ITRM20020194A1 - Composizione utile per aumentare la concentrazione e la motilita' degli spermatozoi e migliorarne la morfologia nell'uomo. - Google Patents
Composizione utile per aumentare la concentrazione e la motilita' degli spermatozoi e migliorarne la morfologia nell'uomo.Info
- Publication number
- ITRM20020194A1 ITRM20020194A1 IT2002RM000194A ITRM20020194A ITRM20020194A1 IT RM20020194 A1 ITRM20020194 A1 IT RM20020194A1 IT 2002RM000194 A IT2002RM000194 A IT 2002RM000194A IT RM20020194 A ITRM20020194 A IT RM20020194A IT RM20020194 A1 ITRM20020194 A1 IT RM20020194A1
- Authority
- IT
- Italy
- Prior art keywords
- spermatozoi
- motility
- morphology
- man
- concentration
- Prior art date
Links
- 230000004899 motility Effects 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 2
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 abstract 1
- 206010067162 Asthenospermia Diseases 0.000 abstract 1
- RDHQFKQIGNGIED-MRVPVSSYSA-N O-acetyl-L-carnitine Chemical compound CC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C RDHQFKQIGNGIED-MRVPVSSYSA-N 0.000 abstract 1
- UFAHZIUFPNSHSL-MRVPVSSYSA-N O-propanoyl-L-carnitine Chemical compound CCC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C UFAHZIUFPNSHSL-MRVPVSSYSA-N 0.000 abstract 1
- 206010050208 Teratospermia Diseases 0.000 abstract 1
- 208000002312 Teratozoospermia Diseases 0.000 abstract 1
- 206010003883 azoospermia Diseases 0.000 abstract 1
- 208000008634 oligospermia Diseases 0.000 abstract 1
- 230000036616 oligospermia Effects 0.000 abstract 1
- 231100000528 oligospermia Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Organic Chemistry (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Priority Applications (21)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2002RM000194A ITRM20020194A1 (it) | 2002-04-09 | 2002-04-09 | Composizione utile per aumentare la concentrazione e la motilita' degli spermatozoi e migliorarne la morfologia nell'uomo. |
| PT03720869T PT1492521E (pt) | 2002-04-09 | 2003-04-08 | Utilização combinada de l-carnitina, acetil l-carnitina e propionil l-carnitina para o tratamento da oligoastenoteratozoospermia |
| ES03720869T ES2350338T3 (es) | 2002-04-09 | 2003-04-08 | Uso combinado del l-carnitina, acetil l-carnitina y propionil l-carnitina para el tratamiento de oligoastenoteratospermia. |
| DK03720869.1T DK1492521T3 (da) | 2002-04-09 | 2003-04-08 | Kombineret brug af L-carnitin, acetyl-L-carnitin og propionyl-L-carnitin i behandling af oligoasthenoteratospermi |
| AT03720869T ATE476974T1 (de) | 2002-04-09 | 2003-04-08 | Verwendung einer kombination von l-carnitin, acetyl l-carnitin und propionyl l-carnitin zur behandlung von oligoasthenoteratospermia |
| DE60333742T DE60333742D1 (de) | 2002-04-09 | 2003-04-08 | Verwendung einer kombination von l-carnitin, acetyl l-carnitin und propionyl l-carnitin zur behandlung von oligoasthenoteratospermia |
| PL372924A PL214859B1 (pl) | 2002-04-09 | 2003-04-08 | Laczne zastosowanie L-karnityny, acetylo L-karnityny i propionylo L-karnityny do leczenia oligoastenoteratospermii |
| BR0309055-8A BR0309055A (pt) | 2002-04-09 | 2003-04-08 | Uso combinado de l-carnitina, acetil l-carnitina e propionil l-carnitina para o tratamento da oligoastenoteratospermia |
| EP03720869A EP1492521B1 (en) | 2002-04-09 | 2003-04-08 | Combined use of l-carnitine, acetyl l-carnitine and propionyl l-carnitine for the treatment of oligoasthenoteratospermia |
| CA2478674A CA2478674C (en) | 2002-04-09 | 2003-04-08 | Combined use of l-carnitine, acetyl l-carnitine and propionyl l-carnitine for the treatment of oligoasthenoteratospermia |
| PCT/IT2003/000214 WO2003084526A1 (en) | 2002-04-09 | 2003-04-08 | Combined use of l-carnitine, acetyl l-carnitine and propionyl l-carnitine for the treatment of oligoasthenoteratospermia |
| JP2003581766A JP4663987B2 (ja) | 2002-04-09 | 2003-04-08 | 精子減少・無力・奇形症の治療のためのｌ−カルニチン、アセチルｌ−カルニチンおよびプロピオニルｌ−カルニチンの併用 |
| AU2003224443A AU2003224443B2 (en) | 2002-04-09 | 2003-04-08 | Combined use of L-carnitine, acetyl L-carnitine and propionyl L-carnitine for the treatment of oligoasthenoteratospermia |
| US10/510,450 US20050107470A1 (en) | 2002-04-09 | 2003-04-08 | Combined use of l-carnitine, acetyl l-carnitine and propionyl l-carnitine for the treatment of oligoasthenoteratospermia |
| SI200331892T SI1492521T1 (sl) | 2002-04-09 | 2003-04-08 | Kombinirana uporaba l-karnitina, acetil l-karnitina in propil l-karnitina za zdravljenje oligoastenoteratospermije |
| MXPA04009763A MXPA04009763A (es) | 2002-04-09 | 2003-04-08 | Uso combinado del l-carnitina, acetil l-carnitina y propionil l-carnitina para el tratamiento de oligoastenoteratospermia. |
| CNB038050935A CN1330301C (zh) | 2002-04-09 | 2003-04-08 | L－肉碱、乙酰l－肉碱和丙酰l－肉碱在制备治疗精子减少精子活力不足畸形精子的联合药物中的应用 |
| HK05110357.1A HK1078460B (en) | 2002-04-09 | 2003-04-08 | Use of l-carnitine, acetyl l-carnitine and propionyl l-carnitine in the manufacture of a combined medicament for the treatment of oligoasthenoteratospermia |
| KR10-2004-7013385A KR20040098005A (ko) | 2002-04-09 | 2003-04-08 | 무력성 기형 정자 부족증의 치료를 위한 ｌ－카르니틴,아세틸 ｌ－카르니틴 및 프로피오닐 ｌ－카르니틴의 복합용도 |
| US12/230,992 US8415392B2 (en) | 2002-04-09 | 2008-09-09 | Combined use of L-carnitine, acetyle L-carnitine and propionyl L-carnitine for the treatment of oligoasthenoteratospermia |
| CY20101100989T CY1111273T1 (el) | 2002-04-09 | 2010-11-03 | Συνδυασμενη χρηση της l-καρνιτινης, ακετυλο l-καρνιτινης και προπιονυλο l-καρνιτινης για τη θεραπεια της ολιγοασθενοτερατοσπερμιας |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2002RM000194A ITRM20020194A1 (it) | 2002-04-09 | 2002-04-09 | Composizione utile per aumentare la concentrazione e la motilita' degli spermatozoi e migliorarne la morfologia nell'uomo. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ITRM20020194A0 ITRM20020194A0 (it) | 2002-04-09 |
| ITRM20020194A1 true ITRM20020194A1 (it) | 2003-10-09 |
Family
ID=11456235
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT2002RM000194A ITRM20020194A1 (it) | 2002-04-09 | 2002-04-09 | Composizione utile per aumentare la concentrazione e la motilita' degli spermatozoi e migliorarne la morfologia nell'uomo. |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US20050107470A1 (enExample) |
| EP (1) | EP1492521B1 (enExample) |
| JP (1) | JP4663987B2 (enExample) |
| KR (1) | KR20040098005A (enExample) |
| CN (1) | CN1330301C (enExample) |
| AT (1) | ATE476974T1 (enExample) |
| AU (1) | AU2003224443B2 (enExample) |
| BR (1) | BR0309055A (enExample) |
| CA (1) | CA2478674C (enExample) |
| CY (1) | CY1111273T1 (enExample) |
| DE (1) | DE60333742D1 (enExample) |
| DK (1) | DK1492521T3 (enExample) |
| ES (1) | ES2350338T3 (enExample) |
| IT (1) | ITRM20020194A1 (enExample) |
| MX (1) | MXPA04009763A (enExample) |
| PL (1) | PL214859B1 (enExample) |
| PT (1) | PT1492521E (enExample) |
| SI (1) | SI1492521T1 (enExample) |
| WO (1) | WO2003084526A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7776913B2 (en) | 2002-12-13 | 2010-08-17 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Carnitines for treating or preventing disorders caused by andropause |
| EP2429299B1 (en) | 2009-05-01 | 2016-06-01 | Celloxess Llc | Treating male infertility secondary to sperm oxidative stress |
| US20110015154A1 (en) * | 2009-07-20 | 2011-01-20 | Kellermann Gottfried H | Supporting acetylcholine function |
| US20110098265A1 (en) * | 2009-10-28 | 2011-04-28 | Neuroscience, Inc. | Methods for reducing cravings and impulses associated with addictive and compulsive behaviors |
| CN108041588A (zh) * | 2017-12-08 | 2018-05-18 | 冯纪敏 | 一种含有海藻糖的组合物及其应用 |
| CN109999042B (zh) * | 2019-05-16 | 2021-05-18 | 北京华睿鼎信科技有限公司 | 包含脱氢表雄酮或其硫酸酯、左卡尼汀、乙酰左卡尼汀或它们的可药用盐的组合物及其应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1249462B (it) * | 1991-10-21 | 1995-02-23 | Sigma Tau Ind Farmaceuti | Impiego di l-carnitina e acil l-carnitine nel trattamento delle oligoastenospermie idiopatiche. |
| IT1291127B1 (it) * | 1997-04-01 | 1998-12-29 | Sigma Tau Ind Farmaceuti | Integratore alimentare per soggetti dediti ad intensa e prolungata attivita' fisica |
| IT1295408B1 (it) * | 1997-10-03 | 1999-05-12 | Sigma Tau Ind Farmaceuti | Associazione di l-carnitina e alcanoil l-carnitine per il trattamento dell'alcoolismo |
| GB9721746D0 (en) | 1997-10-15 | 1997-12-10 | Panos Therapeutics Limited | Compositions |
| US6090848A (en) * | 1997-12-01 | 2000-07-18 | Sigma-Tau Healthscience S.P.A. | Compositions and methods for increasing the concentration and/or motility of spermatozoa in humans |
| ITRM20010029A1 (it) * | 2001-01-23 | 2002-07-23 | Aldo Fassi | Sali metallici di carnitine utili come integratori dietetici/nutrizionali o come farmaci, composizioni che li contengono e procedimenti per |
| ITRM20020055A1 (it) | 2002-02-04 | 2003-08-04 | Aldo Fassi | Sali metallici di carnitine, integratori dietetici/nutritivi che li contengono e kit dietetici per contrastare disturbi sessuali in soggetti |
-
2002
- 2002-04-09 IT IT2002RM000194A patent/ITRM20020194A1/it unknown
-
2003
- 2003-04-08 ES ES03720869T patent/ES2350338T3/es not_active Expired - Lifetime
- 2003-04-08 AU AU2003224443A patent/AU2003224443B2/en not_active Expired
- 2003-04-08 MX MXPA04009763A patent/MXPA04009763A/es active IP Right Grant
- 2003-04-08 WO PCT/IT2003/000214 patent/WO2003084526A1/en not_active Ceased
- 2003-04-08 AT AT03720869T patent/ATE476974T1/de active
- 2003-04-08 CN CNB038050935A patent/CN1330301C/zh not_active Expired - Lifetime
- 2003-04-08 KR KR10-2004-7013385A patent/KR20040098005A/ko not_active Ceased
- 2003-04-08 PT PT03720869T patent/PT1492521E/pt unknown
- 2003-04-08 US US10/510,450 patent/US20050107470A1/en not_active Abandoned
- 2003-04-08 JP JP2003581766A patent/JP4663987B2/ja not_active Expired - Lifetime
- 2003-04-08 EP EP03720869A patent/EP1492521B1/en not_active Expired - Lifetime
- 2003-04-08 SI SI200331892T patent/SI1492521T1/sl unknown
- 2003-04-08 PL PL372924A patent/PL214859B1/pl unknown
- 2003-04-08 CA CA2478674A patent/CA2478674C/en not_active Expired - Lifetime
- 2003-04-08 DE DE60333742T patent/DE60333742D1/de not_active Expired - Lifetime
- 2003-04-08 BR BR0309055-8A patent/BR0309055A/pt not_active Application Discontinuation
- 2003-04-08 DK DK03720869.1T patent/DK1492521T3/da active
-
2008
- 2008-09-09 US US12/230,992 patent/US8415392B2/en not_active Expired - Fee Related
-
2010
- 2010-11-03 CY CY20101100989T patent/CY1111273T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2350338T3 (es) | 2011-01-21 |
| PT1492521E (pt) | 2010-11-11 |
| ITRM20020194A0 (it) | 2002-04-09 |
| AU2003224443B2 (en) | 2008-09-11 |
| PL214859B1 (pl) | 2013-09-30 |
| KR20040098005A (ko) | 2004-11-18 |
| CN1638754A (zh) | 2005-07-13 |
| JP2006505499A (ja) | 2006-02-16 |
| CN1330301C (zh) | 2007-08-08 |
| BR0309055A (pt) | 2005-02-22 |
| CA2478674A1 (en) | 2003-10-16 |
| SI1492521T1 (sl) | 2010-12-31 |
| US20050107470A1 (en) | 2005-05-19 |
| HK1078460A1 (en) | 2006-03-17 |
| EP1492521A1 (en) | 2005-01-05 |
| CA2478674C (en) | 2010-10-19 |
| WO2003084526A1 (en) | 2003-10-16 |
| AU2003224443A1 (en) | 2003-10-20 |
| DK1492521T3 (da) | 2010-11-22 |
| US20090012169A1 (en) | 2009-01-08 |
| US8415392B2 (en) | 2013-04-09 |
| JP4663987B2 (ja) | 2011-04-06 |
| DE60333742D1 (de) | 2010-09-23 |
| EP1492521B1 (en) | 2010-08-11 |
| PL372924A1 (en) | 2005-08-08 |
| MXPA04009763A (es) | 2004-12-13 |
| CY1111273T1 (el) | 2015-08-05 |
| ATE476974T1 (de) | 2010-08-15 |
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