NO20026076D0 - Kombinert terapi mot tumorer innbefattende substituerte akryloyldistamycinderivater, taksaner og/eller antimetabolitter - Google Patents
Kombinert terapi mot tumorer innbefattende substituerte akryloyldistamycinderivater, taksaner og/eller antimetabolitterInfo
- Publication number
- NO20026076D0 NO20026076D0 NO20026076A NO20026076A NO20026076D0 NO 20026076 D0 NO20026076 D0 NO 20026076D0 NO 20026076 A NO20026076 A NO 20026076A NO 20026076 A NO20026076 A NO 20026076A NO 20026076 D0 NO20026076 D0 NO 20026076D0
- Authority
- NO
- Norway
- Prior art keywords
- taxanes
- antimetabolites
- distamycin derivatives
- acryloyl distamycin
- combined therapy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Epoxy Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0015446.8A GB0015446D0 (en) | 2000-06-23 | 2000-06-23 | Combined therapy against tumors comprising substituted acryloyl distamycin derivates,taxanes and/or antimetabolites |
| PCT/EP2001/007060 WO2001097618A2 (en) | 2000-06-23 | 2001-06-20 | Combined therapy against tumors comprising substituted acryloyl distamycin derivatives, taxanes and/or antimetabolites |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20026076L NO20026076L (no) | 2002-12-18 |
| NO20026076D0 true NO20026076D0 (no) | 2002-12-18 |
| NO329967B1 NO329967B1 (no) | 2011-01-31 |
Family
ID=9894287
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20026076A NO329967B1 (no) | 2000-06-23 | 2002-12-18 | Farmasoytisk preparat og produkter innbefattende akryloyldistamycinderivater og antimetabolitter, samt anvendelse derav |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7642229B2 (no) |
| EP (2) | EP1299110B1 (no) |
| JP (1) | JP2003535874A (no) |
| KR (1) | KR100861668B1 (no) |
| CN (1) | CN100479824C (no) |
| AT (2) | ATE415165T1 (no) |
| AU (2) | AU2001267553B2 (no) |
| BR (1) | BR0111814A (no) |
| CA (1) | CA2412054A1 (no) |
| CZ (1) | CZ20024107A3 (no) |
| DE (2) | DE60136706D1 (no) |
| EA (1) | EA006709B1 (no) |
| EE (1) | EE05359B1 (no) |
| ES (1) | ES2317913T3 (no) |
| GB (1) | GB0015446D0 (no) |
| HK (1) | HK1054506B (no) |
| HU (1) | HUP0301334A3 (no) |
| IL (2) | IL153178A0 (no) |
| MX (1) | MXPA02012165A (no) |
| NO (1) | NO329967B1 (no) |
| NZ (2) | NZ523001A (no) |
| PL (1) | PL200504B1 (no) |
| SK (1) | SK287398B6 (no) |
| WO (1) | WO2001097618A2 (no) |
| ZA (1) | ZA200209835B (no) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070249651A1 (en) * | 2001-06-20 | 2007-10-25 | Nerviano Medical Sciences S.R.I. | Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors |
| MD36Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de tratament diferenţiat al carcinomului ductal in situ neinvaziv al glandei mamare |
| MD24Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de tratament diferenţiat al carcinomului neinvaziv al glandei mamare |
| MD35Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de apreciere a riscului dezvoltării carcinomului neinvaziv in situ al glandei mamare |
| MD23Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de tratament diferenţiat al carcinomului lobular in situ neinvaziv al glandei mamare |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT387013B (de) | 1985-07-16 | 1988-11-25 | Erba Farmitalia | Verfahren zur herstellung von poly-4-aminopyrrol -2-carboxamidoderivaten |
| GB8612218D0 (en) | 1986-05-20 | 1986-06-25 | Erba Farmitalia | Site specific alkylating agents |
| IL84114A (en) | 1986-10-07 | 1994-01-25 | Boehringer Mannheim Italia | Anti-neoplastic pharmaceutical compositions containing HSG together with an anti-tumor drug |
| GB8906709D0 (en) | 1989-03-23 | 1989-05-10 | Creighton Andrew M | Acryloyl substituted pyrrole derivatives |
| JP2919867B2 (ja) | 1989-09-27 | 1999-07-19 | 千寿製薬株式会社 | 抗腫瘍剤 |
| WO1994001112A1 (en) * | 1992-07-07 | 1994-01-20 | Sepracor Inc. | Methods of using (-) cisapride for the treatment of gastro-esophageal reflux disease and other disorders |
| US5633274A (en) * | 1993-02-18 | 1997-05-27 | President And Fellows Of Harvard College | Cancer treatments |
| IT1272234B (it) | 1994-05-02 | 1997-06-16 | Consiglio Nazionale Ricerche | Derivati glutationici delle antracicline e procedimento per ottenerli. |
| GB9416005D0 (en) | 1994-08-08 | 1994-09-28 | Erba Carlo Spa | Peptidic compounds analogous to distamycin a and process for their preparation |
| US5597830A (en) * | 1994-12-20 | 1997-01-28 | Warner-Lambert Company | Combination chemotherapy |
| US5880097A (en) | 1996-01-04 | 1999-03-09 | Terrapin Techologies, Inc. | Tethered prodrugs |
