ITMI960338A0 - - Google Patents
Info
- Publication number
- ITMI960338A0 ITMI960338A0 ITMI960338A ITMI960338A ITMI960338A0 IT MI960338 A0 ITMI960338 A0 IT MI960338A0 IT MI960338 A ITMI960338 A IT MI960338A IT MI960338 A ITMI960338 A IT MI960338A IT MI960338 A0 ITMI960338 A0 IT MI960338A0
- Authority
- IT
- Italy
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Priority Applications (24)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT96MI000338A IT1282673B1 (it) | 1996-02-23 | 1996-02-23 | Derivati della camptotecina e loro uso come agenti antitumorali |
US09/125,512 US6130227A (en) | 1996-02-23 | 1997-02-19 | 7-Substituted camptothecin derivatives and methods for inhibiting the growth of tumor cells therewith |
AU18753/97A AU718361B2 (en) | 1996-02-23 | 1997-02-19 | Camptothecin derivatives and the use thereof as antitumor agents |
UA98084449A UA49005C2 (uk) | 1996-02-23 | 1997-02-19 | Похідні камптотецину (варіанти), спосіб їх одержання (варіанти) та фармацевтична композиція на їх основі |
AT97905057T ATE221071T1 (de) | 1996-02-23 | 1997-02-19 | Campotecinderivate und ihre verwendung als antitumormittel |
CA002247513A CA2247513C (en) | 1996-02-23 | 1997-02-19 | Camptothecin derivatives and the use thereof as antitumor agents |
CN97192493A CN1107677C (zh) | 1996-02-23 | 1997-02-19 | 喜树碱衍生物和制备方法及其作为抗肿瘤剂的应用 |
ES97905057T ES2180932T3 (es) | 1996-02-23 | 1997-02-19 | Derivados de camptotecina y su uso como agentes antitumorales. |
EP97905057A EP0885230B1 (en) | 1996-02-23 | 1997-02-19 | Camptothecin derivatives and the use thereof as antitumor agents |
KR1019980706498A KR100497906B1 (ko) | 1996-02-23 | 1997-02-19 | 캄토테신유도체와이를활성성분으로하는항암제 |
BRPI9707622-8A BR9707622B1 (pt) | 1996-02-23 | 1997-02-19 | derivados de camptotecina, bem como composição farmacêutica compreendendo os mesmos. |
IL12585697A IL125856A (en) | 1996-02-23 | 1997-02-19 | 7-substituted camptothecin derivatives, their preparation and pharmaceutical compositions containing them |
PCT/EP1997/000786 WO1997031003A1 (en) | 1996-02-23 | 1997-02-19 | Camptothecin derivatives and the use thereof as antitumor agents |
JP52979197A JP4171527B2 (ja) | 1996-02-23 | 1997-02-19 | カンプトテシン誘導体及び抗腫瘍剤としてのその利用 |
EE9800259A EE03529B1 (et) | 1996-02-23 | 1997-02-19 | Kamptotetsiinderivaadid, nende valmistamise meetod ja kasutamine kasvajavastaste ainetena |
NZ331126A NZ331126A (en) | 1996-02-23 | 1997-02-19 | Camptothecin derivatives and the use thereof as antitumor agents |
PT97905057T PT885230E (pt) | 1996-02-23 | 1997-02-19 | Derivados de camptotecina e sua utilizacao como agentes antitumorais |
SK1127-98A SK283217B6 (sk) | 1996-02-23 | 1997-02-19 | Kamptotecínové deriváty, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a ich použitie |
RU98117449/04A RU2165935C2 (ru) | 1996-02-23 | 1997-02-19 | Производные камптотецина, их n-оксиды, способы их получения и фармацевтическая композиция |
CZ19982652A CZ289268B6 (cs) | 1996-02-23 | 1997-02-19 | Deriváty camptothecinu, způsob výroby a farmaceutický prostředek |
HU9900987A HUP9900987A3 (en) | 1996-02-23 | 1997-02-19 | Camptothecin derivatives process for their preparation, use thereof as antitumor agents and pharmaceutical compositions containing them |
DE69714220T DE69714220T2 (de) | 1996-02-23 | 1997-02-19 | Campotecinderivate und ihre verwendung als antitumormittel |
DK97905057T DK0885230T3 (da) | 1996-02-23 | 1997-02-19 | Camptothecinderivater og deres anvendelse som antitumormidler |
US09/643,256 US6306868B1 (en) | 1996-02-23 | 2000-08-22 | Methods for inhibiting the growth of tumors with 7-substituted camptothecin derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT96MI000338A IT1282673B1 (it) | 1996-02-23 | 1996-02-23 | Derivati della camptotecina e loro uso come agenti antitumorali |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI960338A0 true ITMI960338A0 (ko) | 1996-02-23 |
ITMI960338A1 ITMI960338A1 (it) | 1997-08-23 |
IT1282673B1 IT1282673B1 (it) | 1998-03-31 |
Family
ID=11373368
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT96MI000338A IT1282673B1 (it) | 1996-02-23 | 1996-02-23 | Derivati della camptotecina e loro uso come agenti antitumorali |
Country Status (22)
Country | Link |
---|---|
US (2) | US6130227A (ko) |
EP (1) | EP0885230B1 (ko) |
JP (1) | JP4171527B2 (ko) |
KR (1) | KR100497906B1 (ko) |
CN (1) | CN1107677C (ko) |
AT (1) | ATE221071T1 (ko) |
AU (1) | AU718361B2 (ko) |
BR (1) | BR9707622B1 (ko) |
CZ (1) | CZ289268B6 (ko) |
DE (1) | DE69714220T2 (ko) |
DK (1) | DK0885230T3 (ko) |
EE (1) | EE03529B1 (ko) |
ES (1) | ES2180932T3 (ko) |
HU (1) | HUP9900987A3 (ko) |
IL (1) | IL125856A (ko) |
IT (1) | IT1282673B1 (ko) |
NZ (1) | NZ331126A (ko) |
PT (1) | PT885230E (ko) |
RU (1) | RU2165935C2 (ko) |
SK (1) | SK283217B6 (ko) |
UA (1) | UA49005C2 (ko) |
WO (1) | WO1997031003A1 (ko) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000000238A1 (en) * | 1998-06-26 | 2000-01-06 | Quanam Medical Corporation | Topoisomerase inhibitors for prevention of restenosis |
ATE216998T1 (de) * | 1999-03-09 | 2002-05-15 | Sigma Tau Ind Farmaceuti | Camptothecin-derivate mit antitumor-wirkung |
US7105492B2 (en) * | 1999-03-09 | 2006-09-12 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Camptothecin derivatives having antitumor activity |
AR025587A1 (es) | 1999-09-13 | 2002-12-04 | Hoffmann La Roche | Formulaciones en dispersion que contienen inhibidores de lipasa |
AU2002258787A1 (en) * | 2001-04-11 | 2002-10-28 | Emerald Biostructures, Inc. | Screening methods for identifying ligands |
US7067666B2 (en) * | 2003-06-27 | 2006-06-27 | Research Triangle Institute | 7-substituted camptothecin and camptothecin analogs and methods for producing the same |
ITRM20030344A1 (it) * | 2003-07-14 | 2005-01-15 | Ist Naz Stud Cura Dei Tumori | 7-n-poliamminoalchil(ossi)imminometilcamptotecine recanti gruppi protettivi. |
JP5657205B2 (ja) * | 2005-12-21 | 2015-01-21 | シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニSigma−Tau Industrie Farmaceutiche Riunite Societa Per Azioni | 薬物耐性腫瘍の治療 |
WO2007095389A2 (en) * | 2006-02-17 | 2007-08-23 | Novacea, Inc. | Treatment of hyperproliferative diseases with camptothecine n-oxide and analogs |
CN101033230B (zh) | 2006-03-10 | 2010-12-08 | 中国科学院上海药物研究所 | 一类喜树碱衍生物及其应用 |
ITMI20061474A1 (it) * | 2006-07-26 | 2008-01-27 | Indena Spa | Derivati della camptotecina ad attivita antitumorale |
CN102731516B (zh) * | 2011-04-07 | 2014-07-02 | 宁波天衡药业股份有限公司 | 一类具有抗肿瘤活性的喜树碱衍生物 |
CN104774209B (zh) * | 2014-01-15 | 2018-06-19 | 上海海和药物研究开发有限公司 | 一种9-烯丙基喜树碱衍生物的合成方法 |
CN117940432A (zh) * | 2021-09-01 | 2024-04-26 | 上海弼领生物技术有限公司 | 一种喜树碱类化合物、其制备方法和用途 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4399282A (en) * | 1979-07-10 | 1983-08-16 | Kabushiki Kaisha Yakult Honsha | Camptothecin derivatives |
JPS58154582A (ja) * | 1982-03-10 | 1983-09-14 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体およびその製造法 |
US5726181A (en) * | 1995-06-05 | 1998-03-10 | Bionumerik Pharmaceuticals, Inc. | Formulations and compositions of poorly water soluble camptothecin derivatives |
JP4364305B2 (ja) * | 1996-08-19 | 2009-11-18 | バイオニューメリック ファーマシューティカルズ インク | 極めて脂肪親和性のカンプトテシン誘導体 |
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1996
- 1996-02-23 IT IT96MI000338A patent/IT1282673B1/it active IP Right Grant
-
1997
- 1997-02-19 RU RU98117449/04A patent/RU2165935C2/ru not_active IP Right Cessation
- 1997-02-19 CZ CZ19982652A patent/CZ289268B6/cs not_active IP Right Cessation
- 1997-02-19 SK SK1127-98A patent/SK283217B6/sk not_active IP Right Cessation
- 1997-02-19 EE EE9800259A patent/EE03529B1/xx not_active IP Right Cessation
- 1997-02-19 UA UA98084449A patent/UA49005C2/uk unknown
- 1997-02-19 WO PCT/EP1997/000786 patent/WO1997031003A1/en not_active Application Discontinuation
- 1997-02-19 BR BRPI9707622-8A patent/BR9707622B1/pt not_active IP Right Cessation
- 1997-02-19 DK DK97905057T patent/DK0885230T3/da active
- 1997-02-19 DE DE69714220T patent/DE69714220T2/de not_active Expired - Lifetime
- 1997-02-19 JP JP52979197A patent/JP4171527B2/ja not_active Expired - Fee Related
- 1997-02-19 KR KR1019980706498A patent/KR100497906B1/ko not_active IP Right Cessation
- 1997-02-19 US US09/125,512 patent/US6130227A/en not_active Expired - Fee Related
- 1997-02-19 NZ NZ331126A patent/NZ331126A/en not_active IP Right Cessation
- 1997-02-19 AU AU18753/97A patent/AU718361B2/en not_active Ceased
- 1997-02-19 PT PT97905057T patent/PT885230E/pt unknown
- 1997-02-19 HU HU9900987A patent/HUP9900987A3/hu unknown
- 1997-02-19 IL IL12585697A patent/IL125856A/xx not_active IP Right Cessation
- 1997-02-19 AT AT97905057T patent/ATE221071T1/de not_active IP Right Cessation
- 1997-02-19 CN CN97192493A patent/CN1107677C/zh not_active Expired - Fee Related
- 1997-02-19 ES ES97905057T patent/ES2180932T3/es not_active Expired - Lifetime
- 1997-02-19 EP EP97905057A patent/EP0885230B1/en not_active Expired - Lifetime
-
2000
- 2000-08-22 US US09/643,256 patent/US6306868B1/en not_active Expired - Fee Related
Also Published As
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Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970529 |