JO3680B1 - تركيبات صيدلانية موضعية - Google Patents
تركيبات صيدلانية موضعيةInfo
- Publication number
- JO3680B1 JO3680B1 JOP/2016/0097A JOP20160097A JO3680B1 JO 3680 B1 JO3680 B1 JO 3680B1 JO P20160097 A JOP20160097 A JO P20160097A JO 3680 B1 JO3680 B1 JO 3680B1
- Authority
- JO
- Jordan
- Prior art keywords
- topical pharmaceutical
- pharmaceutical compositions
- patient
- relates
- oil phase
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
يتعلق الاختراع الحالي بتركيبات مستحلبة صيدلانية موضعية تتضمن كمية فعالة علاجياً من 3، 5- ثاني هيدروكسي-4- أيزوبروبيل-ترانس- ستيلبين أو ملح مقبول صيدلانيا منه، طور زيتي، طور مائي، منشط للسطح، ومضاد للأكسدة، وفيها التركيب المستحلب عبارة عن مستحلب متجانس أو نشط والذي يذاب في طور الزيت. ويتعلق الاختراع أيضاً بطرق لعلاج حالات جلدية أو اضطراب الجلد في مريض بإعطاء التركيبات الحالية إلى جلد المريض
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562165097P | 2015-05-21 | 2015-05-21 | |
US201662324450P | 2016-04-19 | 2016-04-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
JO3680B1 true JO3680B1 (ar) | 2020-08-27 |
Family
ID=56081527
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JOP/2016/0097A JO3680B1 (ar) | 2015-05-21 | 2016-05-19 | تركيبات صيدلانية موضعية |
Country Status (34)
Country | Link |
---|---|
US (5) | US10195160B2 (ar) |
EP (2) | EP4094752A1 (ar) |
JP (3) | JP6863904B2 (ar) |
KR (1) | KR20180008490A (ar) |
CN (2) | CN107666902B (ar) |
AU (2) | AU2016263161B2 (ar) |
BR (1) | BR112017024934A8 (ar) |
CA (1) | CA2986251A1 (ar) |
CL (1) | CL2017002939A1 (ar) |
CO (1) | CO2017011795A2 (ar) |
CR (1) | CR20170528A (ar) |
DK (1) | DK3297605T3 (ar) |
DO (1) | DOP2017000270A (ar) |
EA (1) | EA038624B1 (ar) |
ES (1) | ES2914112T3 (ar) |
HK (1) | HK1245074A1 (ar) |
HR (1) | HRP20220670T1 (ar) |
HU (1) | HUE059066T2 (ar) |
IL (2) | IL255203B (ar) |
JO (1) | JO3680B1 (ar) |
LT (1) | LT3297605T (ar) |
MX (2) | MX2017014804A (ar) |
PE (1) | PE20180038A1 (ar) |
PH (1) | PH12017502092A1 (ar) |
PL (1) | PL3297605T3 (ar) |
PT (1) | PT3297605T (ar) |
RS (1) | RS63402B1 (ar) |
SG (1) | SG11201708666RA (ar) |
SI (1) | SI3297605T1 (ar) |
TW (1) | TWI705831B (ar) |
UA (1) | UA125500C2 (ar) |
UY (1) | UY36682A (ar) |
WO (1) | WO2016185428A1 (ar) |
ZA (1) | ZA202007965B (ar) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
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US11617724B2 (en) | 2015-05-21 | 2023-04-04 | Dermavant Sciences GmbH | Topical pharmaceutical compositions |
RS63402B1 (sr) * | 2015-05-21 | 2022-08-31 | Dermavant Sciences GmbH | Topikalne farmaceutske kompozicije |
BR112020009158A2 (pt) * | 2017-11-10 | 2020-10-27 | Dermavant Sciences GmbH | processo para o preparo de um composto, composto e composição farmacêutica |
CN109085257B (zh) * | 2018-07-05 | 2021-04-06 | 中央民族大学 | 一种同时定量检测小鼠血浆中黄芪甲苷-iv、环黄芪醇的方法 |
US11497718B2 (en) | 2018-11-13 | 2022-11-15 | Dermavant Sciences GmbH | Use of tapinarof for the treatment of atopic dermatitis |
KR20230110821A (ko) * | 2019-04-17 | 2023-07-25 | 아조라 테라퓨틱스 인코포레이티드 | 염증성 피부 질환을 치료하기 위한 국소 조성물 및방법 |