| WO1997028123A1 (en) | 1996-02-02 | 1997-08-07 | Pharmacia & Upjohn S.P.A. | Distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents |
| GB9610079D0 (en) | 1996-05-14 | 1996-07-17 | Pharmacia Spa | Distamycin deriratives process for preparing them and their use as antitumor and antiviral agents |
| GB9615692D0 (en) * | 1996-07-25 | 1996-09-04 | Pharmacia Spa | Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents |
| GB9623522D0 (en) | 1996-11-11 | 1997-01-08 | Pharmacia & Upjohn Spa | Benzoheterocycle distamycin derivatives process for preparing them and their use as antitumour and antiviral agents |
| GB9727524D0 (en) | 1997-12-31 | 1998-02-25 | Pharmacia & Upjohn Spa | Synergistic antitumor composition containing a biologically active ureido compound |
| GB9806689D0 (en) | 1998-03-27 | 1998-05-27 | Pharmacia & Upjohn Spa | Acryloyl derivatives analogous to distamycin,process for preparing them,and their use as antitumour and antiviral agents |
| GB9806692D0 (en) | 1998-03-27 | 1998-05-27 | Pharmacia & Upjohn Spa | Benzoheterocyclic distamycin derivatives, process for preparing them and their use as antitumour agents |
| GB9816653D0 (en) | 1998-07-30 | 1998-09-30 | Pharmacia & Upjohn Spa | Oxidised sulfurated distamycin derivatives process for preparing them and their use as antitumor agents |
| GB9816652D0 (en) | 1998-07-30 | 1998-09-30 | Pharmacia & Upjohn Spa | Sulfurated distamycin derivatives process for preparing them and their use as antitumor agents |
| GB9928703D0 (en) | 1999-12-03 | 2000-02-02 | Pharmacia & Upjohn Spa | Acryloyl peptidic derivatives,process for their preparation and their use as antitumour agents |
| GB0011059D0 (en) * | 2000-05-08 | 2000-06-28 | Pharmacia & Upjohn Spa | Use of substituted acryloyl distamycin derivatives in the treatment of tumours associated with high levels of glutathione |
| US6576612B1 (en) * | 2000-10-02 | 2003-06-10 | Pharmacia Italia S.P.A. | Antitumor therapy comprising distamycin derivatives |
| US6887851B2 (en) * | 2001-09-18 | 2005-05-03 | Bioexpertise, Llc | IGF-binding protein-derived peptide |
| NZ535700A (en) * | 2002-04-02 | 2007-06-29 | Nerviano Medical Sciences Srl | Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and radiotherapy |
-
2000
- 2000-06-23 GB GBGB0015446.8A patent/GB0015446D0/en not_active Ceased
-
2001
- 2001-06-20 AT AT01945297T patent/ATE415165T1/de not_active IP Right Cessation
- 2001-06-20 HU HU0301334A patent/HUP0301334A3/hu unknown
- 2001-06-20 CN CNB018116078A patent/CN100479824C/zh not_active Expired - Fee Related
- 2001-06-20 SK SK1829-2002A patent/SK287398B6/sk not_active IP Right Cessation
- 2001-06-20 AU AU2001267553A patent/AU2001267553B2/en not_active Ceased
- 2001-06-20 CA CA002412054A patent/CA2412054A1/en not_active Abandoned
- 2001-06-20 DE DE60136706T patent/DE60136706D1/de not_active Expired - Lifetime
- 2001-06-20 AU AU6755301A patent/AU6755301A/xx active Pending
- 2001-06-20 ES ES01945297T patent/ES2317913T3/es not_active Expired - Lifetime
- 2001-06-20 NZ NZ523001A patent/NZ523001A/en unknown
- 2001-06-20 KR KR1020027017409A patent/KR100861668B1/ko not_active IP Right Cessation
- 2001-06-20 EP EP01945297A patent/EP1299110B1/en not_active Expired - Lifetime
- 2001-06-20 CZ CZ20024107A patent/CZ20024107A3/cs unknown
- 2001-06-20 MX MXPA02012165A patent/MXPA02012165A/es active IP Right Grant
- 2001-06-20 DE DE60143681T patent/DE60143681D1/de not_active Expired - Lifetime
- 2001-06-20 NZ NZ543318A patent/NZ543318A/en unknown
- 2001-06-20 EE EEP200200688A patent/EE05359B1/xx not_active IP Right Cessation
- 2001-06-20 PL PL363696A patent/PL200504B1/pl not_active IP Right Cessation
- 2001-06-20 US US10/297,620 patent/US7642229B2/en not_active Expired - Fee Related
- 2001-06-20 EP EP07122497A patent/EP1889624B1/en not_active Expired - Lifetime
- 2001-06-20 EA EA200300059A patent/EA006709B1/ru not_active IP Right Cessation
- 2001-06-20 JP JP2002503104A patent/JP2003535874A/ja not_active Withdrawn
- 2001-06-20 WO PCT/EP2001/007060 patent/WO2001097618A2/en active Application Filing
- 2001-06-20 IL IL15317801A patent/IL153178A0/xx unknown
- 2001-06-20 AT AT07122497T patent/ATE491457T1/de not_active IP Right Cessation
- 2001-06-20 BR BR0111814-5A patent/BR0111814A/pt not_active Application Discontinuation
-
2002
- 2002-11-28 IL IL153178A patent/IL153178A/en not_active IP Right Cessation
- 2002-12-04 ZA ZA200209835A patent/ZA200209835B/xx unknown
- 2002-12-18 NO NO20026076A patent/NO329967B1/no not_active IP Right Cessation
-
2003
- 2003-09-22 HK HK03106774.6A patent/HK1054506B/zh not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |