DK1292290T3 - Kombineret terapi mod tumorer omfattende substitueret acryloyl distamycinderivater og topoisomerase I og II inhibitorer - Google Patents

Kombineret terapi mod tumorer omfattende substitueret acryloyl distamycinderivater og topoisomerase I og II inhibitorer

Info

Publication number
DK1292290T3
DK1292290T3 DK01956495T DK01956495T DK1292290T3 DK 1292290 T3 DK1292290 T3 DK 1292290T3 DK 01956495 T DK01956495 T DK 01956495T DK 01956495 T DK01956495 T DK 01956495T DK 1292290 T3 DK1292290 T3 DK 1292290T3
Authority
DK
Denmark
Prior art keywords
topoisomerase
inhibitors
distamycin derivatives
acryloyl distamycin
combined therapy
Prior art date
Application number
DK01956495T
Other languages
English (en)
Inventor
Maria Cristina Rosa Geroni
Paolo Cozzi
Italo Beria
Original Assignee
Nerviano Medical Sciences Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nerviano Medical Sciences Srl filed Critical Nerviano Medical Sciences Srl
Application granted granted Critical
Publication of DK1292290T3 publication Critical patent/DK1292290T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DK01956495T 2000-06-23 2001-06-20 Kombineret terapi mod tumorer omfattende substitueret acryloyl distamycinderivater og topoisomerase I og II inhibitorer DK1292290T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0015444.3A GB0015444D0 (en) 2000-06-23 2000-06-23 Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors

Publications (1)

Publication Number Publication Date
DK1292290T3 true DK1292290T3 (da) 2006-07-10

Family

ID=9894285

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01956495T DK1292290T3 (da) 2000-06-23 2001-06-20 Kombineret terapi mod tumorer omfattende substitueret acryloyl distamycinderivater og topoisomerase I og II inhibitorer

Country Status (27)

Country Link
US (1) US20030162722A1 (da)
EP (1) EP1292290B1 (da)
JP (1) JP2003535890A (da)
KR (1) KR100853955B1 (da)
CN (1) CN1241573C (da)
AT (1) ATE323483T1 (da)
AU (2) AU2001278463B2 (da)
BR (1) BR0111813A (da)
CA (1) CA2411172C (da)
CZ (1) CZ20024155A3 (da)
DE (1) DE60118914T2 (da)
DK (1) DK1292290T3 (da)
EA (1) EA006684B1 (da)
EE (1) EE05319B1 (da)
ES (1) ES2261448T3 (da)
GB (1) GB0015444D0 (da)
HK (1) HK1054334B (da)
HU (1) HUP0301257A2 (da)
IL (1) IL153177A0 (da)
MX (1) MXPA02012163A (da)
NO (1) NO329783B1 (da)
NZ (1) NZ523000A (da)
PL (1) PL200503B1 (da)
PT (1) PT1292290E (da)
SK (1) SK287549B6 (da)
WO (1) WO2001097789A2 (da)
ZA (1) ZA200209834B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0015447D0 (en) * 2000-06-23 2000-08-16 Pharmacia & Upjohn Spa Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents
GB0015444D0 (en) * 2000-06-23 2000-08-16 Pharmacia & Upjohn Spa Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors
PT1461083E (pt) * 2002-01-02 2006-08-31 Nerviano Medical Sciences Srl Terapia combinada contra tumores que compreende derivados de distamicina de acriloilo substituidos e de inibidores de proteina-quinase (serina/treonina-quinase)
CN100438913C (zh) * 2004-11-22 2008-12-03 山东蓝金生物工程有限公司 一种抗癌药物组合物
MD23Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de tratament diferenţiat al carcinomului lobular in situ neinvaziv al glandei mamare
MD36Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de tratament diferenţiat al carcinomului ductal in situ neinvaziv al glandei mamare
MD24Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de tratament diferenţiat al carcinomului neinvaziv al glandei mamare
MD35Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de apreciere a riscului dezvoltării carcinomului neinvaziv in situ al glandei mamare
RU2013103763A (ru) 2010-07-02 2014-08-10 Ангиохем Инк. Короткие и содержащие d-аминокислоты полипептиды для терапевтических конъюгатов и их применения
CN109718228A (zh) * 2017-10-30 2019-05-07 沈阳药科大学 米托蒽醌的抗肿瘤淋巴转移作用及其药物制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9615692D0 (en) * 1996-07-25 1996-09-04 Pharmacia Spa Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents
GB9623522D0 (en) 1996-11-11 1997-01-08 Pharmacia & Upjohn Spa Benzoheterocycle distamycin derivatives process for preparing them and their use as antitumour and antiviral agents
GB9727524D0 (en) * 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Synergistic antitumor composition containing a biologically active ureido compound
GB9806692D0 (en) * 1998-03-27 1998-05-27 Pharmacia & Upjohn Spa Benzoheterocyclic distamycin derivatives, process for preparing them and their use as antitumour agents
GB0015444D0 (en) * 2000-06-23 2000-08-16 Pharmacia & Upjohn Spa Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors

Also Published As

Publication number Publication date
EE200200681A (et) 2004-06-15
JP2003535890A (ja) 2003-12-02
NZ523000A (en) 2005-12-23
PL200503B1 (pl) 2009-01-30
PL360297A1 (en) 2004-09-06
EP1292290B1 (en) 2006-04-19
IL153177A0 (en) 2003-06-24
CN1437474A (zh) 2003-08-20
ZA200209834B (en) 2003-12-04
SK287549B6 (sk) 2011-01-04
HK1054334A1 (en) 2003-11-28
CA2411172C (en) 2009-11-17
KR100853955B1 (ko) 2008-08-25
US20030162722A1 (en) 2003-08-28
BR0111813A (pt) 2003-05-20
MXPA02012163A (es) 2003-04-25
CN1241573C (zh) 2006-02-15
NO329783B1 (no) 2010-12-13
CA2411172A1 (en) 2001-12-27
EA006684B1 (ru) 2006-02-24
ES2261448T3 (es) 2006-11-16
GB0015444D0 (en) 2000-08-16
ATE323483T1 (de) 2006-05-15
SK18332002A3 (sk) 2003-07-01
EP1292290A2 (en) 2003-03-19
AU7846301A (en) 2002-01-02
PT1292290E (pt) 2006-08-31
NO20026078L (no) 2002-12-18
AU2001278463B2 (en) 2006-02-23
WO2001097789A2 (en) 2001-12-27
DE60118914D1 (de) 2006-05-24
DE60118914T2 (de) 2006-12-21
CZ20024155A3 (cs) 2003-04-16
EA200300060A1 (ru) 2003-04-24
KR20030019448A (ko) 2003-03-06
HK1054334B (zh) 2006-09-22
HUP0301257A2 (hu) 2003-08-28
EE05319B1 (et) 2010-08-16
WO2001097789A3 (en) 2002-05-16
NO20026078D0 (no) 2002-12-18

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