ITMI20020148A0 - Nuovi corticosteroidi - Google Patents
Nuovi corticosteroidiInfo
- Publication number
- ITMI20020148A0 ITMI20020148A0 IT2002MI000148A ITMI20020148A ITMI20020148A0 IT MI20020148 A0 ITMI20020148 A0 IT MI20020148A0 IT 2002MI000148 A IT2002MI000148 A IT 2002MI000148A IT MI20020148 A ITMI20020148 A IT MI20020148A IT MI20020148 A0 ITMI20020148 A0 IT MI20020148A0
- Authority
- IT
- Italy
- Prior art keywords
- corticosteroids
- new
- new corticosteroids
- Prior art date
Links
- 239000003246 corticosteroid Substances 0.000 title 1
- 229960001334 corticosteroids Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2002MI000148A ITMI20020148A1 (it) | 2002-01-29 | 2002-01-29 | Nuovi corticosteroidi |
US10/501,335 US20060052594A1 (en) | 2002-01-29 | 2003-01-16 | New corticosteroids |
CA002473249A CA2473249A1 (en) | 2002-01-29 | 2003-01-16 | New corticosteroids |
PCT/EP2003/000394 WO2003064443A2 (en) | 2002-01-29 | 2003-01-16 | New corticosteroids |
AU2003210161A AU2003210161B2 (en) | 2002-01-29 | 2003-01-16 | New corticosteroids |
BR0307027-1A BR0307027A (pt) | 2002-01-29 | 2003-01-16 | Compostos derivados de nitróxi de compostos esteróides, uso dos compostos, e, formulações farmacêuticas |
JP2003564063A JP2005516070A (ja) | 2002-01-29 | 2003-01-16 | 新規なコルチコステロイド類 |
EP03734674A EP1470150A2 (en) | 2002-01-29 | 2003-01-16 | Corticosteroids nitrate derivatives |
MXPA04007337A MXPA04007337A (es) | 2002-01-29 | 2003-01-16 | Corticosteroides novedosos. |
NZ534147A NZ534147A (en) | 2002-01-29 | 2003-01-16 | New corticosteroids |
PL03370457A PL370457A1 (en) | 2002-01-29 | 2003-01-16 | New corticosteroids |
NO20043595A NO327364B1 (no) | 2002-01-29 | 2004-08-27 | Nitrooksyderivater av steroidforbindelser, anvendelse derav, og farmasoytisk formulering omfattende slike |
AU2008258133A AU2008258133A1 (en) | 2002-01-29 | 2008-12-15 | New corticosteroids |
US12/464,562 US20090221543A1 (en) | 2002-01-29 | 2009-05-12 | New corticosteroids |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2002MI000148A ITMI20020148A1 (it) | 2002-01-29 | 2002-01-29 | Nuovi corticosteroidi |
Publications (2)
Publication Number | Publication Date |
---|---|
ITMI20020148A0 true ITMI20020148A0 (it) | 2002-01-29 |
ITMI20020148A1 ITMI20020148A1 (it) | 2003-07-29 |
Family
ID=11449016
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT2002MI000148A ITMI20020148A1 (it) | 2002-01-29 | 2002-01-29 | Nuovi corticosteroidi |
Country Status (12)
Country | Link |
---|---|
US (2) | US20060052594A1 (it) |
EP (1) | EP1470150A2 (it) |
JP (1) | JP2005516070A (it) |
AU (2) | AU2003210161B2 (it) |
BR (1) | BR0307027A (it) |
CA (1) | CA2473249A1 (it) |
IT (1) | ITMI20020148A1 (it) |
MX (1) | MXPA04007337A (it) |
NO (1) | NO327364B1 (it) |
NZ (1) | NZ534147A (it) |
PL (1) | PL370457A1 (it) |
WO (1) | WO2003064443A2 (it) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI1691804T1 (sl) * | 2003-12-02 | 2007-10-31 | Nicox Sa | Nitrooksi derivati karvedilola in drugih beta blokatorjev kot antihipertenzivi |
RU2415864C2 (ru) * | 2005-09-02 | 2011-04-10 | Никокс С.А. | Нитрооксипроизводные стероидов |
US8802726B2 (en) | 2006-02-03 | 2014-08-12 | Nicox S.A. | Use of nitrooxyderivative of drug for the treatment of muscular dystrophies |
ES2601102T3 (es) | 2007-02-05 | 2017-02-14 | Nicox S.A. | Esteroides que liberan óxido nítrico |
EP1964550A1 (en) * | 2007-03-01 | 2008-09-03 | NicOx S.A. | Glucocorticoid-nitrooxyderivative compositions |
CA2695435A1 (en) * | 2007-08-10 | 2009-03-26 | Nicox S.A. | Combination of nitroderivatized steroid and bronchodilator for treating respiratory disease |
US20090088411A1 (en) * | 2007-08-31 | 2009-04-02 | Topigen Pharmaceuticals Inc. | No-donating corticosteroid with improved pharmacokinetic, anti-inflammatory and vasodilatory properties |
ES2324007A1 (es) * | 2007-10-25 | 2009-07-28 | Ferrer Internacional, S.A. | Una forma amorfa de un compuesto antiinflamatorio. |
WO2009141738A2 (en) * | 2008-05-23 | 2009-11-26 | The University Of British Columbia | Modified drugs for use in liposomal nanoparticles |
CN101624414B (zh) * | 2008-07-07 | 2013-02-13 | 天津金耀集团有限公司 | 一种抑制血管新生的硝酸酯药物 |
KR20110041496A (ko) | 2008-07-31 | 2011-04-21 | 니콕스 에스. 에이. | 위치 21에 있는 방향족 링커(linker)를 통해 질산 에스테르에 부착된 당질코르티코이드 및 그들의 안과에의 용도 |