US20200383887A1 (en) * | 2019-06-04 | 2020-12-10 | L'oreal | Oxygenate skin treatment system |
BR112021026532A2 (pt) | 2019-06-26 | 2022-05-24 | Locus Oil Ip Company Llc | Composições multifuncionais compreendendo ácidos concentrados para recuperação melhorada de petróleo e gás |
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US20220331268A1 (en) * | 2019-09-26 | 2022-10-20 | Sol-Gel Technologies Ltd. | Treatment of skin disorders with topical combination compositions comprising tapinarof and an additional ahr activator |
MX2022005448A (es) * | 2019-11-06 | 2022-07-21 | Sol Gel Tech Ltd | Método de tratamiento de queratodermia palmoplantar. |
EP4061332A4 (en) * | 2019-11-24 | 2023-11-29 | Sol-Gel Technologies Ltd. | TREATMENT OF SKIN DISEASES USING TOPICAL COMPOSITIONS CONTAINING TAPINAROF AND A PDE4 INHIBITOR |
US11154486B2 (en) | 2020-02-14 | 2021-10-26 | William M. Yarbrough Foundation | Detergent compositions for washing urushiol and methods of treating urushiol induced contact dermatitis |
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EP4171529A4 (en) * | 2020-06-24 | 2024-05-01 | Dermavant Sciences GmbH | TOPICAL PHARMACEUTICAL COMPOSITIONS |
AU2022223701A1 (en) * | 2021-02-17 | 2023-09-07 | Dermavant Sciences GmbH | Remittive effects of tapinarof in the treatment of plaque psoriasis, atopic dermatitis, or radiation dermatitis |
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EP2645993B1 (en) | 2010-12-03 | 2016-11-02 | Allergan, Inc. | Pharmaceutical cream compositions comprising oxymetazoline |
EP2723889B1 (en) | 2011-06-27 | 2019-11-06 | Galderma Research & Development | New th17 differentiation markers for acne and uses thereof |
WO2013130535A1 (en) | 2012-02-27 | 2013-09-06 | Newgen Biopharma Corporation | Topical delivery of hormonal and non hormonal nano formulations, methods of making and using the same |
CN102657610A (zh) | 2012-05-11 | 2012-09-12 | 河北科技大学 | 3,5-二羟基-4-异丙基二苯乙烯微乳剂及其制备方法 |
CN102657602B (zh) | 2012-05-22 | 2013-08-07 | 河北科技大学 | 3,5-二羟基-4-异丙基二苯乙烯壳聚糖凝胶剂及其制备方法 |
US9433680B2 (en) * | 2013-01-31 | 2016-09-06 | Merz Pharmaceuticals, Llc | Topical compositions and methods for making and using same |
CN103315958B (zh) | 2013-07-19 | 2014-10-29 | 河北科技大学 | 苯烯莫德纳米乳及其制备方法 |
US9925153B2 (en) | 2013-12-06 | 2018-03-27 | Stc.Unm | Therapeutic agents for skin diseases and conditions |
CN103992212B (zh) * | 2014-05-29 | 2015-07-01 | 河北科技大学 | 顺式苯烯莫德的合成方法及顺式苯烯莫德的应用 |
CA2970739C (en) | 2014-12-12 | 2023-10-03 | Glaxosmithkline Intellectual Property Development Limited | Use of 3,5-dihydroxy-4-isopropyl-trans-stilbene, for treating skin conditions |
RS63402B1 (sr) | 2015-05-21 | 2022-08-31 | Dermavant Sciences GmbH | Topikalne farmaceutske kompozicije |
US11617724B2 (en) | 2015-05-21 | 2023-04-04 | Dermavant Sciences GmbH | Topical pharmaceutical compositions |
BR112020009158A2 (pt) | 2017-11-10 | 2020-10-27 | Dermavant Sciences GmbH | processo para o preparo de um composto, composto e composição farmacêutica |
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2016
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