Method for producing an optically active beta-amino acid |
DE102004022397A1 (de) * | 2004-05-06 | 2005-12-01 | Consortium für elektrochemische Industrie GmbH | Chirale C2-symmetrische Biphenyle, deren Herstellung sowie Metallkomplexe enthaltend diese Liganden und deren Verwendung als Katalysatoren in chirogenen Synthesen |
WO2007034909A1 (ja) * | 2005-09-22 | 2007-03-29 | Kaneka Corporation | (3r,5r)-7-アミノ-3,5-ジヒドロキシヘプタン酸誘導体の製造法 |
BR112013003045B1 (pt) * | 2010-08-10 | 2021-08-31 | Rempex Pharmaceuticals, Inc. | Composto e respectivo uso, composição farmacêutica, recipiente estéril e método para preparar composição farmacêutica para administração |
WO2013056163A1 (en) * | 2011-10-14 | 2013-04-18 | The Regents Of The University Of California | Beta-lactamase inhibitors |
WO2013122888A2 (en) * | 2012-02-15 | 2013-08-22 | Rempex Pharmaceuticals, Inc. | Methods of treating bacterial infections |
US9422314B2 (en) * | 2012-12-07 | 2016-08-23 | VenatoRx Pharmaceuticals, Inc. | Beta-lactamase inhibitors |
EP4356736A2 (en) * | 2014-05-05 | 2024-04-24 | Melinta Therapeutics, Inc. | Synthesis of boronate salts |
-
2018
- 2018-10-30 KR KR1020207015638A patent/KR20200076730A/ko not_active Application Discontinuation
- 2018-10-30 CA CA3080763A patent/CA3080763A1/en active Pending
- 2018-10-30 MX MX2020004425A patent/MX2020004425A/es unknown
- 2018-10-30 EP EP18874877.6A patent/EP3704130A4/en active Pending
- 2018-10-30 US US16/760,369 patent/US20200308197A1/en active Pending
- 2018-10-30 JO JOP/2020/0101A patent/JOP20200101A1/ar unknown
- 2018-10-30 BR BR112020008498-0A patent/BR112020008498A2/pt active Search and Examination
- 2018-10-30 AU AU2018360502A patent/AU2018360502B2/en active Active
- 2018-10-30 CN CN201880079247.3A patent/CN111556872B/zh active Active
- 2018-10-30 SG SG11202003762VA patent/SG11202003762VA/en unknown
- 2018-10-30 JP JP2020543266A patent/JP7480050B2/ja active Active
- 2018-10-30 WO PCT/US2018/058143 patent/WO2019089542A1/en active Application Filing
- 2018-10-31 US US16/176,302 patent/US20190127396A1/en not_active Abandoned
-
2020
- 2020-04-30 CL CL2020001143A patent/CL2020001143A1/es unknown
- 2020-05-01 PH PH12020550544A patent/PH12020550544A1/en unknown
- 2020-05-26 CO CONC2020/0006299A patent/CO2020006299A2/es unknown
- 2020-07-13 MX MX2023000529A patent/MX2023000529A/es unknown
Also Published As
Publication number | Publication date |
---|---|
AU2018360502A1 (en) | 2020-06-04 |
CL2020001143A1 (es) | 2020-10-30 |
CA3080763A1 (en) | 2019-05-09 |
CN111556872A (zh) | 2020-08-18 |
MX2020004425A (es) | 2020-08-06 |
KR20200076730A (ko) | 2020-06-29 |
WO2019089542A1 (en) | 2019-05-09 |
EP3704130A4 (en) | 2021-07-07 |
PH12020550544A1 (en) | 2021-03-22 |
EP3704130A1 (en) | 2020-09-09 |
BR112020008498A2 (pt) | 2020-10-20 |
CO2020006299A2 (es) | 2020-06-09 |
AU2018360502B2 (en) | 2024-05-02 |
JP2021501205A (ja) | 2021-01-14 |
JP7480050B2 (ja) | 2024-05-09 |
CN111556872B (zh) | 2024-05-10 |
SG11202003762VA (en) | 2020-05-28 |
JOP20200101A1 (ar) | 2022-10-30 |
US20200308197A1 (en) | 2020-10-01 |
US20190127396A1 (en) | 2019-05-02 |
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