EP2321333A1 (en) | 2008-08-05 | 2011-05-18 | Nicox S.A. | New no-releasing steroids for the treatment of retina and macula lutea diseases |
CN102040643B (zh) * | 2009-10-16 | 2013-01-09 | 天津金耀集团有限公司 | 环索奈德硝酸酯衍生物 |
CN102302501B (zh) * | 2010-06-07 | 2012-10-03 | 刘超 | 糖皮质激素硝基衍生物在制备利尿药物制剂中的应用 |
SG10202104259RA (en) | 2016-11-08 | 2021-06-29 | Regeneron Pharma | Steroids and protein-conjugates thereof |
US11491237B2 (en) | 2017-05-18 | 2022-11-08 | Regeneron Pharmaceuticals, Inc. | Cyclodextrin protein drug conjugates |
CN108484714A (zh) * | 2018-03-13 | 2018-09-04 | 岳阳环宇药业有限公司 | 地夫可特的制备工艺 |
KR20210008008A (ko) | 2018-05-09 | 2021-01-20 | 리제너론 파마슈티칼스 인코포레이티드 | 항-msr1 항체 및 이의 사용 방법 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1037451B (de) * | 1957-04-04 | 1958-08-28 | Schering Ag | Verfahren zur Herstellung der Aminoacetate von gesaettigten und ungesaettigten 21-Hydroxypregnan-verbindungen bzw. deren wasserloeslichen Saeureadditionsprodukten |
US3183252A (en) * | 1963-09-05 | 1965-05-11 | Syntex Corp | 16-nitratoalkyl-pregnanes |
US3494941A (en) | 1967-12-04 | 1970-02-10 | American Home Prod | Nitrate esters of 17beta-(hydroxyalkoxy)steroid 3-ols,3-ones and 3-amidinohydrazones |
HU164115B (it) | 1971-05-07 | 1973-12-28 | ||
DE3260474D1 (en) * | 1981-02-02 | 1984-09-06 | Schering Corp | Aromatic heterocyclic esters of steroids, their preparation and pharmaceutical compositions containing them |
GR1001529B (el) * | 1990-09-07 | 1994-03-31 | Elmuquimica Farm Sl | Μέ?οδος για την λήψη νέων 21-εστέρων της 16-17-ακετάλης της πρ να-1,4-διενο-3,20-διόνης. |
US5824669A (en) * | 1996-03-22 | 1998-10-20 | Nitromed, Inc. | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders |
US5837698A (en) * | 1996-05-02 | 1998-11-17 | G. D. Searle & Co. | Steroid nitrite and nitrate ester derivatives useful as anti-inflammatory drugs |
IT1285770B1 (it) | 1996-10-04 | 1998-06-18 | Nicox Sa | Composti corticoidei |
US6248723B1 (en) * | 1997-06-10 | 2001-06-19 | National Jewish Medical And Research Center | Method for treatment of inflammatory disease |
US6254853B1 (en) * | 1998-05-08 | 2001-07-03 | Vyrex Corporation | Water soluble pro-drugs of propofol |
IT1311922B1 (it) | 1999-04-13 | 2002-03-20 | Nicox Sa | Composti farmaceutici. |
IT1320176B1 (it) * | 2000-12-22 | 2003-11-26 | Nicox Sa | Dispersioni solide di principi attivi nitrati. |
EP1336602A1 (en) * | 2002-02-13 | 2003-08-20 | Giovanni Scaramuzzino | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases |
-
2002
- 2002-01-29 IT IT2002MI000148A patent/ITMI20020148A1/it unknown
-
2003
- 2003-01-16 NZ NZ534147A patent/NZ534147A/en not_active IP Right Cessation
- 2003-01-16 BR BR0307027-1A patent/BR0307027A/pt not_active IP Right Cessation
- 2003-01-16 CA CA002473249A patent/CA2473249A1/en not_active Abandoned
- 2003-01-16 WO PCT/EP2003/000394 patent/WO2003064443A2/en active Application Filing
- 2003-01-16 PL PL03370457A patent/PL370457A1/xx unknown
- 2003-01-16 JP JP2003564063A patent/JP2005516070A/ja active Pending
- 2003-01-16 AU AU2003210161A patent/AU2003210161B2/en not_active Ceased
- 2003-01-16 US US10/501,335 patent/US20060052594A1/en not_active Abandoned
- 2003-01-16 EP EP03734674A patent/EP1470150A2/en not_active Ceased
- 2003-01-16 MX MXPA04007337A patent/MXPA04007337A/es unknown
-
2004
- 2004-08-27 NO NO20043595A patent/NO327364B1/no not_active IP Right Cessation
-
2008
- 2008-12-15 AU AU2008258133A patent/AU2008258133A1/en not_active Abandoned
-
2009
- 2009-05-12 US US12/464,562 patent/US20090221543A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2473249A1 (en) | 2003-08-07 |
NO20043595L (no) | 2004-10-20 |
US20090221543A1 (en) | 2009-09-03 |
US20060052594A1 (en) | 2006-03-09 |
WO2003064443A3 (en) | 2004-02-26 |
BR0307027A (pt) | 2004-11-03 |
AU2003210161B2 (en) | 2008-12-04 |
AU2008258133A1 (en) | 2009-01-08 |
PL370457A1 (en) | 2005-05-30 |
JP2005516070A (ja) | 2005-06-02 |
NO327364B1 (no) | 2009-06-15 |
NZ534147A (en) | 2006-09-29 |
MXPA04007337A (es) | 2004-11-26 |
WO2003064443A2 (en) | 2003-08-07 |
ITMI20020148A1 (it) | 2003-07-29 |
EP1470150A2 (en) | 2004-10-27 |
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